• Journal of Welding and Joining
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• v.35 no.2
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• pp.43-51
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• 2017

The automatic welding systems, have received much attention in recent years, because they are highly suitable not only to increase the quality and productivity, but also to decrease manufacturing time and cost for a given product. Automatic welding work in semiconductor or space industry to be carried out in pipe line and butt joint mostly and plasma arc welding(PAW) is actively applied. To get the desired quality welds in automated welding system is challenging, a mathematical model is needed that has complete control over the relevant process parameters in order to obtain the required mechanical properties. However, In various industries the welding process mathematical model is not fully formulated for the process parameter and on the welding conditions, therefore only partial variables can be predicted. Therefore, this paper investigates the interaction between the welding parameters and mechanical properties for predicting the weld bead geometry by analyzing the S/N ratio.

• Microbiology and Biotechnology Letters
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• v.16 no.5
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• pp.389-392
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• 1988

A clone pSL 2-1, which is a recombinant plasmid believed to contain the mosquitocidal crystal-line protein gene of the Bacillus sphaericus 1593, was expressed in Escherichia coli JM83 and the product of the clone was purified and identified. The unsolubilized mosquitocidal crystal proteins from the B. sphaericus had formed 43, 58, 64, 100, 113, and 130 Kd bands in the SDS-polyacrylamide gel, but the NaOH-solublized proteins at pH 12 formed 2 protein bands of 43- and 64Kd in the gel because the larger protein (precursor) bands were cleaved. The products of the pSL 2-1 clone was purified by Sephadex G-200 and only the fractions having lethal activity to the 3rd in-star larvae of mosquito Culex pipiens were analyzed by the gel. The only single protein band of 42 Kd toxic to the larvae was formed. The major toxic protein being produced from the B. sphaericus 1593 and the pSL 2-1 clone was found to be the 42 Kd.

• Journal of Microbiology and Biotechnology
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• v.18 no.11
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• pp.1862-1867
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• 2008

Streptochlorin is a small molecule isolated from marine Streptomyces sp. that is known to have antiangiogenic and anticancer properties. In this study, we examined the effects of this compound on reactive oxygen species (ROS) production and the association of these effects with apoptotic tumor cell death, using a human hepatocarcinoma Hep3B cell line. The results of this study demonstrated that streptochlorin mediates ROS production, and that this mediation is followed by a decrease in the mitochondrial membrane potential (MMP, ${\Delta}{\Psi}_m$), activation of caspase-3, and downregulation of antiapoptotic Bcl-2 protein. The quenching of ROS generation by N-acetyl-L-cysteine administration, a scavenger of ROS, reversed the streptochlorin-induced apoptosis effects via inhibition of ROS production, MMP collapse, and the subsequent activation of caspase-3. These observations clearly indicate that ROS are involved in the early molecular events in the streptochlorin-induced apoptotic pathway. Taken together, our data imply that streptochlorin-induced ROS is a key mediator of MMP collapse, which leads to the caspase-3 activation, culminating in apoptosis.

• Journal of Microbiology and Biotechnology
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• v.30 no.11
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• pp.1769-1776
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• 2020

As part of our current work to discover structurally and/or biologically novel compounds from Korean wild mushrooms, we isolated five ergostane-type steroids (1-5) from the fruiting bodies of Xerula furfuracea via repeated column chromatographic separations and HPLC purification. The chemical structures of the isolated steroids were shown to be (22E,24R)-24-methylcholesta-4,22-diene-3,6-dione (1), ergosta-7,22-diene-3β,5α,6β-triol (2), ergosta-7,22-diene-3β,5α,6β,9α-tetraol (3), (22E,24R)-5α,8α-epidioxyergosta-6,22-diene-3β-ol-3-O-β-D-glucopyranoside (4), and (22E,24R)-5α,8α-epidioxyergosta-6,9,22-triene-3β-ol-3-O-β-D-glucopyranoside (5)based on comparison of the data regarding their spectroscopic and physical properties with those of previous studies. Notably, this is the first report on the presence of the identified steroids (1-5) in this mushroom. We tested compounds 1-5 to determine their effects on adipogenesis and osteogenesis in the mouse mesenchymal stem cell line C3H10T1/2 and found that compounds 4 and 5 suppressed the differentiation of stem cells into adipocytes. Notably, in addition to its suppressive effect on adipogenesis, compound 5 was also shown to promote the osteogenic differentiation of stem cells. These findings demonstrate that the bioactive compounds isolated might be effective for the treatment of menopause-associated syndromes, such as osteoporosis and obesity, as the isolated compounds were shown to suppress adipogenesis and/or promote osteogenesis of stem cells.

