• Asian Pacific Journal of Cancer Prevention
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• 제15권10호
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• pp.4147-4152
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• 2014

Standard therapy for advanced head and neck cancer consists of a combination of surgery and radiation. However, survival of this patient population has not improved during the past 20 years. Many different multimodality treatment schedules have been proposed, and chemotherapy is often used with the intent of organ preservation. The present study was intended to establish the efficacy of concomitant chemoradiation with a single agent carboplatin in advanced head and neck cancers.The objectives were to investigate the feasibility of concomitant administration of carboplatin, monitor acute toxicity during radiotherapy, and determine subacute side effects, such as wound healing following surgery after chemoradiotherapy. A prospective study was conducted wherein a total of 40 patients with stage III and IV squamous cell carcinomas of oral cavity, oropharynx, hypopharynx and larynx were enrolled. All patients were treated with external beam radiotherapy and weekly carboplatin area under curve (AUC of 5). Radiotherapy was given in single daily fractions of 1.8-2 grays (Gy) to a total dose of 66-72 Gy. Salvage surgery was performed for any residual or recurrent locoregional disease. Neck dissection was recommended for all patients with neck disease showing less than a complete response after chemoradiation. A total of 40 patients were enrolled of whom 32 were males and 8 were females. Highest incidence of cancer was seen in the 5th-6th decades of life with a median age of 47.7 years. Oropharyngeal tumours constituted a maximum of 21 patients followed by hypopharynx in 10, larynx in 7 and oral cavity in 2. 80% of the patients had a neck node on presentation of which 40% had N2-N3 nodal status. TNM staging revealed that 58% of patients were in stage III and 43% in stage IV. Evaluation of acute toxicity revealed that 50% had grade II mucositis, 25% grade III mucositis, 2.5% grade IV mucositis. 50% of patients had grade I skin reactions, 65% of patients had grade I thrombocytopenia, and 24% of patients had grade I anaemia. After completion of treatment 65% of patients had complete response at the primary and regional sites, and 35% of patients had a partial response of whom 23% underwent neck dissection and 5% of them underwent salvage surgery at the primary site. At the end of one year there were six deaths and four recurrences and 70% were free of disease. Concurrent chemoradiation with carboplatin provided good locoregional control for locally advanced head and neck cancers. This regimen, although toxic, is tolerable with appropriate supportive intervention. Primary site conservation is possible in many patients. Chemoradiotherapy appears to have an emerging role in the primary management of head and neck cancers.

• 한국항만경제학회지
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• 제29권2호
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• pp.173-194
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• 2013

본 논문의 목적은 해양클러스터를 구축하기 위한 정책방안을 제시하여 우리나라 항만의 글로벌 경쟁력 향상을 도모하고 정책적 제안을 통해 국가경제발전을 위한 국가경영의 적용에 있다. 이 연구의 기여는 우리나라가 세계적인 SPLC를 조성하여 국가경영차원의 SPL 정책개발을 통해 궁극적으로 국가경제발전에 이바지함에 있다. 연구방법론은 HFP, KJ, SWOT 방법론, 기술적 연역법으로 구성된 통합적 접근법이다. SPLC의 전략적 방안은 공간적집적화, ICT집적화, ICT교류 및 ET기회확대, DT/ICT서비스 통합화, SPL의 통합서비스제공 및 조직적인 정책을 이행하는 것이다. SPLC의 전략적 구축방안을 구체적으로 이행하기 위해서는 추진 주체의 선정이 필요하다. 이를 위해서는 민 관 학 연의 민관공동기구의 설립이 가장 바람직하다고 판단되며, 실무상 국가 경영차원의 조직적 정책지원방안의 추진이 수반되어야 한다. 본 연구를 강화하기 위해서는 고부가가치의 블루오션분야 개발관점에서 해양클러스터를 동반한 오프쇼어 부문의 보완 전향적인 연구가 필요하다.

