• 제목/요약/키워드: Product Line

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와송약침액(瓦松藥鍼液)이 신장세포(腎臟細胞)에서 H2O2에 의한 세포사망(細胞死亡) 및 DNA 손상(損傷)에 미치는 영향(影響) (The Effects of Orostachys Japonicus A. Berger Aquacupuncture on Cell Death and DNA Damage Induced by H2O2 in Renal Tubular Cell)

  • 박상원;송춘호
    • Journal of Acupuncture Research
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    • 제18권1호
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    • pp.88-99
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    • 2001
  • Objectives : This study was performed to determine if Orostachys japonicus A. Berger aquacupuncture (OjB) provides the protective effect against the loss of celi viability and DNA damage induced by oxidant in renal proximal tubular cells. Methods : The cell viability was evaluated by a MTT reduction assay and DNA damage was estimated by measuring double stranded DNA breaks in opossum kidney (OK) cells, an established proximal tubular cell line. Lipid peroxidation was determined by measuring malondialdehyde (MDA), a product of lipid peroxidation. Results : $H_2O_2$ increased the loss of cell viability in a time-dependent manner, which were prevented by 0.1% OjB. The protective effect of OjB was dose-dependent over concentration range of 0.05-0.5%. $H_2O_2$ caused ATP depletion and DNA damage, which were prevented by OjB and the hydrogen peroxide scavenger catalase. The loss of cell viability by $H_2O_2$ was not affected by the antioxidant DPPD, but lipid peroxidation by the oxidant was completely inhibited by DPPD. Conclusions : These data suggest that $H_2O_2$-induced death results from a lipid peroxidation-independent mechanism and the protective effect of OjB is not associated with its antioxidant activity.

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교통분야의 리빙랩 적용사례 연구 : 보행자 자동감지 횡단보도 시스템을 중심으로 (A study on the Application of Living Lab in Transportation : Focused on the Auto-Image Sensing Signal System for Pedestrian)

  • 전나영;김수재;추상호;이향숙
    • 한국ITS학회 논문지
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    • 제17권2호
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    • pp.1-17
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    • 2018
  • 리빙랩이란 사용자가 직접 나서서 문제를 해결해 나가는 사용자 참여형 혁신 공간을 의미하며, 리빙랩 참여자는 기술 구상부터 제품 개발의 모든 과정에 참여할 수 있다는 특징이 있다. 본 연구에서는 보행자의 교통사고를 줄이기 위해 전주시를 대상으로 리빙래 방법을 이용하여 보행자 자동감지 횡단보도 시스템을 개발하였다. 또한 리빙랩 적용에 따른 시스템 효과를 분석하기 위해 보행자 대기시간, 보행자 및 차량 신호위반, 무단횡단 측면의 측정지표를 설정하였으며, 시스템 설치전, 설치후, 리빙랩 적용후의 세가지 단계별로 나누어 분석하였다. 측정지표 분석결과, 리빙랩을 적용한 시스템의 효과가 설치전과 설치후 보다 상대적으로 개선되는 것으로 나타났다. 본 연구는 국내 교통 분야에서 리빙랩이 적용된 첫 사례라는 점에서 의의가 있다.

Investigation of Al-Ni Alloys Deposition during Over-discharge Reaction of Na-NiCl2 Battery

  • Kim, Jeongsoo;Jo, Seung Hwan;Park, Dae-In;Bhavaraju, Sai;Kang, Sang Ook
    • 전기화학회지
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    • 제19권3호
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    • pp.57-62
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    • 2016
  • The over-discharging phenomena in sodium-nickel chloride batteries were investigated in relation to decomposition of molten salt electrolyte and consequent metal co-deposition. From XRD analysis, the material deposited on graphite cathode current collector was revealed to be by-product of molten salt electrolyte decomposition. In particular, the result showed that the Ni-Al alloys ($Al_3Ni_2$, $Ni_3Al$ and $Al_3Ni$) were electrochemically deposited on graphite current collectors in line with over-discharging behaviors. It is assumed that the $NiCl_2$ solubility in molten salt electrolytes leads to the co-deposition of Ni-Al alloys by increasing metal deposition potential above 1.6 V (vs. $Na/Na^+$). The cell tests have revealed that the composition of molten salt electrolytes modified by various additives makes a decisive influence on the over-discharging behaviors of the cells. It was revealed that NaOCN addition to molten salt electrolytes was advantageous to suppress over-discharge reactions by modifying the characteristics of molten salt electrolytes. NaOCN addition into molten salt electrolytes seems to suppress Ni solubility by maintaining basic melts. The cell using modified molten salt electrolyte with NaOCN (Cell D) showed relatively less cell degradation compared with other cells for long cycles.

