• 제목/요약/키워드: Precursor

검색결과 3,462건 처리시간 0.032초

Neuroprotective Effects of Berberine in Neurodegeneration Model Rats Induced by Ibotenic Acid

  • Lim, Jung-Su;Kim, Hyo-Sup;Choi, Yoon-Seok;Kwon, Hyock-Man;Shin, Ki-Soon;Joung, In-Sil;Shin, Mi-Jung;Kim, Yun-Hee
    • Animal cells and systems
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    • 제12권4호
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    • pp.203-209
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    • 2008
  • Berberine, an isoquinoline alkaloid found in Coptidis Rhizoma(goldenthread) extract, has multiple pharmacological effects such as anti-inflammatory, antimicrobial and anti-ischemic effects. In the present study, we examined the effects of berberine on neuronal survival and differentiation in a hippocampal precursor cell line and in the memory deficient rat model. Berberine increased in a dose dependent manner the survival of hippocampal precursor cells as well as differentiated cells. In addition, berberine promoted neuronal differentiation of hippocampal precursor cells. In the memory deficient rat model induced by stereotaxic injection of ibotenic acid into entorhinal cortex(Ibo model), hippocampal cells were increased about 2.7 fold in the pyramidal layer of CA1 region and about 2 fold in the dentate gyrus by administration of berberine after 2 weeks of ibotenic acid injection. Furthermore, neuronal cells immunoreactive to calbindin were increased in the hippocampus and entorhinal cortex area by administration of berberine. Taken together, these results suggest that berberine has neuroprotective effect in the Ibo model rat brain by promoting the neuronal survival and differentiation.

조성이 다른 전구체 분말에 따른 Bi-2223/Ag 초전도 테이프의 특성 변화 (Properties of Bi-2223/Ag HTS tapes using different content of precursors)

  • 하동우;양주생;하홍수;오상수;황선역;이동훈;최정규;이언용;권영길
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2003년도 춘계학술대회 논문집 초전도 자성체 연구회
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    • pp.69-72
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    • 2003
  • Bi-2223 superconducting wires were fabricated by stacking, drawing process with different precursor powders and different heat-treatment histories. The precursor powders were 2 kinds of Pb content. And a part of the tapes were experienced pre-annealing process which caused tetragonal structure of Bi-2212 phase to orthorhombic structure of it was during drawing process. We confirmed the transformation of Bi-2212 phase from tetragonal structure to orthorhombic structure and reduction of second phases. XRD and DC magnetization analysis were performed in order to investigate the fraction of Bi-2223 phase in Bi-2223/Ag HTS tape. We could achieve best Ic of 70 A class at the Bi-2223/Ag tape using low Pb content of precursor powder and experienced pre-annealing process. DC magnetization analysis was useful to investigate the fraction of Bi-2223 phase in the Bi-2223/Ag tape.

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김수근에 대한 승효상 건축의 수정주의 행보 - 해럴드 블룸의 수정주의 변증법을 중심으로 - (The Revisionary Ratio and Architectural Identity of Seung, Hyo-Sang against the Precursor Kim, Swoo-Geun - Focusing on the Dialectic of Revisionism by Harold Bloom -)

  • 강윤식;강훈
    • 건축역사연구
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    • 제23권1호
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    • pp.51-62
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    • 2014
  • Architecture is a product of numerous influences, as shown in the apprenticeships of Kim, Jung-Up and Kim, Swoo-Geun with Le Corbusier's influences. Therefore, its identity is need to be re-defined based on such complex relationships. The rhetorical images of 'the Map of Misreading', as the core of the poetic identification proposed by Harold Bloom's 'the Theory of Influence', provide an efficient way of explaining the relations between architectural apprenticeships and identities. This research is to re-build a new methodology of architectural criticism based on it. The diachronic transformations of the architecture of Seung, Hyo-Sang also had very characteristic 'revisionary ratios' about his precursor Kim, Swoo-Geun. As an antithetic stance of his precursor's final phase, his early days works pursued continuously geometric abstraction and objective images of the architecture of Adolf Loos. However, his recent works are showing the obvious symptoms of regression to his origins. Finally, the architectural identity should be re-conceptualized as a complexity, based on inter-textuality from complex influences. This new architectural identity can be reflected into the modern obsessive identity.