• Journal of the Korean Institute of Intelligent Systems
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• v.18 no.2
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• pp.230-235
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• 2008

Recently, LG chemical corporation developed new material called HYPERIER, which has an excellent barrier characteristic. It has many layers which are made of nano-composite within LDPE(Low-Density Poly Ethylene). In order to guarantee the quality of the final product from the production line, a certain test equipment is required to investigate the existence of layers inside the HYPERIER. In this work, ultrasonic sensor based test equipment for investigating the existence of inner layers is proposed. However, it is a tedious job for human operators to check the existence by just looking at the resounding waveform from ultrasonic sensor. Therefore, to enhance the performance of the ultrasonic test equipment, Fast Fourier Transform(FFT) and Principle Components Analysis(PCA) and Back-Propagation Neural Network(BPNN) are utilized which is used for classification of Quality. To verily the feasibility of the proposed scheme, some experiments are executed.

• Journal of Ginseng Research
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• v.39 no.2
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• pp.94-104
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• 2015

Background: Ginseng (Panax ginseng Meyer) is an important medicinal herbs in Asia. However, ginseng varieties are less developed. Method: To developed ginseng varieties, a pure line selection method was applied in this study. Results: Gumpoong was testing of 4-yr-old specimens in 2002, the proportions of the below-ground roots that were rusty colored for Gumpoong was 1.29 in Daejeon and 1.45 in Eumseong, whereas the proportions for its yellow berry variant were 2.60 and 2.45 in the two regions, respectively. Thus the Gumpoong was resistant to root rust. Sunpoong has a high yielding property. Its average root weight is 70.6 g for 6-yr-old roots. Its yield is 2.9 kg/$1.62m^2$ and the rate of heaven- and earth-grade product is 20.9%, which is very high compared to 9.4% for Yunpoong. Sunone is resistance to root rot and the survival rate of 4-yr-old roots was 44.4% in 1997, whereas that of the violet-stem variant landrace was 21.7%. Sunhyang has content of arginyl-fructosyl-glucose (AFG), which produces the unique scent of red ginseng, is $95.1{\mu}mol/g$ and greater than the $30.8{\mu}mol/g$ of Chunpoong in 6-yr-old plants. Sunun and Cheongsun are being nurtured to protect genetic resources. Conclusion: Developed ginsneg varieties will be used as the basis for the protection of genetic resources and breeding.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.4
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• pp.55-66
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• 2017

Korean small and medium sized software companies have tried to export their solutions or services to overseas markets. In 2016, exports of the software industry increased by 6.0% from the previous year, and the value added of the industry was 2.2 times higher than that of the manufacturing industry. From a long-term perspective, it is important to secure a global competitive advantage in order to sustain the export high value-added of the software industry. The obstacles to entry into the overseas market of small to medium enterprises are as follows: first, difficulty in product development and localization of marketing; second, lack of investment for overseas expansion; and finally, competitiveness of software technology. In particular, To overcome such obstacles, Korean small and medium sized software companies should increase the technical perfection and secure software export competitiveness. The paper presents a payment settlement framework enabling adaptive reuse and semiautomatic development of global payment settlement services. The quantitative and qualitative evaluation results are presented with domestic and overseas case studies as follows: Firstly, semi-automatic development is realized successfully by applying the framework. Secondly, it is possible to maintain consistent quality of software and to deliver maintenance services without relying on the internal human resources. Thirdly, it is possible to reduce the project duration of the same development cope to less than 50% by applying the framework. Finally, because it is based on BPMN 2.0, which is a high level design diagram, it is expected that it will be easy to implement through components connection and reduce difficulties in technology transfer and localization. Also, at the time of runtime operation, it will be effective to understand the design idea easily and to carry out additional developments without human resource who participated in the initial project.