농촌형 가정기업의 웹사이트 관리실태와 활성화를 위한 제언 (Web-site Management and Utilization Strategies for Family Farm Businesses)

  • 고선강;진경아
    • 가족자원경영과 정책
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    • 제9권1호
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    • pp.131-146
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    • 2005
  • The farming type in Korea is predominantly a small farm managed by family members. This study mainly examines the current usage of the website of family farms as a management tool for small farm business and discusses the strategies for effective utilization of the website. A county that currently employs governmental project of information system was purposely selected. Among all the websites operated by small farm businesses in that county, websites of which purpose is introduction of the business, advertisement, or e-business were included for analysis; it yielded total seven websites, The study was conducted with two phases; on-line website analysis and interview with business owners. The websites were analyzed based on four categories; content, interface, design, and site management. With regard to the content of the websites, the lack of connection between domain names and product names was found. Moreover, the problem relevant to site management was shown as low utilization of bulletin boards and delayed upload of new information. However, design and interface were comparatively well presented. Business owners reported that the motivation to initiate the websites was mostly supports from the governmental project for the agricultural information system. The barriers to effective management of websites were found i) business owner's misinterpretation of business website with e-business ii) very limited opportunity for website management education in small farm business, and iii) lack of regional infrastructure for information system. Based on the findings, this study suggests as followed; i) construction of infrastructure should be preceded to make effective management for websites; ii) education for website management should include small business management strategies as well as computer skills, iii) the education should be provided in diverse ways considering subject's characteristics iv) small farm business owners should be informed that their websites could play a role only to provide information about the products and hand over the practical load for e-business to retailing web sites such as portal shopping mall; and v) wives' participation should be encouraged.

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체험적 패션 매장에서 체험 요인이 점포만족도와 점포충성도에 미치는 영향 연구 - 시각적 자극물을 통한 가상 체험을 중심으로 - (The Effects of Experience Factors have on Store Satisfaction and Store Loyalty for Experimental Fashion Stores - Focusing on Virtual Experience by Visual Stimuli -)

  • 채희주;김민영;고은주
    • 복식
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    • 제66권4호
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    • pp.1-17
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    • 2016
  • Fashion stores have to change to fit such the taste of individual customers taste and try to give unique experiences to the customers. They need to develop a special space that entertains customers, and entices them to visit and revitalize the off-line stores. This paper aims to analyze the experimental factors of stores, and how each of the factors impact customer experience in order to find out its effect on store satisfaction and store loyalty. Data was analyzed by using SPSS 18.0 and AMOS 18.0. Results of this study are as follows. First, Visual, Tactile, and Gustatory are the main senses that influence the emotional experience of the customers on a store visit. Second, three factors that influenced customer experience in experimental fashion stores are 'Causing Interest', 'Causing Concern', and 'Causing Relationship.' Third, the 'Causing Interest' factor and the 'Causing Concern' factor showed positive correlation with store satisfaction, while the 'Causing Relationship' factor did not impact store satisfaction, which affected store loyalty. Fourth, each experimental fashion stores can have different effect to consumer satisfaction and loyalty. Also, fashion store brands without an experimental store can cause various effects to consumers when a flagship store with an array of product information is formed. The conclusion drawn from this study will provide a guideline for fashion stores attract faithful customers by improving their store environment.

LVDT센서를 이용한 접촉식 두께자동측정기 개발 (Development of Contact-Type Thickness Measurement Machine using LVDT Sensors)

  • 신기열;황선
    • 한국기계가공학회지
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    • 제14권4호
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    • pp.151-159
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    • 2015
  • In this study, we developed an automated contact-type thickness measurement machine that continuously and precisely measures the thickness of a PCB module product using multi-LVDT sensors. The system contains a measurement part to automatically measure the thickness in real time according to the set conditions with an alignment supply unit and unloading unit to separate OK and NG products. The sensors were calibrated before assembly in the measuring machine, and precision and accuracy performance tests were also performed to reduce uncertainty errors in the measurement machine. In the calibration test, the precision errors of the LVDT sensor were determined to be $1-3{\mu}m$ as 0.1% at the measuring range. A measurement error of 0.8 mm and 1.0 mm thickness test standards were found to be $1{\mu}m$ and $4{\mu}m$, and the standard deviations of two 1.0 mm products were measured as $14{\mu}m$ and $8{\mu}m$, respectively. In the measurement system analysis, the accuracies of test PCB standards were found to be $2{\mu}m$ and $3{\mu}m$, respectively. From the results of gage repeatability and reproducibility (R & R) crossed, we found that the machine is suitable for the measurement and process control in the mass production line as 7.92% of total gage R & R and in seven distinct categories. The maximum operating speed was limited at 13 pcs/min, showing a value good enough to measure.

이기종 멀티 셀 유연생산환경에서의 실시간 통합운용을 위한 공정관리 체계 (Process Management Systems for Integrated Real-Time Shop Operations in Heterogeneous Multi-Cell Based Flexible Manufacturing Environment)

  • 윤주성;남성호;백재용;권기억;이동호;이석우
    • 한국생산제조학회지
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    • 제22권2호
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    • pp.281-286
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    • 2013
  • As the product lifecycle is getting shorter and various models should be released to respond to the needs of customers and markets, automation-based flexible production line has been recognized as the core competitiveness. According to these trends, system vendors supply cell-level systems such as FMC(Flexible Manufacturing Cell) that is integration of core functions of FMS(Flexible Manufacturing System) and RMC(Reconfigurable Manufacturing Cell) that can easily extend components of FMC. In the cell-based environment, flexible management for shop floor composed of existing job shop, FMCs and RMCs from various system vendors has emerged as an important issue. However, there could be some problems on integrated operation between heterogeneous cells to use vendor-specific cell controllers and on seamless information flow with high level systems such as ERP(Enterprise Resource Planning). In this context, this paper proposes process management systems supporting integrated shop operation of heterogeneous multi-cell based flexible manufacturing environment: First of all, (1) Integrated Shop Operation System to apply the process management system is introduced, and (2) Multi-Layer BOP(Bill-Of-Process) model, a backbone of the process management system, is derived with its data structure. Finally, application of the proposed model is illustrated through system implementation results.