Sonochemical Synthesis, Thermal Studies and X-ray Structure of Precursor [Zr(acac)3(H2O)2]Cl for Deposition of Thin Film of ZrO2 by Ultrasonic Aerosol Assisted Chemical Vapour Deposition

  • Hussain, Muzammil;Mazhar, Muhammad;Rauf, Muhammad Khawar;Ebihara, Masahiro;Hussain, Tajammal
    • Bulletin of the Korean Chemical Society
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    • 제30권1호
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    • pp.92-96
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    • 2009
  • A new precursor [$Zr(acac)_{3}(H_{2}O)_{2}$] was synthesized by Sonochemical technique and used to deposit thin $ZrO_{2}$ film on quartz and ceramic substrate via ultrasonic aerosol assisted chemical vapour deposition (UAACVD) at 300 ${^{\circ}C}$ in oxygen environment followed by annealing of the sample for 2-3 minutes at 500 ${^{\circ}C}$ in nitrogen ambient. The molecular structure of the precursor determined by single crystal X-ray analysis revealed that the molecules are linked through intermolecular hydrogen bonds forming pseudo six and eight membered rings. DSC and TGA/FTIR techniques were used to determine thermal behavior and decomposition temperature of the precursor and nature of evolved gas products. The optical measurement of annealed $ZrO_{2}$ film with tetragonal phase shows optical energy band gap of 5.01 eV. The particle size, morphology, surface structure and composition of deposited films were investigated by XRD, SEM and EDX.

암모니아 농도에 따른 Rich-Ni 양극 소재의 전구체 형태와 특성 변화 (Changes in the Shape and Properties of the Precursor of the Rich-Ni Cathode Materials by Ammonia Concentration)

  • 박선혜;홍순현;전형권;김천중
    • 한국재료학회지
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    • 제30권11호
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    • pp.636-640
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    • 2020
  • Due to the serious air pollution problem, interest in eco-friendly vehicles is increasing. Solving the problem of pollution will necessitate the securing of high energy storage technology for batteries, the driving force of eco-friendly vehicles. The reason for the continuing interest in the transition metal oxide LiMO2 as a cathode material with a layered structure is that lithium ions reveal high mobility in two-dimensional space. Therefore, it is important to investigate the effective intercalation and deintercalation pathways of Li+, which affect battery capacity, to understand the internal structure of the cathode particle and its effect on the electrochemical performance. In this study, for the cathode material, high nickel Ni0.8Co0.1Mn0.1(OH)2 precursor is synthesized by controlling the ammonia concentration. Thereafter, the shape of the primary particles of the precursor is investigated through SEM analysis; X-ray diffraction analysis is also performed. The electrochemical properties of LiNi0.8Co0.1Mn0.1O2 are evaluated after heat treatment.

Synthesis of Flake Type Micro Hollow Silica Using Mg(OH)2 Inorganic Template

  • Lee, Ji-Seon;Noh, Kyeong-Jae;Moon, Seong-Cheol;Lee, Young-Chul;Lee, Seong-Eui
    • 한국세라믹학회지
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    • 제54권3호
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    • pp.222-227
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    • 2017
  • Flake-type micro hollow silica was synthesized by precipitation method using an $Mg(OH)_2$ inorganic template and sodium silicate and ammonium sulfate as the silica precursors. We investigated the effects of the silica precursor concentration on the shape, shell thickness, and surface of the hollow silica. When the concentration of the silica precursor was 0.5 M, the hollow silica had a smooth and translucent thin shell, but the shell was broken. On the other hand, the shell thickness of the hollow silica changed in the range of 12 nm to 18 nm with the increase of the precursor concentration from 0.7 M to 1.1 M. Simultaneously, unintended spherical silica satellites were created on the shell surface. The number of satellites and the size rose according to the increased concentration of silica precursor. The reason for the formation of spherical silica satellites is that the $NH_4OH$ nucleus generated in the synthesis of hollow silica acted as another silica reaction site.

