• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.5
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• pp.460-469
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• 2019

Purpose: The ${\beta}3-adrenergic$ receptor (ADRB3) is expressed in visceral adipose tissue and has been speculated to contribute to lipolysis, energy metabolism, and regulation of the metabolic rate. In this study, we aimed to investigate the association of polymorphism of the ADRB3 gene with the sex of children with obesity and related pathologies. Methods: ADRB3 gene trp64arg genotyping was conducted in 441 children aged 6-18 years. Among these subjects, 264 were obese (103 boys; 161 girls) and 179 were of normal weight (81 boys; 98 girls). In the obese group, fasting lipids, glucose and insulin levels, and blood pressure were measured. Metabolic syndrome (MS) was defined according to the modified World Health Organization criteria adapted for children. Results: The frequency of trp64arg genotype was similar in obese and normal weight children. In obese children, serum lipid, glucose, and insulin levels; homeostasis model assessment of insulin resistance (HOMA-IR) scores; and MS were not different between arg allele carriers (trp64arg) and noncarriers (trp64trp). In 264 obese children, genetic analysis results revealed that the arg allele carriers were significantly higher in girls than in boys (p=0.001). In the normal weight group, no statistically significant difference was found between genotypes of boys and girls (p=0.771). Conclusion: Trp64arg polymorphism of the ADRB3 gene was not associated with obesity and MS in Turkish children and adolescents. Although no relationships were observed between the genotypes and lipids, glucose/insulin levels, or HOMA-IR, the presence of trp64arg variant was frequent in obese girls, which can lead to weight gain as well as difficulty in losing weight in women.

• Journal of the Korean GEO-environmental Society
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• v.20 no.3
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• pp.39-46
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• 2019

The liquefaction is a phenomenon that the effective stress becomes zero due to the rapidly accumulated excess pore water pressure when a strong load acts on the ground for a short period of time, such as an earthquake or pile driving, resulting in the loss of the shear strength of the ground. Since the Geongju and Pohang earthquake, liquefaction brought increasing domestic attention. This liquefaction can be assessed mainly through the semi-empirical procedures proposed by Seed and Idriss (1982) and the liquefaction risk based on the penetration resistance obtained from borehole DB and SPT. However, the geotechnical information data obtained by the in-situ tests or boring information fundamentally have an issue of the representative of the target area. Therefore, this study sought to construct a ground information database by classifying and reviewing the ground information required for liquefaction assessment, and tried to solve the representative problem of the soil layer that is subject to liquefaction evaluation by performing spatial interpolation using GIS.

• Journal of Chest Surgery
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• v.54 no.3
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• pp.186-190
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• 2021

Background: Pre-lifting of the sternum marked a major turning point in pectus excavatum repair. The author developed the crane technique in 2002 and successfully applied it to more than 2,000 cases using sternal wire stitching. However, blind sternal suturing limited the use of the wire-stitch crane. We propose a novel screw for sternal lifting as a new tool for the crane technique. Methods: We developed a screw system strong enough to withstand the pressure needed for sternum lifting. The screw was designed to have a broader thread to hold the bony tissue securely. The screw's sustaining power was tested using the torsion, driving torque, and axial pull-out tests in a polyurethane block and ex-vivo porcine sternum. Results: The screws were easily driven into the sternum, and the head of the screw was connectable to the table-mounted retractor. In the torsion test, the 2° offset torsional yield was 4.53 N·m (reference value, 1 N·m). In the polyurethane block driving torque test, the maximum torque was 0.98 N·m (reference value, 0.70 N·m). The axial pull-out test was 446 N (reference value, 100 N). The maximum pull-out resistance in the ex-vivo porcine sternum model was 1,516 N. Conclusion: The screw crane was strong enough to sustain the chest wall weight to be lifted. Thus, the screws could effectively replace the sternal wire stitching in crane pre-lifting of the sternum. We expect that application of the screw-crane will be easy and that it will improve the safety and success rate of pectus repair surgery.

