Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Relapsing Polychondritis Involved Tracheobronchial Tree

기관과 기관지를 침범한 재발성 다발성 연골염(Relapsing Polychondritis) 1예

  • Lee, Sang-Yeub (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Cho, Jae-Youn (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Lee, So-La (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Lee, Sang-Hwa (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Suh, Jung-Kyung (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Shim, Jae-Jeong (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Song, Gwan-Gyu (Department of Internal Medicine, College of Medicine, Korea University) ;
  • In, Kwang-Ho (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Kang, Kyung-Ho (Department of Internal Medicine, College of Medicine, Korea University) ;
  • Yoo, Se-Hwa (Department of Internal Medicine, College of Medicine, Korea University)
  • 이상엽 (고려대학교 의과대학 내과학교실) ;
  • 조재연 (고려대학교 의과대학 내과학교실) ;
  • 이소라 (고려대학교 의과대학 내과학교실) ;
  • 이상화 (고려대학교 의과대학 내과학교실) ;
  • 서정경 (고려대학교 의과대학 내과학교실) ;
  • 심재정 (고려대학교 의과대학 내과학교실) ;
  • 송관규 (고려대학교 의과대학 내과학교실) ;
  • 인광호 (고려대학교 의과대학 내과학교실) ;
  • 강경호 (고려대학교 의과대학 내과학교실) ;
  • 유세화 (고려대학교 의과대학 내과학교실)
  • Published : 1997.08.31
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Abstract

Relapsing polychondritis is a systemic disorder characterized by recurrent inflammation and degeneration of cartilaginous tissue throughout the body. The association with HLA-DR4 and the occurrence of antibodies to type II collagen and other autoantibodies suggest that an immunologic mechanism is involved in its pathogenesis. The eyes, ears, nose, larynx, trachea and articular areas are commonly involved. Airway narrowing or collapse from respiratory tract involvement occurs in up to 50% of patients with relapsing polychondritis. Treatment consists of administration of corticosteroids and other anti-inflammatory and immunosuppresive drugs. We experienced a case of relapsing polychondritis involving the tracheobronchial tree, nose and ears in a 49-year-old woman. The patient was clinically and histologically diagnosed as relapsing polychondritis according to McAdam's and Damiani's criteria. We report this case with a review of the literature.

저자들은 호흡곤란으로 내원한 환자에서, 외이, 코, 기관과 기관지를 침범한 재발성 다발성 연골염 1예를 경험하였기에 보고하는 바이다.

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