• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.2
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• pp.166-174
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• 2012

To determine the effects of Mahaengeuigam-tang(MHEGT) on obesity, the obesity-related factors (gastrin, CGRP, ghrelin, glucagon-like peptide-1, insulin, orexin, leptin, serotonin, NPY) were investigated in the stomach, pancreas, brain of mice by immunohistochemical methods for 4 weeks after Mahaengeuigam-tang(MHEGT) administration. The change of boy weight decreased in MHEGT administered group than that of control group. The immunohistochemical density of the gastrin and CGRP positive cells on pylorus of stomach increased in MHEGT administered group than that of control group. The number of ghrelin immunoreactive cells on stomach decreased in MHEGT administered groups than that of control group. The immunohistochemical density of GLP-1 in the pancreas decreased in MHEGT administered group than that of control group. The immunohistochemical density of insulin positive cells in the pancreas decreased in MHEGT administered group than that of control group. The immunohistochemical density of orexin and NPY positive neurons in the diencephalon was slightly stronger in MHEGT administered group than that of control group. The immunohistochemical density of serotonin and leptin positive neurons was stronger in MHEGT administered group than that of control group. These results demonstrate that Mahaengeuigam-tang(MHEGT) increased the immunohistochemical density of factors related to appetite inhibitors, and decreased the immunohistochemical density of factors related to stimulator of food intake in stomach, pancreas and brain.

• Journal of Korean Neurosurgical Society
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• v.56 no.2
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• pp.86-90
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• 2014

Objective : The spot sign is related with the risk of hematoma expansion in spontaneous intracerebral hemorrhage (ICH). However, not all spot sign positive patients undergo hematoma expansion. Thus, the present study investigates the specific factors enhancing the spot sign positivity in predicting hematoma expansion. Methods : We retrospectively studied 316 consecutive patients who presented between March 2009 to March 2011 with primary ICH and whose initial computed tomography brain angiography (CTA) was performed at our Emergency Department. Of these patients, 47 primary ICH patients presented spot signs in their CTA. We classified these 47 patients into two groups based on the presence of hematoma expansion then analyzed them with the following factors : gender, age, initial systolic blood pressure, history of anti-platelet therapy, volume and location of hematoma, time interval from symptom onset to initial CTA, spot sign number, axial dimension, and Hounsfield Unit (HU) of spot signs. Results : Of the 47 spot sign positive patients, hematoma expansion occurred in 26 patients (55.3%) while the remaining 21 (44.7%) showed no expansion. The time intervals from symptom onset to initial CTA were $2.42{\pm}1.24$ hours and $3.69{\pm}2.57$ hours for expansion and no expansion, respectively (p=0.031). The HU of spot signs were $192.12{\pm}45.97$ and $151.10{\pm}25.14$ for expansion and no expansion, respectively (p=0.001). Conclusions : The conditions of shorter time from symptom onset to initial CTA and higher HU of spot signs are the emphasizing factors for predicting hematoma expansion in spot sign positive patients.

• The Journal of Information Systems
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• v.26 no.4
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• pp.163-188
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• 2017

Purpose The purpose of this study is to empirically analyze the factors affecting the intention to use the IPA focusing on functional characteristics. Based on the research result, this research has significance in that it not only suggested strategic guidelines for the related business operators, it also helped identify the factors that will influence the intention to use an intelligent personal assistant centering on the functional characteristics of the IPA. Design/methodology/approach Accordingly, in an attempt to identify factors that will influence the intention to use the intelligent personal assistant, we proposed a research model, together with a corresponding hypothesis, which incorporates the functional characteristics (personalization, anthropomorphism, autonomy, communication ability, contextual offer) and perceived enjoyment of the intelligent personal assistant into a technology acceptance model. To verify the research hypothesis of this research, we have conducted a questionnaire survey with individuals who have used an intelligent personal assistant as target. And with the data collected from 215 copies of the questionnaire survey, we have carried out a path analysis using the PLS structural equation. Findings As a result, it turned out that, of the IPA functional characteristics, personalization had a positive effect on perceived usefulness, autonomy had a positive effect on perceived usefulness and perceived ease of use. Also, communication ability had a positive effect on perceived ease of use and perceived enjoyment, and anthropomorphism and contextual offer had a positive effect on perceived ease of use and perceived enjoyment and turned out to be major factors that increased the use intention of intelligent personal assistant.

