• Tuberculosis and Respiratory Diseases
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• 제44권4호
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• pp.922-929
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• 1997

저자들은 호흡곤란으로 내원한 환자에서, 외이, 코, 기관과 기관지를 침범한 재발성 다발성 연골염 1예를 경험하였기에 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제40권4호
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• pp.431-435
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• 1993

저자들은 호흡곤란으로 내원한 환자에서 외이, 눈, 코, 기관과 기관지를 침범한 재발성 다발성 연골염 1예를 경험하였기에 이를 보고한다.

• 대한후두음성언어의학회지
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• 제10권2호
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• pp.149-153
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• 1999

Relapsing polychondritis is an uncommon disorder of unknown etiology. That involves multisystem characterized by recurrent inflammation, degenerative change of multiple cartilaginous structures. The most common clinical manifestation is an auricular chondritis. Other involving systems are joint, nose, eye, larynx, trachea, aorta, heart and kidney. A 26-year-old man who complained of hoarseness and sore throat was referred to the ENT department from internal medicine department. On initial video-laryngoscopic and radiologic examination, there was no abnormal finding. Treatment with high doses of corticosteroid and methotrexate was not effective. Symptoms were aggrevated with dyspnea. Three months later, on video-laryngoscopic examination, bilateral cord fixation with swelling was noted. The radiologic finding showed subglottic stenosis due to collapse of anterior wall of cricoid cartilage. The condition was managed with tracheotomy. We report a case of relapsing polychondritis involving larynx and trachea with bilateral vocal cord palsy which was managed with tracheotomy.

• 대한기관식도과학회지
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• 제4권1호
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• pp.117-121
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• 1998

Relapsing polychondritis is a rare disesase involving any cartilaginous structure of entire body and is characterized by recurrent episode of inflammation and degeneration of cartilage and most commonly involve ear, nose, larynx, trachea, ribs, Eustachian tube, etc. Its signs and symptoms are recurrent swelling of auricle, saddle nose deformity, polyarthralgia, hoarseness and dyspnea, audiovestibular disturbance and cardiovascular abnormality, etc. Characteristic histologic findings are loss of normal basophilic staining of cartilage, perichondrial inflammatory infiltration with plamsa cells, lymphocytes and neutrophils, and finality, destruction of cartilage and replacement with scar tissue. Our case had saddle nose deformity, arthralgia, tracheal collapse, hearig loss and positive histologic finding but no auricular perichnodritis. Her major problem was airway. obstruction due to tracheal collapse. This case was diagnosed with relapsing polychondritis according to the Damiani's criteria. This case indicates that any patients complaining of airway obstruction have to be examined systemically.

• 대한두개안면성형외과학회지
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• 제20권5호
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• pp.341-344
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• 2019

Relapsing polychondritis (RP) is a rare autoimmune disorder of unknown etiology characterized by recurrent episodes of inflammation and the destruction of cartilaginous tissues, primarily involving the ear, nose, and the respiratory tract. Nasal chondritis is present in 24% of patients at the time of diagnosis and develops subsequently in 53% throughout the diseases progress. Progressive destruction of nasal cartilage leads to the characteristic flattening of the nasal bridge, resulting in the saddle nose deformity. In patients with RP, surgical management for saddle nose is carefully decided due to the disease relapsing characteristics. We present a RP patient with a saddle nose deformity who underwent reconstruction rhinoplasty with autologous costal cartilage grafting. At 6-month follow-up, the patient retained good esthetic results and showed neither complication nor relapse of RP.

• Journal of Yeungnam Medical Science
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• 제38권1호
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• pp.70-73
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• 2021

Relapsing polychondritis (RP) is a rare, progressive immune-mediated systemic inflammatory disease of unknown etiology, characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with other autoimmune diseases. However, the co-occurrence of RP and Crohn disease (CD) has rarely been reported. Herein, we present a 35-year-old woman diagnosed with RP and CD, who was refractory to initial conventional medications, including azathioprine and glucocorticoid, but who subsequently responded to infliximab (IFX). For both diseases, remission was sustained with IFX. There has been no previous report regarding the successful treatment of co-existing RP and CD with IFX.

• Tuberculosis and Respiratory Diseases
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• 제50권3호
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• pp.353-358
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• 2001

저자들은 이개염이 동반되지 않고 안장코와 다발성 관절염, 청력 감소, 기관지 침범 등이 동반된 재발성 다발성 연골염 환자에서 성문하 연부조직의 심한 부종으로 상기도 폐쇄가 동반되어 급성 호흡부전이 발생된 환자 1예를 경험하고 문헌고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제46권6호
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• pp.861-868
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• 1999

재발성 다발성 연골염은 전신 연골에 염증반응을 특징으로 하는 드문 전신 질환으로, 대개 외이나 비부의 연골 침범이 가장 흔한 증상이나, 이러한 특징적 증상 없이 기도에 연골염의 형태로 발현하는 경우도 드물게 보고되어 있다. 저자들은 최근 64세 남자에서 흔히 발생하는 연골의 침범에 의한 전형적인 증상없이 미만성 기도 연골 침범으로 발현한 재발성 다발성 연골염 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.