• 디지털융복합연구
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• 제16권6호
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• pp.449-462
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• 2018

이 연구는 스포츠산업 분야 인재인 스포츠마케터 양성을 위한 역량기반 융합형 교육과정을 개발하는데 있다. 이를 위해 문헌조사, 심층인터뷰 및 직무분석을 실시하여 스포츠마케터가 되기 위한 필요 역량을 도출하고 역량 프로파일을 작성한 다음 전문가 검증을 거쳐 역량모델을 개발하였다. 스포츠마케터 역량모델은 경력유형별로 스포츠마케팅/PR과 스포츠이벤트로 구분하였으며 공통기본역량은 스포츠마인드 등 6개, 전문역량은 스포츠스폰서십 등 12개로 나타났다. 역량모델을 기반으로 개발된 스포츠마케터 교육과정은 스포츠산업의 이해, 스포츠마케팅커뮤니케이션, 스포츠관련 법률, 스포츠시설의 이해, 스포츠시설의 경영, 스포츠스폰서십, 스포츠미디어, 스포츠라이선싱, 스포츠에이전트, 이벤트 기획, 이벤트 운영, 제안서 작성법, 스포츠이벤트 현장실습으로 구성되었다. 개발된 스포츠마케터 양성 교육과정은 스포츠산업 관련 대학, 민간교육 기관에 활용되어 스포츠산업 인재 양성 및 보급에 기여할 것이다.

• 한국건설관리학회논문집
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• 제19권2호
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• pp.38-49
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• 2018

파리협약 비준 이후 온실감축에 대한 중요성 및 국가 의무가 커짐에 따라 정부에서는 건축산업의 온실가스 감축을 위한 정책을 지속적으로 강화해 나가고 있으며, 특히 노후건축물에 대한 에너지 성능개선의 필요성을 강조하고 있다. 2014년 이후 정부에서는 공공 노후건축물 그린리모델링 사업의 시공비 지원 등으로 시범사업을 운영 중에 있으며 이를 통해 그린리모델링의 모범사례를 개발하여 민간에 그린리모델링을 활성 시키고자 한다. 본 연구에서는 공공 노후건축물의 그린리모델링을 통한 수준별 경제성을 분석하였으며, 해당건물의 대안을 계획하기 위해 건물 육안조사 및 장비측정을 수행하였다. 개선안은 대안을 종합한 그린리모델링 계획안으로 수준별 5개의 개선안을 개발하여 각 안에 대한 경제성을 분석하였다. 분석방법은 ECO2를 통한 1차 에너지소요량 산정 및 LCC 분석을 진행하였으며, LCC 측면에서는 개선 3, 4안(중간수준 안)이 가장 우수한 것으로 분석되었으며, 다음으로 최대비용안, 최소 비용 안 순으로 결과가 도출되었다. 이 결과로 향후 진행될 그린리모델링 성능계획 및 경제성 분석 시 기초자료로서 활용이 가능 할 것으로 예상된다.

• 한국언론정보학보
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• 제43권
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• pp.7-46
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• 2008

이 글의 목적은 문화연구와 정치경제학을 중심으로 한국의 비판언론학을 성찰하고 미래의 방향을 제시보고자 하는 데 있다. 1980년대 중후반부터 나타나기 시작한 문화연구의 '소비로의 전환'은 문화연구를 신수정주의로 부르게 만든 결정적인 요소의 하나지만, 한국에서는 비판적 문제의식의 단절로 읽혀져 문화연구에 대한 끊임없는 정체성 논란을 불러일으켰다. 그러나 정작 정치경제학은 자신이 중시하는 생산(과정)/구조에 대해서도 많은 연구를 내지 못했고, 문화연구 역시 이 부문에서는 무관심으로 대응했다. 국면주의는 문화연구가 현실에 개입하는 유력한 방식이지만 초기의 연구 외에는 후속연구가 그다지 활발하지 못해 이론화 수준이 높지 않고, 한국에서의 연구 또한 아직은 많은 논란을 안고 있어 성과 여부가 불투명하다. 비판연구가 가진 저항성의 문제는 운동론에서 두드러지는데, 이 글에서는 문화연구의 특징이 잘 배어 있는 소수자문화운동론에 대한 검토를 통해 사회적 배치의 여전한 중요성을 강조했다. 미래의 방향에서는 일부 논자들이 제안한 바 있는 문화연구와 정치경제학의 화합 가능성을 긍정적으로 검토했고, 이의 근저에 있는 근대주의/탈근대주의 합의의 가능성과 필요성 역시 차이를 인정하면서도 결합의 가능성도 놓치지 않는 '복합적 합의'를 하나의 대안으로 제시했다. 마지막으로 '시공간의 재조직', '소비자본주의', '문화적 시민권'(또는 '문화적 공론장'), '생산문화', '시민/소비자', '차별화/차이', '공영방송의 미래' 등을 양측이 서로 경(결)합할 수 있는 공감대가 큰 연구주제로 꼽았다.

