• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.38 no.4
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• pp.315-320
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• 2010

To improve not only the basic performance but also the fail-safe performance, power consumption of the main landing gear for helicopters, a semi-active control landing gear using hybrid MR damper, was introduced in this paper. This damper of the configuration to install a permanent magnet in a electromagnet MR damper, was designed by the trade-off study on permanent magnet location and a magnet field analysis. Force control algorithm which keep the sum of air spring force and damping force at a specified value during landing, was used for the controller. The drop simulations using ADAMS Model for this semi-active control landing gear, were done. The improvement of the preceding performances as the result to evaluate the landing performance by the simulations, has been confirmed.

• Applied Chemistry for Engineering
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• v.5 no.6
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• pp.1062-1067
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• 1994

The chemistry of 5-methyl-4-imidazolecarboxylic acid ester synthesis involves three distinct reaction steps. Of these the rate of formation of diketone was found to be a function of oxime and HCl concentration and temperature by the batch experiment. The decomposition of diketone was found to be a slow process whereas temperature was the only variable to affect it significantly. An empirical rate expression for the net formation of diketone fits the experminetal data satisfactorily. The principal objectives of this study are to study the kinetics of the diketone formation reaction and to develop the empirical rate expression.

• Molecules and Cells
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• v.37 no.12
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• pp.888-898
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• 2014

Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only effective drug and represents the preferred first-line treatment for chemotherapy. However, a high level of intrinsic or acquired resistance of pancreatic cancer to gemcitabine can contribute to the failure of gemcitabine treatment. To investigate the underlying molecular mechanisms for gemcitabine resistance in pancreatic cancer, we performed label-free quantification of protein expression in intrinsic gemcitabine-resistant and -sensitive human pancreatic adenocarcinoma cell lines using our improved proteomic strategy, combined with filter-aided sample preparation, single-shot liquid chromatography-mass spectrometry, enhanced spectral counting, and a statistical method based on a power law global error model. We identified 1931 proteins and quantified 787 differentially expressed proteins in the BxPC3, PANC-1, and HPDE cell lines. Bioinformatics analysis identified 15 epithelial to mesenchymal transition (EMT) markers and 13 EMT-related proteins that were closely associated with drug resistance were differentially expressed. Interestingly, 8 of these proteins were involved in glutathione and cysteine/methionine metabolism. These results suggest that proteins related to the EMT and glutathione metabolism play important roles in the development of intrinsic gemcitabine resistance by pancreatic cancer cell lines.

• Korean Journal of Food Science and Technology
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• v.24 no.6
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• pp.619-622
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• 1992

To increase utilization of Korean yam, the rheological properties of gelatinized yam (Dioscorea aimadoimo) starch solutions at various concentrations $(1{\sim}5%)$ and temperature $(30{\sim}60^{\circ}C)$ were investigated. The rheological behavior of gelatinized yam starch solutions was illustrated by power-law model and Casson equation and exhibited pseudoplastic behavior with yield stress. The pseudoplasticity of starch solutions increased largly concentration of starch increased. As the temperature increased from $30^{\circ}C$ to $60^{\circ}C$, the dependency of starch concentration decreased, B were decreased from 0.40449 to 0.39352. The activation energy of flow of gelatinized yam starch solutions were increased from 4.1415 to $5.45329{\times}10^6\;J/kg{\cdot}mol$ by increasing starch concentration from 1% to 5%.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.53 no.5
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• pp.681-687
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• 2020

Physicochemical properties of fucoidan and alginate extracted from Sargassium horneri were investigated. The alginates were extracted and purified via three different routes (CaCl₂, HCl and ethanol routes), and their rheological properties at various concentrations and temperatures were determined. The yield of fucoidan was 3.08%, and it was mainly composed of fucose and galactose. Fourier-transform infrared spectrum of fucoidan showed strong absorption band at 1,254 and 827 cm^-1 corresponding to the sulfate group. Flow behavior of the alginate solution was characterized using the power-law model. The consistency index increased with increasing concentrations. The sodium alginate solution (1.5%) exhibited Newtonian behavior when extracted via the CaCl₂ and HCl routes, while it exhibited pseudoplastic behavior when extracted via the ethanol route. The effect of temperature on the flow behavior was investigated in terms of the activation energy (E_a), which was obtained using the Arrhenius equation. The E_a value corresponding to the alginate solution decreased with increasing shear rates. The E_a values corresponding to the alginate solutions purified via the CaCl₂, HCl, and ethanol routes were 13.54-18.64 kJ/mol, 13.42-19.21 kJ/mol, and 9.51-10.67 kJ/mol, respectively. The low E_a values corresponding to the solutions extracted via the ethanol route suggest that the flow behavior does not depend significantly on temperature.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1325-1333
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• 2011

An analytical, numerical, and experimental comparison of the hydraulic and thermal performance of new vascular channels with semicircular cross sections was conducted. The following conditions were employed in the study: Reynolds number, 30-2000; cooling channels with a volume fraction of the cooling channels, 0.04; and pressure drop, $30-10^5$ Pa. Three flow configurations were considered: first, second, and third constructal structures with diameters optimized for hydraulic operations. To validate the proposed vascular designs by an analytical approach, 3-D numerical analysis was performed. The numerical model was also validated by the experimental data, and the comparison results were in excellent agreement in all cases. The validation study against the experimental data showed that compared to traditional channels, the optimized structure of the cooling plates could significantly enhance heat transfer and decrease pumping power.