• Journal of the Korea Convergence Society
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• v.8 no.3
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• pp.191-197
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• 2017

This development is for non-destructive machine using X-Ray source about detecting outline faults of below middle size products. The differentiation is product of research and development unspecialized small and medium-sized products using X-Ray light sources can check real time if the surface of an external fault of radiation dose reference, within the leakage. The speed control is possible by software solution. In addition, we're working on possibly block doors for worker safety and equipment at the same time that inner drive can be identified in the image. These principles, as a key enabler of the current inspection system such as the container is small to medium-sized parts - a long way from utilization level is possible. This research will give rise to major effects for other various non-destructive market industries except car-industry. The most important fact is that this developed non-destructive machine is controlled below $0.2micro-S{\mu}v$.

• Child Health Nursing Research
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• v.8 no.4
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• pp.365-380
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• 2002

This study was to develop and evaluate injury prevention education proposal which will helpful and can be utilized directly on the first line spot for elementary school children. Education proposal development and evaluation process was 1) Construction of 10-times education proposal contents proper to schooler 2) Testify validity through 3 pediatric nursing professor and 4 elementary school nurse 3) Pretest was done from March, 2002 to July on 3-6th grade 313 elementary school students 4) Through correction and revision after pretest evaluation meeting, final injury prevention education proposal was developed 5) After 10-times injury education, evaluation was carried out about the degree of help in education contents and general constitution of injury education to total subjects of educated children. Injury prevention education proposal consists of 10 times and each subjects are followings. 1st is 「introduction of injury prevention education and the importance of injury prevention」 2nd is「safety in and around home」, 3rd is 「injury prevention in school」, 4th is 「prevention of violence」, 5th is 「motor vehicle safety」, 6th is 「water safety」, 7th is 「prevention of fire and burns」, 8th is 「toy and product safety」, 9th is 「sports and recretional activities safety」and the final 10th is 「injury prevention caused by animals」. In the evaluation, the degree of help in education contents showed it helped to children averaged 1.66 and general constitution showed averaged 2.17 that children satisfied about developed injury prevention proposal. This study expected to provide systematic and concrete guidance in injury prevention education for elementary school children.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.29 no.3
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• pp.181-185
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• 2016

One of the important issues for fabricating the microelectronic display devices such as FED, PDP, and VFD is to obtain a high vacuum level inside the panel. In addition, sustaining the initial high vacuum level permanently is also very important. In the conventional packing technology using a tabulation method, it is not possible to obtain a satisfiable vacuum level for a proper operation. In case of FED, the poor vacuum level results in the increase of operating voltage for electron emission from field emitter tips and an arcing problem, resultantly shortening a life time. Furthermore, the reduction of a sealing process time in the PDP production is very important in respect of commercial product. The most probable method for obtaining the initial high vacuum level inside the space with such a miniature and complex geometry is a vacuum in-line sealing which seals two glass plates within a high vacuum chamber. The critical solution for the vacuum sealing is to develop a frit glass to avoid the bubbling or crack problems during the sealing process at high temperature of about $400^{\circ}C$ under the vacuum environment. In this study, the suitable frit power was developed using a mixture of vitreous and crystalline type frit powders, and a vacuum sealed CNT FED with 2 inch diagonal size was fabricated and successfully operated.