• The Journal of Advanced Prosthodontics
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• 제10권2호
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• pp.113-121
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• 2018

PURPOSE. The aim of this preliminary study was to investigate, for the first time, the effects of addition of titania nanotubes ($n-TiO_2$) to poly methyl methacrylate (PMMA) on mechanical properties of PMMA denture base. MATERIALS AND METHODS. $TiO_2$ nanotubes were prepared using alkaline hydrothermal process. Obtained nanotubes were assessed using FESEM-EDX, XRD, and FT-IR. For 3 experiments of this study (fracture toughness, three-point bending flexural strength, and Vickers microhardness), 135 specimens were prepared according to ISO 20795-1:2013 (n of each experiment=45). For each experiment, PMMA was mixed with 0% (control), 2.5 wt%, and 5 wt% nanotubes. From each $TiO_2$:PMMA ratio, 15 specimens were fabricated for each experiment. Effects of $n-TiO_2$ addition on 3 mechanical properties were assessed using Pearson, ANOVA, and Tukey tests. RESULTS. SEM images of $n-TiO_2$ exhibited the presence of elongated tubular structures. The XRD pattern of synthesized $n-TiO_2$ represented the anatase crystal phase of $TiO_2$. Moderate to very strong significant positive correlations were observed between the concentration of $n-TiO_2$ and each of the 3 physicomechanical properties of PMMA (Pearson's P value ${\leq}.001$, correlation coefficient ranging between 0.5 and 0.9). Flexural strength and hardness values of specimens modified with both 2.5 and 5 wt% $n-TiO_2$ were significantly higher than those of control ($P{\leq}.001$). Fracture toughness of samples reinforced with 5 wt% $n-TiO_2$ (but not those of 2.5% $n-TiO_2$) was higher than control (P=.002). CONCLUSION. Titania nanotubes were successfully introduced for the first time as a means of enhancing the hardness, flexural strength, and fracture toughness of denture base PMMA.

• 대한소아치과학회지
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• 제47권1호
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• pp.44-52
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• 2020

1956년 한국에 처음 소아치과학교실이 창설되었고, 1992년 한국 최초의 소아전문 치과의원이 등장하였다. 치의학의 발전과 소아치과에 대한 대중의 인식 변화로 인해 소아전문 치과의원은 점점 더 증가하고 있다. 이 연구의 목적은 지역 분포를 포함한 여러 측면에서 한국의 소아전문 치과의원의 현황을 조사하는 것이다. 한국에 17,917개의 치과의원 중 소아전문 치과의원은 343개이고, 1.91%를 차지하였다. 343명의 소아전문 치과의원 개원의 중 248명이 소아치과 전문의였다. 소아치과 전문의 248명 중 25명이 전문의를 표방하여 개원하고 있었다. 16개의 시도 중 경기도에 소아전문 치과의원이 가장 많았고, 33.5%를 차지하였다. 서울과 부산이 그 뒤를 이었다. 서울의 25개 구 중에서는 강남구에 소아전문 치과의원이 가장 많았고, 유소년 10만명당 소아전문 치과의원 수도 강남구에서 제일 높았다. 소아전문 치과의원의 90.9%는 평일 야간진료를 하지 않았고, 26.5%는 토요일에 15시 이후에 문을 닫았다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6059-6062
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• 2012

Regional cancer epidemiology is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the pattern of head and neck cancer in western Nepal and hence an attempt was here made to evaluate the situation based on hospital data, which provide the only source in the western region of Nepal. A clinicopathological analysis of head and neck cancers treated between 2003 and 2006 in Manipal Teaching Hospital affiliated to Manipal College of Medical Sciences, Pokhara, Western Development Region, Nepal was performed. A total of 105 head and neck cancer cases were identified with a male to female ratio of 1.8:1. The median ages of male and female patients were 62 and 64 years, respectively. Ninety-seven (92.4%) of the cancer patients were suffering from carcinoma, three (2.9%) had blastoma, three (2.9%) had sarcoma, and two (1.9%) had lymphoma. The majority (61.9%) of carcinoma cases were squamous cell carcinoma followed by anaplastic carcinoma (7.2%). Of the carcinoma cases, the most common site of primary lesion was larynx (19.6%), followed by the thyroid (14.4%), the tongue and hypopharynx with 10.3% cases each. Comparative analysis among males and females did not reveal any sex difference in type of head and neck cancers. The head and neck cancer pattern revealed by the present study provides valuable leads to cancer epidemiology in western Nepal and useful information for health planning and cancer control, and future research in western Nepal.