• Korean Journal of Materials Research
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• v.31 no.3
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• pp.150-155
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• 2021

Zinc oxide (ZnO) based transparent conducting oxides (TCO) thin films, are used in many applications such as solar cells, flat panel displays, and LEDs due to their wide bandgap nature and excellent electrical properties. In the present work, fluorine and aluminium-doped ZnO targets are prepared and thin films are deposited on soda-lime glass substrate using a RF magnetron sputtering unit. The aluminium concentration is fixed at 2 wt%, and the fluorine concentration is adjusted between 0 to 2.0 wt% with five different concentrations, namely, Al2ZnO98(AZO), F0.5AZO97.5(FAZO1), F1AZO97(FAZO2), F1.5AZO96.5(FAZO3), and F2AZO96(FAZO4). Thin films are deposited with an RF power of 40 W and working pressure of 5 m Torr at 270 ℃. The morphological analysis performed for the thin film reveals that surface roughness decreases in FAZO1 and FAZO2 samples when doped with a small amount of fluorine. Further, optical and electrical properties measured for FAZO1 sample show average optical transmissions of over 89 % in the visible region and 82.5 % in the infrared region, followed by low resistivity and sheet resistance of 3.59 × 10-4 Ωcm and 5.52 Ω/sq, respectively. In future, these thin films with excellent optoelectronic properties can be used for thin-film solar cell and other optoelectronics applications.

• Journal of the Korean Society of Safety
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• v.36 no.2
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• pp.10-17
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• 2021

This paper presents the robust design of each component used in the development of an induction bolt heating system for dismantling the high-temperature high-pressure casing heating bolts of turbines in power plants. The induction bolt heating system comprises seven assemblies, namely AC breaker, AC filter, inverter, transformer, work coil, cable, and CT/PT. For each of these assemblies, the various failure modes are identified by the failure mode and effects analysis (FMEA) method, and the causes and effects of these failure modes are presented. In addition, the risk priority numbers are deduced for the individual parts. To ensure robust design, the insulated-gate bipolar transistor (IGBT), switched-mode power supply (SMPS), C/T (adjusting current), capacitor, and coupling are selected. The IGBT is changed to a field-effect transistor (FET) to enhance the voltage applied to the induction heating system, and a dual-safety device is added to the SMPS. For C/T (adjusting current), the turns ratio is adjusted to ensure an appropriate amount of induced current. The capacitor is replaced by a product with heat resistance and durability; further, coupling with a water-resistant structure is improved such that the connecting parts are not easily destroyed. The ground connection is chosen for management priority.

• The Plant Pathology Journal
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• v.37 no.2
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• pp.152-161
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• 2021

Sugar beet (Beta vulgaris L.) is known as a key product for agriculture in several countries across the world. Beet soil-borne virus (BSBV) triggers substantial economic damages to sugar beet by reducing the quantity of the yield and quality of the beet sugars. We conducted the present study to report the complete genome sequences of two BSBV isolates in Turkey for the first time. The genome organization was identical to those previously established BSBV isolates. The tripartite genome of BSBV-TR1 and -TR3 comprised a 5,835-nucleotide (nt) RNA1, a 3,454-nt RNA2, and a 3,005-nt RNA3 segment. According to sequence identity analyses, Turkish isolates were most closely related to the BSBV isolate reported from Iran (97.83-98.77% nt identity). The BSBV isolates worldwide (n = 9) were phylogenetically classified into five (RNA-coat protein read through gene [CPRT], TGB1, and TGB2 segments), four (RNA-rep), or three (TGB3) lineages. In genetic analysis, the TGB3 revealed more genetic variability (Pi = 0.034) compared with other regions. Population selection analysis revealed that most of the codons were generally under negative selection or neutral evolution in the BSBV isolates studied. However, positive selection was detected at codon 135 in the TGB1, which could be an adaptation in order to facilitate the movement and overcome the host plant resistance genes. We expect that the information on genome properties and genetic variability of BSBV, particularly in TGB3, TGB1, and CPRT genes, assist in developing effective control measures in order to prevent severe losses and make amendments in management strategies.