• Journal of Korean Elementary Science Education
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• v.39 no.2
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• pp.183-203
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• 2020

The purpose of this study is to investigate the factor for improving elementary and secondary students' positive experiences about science (PES). In-depth interviews with 32 students and 8 teachers from 8 elementary and secondary Science Core schools were conducted to explore the factors for improving the student's PES. The analysis of the results reveal that the eight key factors which had a decisive impact on a student's PES were 'practice-centered exploratory activities', 'student-led class', 'positive and professional feedback', 'construction of knowledge through exploration', 'class considering student's interest and aptitude', 'use of materials related to real life', 'smooth communication and collaboration in group activities', and 'appropriate difficulty in learning content'. There were also five environmental factors that affected these key factors: 'teacher's professionalism for science classes', 'science class environment', 'teacher community in unit schools', 'change in curriculum', and 'scientific activities other than regular classes'. Based on these results, the practical implications for improving the student's PES are suggested.

• Child Health Nursing Research
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• v.21 no.2
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• pp.83-90
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• 2015

Purpose: The purpose of this study was to describe the subjective happiness and satisfaction with life of children with type 1 diabetes and explore related factors. Methods: A descriptive cross-sectional study design was used and the study was conducted with children at a diabetes camp. Data were collected using a self-report questionnaire to explore positive and negative psychological factors. The questionnaire included Subjective Happiness Scale, Satisfaction with Life Scale, Perceived Stress Scale and the Center for Epidemiological Studies Depression Scale for Children (CES-DC), Multidimensional Scale of Perceived Social Support, and General Self-Efficacy Scale. Results: Data from 15 children were used for data analysis. The correlational analysis results showed that subjective happiness was positively correlated satisfaction with life, social support, and self-efficacy, and was negatively correlated with perceived stress. Satisfaction with life was positively correlated social support, and was negatively correlated with perceived stress. Conclusion: Results indicate that the positive psychology factors were closely related with social support and self-efficacy and may alleviate perceived stress and depressive feelings. Therefore, researchers and clinicians should include positive psychological factors in their health management model for children with chronic illness.

• Communications of Mathematical Education
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• v.27 no.2
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• pp.135-163
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• 2013

This study dealt with the measurements of the positive psychological experience of high school students in relation to mathematics learning by using PPE-M. The purpose of this study is to compare the positive psychology of the high school students based on the grade and gender variables. Measured data for the purpose of this study examined the difference between the gifted students and the general students through a t-test. In addition, differences were analyzed by grade and gender variables. And One-way ANOVA was conducted to see the difference according to the course variables. The difference between the two groups was meaningful in PPE-M total score. There was meaningful difference in all of 5 areas and 19 factors except for 4 factors (Insight, Honesty, Full with pride, and Achievement). However, there was no difference according to grade levels. The comparison between the gender in the ordinary students shows meaningful difference in 11 factors, not in 12 (Judgment, Insight, Honesty, Prudence, Modesty & Kindness, Gratitude & Happiness, Flow, Superiority feeling, Achievement, High pleasure, Full with pride, and Self-efficacy). Affiliation makes meaningful difference in 22 factors except for Honesty.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3149-3152
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• 2012

Objective: The prognostic significance of perineural invasion (PNI) in gastric cancer has been previously investigated but not clearly clarified. The objective of our study was to investigate the role of PNI as prognostic factor in patients undergoing curative surgical resection and without distant metastasis in comparison with other clinicopathological factors. Methods: Between 2001 and 2010, 287 cases of gastric adenocarcinoma underwent radical gastrectomy recorded in hospital based registries. PNI was assessed as positive when cancer cells were seen in the perinerium or neural fascicles intramurally. Categorical and continuous variables were summarized using descriptive statistics and compared using chi-square and Mann-Whitney U tests, respectively. Cancer related survival rates were estimated by the Kaplan-Meier method. Results: PNI was positive in 211 of 287 cancers (73%), with a positive relation to lymph node metastases and advanced stage (p=0.0001, p=0.0001, respectively), mural invasion, and lymphatic and blood vessel invasion (p=0.0001, p=0.0001, respectively). The median survival of the PNI positive patients was significantly shorter than that of their PNI negative counterparts (24.1 versus 38.2 months, p=0.008). In the multivariate analysis, we detected PNI was an independent prognostic factor (p=0.025, HR=1.21, 95% CL 1.08-2.3) along with classical clinicopathological variables such as lymph node involvement (p=0.001), pT stage (p=0.03), and LVI (p=0.017), but not age, gender, tumour localization, stage, histologic type, and surgery procedure. Conclusions: PNI positivity in gastric cancers was related mural invasion, lymph node involvement, advanced stage and lymphatic and venous blood vessels. The presence of PNI appeared as an independent prognostic factor on survival on multivariate analysis, not influenced by tumor stage, lymph node metastases and other classical factors.