• 기술경영경제학회:학술대회논문집
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• 기술경영경제학회 1998년도 제13회 하계학술발표회 논문집
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• pp.131-163
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• 1998

The interest in the evaluation of government-sponsored research institutes (GRIs) has increased markedly in Korea in 1990s; this is mainly because of the increasing needs 1) to improve the quality of R&D at GRIs, and 2) to reorient the GRIs' strategic position in Korean national innovation systems due to the enhancement of R&D capabilities of private companies and universities during last decade. As a first attempt to diagnose the managerial and strategic issues of GRIs, a Multi-Ministerial Evaluation Committee was established as an ad hoc task force under the Prime Minister's Office in 1991. According to the recommendations of the committee, the Ministry of Science and Technology (MOST) to which most of GRIs were affiliated, made it a rule to evaluate the annual performance of GRIs since 1992. This paper examines the recent experience of MOST's evaluation of Government-sponsored Research Institute in Korea. After several years'efforts of Science & Technology Policy Institute(STEPI) to build prospective evaluation systenL MOST decided to apply two supplementary approaches for the evaluation of GRIs; one is summative annual evaluation and the other is formative 3-year evaluation. The annual evaluation system that is designed as a temporary measure is to monitor and to guide the self-evaluation activities of GRIs. In the process of annual evaluation, MOST tries to minimize its direct involvement, and allows each GRI to develop self-evaluation system that is most appropriate for the unique characteristics of the institute. If there exist urgent issues under scrutiny, however, it can be incorporated and examined by a group of external experts as special issues in the annual evaluation system. The aim of 3-year evaluation is both to examine the past performance of each GRI and to investigate whether the strategic role of each GRI is viable in the future. Its major focus, however, lies not on auditing past performance but on strengthening future strategic position of each GRI. The MOST designates a group of evaluation experts with appropriate knowledge and competence as members of the General Evaluation Committee for one year. With the help of STEPI, a specialized research institute for R&D evaluation, the General Evaluation Committee develops methodology and procedures for the actual evaluation of GRIs. Based on the evaluation reports and recommendations from the General Evaluation Committee, the MOST develops various policy measures for strengthening GRIs.

• 한국학교보건학회지
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• 제10권1호
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• pp.41-50
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• 1997

The purpose of this study is to provide fundamental data supporting facilitation of a formal health education performed by school nurses as health educators. To evaluate the teacher expertise of school nurses as health educators, this study analyzed the present status of health education and the recognition of self-confidence in teaching ability of school nurses. Self addressing questionnaire were mailed out to 340 secondary school nurses in Seoul and out of them 244 nurses (71.8%) responded to the survey. Analysis of the data was made using t-test and ANOVA in SAS program. The major results are as follows : 1. The total health instruction performance rate was 84.6% (204). Regular health instruction was carried out by 66 nurses and the rest of the 155 subjects gave irregular instruction on health education. 2. Regular health education classes was offered as a part of physical education class hour by 89.4% of the respondents whereas only 10.6% of them had formal health education classes. The survey showed that irregular health education classes were mainly held in physical education class hours (70.3%) and 14.8% had opportunities for additional classes on health education. 3. The average class for regular health education was 5 hours per week but for irregular health education classes were only one hour per semester (32.9%). 4. Among the 11 categories of health education, education on drug abuse and body structure and function and physical development occupied 95.6%, 69.6% respectably while physical training, family health, social health occupied 10.8%, 12.7%. 5. Health education was given much more at public schools (88.2%) than at private schools. 6. 232 (95.0%) school nurses agreed with the necessity of formalizing health education classes and 227 (93.1%) wanted to change their status from school nurses to formal health teachers. 7. There is a tendency to change the status from school nurse to formal health teacher, and the necessity of having a formal curriculum on health education while less recognized by the older and longer-careered nurses was more recognized by those nurses with higher education. 8. The lack of administrative support (79.5%), work burden (77.9%), and lack of teaching competency (22.1%) were the greatest problems. 9. Education on drug abuse was stressed the most whereas physical training was most neglected. 10. There is a tendency that older and longer-careered school nurses thought less positively of their status, and then 98 (81.1%) school nurses acknowledged themselves as professional teachers. 11. 176 (72.5%) school nurses agreed with the necessity of continuing education : health knowledge and teaching skills for formal health teachers. 12. 179 (73.8%) school nurses had a positive attitude and undergraduate preparation and the practice of professional health teachers. 13. The school nurses had self-confidence in their teaching competence, teaching strategies and knowledge in all 11 health education areas.