• The Korean Journal of Malacology
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• v.2 no.1
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• pp.1-9
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• 1986

The authors carried out paralytic shellfish poison bioassay on the 9 kinds of shellfishes collected from Pusan and Kyungnam areas of Korea from April to July, 1986. The areas are the main producing district of fisheries in Korea and the samples were collected from their producing sites-natural, cultured and marketed. There were little or no PSP in the majority of the shellfishes, but 3 natural (Pusan Il-Kwang $700{\mu}g$, Koje Okpo $648{\mu}g$, Chungmoo Madong $124{\mu}g/100gm$ meat) and 1 marketed (Pusan Chakalchi $490{\mu}g/100gm$ meat) blue mussels contained relatively high PSP only in April. It is considered that there will be a possibility of paralytic shellfish poisoning, and control program for preventing the poisoning is necessary in Korea.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.14 no.2
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• pp.78-87
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• 2018

Patients with mental disability who are classified as dental severely disabled, have poor oral health status and many difficulties in taking health services. The purpose of this study was to investigate factors of influencing in visiting oral health care services. After receiving approval from institutional review board in Seoul National University, 39 participants were recruited and the oral health examination and questionnaire were taken. Data were analyzed using one-way ANOVA, independent t-test, hierarchical linear regression for predicting influence of each participants' characteristics on oral examination time and care time. In regression model, the higher the disability grade and the lower the degree of cooperation, the more oral examination time increased. However possibility of communication was not significantly influenced. Also, the higher the disability grade and the lower the degree of cooperation, the more oral care time increased. However possibility of communication was not significantly influenced. These results are expected to provide objective data for introduction and establishment of visiting dental care.

• Journal of Preventive Medicine and Public Health
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• v.9 no.1
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• pp.87-94
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• 1976

In order to study the chelating action of d-penicillamine on lead and the possibility of its application to the provocation test for diagnosis of lead poisoning, urinary excretion of lead was measured from 24-hour urine samples before, during and after administration of d-penicillamine by oral route for 5 days on 18 lead workers. The results were as follows: 1. Oral d-penicillamine 600 mg/day raised the excretion of urinary lead by approximately 3 times as compared with initial urinary lead level. 2. Initial urinary lead level was the better indicator of urinary lead excretion in d-penicillamine administration than initial blood lead ${\delta}-ALA$ and hemoglobin level. 3. Oral d-penicillamine may be quite useful in provocation test for lead poisoning.

• Journal of Preventive Medicine and Public Health
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• v.52 no.5
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• pp.277-280
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• 2019

The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine ($Hantavax^{(R)}$) would change from 3 to 4. Some aspects of this decision remain controversial. Based on the characteristics of Hantaan virus (HTNV) and its role in the pathogenesis of hemorrhagic fever with renal syndrome, it might be difficult to develop an effective and safe HTNV vaccine through the isolate-inactivate-inject paradigm. With the development of high-through-put 'omics' technologies in the 21st century, vaccinomics has been introduced. While the goal of vaccinomics is to develop equations to describe and predict the immune response, it could also serve as a tool for developing new vaccine candidates and individualized approaches to vaccinology. Thus, the possibility of applying the innovative field of vaccinomics to develop a more effective and safer HTNV vaccine should be considered.

• Journal of the Korean Society of Food Culture
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• v.23 no.1
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• pp.68-72
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• 2008

This study demonstrated the effects of extracts from the mushroom Keumsa sangwhang(Phellinus linteus) (KPLE) on fasting glucose and cholesterol levels in human blood. In this double-blind, placebo-controlled human intervention study, healthy volunteers were randomized to receive 3.3 g of KPLE (n=31) or placebo (n=31) per day by oral administration for 8 weeks. The cholesterol and fasting serum glucose levels were evaluated before and after treatment. The fasting serum glucose level was significantly decreased by KPLE administration (p<0.01), but the total cholesterol, triglyceride, HDLcholesterol and LDL-cholesterol concentrations did not change. This study suggests a possibility that KPLE may be useful as a functional food for the prevention of diabetes mellitus.

• Korean Journal of Health Education and Promotion
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• v.33 no.5
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• pp.107-119
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• 2016

Objectives: This study aims at examining the association of sense of community with community participation for health promotion in urban areas of Korea. Methods: We analyzed data from 'Community Capacity for Healthy Gangdong Communites' Survey' in 2007. The survey was based on self-reported questionnaires, which were distributed to 1,800 community residents over the age of nineteen in five administrative communities of Gangdong-gu, Seoul, in Korea by using proportionate probability sampling method. We measured 'Sense of community' with four indicators including 'Good neighborhoods', 'Perceived possibility of cooperation', 'Pride of community' and 'Possibility of development' by using 5-point Likert scales. Community participation was measured with the experience rate or the extent of participation by 5-point Likert scales in seven community actions or activities including voting, community program planning, social actions, etc. We examined the association of sense of community with community participation by using regression analyses. Results: This study has shown that sense of community was associated with and made positive impacts on community participation in diverse community actions or activities in urban communities. Conclusions: For promoting community health in urban areas, we can increase community participation more effectively with the efforts of enhancing sense of community.

