• Title/Summary/Keyword: Post injection

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Decreased post-operative pain using a sublingual injection of dexamethasone (8 mg) in lower third molar surgery

  • Gozali, Peiter;Boonsiriseth, Kiatanant;Kiattavornchareon, Sirichai;Khanijou, Manop;Wongsirichat, Natthamet
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.17 no.1
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    • pp.47-53
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    • 2017
  • Background: Every patient who undergoes mandibular third molar surgery is concerned about post-operative pain. Indeed, previous researchers have used various methods to treat such pain. This study aimed to assess the effectiveness of sublingual injection of dexamethasone (8 mg) to treat post-operative pain after mandibular third molar surgery. Method: This was a randomized, double-blind, split-mouth, clinical trial, involving 48 healthy patients who required surgical removal of two mandibular third molars with similar bilateral positions. All operations were performed by the same experienced surgeon. The patients were randomized into a study group (8 mg dexamethasone injection) and a placebo group (normal saline injection). Both interventions were injected into the sublingual space immediately after local anesthesia, 30 min before the first incision. The study group received an 8 mg dexamethasone injection, while the placebo group received a normal saline injection. The wash period between the patients' two operations was 3 to 4 weeks. Pain was assessed by recording the number of analgesic tablets (rescue drug) consumed, as well as by noting the patients' responses to the visual analog scale (VAS) on the first, second, and third days after surgery. Results: The study group differed significantly from the placebo group in terms of VAS score and analgesic consumption. Conclusion: Dexamethasone (8 mg), injected sublingually, significantly eased post-operative pain after surgical removal of the mandibular third molar.

Experimental Study on Reduction of Emissions for Marine Diesel Engines with a Double Post Injection (선박용 디젤엔진에서 이단지연분사에 따른 배기 배출물 저감에 관한 실험 연구)

  • Lee, Won-Ju;Choi, Jae-Hyuk;Cho, Kwon-Hae
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.4
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    • pp.418-424
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    • 2015
  • Marine Environment Protection Committee of the International Maritime Organization has decided to reinforce the NOx emission standards for ships passing an ECA(Emission Control Area) with Tier III standards from January 1, 2016. In this study, real-time measurements of the exhaust gas, cylinder pressure and fuel consumption were conducted at each load of a T/S Hanbada main engine of Korea Maritime and Ocean University, which is controlled by single injection and double post injection for reducing NOx emissions. The results showed that the quantity of CO2 and NOx increased in proportion to the engine load, whereas the CO concentration was inversely proportional to the engine load. In addition, double post injection decreased 10 % of P-max and reduced 25~30 % of the NOx emissions compared to single injection, whereas there was a trade-off relation, such as increase 3~5 % of SFOC (Specific Fuel Oil Consumption).

In vivo kinetics and biodistribution of a HIV-1 DNA vaccine after administration in mice

  • Kim, Byong-Moon;Lee, Dong-Sop;Kim, Chae-Young;Son, Mi-Won;Sung, Young-Chul;Kim, Won-Bae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.423.2-424
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    • 2002
  • The present study evaluates the pharmacokinetics and tissue distribution of GX-12, a multiple plasmid DNA vaccine for the treatment of HIV-1 infection. PCR analysis after i.v. injection in mice showed that plasmid DNA was rapidly degraded in blood with a half-life of 1.34 min and was no longer detectable at 90 min post-injection. Plasmid DNA concentration also rapidly declined at the injection site after i.m. injection. with less than 1 % of the initial concentration remaining at 90 min post-injection. (omitted)

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REACTION TIME, SEMEN OUTPUT AND SEMEN QUALITY OF BUFFALO BULLS AFTER PRE-COLLECTION INJECTION OF PROSTAGLANDIN F2 ALPHA (PGF2 ALPHA)

  • Capitan, S.S.;Antiporda, G.S.;Momongan, V.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.3 no.4
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    • pp.343-346
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    • 1990
  • A study was conducted to determine the effect of prostaglandin $F_2$ alpha ($PGF_2$ alpha) on the reaction time and seminal characteristics of buffalo bulls. Semen was collected from three Murrah bulls in three periods: pre-treatment, treatment and post-treatment. During the treatment period each bull was administered 2 ml $PGF_2$ alpha (Synchrocept, Fenprostalene) im, 1 hour prior to semen collection. In the post-treatment, semen was collected 7 days after the last injection of $PGF_2$. Semen samples were evaluated immediately after collection. Pre-collection injection of $PGF_2$ alpha has no significant effect on reaction time, semen volume, percentage motility, sperm concentration and total number of sperms per ejaculate. Fluctuations in semen color and consistency were observed. There is a significant (p<0.05) increase in the mean percentage of normal spermatozoa during the treatment and post treatment periods. Likewise, administration of PG results into a significant (p<0.05) rise on the average percentage of live sperms but this effect was not manifested in the post-treatment period. Improvement in mass activity was observed during the treatment and post-treatment periods.