• Steel and Composite Structures
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• v.34 no.4
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• pp.511-524
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• 2020

In this research, a simple four-variable trigonometric integral shear deformation model is proposed for the static behavior of advanced functionally graded (AFG) ceramic-metal plates supported by a two-parameter elastic foundation and subjected to a nonlinear hygro-thermo-mechanical load. The elastic properties, including both the thermal expansion and moisture coefficients of the plate, are also supposed to be varied within thickness direction by following a power law distribution in terms of volume fractions of the components of the material. The interest of the current theory is seen in its kinematics that use only four independent unknowns, while first-order plate theory and other higher-order plate theories require at least five unknowns. The "in-plane displacement field" of the proposed theory utilizes cosine functions in terms of thickness coordinates to calculate out-of-plane shear deformations. The vertical displacement includes flexural and shear components. The elastic foundation is introduced in mathematical modeling as a two-parameter Winkler-Pasternak foundation. The virtual displacement principle is applied to obtain the basic equations and a Navier solution technique is used to determine an analytical solution. The numerical results predicted by the proposed formulation are compared with results already published in the literature to demonstrate the accuracy and efficiency of the proposed theory. The influences of "moisture concentration", temperature, stiffness of foundation, shear deformation, geometric ratios and volume fraction variation on the mechanical behavior of AFG plates are examined and discussed in detail.

• Composites Research
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• v.12 no.2
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• pp.53-61
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• 1999

A failure criterion must be considered in each failure mode and loading condition to provide easy determining strength parameters, flexibility and rational simplicity. In this study, new failure criterion was developed by introducing equivalent strength under biaxial loading of tension and torsion. The experimental results showed that the equivalent biaxial strength has a power law relation with respect to a parameter, cos($tan^{-1}R_b$). Failure strength under biaxial loadings could be predicted as a function of tensile strength, torsional strength and biaxial ratio. The scattering of experimental data could be predicted using a Weibull distribution function and the concept of equivalent biaxial strength. Also, in this study, a fatigue theory was developed based on a plane stress model which enabled the S-N curve for combined stress states to be predicted from the S-N data for uniaxial loading. The prediction models can be predicted a biaxial strength and fatigue life of general laminated composite naterials under multi-axial loadings.

• Structural Engineering and Mechanics
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• v.66 no.3
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• pp.353-368
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• 2018

In this work, a high order hyperbolic shear deformation theory with four variables is presented to study the vibratory behavior of functionally graduated plates. The field of displacement of the theory used in this work is introduced indeterminate integral variables. In addition, the effect of porosity is studied. It is assumed that the material characteristics of the porous FGM plate, varies continuously in the direction of thickness as a function of the power law model in terms of volume fractions of constituents taken into account the homogeneous distribution of porosity. The equations of motion are obtained using the principle of virtual work. An analytical solution of the Navier type for free vibration analysis is obtained for a FGM plate for simply supported boundary conditions. A comparison of the results obtained with those of the literature is made to verify the accuracy and efficiency of the present theory. It can be concluded from his results that the current theory is not only accurate but also simple for the presentation of the response of free vibration and the effect of porosity on the latter.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.389-392
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• 2015

We identify a strong lensing galaxy in the cluster IRC 0218 that is spectroscopically confirmed to be at z = 1.62, making it the highest-redshift strong lens galaxy known. The lens is one of the two brightest cluster galaxies and lenses a background source galaxy into an arc and a counterimage. With Hubble Space Telescope (HST) grism and Keck/LRIS spectroscopy, we measure the source redshift to be $z_S=2.26$. Using HST imaging, we model the lens mass distribution with an elliptical power-law profile and account for the effects of the cluster halo and nearby galaxies. The Einstein radius is $^{\theta}E=0.38^{+0.02{\prime}{\prime}}_{-0.01}$ ($3.2^{+0.2}_{-0.1}kpc$) and the total enclosed mass is $M_{tot}(<^{\theta}_E)=1.8^{+0.2}_{-0.1}{\times}10^{11}M_{\odot}$. We estimate that the cluster environment contributes ~ 10% of this total mass. Assuming a Chabrier IMF, the dark matter fraction within $^{\theta}E$ is $f^{Chab}_{DM}=0.3^{+0.1}_{-0.3}$, while a Salpeter IMF is marginally inconsistent with the enclosed mass ($f^{Salp}_{DM}=-0.3^{+0.2}_{-0.5}$).