Si-N 전구체를 이용한 에폭시/실리카 나노복합재료의 제조 (Novel Preparation of Epoxy/Silica Nanocomposite Using Si-N Precursor)

  • 김이주;윤호규;이상수;김준경
    • 폴리머
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    • 제28권5호
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    • pp.391-396
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    • 2004
  • 기존의 에폭시/실리카 나노복합재료의 제조 방법에서 나타나는 문제점인 경화 반응 중의 휘발성 부산물 생성에 의한 미세기공 형성 및 치수 불안전성 등을 극복하고자 Si-N 전구체를 사용한 새로운 방법을 제안하고자 한다. 실리카 전구체로 부산물이 형성되지 않는 메틸트리페닐실란 (MTPS)을 합성하고 이를 이용하여 솔-젤 반응과 에폭시 경화 반응이 병행되는 동시 복합화 반응을 통하여 무기상의 고른 분산상태를 지닌 에폭시/실리카 나노복합재료를 제조하였으며, 이로부터 뛰어난 투명성뿐 아니라 기계적 물성과 열적특성에서 탁월한 물성의 증가를 얻을 수 있었다.

Study on the superhydrophilicity of $TiO_2$ films on glasses by thermal CVD

  • Choi, Jin-Woo;Cho, Sang-Jin;Nam, Sang-Hun;Kim, Young-Dok;Boo, Jin-Hyo
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2009년도 제38회 동계학술대회 초록집
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    • pp.100-100
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    • 2010
  • Hydrophilic $TiO_2$ films were deposited on slide glasses using titanium tetraisopropoxide (TTIP) as a precursor by metal-organic chemical vapor deposition (MOCVD). The temperature of substrate was $400^{\circ}C$ and the temperatures of precursor were kept at $75^{\circ}C$ (sample A) and $60^{\circ}C$ (sample B) during the $TiO_2$ film growth. The deposited $TiO_2$ films were characterized by contact angle measurement and uv/vis spectroscopy. The result show that sample B has very low contact angle of almost zero due to superhydrophilic $TiO_2$ surface and transmittance is $76.85%{\pm}1.47%$ at the range of 400 - 700 nm. So, this condition is very optimal for hydrophilic $TiO_2$ film deposition. However, when the temperature of precursor is lower is lower than $50^{\circ}C$ or higher than $75^{\circ}C$, $TiO_2$ could not be deposited on the substrate and cloudy $TiO_2$ film was formed due to low precursor temperature and the increase of surface roughness, respectively.

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PAN 전구체 섬유의 안정화시 전자선 전류의 영향 (Effect of Electron Beam Currents on Stabilization of Polyacrlonitrile Precursor Fiber)

  • 신혜경;전준표;김현빈;강필현
    • 방사선산업학회지
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    • 제5권1호
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    • pp.41-46
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    • 2011
  • Polyacrylonitrile (PAN) fibers are the most widely used precursor of the materials for carbon fibers. The conventional process of carbon fibers from PAN precursor fiber includes two step; stabilization at low temperature and carbonization at high temperature. Compared to thermal stabilization, the stabilization process by electron beam (E-beam) irradiation is a advanced and brief method. However, a stabilization by E-beam irradiation was required a high dose (over 5,000 kGy) and spend over 1.5 hr (1.14 MeV, 1 mA). In the present work the main goal is exploring a quick stabilization process by cotrolling E-beam currents. The effect of various E-beam currents on stabilization of PAN precursor fiber was studied by gel fraction test, thermo gravimertic analysis (TGA), differential scanning calorimetry (DSC), tensile strength, and scanning electron microscopy (SEM) images.

Harvesting of Oleaginous Microalgae Chlorella sp. by CaCO3 Mineralization

  • Kim, Dong Hyun;Oh, You-Kwan;Lee, Kyubock
    • 한국재료학회지
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    • 제31권7호
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    • pp.386-391
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    • 2021
  • The formation of CaCO3 in microalgal culture is investigated and applied for effective separation of microalgae. The presence of several cationic ions in the culture medium mediates the formation of 3 types of mineral precipitates depending on the concentration of mineral precursors, Ca2+ and CO32-, amorphous nano-flakes, rhombohedral calcites, and spherical vaterites. While amorphous phased precipitates are formed for all concentrations of mineral precursor, only calcites are formed for 30 mM solutions of mineral precursor, and mixtures of calcites and vaterites are formed for 50 and 100 mM solutions of mineral precursor. The harvesting efficiency is also dependent on the concentration of the mineral precursor: from 90 % for 10 mM to 99 % for 100 mM after 60 mins' of gravitational sedimentation. The formation of nano-flakes on the surface of microalgal cells induces the flocculation of microalgae by breaking the stable dispersion. The negatively charged surface of the microalgal cell is compatible not only with nano-flake attachment but also with the growth of calcitic crystals in which microalgal cells are embedded.