• The Journal of Information Systems
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• v.27 no.2
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• pp.29-52
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• 2018

Purpose As the number of SNS users increases, the importance of SNS advertisement is also increasing. Thus, the purpose of this study is to analyze the effect of factors on effectiveness of SNS advertising, and expand research on users' attitude and behavior intention toward SNS advertising. Design/methodology/approach This study was designed to examine the structural relationships among SNS service attribute, users' cognitive characters, psychological factors, users' attitude and behavior intention toward SNS advertising. Concretely, SNS service attribute was presented as online interactivity, and users' cognitive characters were presented as perceived relevance and perceived intrusiveness. In addition, psychological factors were presented as presence experience and message credibility, users' attitude toward SNS advertising was presented as advertisement attitude and users' behavior intention was presented as WOM. Findings The results showed that online interactivity has a positive effect on presence experience and message credibility, but perceived intrusiveness has a negative effect on presence experience and message credibility. Perceived relevance has a positive effect on presence experience, but does not have significant effect on message credibility. Presence experience and message credibility have positive effects on advertisement attitude and WOM, and advertisement attitude also has a positive effect on WOM. Based on the results from this study, academic and practical implications can be drawn. First, the study extended the scope of research about SNS advertising through focusing on SNS service attribute and SNS users' cognitive characters and identified the relationship between presence experience, message credibility, advertisement attitude and WOM. Second, the results of this research can provide practical guidelines to develop effective advertising strategies for companies which promoting SNS as a marketing tool.

• Journal of Preventive Medicine and Public Health
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• v.17 no.1
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• pp.223-229
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• 1984

An attempt to confirm the associations of some selected risk factors of HBV infection and measure their risks, a cross-sectional study with 1,209 urban office workers was carried out. For the study, a simple questionnaire which contained several questions on personal experience and behaviors on several known selected risk factors of HBV infection was applied to each subject, and the Hepatitis B virus surface antigen and its antibody were checked by RPHA and PHA method, respectively. Risk factors chosen for this study were experience of blood transfusion and personal contact variables, such as frequencies of eating-out, drinking after office hours, going to tea room, sharing cigarettes, etc. The results obtained were as follows: 1. The proportion of HBsAg positive was 10.6%, and total HVB infected including the Anti-HBs positive cases without vaccination was 44.2%. Both were higher in male than in female. 2. Frequent personal contact through glasses and dishes in eating-outs and drinkings turned out not to be a significant risk factor of Hepatitis B surface antigenecity. 3. Frequent visits to tea room was a significant risk factor of HBV infection which combined HBsAg positive cases and Anti-HBs cases who had not received HBV vaccination. The odds ratio was 1.56 4. Blood transfusion was not a significant risk factor of both HBsAg positive and total HBV infection. In summary, indirect oral contacts through eating-outs and drinkings was not significant risk factor in Korea at least between adults. Blood transfusion is no more major source of HBV infection in Korea probably because the adquate screening test of HBsAg for the blood donors is being made.

• Atmosphere
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• v.27 no.2
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• pp.163-175
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• 2017

The global terrestrial ecosystems have shown a large spatial variability in recent decades and represented a carbon sink pattern at mid-to-high latitude in Northern Hemisphere. However, there are many uncertainties in magnitude and spatial distribution of terrestrial carbon fluxes due to the effect of climate factors. So, it needs to accurately understand the spatio-temporal variations on carbon exchange flux with climate. This study focused on the effects of climate factors, .i.e. temperature, precipitation, and solar radiation, to terrestrial biosphere carbon flux. We used the terrestrial carbon flux that is simulated by a CarbonTracker, which performs data assimilation of global atmospheric $CO_2$ mole fraction measurements. We demonstrated significant interactions between Net Ecosystem Production (NEP) and climate factors by using the partial correlation analysis. NEP showed positive correlation with temperature at mid-to-high latitude in Northern Hemisphere but showed negative correlation pattern at $0-30^{\circ}N$. Also, NEP represented mostly negative correlation with precipitation at $60^{\circ}S-30^{\circ}N$. Solar radiation affected NEP positively at all latitudes and percentage of positive correlation at tropical regions was relatively lower than other latitudes. Spring and summer warming had potentially positive effect on NEP in Northern Hemisphere. On the other hand as increasing the temperature in autumn, NEP was largely reduced in most northern terrestrial ecosystems. The NEP variability that depends on climate factors also differently represented with the type of vegetation. Especially in crop regions, land carbon sinks had positive correlation with temperature but showed negative correlation with precipitation.