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Effects of Extracts from the Mushroom Keumsa Sangwhang (Phellinus linteus) on Fasting Blood Glucose and Cholesterol Levels in Human

금사상황버섯 추출물 복용이 공복혈당 및 혈중지질농도에 미치는 효과

  • Kim, Yong-Dae (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Kim, Nam-Sik (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Eom, Sang-Yong (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Kim, Sung-Hoon (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Kang, Jong-Won (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Lee, Sang-Won (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Park, Soon-Young (Department of Preventive Medicine, College of Medicine, Kyung-Hee University) ;
  • Kim, Jeong-Su (Department of Nutrition Food and Exercise Sciences, The College of Human Sciences, Florida State University) ;
  • Kim, Heon (Department of Preventive Medicine, College of Medicine, Chungbuk National University) ;
  • Hong, Jang-Soo (Department of Thoracic Surgery, College of Medicine, Chungbuk National University)
  • 김용대 (충북대학교 의과대학 예방의학교실) ;
  • 김남식 (충북대학교 의과대학 예방의학교실) ;
  • 엄상용 (충북대학교 의과대학 예방의학교실) ;
  • 김성훈 (충북대학교 의과대학 예방의학교실) ;
  • 강종원 (충북대학교 의과대학 예방의학교실) ;
  • 이상원 (충북대학교 의과대학 예방의학교실) ;
  • 박순영 (경희대학교 의과대학 예방의학교실) ;
  • 김정수 (플로리다주립대 생명과학대학 영양식품운동과학과) ;
  • 김헌 (충북대학교 의과대학 예방의학교실) ;
  • 홍장수 (충북대학교 의과대학 흉부외과학교실)
  • Published : 2008.02.29

Abstract

This study demonstrated the effects of extracts from the mushroom Keumsa sangwhang(Phellinus linteus) (KPLE) on fasting glucose and cholesterol levels in human blood. In this double-blind, placebo-controlled human intervention study, healthy volunteers were randomized to receive 3.3 g of KPLE (n=31) or placebo (n=31) per day by oral administration for 8 weeks. The cholesterol and fasting serum glucose levels were evaluated before and after treatment. The fasting serum glucose level was significantly decreased by KPLE administration (p<0.01), but the total cholesterol, triglyceride, HDLcholesterol and LDL-cholesterol concentrations did not change. This study suggests a possibility that KPLE may be useful as a functional food for the prevention of diabetes mellitus.

Keywords

References

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