Is Mammography for Breast Cancer Screening Cost-Effective in Both Western and Asian Countries?: Results of a Systematic Review

  • Yoo, Ki-Bong;Kwon, Jeoung A;Cho, Eun;Kang, Moon Hae;Nam, Jung-Mo;Choi, Kui Son;Kim, Eun Kyung;Choi, Yun Jeong;Park, Eun-Cheol
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권7호
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    • pp.4141-4149
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    • 2013
  • Background: Mammography is considered the gold standard of breast cancer mass screening and many countries have implemented this as an established breast cancer screening strategy. However, although the incidence of breast cancer and racial characteristics are different between Western and Asian countries, many Asian countries adopted mammography for mass screening. Therefore, the objective of this research was to determine whether mammography mass screening is cost-effective for both Western and Asian countries. Materials and Methods: A systematic review was performed of 17 national mammography cost-effectiveness data sets. Per capita gross domestic product (GDP), breast cancer incidence rate, and the most optimal cost-effectiveness results [cost per life year saved (LYS)] of a mammography screening strategy for each data set were extracted. The CE/per capita GDP ratio is used to compare the cost-effectiveness of mammography by countries. Non-parametric regression was used to find a cut-off point which indicated the breast cancer incidence rate boundary line determining whether mammography screening is cost-effective or not. Results: We found that the cost-effective cut-off point of breast cancer incidence rate was 45.04; it exactly divided countries into Western and Asian countries (p<0.0014). Conclusions: Mammography screening is cost-effective in most of Western countries, but not in Asian countries. The reason for this result may be the issues of incidence rate or racial characteristics, such as dense breast tissue. The results indicate that mammography screening should be adopted prudently in Asian countries and other countries with low incidence rates.

소성 가공 해석을 통한 티타늄 합금 볼트 열간 단조 공정 분석 (Titanium alloy bolt hot forging process analysis through plastic working analysis)

  • 최두선;김태민;항봉석;한유진;고강호;박정래;박규백;이정우;김도언
    • Design & Manufacturing
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    • 제14권1호
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    • pp.42-48
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    • 2020
  • Titanium alloy has been in the spotlight as a core material in high-tech industries that require high strength and light weight because it has excellent strength and corrosion resistance and strength is higher than that of steel. Therefore, in various industries, existing steel products are intended to be replaced with titanium alloys. Titanium alloys can cause cutting tool breakage during cutting, and heat generated during cutting does not dissipate, accumulates in tools and workpieces, resulting in large wear and tear on thin workpieces. In addition, since titanium alloy is a metal with high chemical activity, the wear of the tool becomes more severe when the cutting speed is high, so machining of titanium bolt through cutting is very disadvantageous in terms of productivity. Therefore, the production of bolts using titanium alloys is being produced through a forging process to improve productivity and product quality. In this paper, hot forging molding analysis was performed on bolts used for fastening automobile parts using Ti-6Al-4V alloy, which is the most commonly used titanium alloy.

공구날 특이길이의 물리적 적합성 고찰 (Physically Compatible Characteristic Length of Cutting Edge Geometry)

  • 안일혁;김익현;황지홍
    • 한국정밀공학회지
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    • 제29권3호
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    • pp.279-288
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    • 2012
  • The material removal mechanism in machining is significantly affected by the cutting edge geometry. Its effect becomes even more substantial when the depth of cut is relatively small as compared to the characteristic length which represents the shape and size of the cutting edge. Conventionally, radius or focal length has been employed as the characteristic length with the assumption that the shape of cutting edge is round or parabolic. However, in reality, there could be various ways to determine the radius or focal length even for the same tool edge profile, depending on the region to be considered as cutting edge in the measured profile and the constraints to be set in constructing the best fitted circle or parabola. In this regard, the present study proposes various models to determine the characteristic length in terms of radius or focal length. Their physical compatibility are validated by carrying out 2D orthogonal cutting experiments using inserts with a wide range of characteristic length ($30{\sim}180\;{\mu}m$ in terms of radius) and then by investigating the correlation between the characteristic length and the cutting forces. Such validation is based on the common belief that the larger the characteristic length is, the blunter the cutting edge is and the higher the cutting forces are. Interestingly, the results showed that the correlation is higher for the radius or focal length obtained with a constraint that the center of best fitted circle or the focus of the best fitted parabola should be on the bisectional line of the wedge angle of tool.