Effects of Hydrogen Injection by In-Situ and Plasma Post-Treatment on Properties of a ZnO Channel Layer in Transparent Thin Film Transistors (증착시 및 플라즈마 후처리에 의한 수소 주입이 투명 박막 트랜지스터에서 산화아연 채널층의 물성에 미치는 영향)

  • Bang, Jung-Hwan;Kim, Won;Uhm, Hyun-Seok;Park, Jin-Seok
    • Journal of the Semiconductor & Display Technology
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    • v.9 no.1
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    • pp.35-40
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    • 2010
  • We have investigated the effects of hydrogen injection via in-situ gas addition ($O_2$, $H_2$, or $O_2$ + $H_2$ gas) and plasma post-treatment (Ar or Ar + H plasma) on material properties of ZnO that is considered to be as a channel layer in transparent thin film transistors. The variations in the electrical resistivity, optical transmittance and bandgap energy, and crystal quality of ZnO thin films were characterized in terms of the methods and conditions used in hydrogen injection. The resistivity was significantly decreased by injection of hydrogen; approximately $10^6\;{\Omega}cm$ for as-grown, $1.2\;{\times}\;10^2\;{\Omega}cm$ for in-situ with $O_2/H_2\;=\;2/3$ addition, and $0.1\;{\Omega}cm$ after Ar + H plasma treatment of 90 min. The average transmittance of ZnO films measured at a wavelength of 400-700 nm was gradually increased by increasing the post-treatment time in Ar + H plasma. The optical bandgap energy of ZnO films was almost monotonically increased by decreasing the $O_2/H_2$ ratio in in-situ gas addition or by increasing the post-treatment time in Ar + H plasma, while the post-treatment using Ar plasma hardly affected the bandgap energy. The role of hydrogen in ZnO was discussed by considering the creation and annihilation of oxygen vacancies as well as the formation of shallow donors by hydrogen.

Monitoring the Sonographic Ovarian Dynamics and Pregnancy Rate in Cyclic Murrah Buffalo Cows Synchronized with Prostaglandin F2α

  • Harun-or-Rashid, Mohammad;Phulia, SK;Hasan, Mir Md. Iqbal;Musharraf, Mohammad;Bhuiyan, Uddin;Juyena, Nasrin Sultana;Sharma, Rakesh Kumar
    • Journal of Animal Reproduction and Biotechnology
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    • v.35 no.1
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    • pp.50-57
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    • 2020
  • The objective of this research work was to know ovarian dynamics and pregnancy rate of cyclic Murrah buffalo cows with induced estrus by administration of prostaglandin F2α (PGF2α) and timed artificial insemination (TAI) with frozen thawed semen. A total of 31 female buffaloes were selected for the study. The buffalos having matured CL observed by ultrasonography were given one intra muscular injection of cloprostenol 500 ㎍ and TAI was performed using frozen thawed semen of Indian Murrah buffalo bull. Results showed that 90.32% (significantly, at p < 0.05) cows explore the sign of heat after injection of PG and 67.85% (significantly, at p < 0.05) cows were become pregnant out of 28 inseminated (TAI) cows. In the 28 inseminated (TAI) cows, average number of smaller and larger size of follicles were non-significantly (p > 0.05) higher at day 3 post PG injection, but the medium size of follicles was nonsignificantly (p > 0.05) higher at PG injection. At day 3 post PG injection the diameter of follicles was significantly (p < 0.05) higher, but the diameter of CL was significantly (p < 0.01) lower compared at PG injection. At PG injection the diameter of largest follicle was non-significantly differences (p > 0.05) in between pregnant and non-pregnant cows. But at day 3 post PG injection it was significantly (p < 0.01) higher in pregnant cows compared to non-pregnant cows. The number of small, medium, and large follicles at PG injection and at day 3 post PG injection were non-significantly (p > 0.05) difference in between pregnant and non-pregnant buffalo cows. Finally, it is concluded that the CL was effectively regresses and induced the sign of heat in buffalo cows and after AI the cows were become pregnant with significant rate. The study will help to the veterinarian and researcher to know the efficacy of PG injection and AI for reproductive efficiency in buffalo cows.