• Journal of the Korea Convergence Society
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• v.13 no.3
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• pp.191-196
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• 2022

Unlike an international combustion engine car, a battery-powered electric vehicle requires an additional heat source for its heating system. A high-voltage coolant heater has the advantages of high efficiency and a wide operating temperature range. In its development, the geometry design of the coolant flow path is essential. This paper presents the thermal flow simulations of a 7kW high-voltage heater with symmetric serpentine flow channels arranged parallelly. The heater performance was evaluated from the simulation results in terms of the pressure and temperature differences and the flow uniformity. The proposed design showed a greater flow resistance and similar heat exchanging capability than the existing parallel serpentine design. It has the advantage of a relatively wide low-temperature surface area, where the control circuit board susceptible to high temperatures can be located.

• Journal of the Society of Disaster Information
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• v.18 no.1
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• pp.1-9
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• 2022

Purpose: In this study, we used hydrophilic waterstop used in geosynthetics vertical barrier system to evaluate the performance of impermeability under sealing conditions. Method: ASTM D5887 and ASTM D6766 were applied to determine the capability of the connection during the geosynthetics vertical barrier system. Hydrophilic waterstop was saturated in each solution and the weight, thickness, and volume changes were analyzed over elapsed time. Hydrophilic waterstop was installed at the geosynthetics vertical barrier system connection to evaluate the permeability characteristics. Results: As the expansion reaction time of hydrophilic waterstop increased relatively under saline conditions, the decrease in permeability also showed a smaller decrease in fresh water. Furthermore, the method of engagement of the geosynthetics vertical barrier system showed somewhat better performance of the impermeability due to the large pressure resistance caused by the roll joint type than interlock type. Conclusion: In urban pollutants, which can estimate the outflow of pollutants such as oil storage facilities and industrial complexes, proactive response technologies that can prevent the contaminant diffusion can significantly reduce the damage.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.5
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• pp.151-160
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• 2022

Owing to the recent increase in the frequency of explosion accidents, blast resistive design has garnered attention to reduce the damage of important structural elements. However, domestic research on the blast resistive structures is still insufficient, and domestic design guideline against blast loads are not documented yet. In this study, a numerical study on the RC blast resistive walls, where the test variable was the presence of FRP sheet, was performed using LS-DYNA program. Based on the numerical results, displacement-time hysteretic curve, pressure-impulse diagram, and fragility curve of the test specimens were derived. It was shown that the FRP sheet strengthening method is efficient to improve the blast resistive performance of the RC wall. Also, the strengthening effect of FRP sheet on the RC wall was stronger when the magnitude of the blast load was greater.

• Corrosion Science and Technology
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• v.20 no.6
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• pp.335-346
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• 2021

Since epoxy resin coating shows excellent properties in formability, adhesion, and corrosion resistance, they have been extensively used in many industries. However, various types of damages in the epoxy coated tube within a relative short time have been reported due to cavitation erosion, liquid impingement, variation of temperature and pressure. Nevertheless, there has been little research on the effect of temperature on the cavitation degradation of epoxy coatings. Therefore, this work used an ultrasonic cavitation tester to focus on the effect of solution temperature on the cavitation properties of 3 kinds of epoxy coatings in 3.5% NaCl. The cavitation properties were discussed basis on the material properties and environmental aspects. As the solution temperature increased, even though with large fluctuation, the cavitation degradation rates of A and B coatings were reduced rapidly, but the rate of C coating was decreased gradually. In addition to the cushioning effect, the reason that the cavitation degradation rate reduced with solution temperature was partly related to the brittle fracture and water absorptivity of the epoxy coatings, and the water density, but was little related to the shape and composition of the compound in the coatings or the phase transition of the epoxy coating.