• The Journal of the Korean dental association
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• v.50 no.9
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• pp.558-565
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• 2012

Dental caries is multifactorial local disease which involves destruction of the hard tissues of the teeth by metabolities produces by microorganisms. Recently, there has been growing interest in the role of nitric oxide (NO) and glutathione (GSH) in caries incidence. The aim of the study was to survey the studies reported the association among salivary NO, GSH and dental careis. Three studies reported the association between NO and dental caries. However, the results were contradictory. Only one study showed negative association between GSH and dental caries. In Korea, NO showed negative association with Lactobacilli and GSH showed positive association with dental caries. These observations suggest the possibility that NO and GSH could be new biomarkers for dental caries. However, further study should be needed.

• Journal of Preventive Medicine and Public Health
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• v.6 no.1
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• pp.65-70
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• 1973

The study in the fild of medical instrument has been out of the interest by any of the life scientist in Korea. Especially, the recent developments in the medical electromics are remarkable one. Authors planned this study to ascertain the possibility of setting up the thermister thermometer with available accessories of demestic prouducts including some specific foreign assembly parts. By proper use of the thermister as one of the wheatstone bridge, we could detect tile resistance variations due to the environmental temperature variace. The intensive care for the bridge circuit and compensation scheme was required. The calibration procedure adopted here makes it possible to read the current as the temperature. The temperature range was determined by the examination and construction of the graph of the resistance-temperature variation. The determination of electric current, available ambient-temperature, the reduction of excessive current and self-heating of the thermister were made. Renovation in response-velocity was under taken too. This electronic thermometer was designed and assembled by the circuitry developed in accordance with the maximum availability of domestic products with some foreign-made parts. The result of our experiment showed very stable function and proved to be the most promissing item in the actual application as long as the thermistor thermister is concerned.

• The Korea Journal of Herbology
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• v.22 no.4
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• pp.247-252
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• 2007

Objectives : Fructus Amomi has been widely used to treat patients with anorexia and dyspepsia induced by moisture or cold. In addition, it is known to have preventive effects on miscarriage. But, this preventive effect of Fructus Amomi has controversial point. For this reason, this study was designed to investigate the preventive effects of Fructus Amomi on miscarriage in the framework of usage. Methods : We investigated the preventive effects of Fructus Amomi on miscarriage in terms of checking frequency in use of Fructus Amomi in Dongeui-bogam. Results : Fructus Amomi was used by 192 times in Dongeuh-bogam. it was used by 36 times in major drug, the others used in complementary drug. 14 remedies were used to treat patients with gynecologic diseases. In these remedies, 7 remedies were related to preventive effects of Fructus Amomi on miscarriage. In thses 7 remedies, 6 were used with samul-tang or Radix Scutellariae and Rizoma Atractylodis Macrocephalae. Conclusions : These results suggest the possibility that preventive effects of Fructus Amomi on miscarriage is not involved in direct efficacy, which was explained with gimi-ron, but in usage of the herbal medicine.

• Journal of Preventive Medicine and Public Health
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• v.45 no.3
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• pp.164-173
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• 2012

Objectives: Over the past several years, the incidence of hepatitis A infection has been increasing rapidly in the young-adult population in Korea. We examined the effects of area-level socioeconomic status and environmental hygiene on the incidence of hepatitis A. Methods: This study is based on the registered national population of Korea and the national health insurance data from 2004 to 2008. A total of 73 459 individuals were confirmed to have had hepatitis A. The standardized incidences of hepatitis A in 232 districts adjusted for sex and age of people were calculated for each year, and the rate ratios of the incidence rates were estimated according to area-level socioeconomic status and environmental hygiene using multiple Poisson regression models. Results: The incidence rates of hepatitis A infection were 15.6 (per 100 000) in 2004, 19.0 (per 100 000) in 2005, 27.2 (per 100 000) in 2006, 25.1 (per 100 000) in 2007, and 61.7 (per 100 000) in 2008. The analysis of the area-level effects showed that residential areas of the less deprived than other regions, areas with higher levels of education, and heavily populated areas were significantly associated with increased risk. Conclusions: There is a very strong possibility that both area-level socioeconomic status and environmental hygiene play a role in increasing the risk of hepatitis A infection in Korea. Therefore, to reduce hepatitis A infection, we need a nationwide strategy that considers these area-level characteristics.