A study on the defects of molds for distribution polymer line post insulators and problem-solving measures (배전용 폴리머 라인 포스트 애자 금형의 불량과 대책에 관한 연구)

  • Kim, Sei-hwan;Choi, Kye-kwang
    • Design & Manufacturing
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    • v.6 no.2
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    • pp.12-16
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    • 2012
  • In this study, an injection mold is made to produce polymer line post insulators. FRP (fiber reinforced plastics) is covered by silicone housing. In injection molding process, chances for offcenter are 60 percent. Given the structure of the product, offcenter occurs owing to the imbalances in positions of gates and improper -designs of cores and jigs. This study focuses on mold modifications and improvements.

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Biological effect of recombinant IL-1$\beta$ on the expression of antiviral genes in the gill of rainbow trout, Oncorhynchus mykiss

  • Hyun, Do Jeong
    • Journal of fish pathology
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    • v.16 no.3
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    • pp.139-146
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    • 2003
  • We have investigated the biological effects of recombinant IL-1$\beta$ (rIL-1$\beta$) on the expression of antiviral genes such as Myxovirus-3 (MX-3) and Interferon regulating factor-1 (IRF-1), which are related to type I interferon. When ten micrograms of rIL-1$\beta$ were treated, we observed the stimulatory effect on the expression of these antiviral genes. Interestingly, at the early stage of stimulation, these genes were down-regulated and then up-regulated by the results obtained that the expressions of these genes were decreased at day 1 post-injection and gradually increased at day 3 post-injection. Thus, the stimulatory effect of rIL-1$\beta$ on the expression of MX-3 and IRF-3 gene might be an indirect stimulatory effect because significant up-regulation was delayed until day 3 post-injection.

A Study on Measurement of Shrinkage of Molded Plastics in a Microcellular Foaming Injection Molding Process (초미세 발포 사출 성형 공정에서 성형된 플라스틱의 수축률 측정에 관한 연구)

  • Hwang, Yun-Dong;Cha, Sung-Woon;Lee, Jung-Hyun
    • Proceedings of the KSME Conference
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    • 2001.06c
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    • pp.621-626
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    • 2001
  • Microcellular foaming process was developed at MIT in 1980's to save a quantity of raw materials and improve mechanical properties. There are many process variables in appling microcellular foaming process to the conventional injection molding process. Of all process variables, part dimension control and shrinkage are the most influential on the post molded dimension. The post molding dimensional change of thermoplastic resins is important to tool designers for predicting the specific difference of molded part vs. actual mold cavity. Generally, articles injection molded are smaller in size than the cavity; hence, the term shrinkage factor is used to define the allowance a designer specifies. It is important to consider the factors that influence molded part dimension. According to ASTM Designation: D 955, shrinkage from mold dimensions of molded plastics was measured. In injection molding, the difference between the dimensions of the mold and of the molded article produced therein from a given material may vary according to the design and operation of the mold. In this paper, shrinkage data of molded plastic parts was obtained. It can be an important information for designing optimum mold system in a microcellular foaming injection molding process.

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Alteration of Spindle Formation and Chromosome Alignment in Post-Ovulatory Aging of Mouse Oocytes

  • Kang, Hee-Gyoo;Cha, Byung-Hun;Jun, Jin-Hyun
    • Development and Reproduction
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    • v.15 no.3
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    • pp.231-237
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    • 2011
  • The objective of this study was to elucidate the dynamics of microtubules in post-ovulatory aging in vivo and in vitro of mouse oocytes. The fresh ovulated oocytes were obtained from oviducts of superovulated female ICR mice at 16 hours after hCG injection. The post-ovulatory aged oocytes were collected at 24 and 48 hours after hCG injection from in vivo and in vitro, respectively. Immunocytochemistry was performed on ${\beta}$-tubulin and acetylated ${\alpha}$-tubulin. The microtubules were localized in the spindle assembly, which was barrel-shaped or slightly pointed at its poles and located peripherally in the fresh ovulated oocytes. The frequency of misaligned metaphase chromosomes were significantly increased in post-ovulatory aged oocytes after 48 hours of hCG injection. The spindle length and width of post-ovulatory aged oocytes were significantly different from those of fresh ovulated oocytes, respectively. The staining intensity of acetylated ${\alpha}$-tubulin showed stronger in post-ovulatory aged oocytes than that in the fresh ovulated oocytes. In the aged oocytes, the spindles had moved towards the center of the oocytes from their original peripheral position and elongated, compared with the fresh ovulated oocytes. Microtubule organizing centers were formed and observed in the cytoplasm of the aged oocytes. On the contrary, it was not observed in the fresh ovulated oocytes. The alteration of spindle formation and chromosomes alignment substantiates the poor development and the increase of disorders from the post-ovulatory aged oocytes. It might be important to fertilize on time in ovulated oocytes for the developmental competence of embryos with normal karyotypes.