Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Co-existence of relapsing polychondritis and Crohn disease treated successfully with infliximab

  • Jung, Hye-In (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Kim, Hyun Jung (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Kim, Ji-Min (Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Lee, Ju Yup (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Park, Kyung Sik (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Cho, Kwang Bum (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Lee, Yoo Jin (Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine)
  • Received : 2020.04.28
  • Accepted : 2020.05.25
  • Published : 2021.01.31
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Abstract

Relapsing polychondritis (RP) is a rare, progressive immune-mediated systemic inflammatory disease of unknown etiology, characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with other autoimmune diseases. However, the co-occurrence of RP and Crohn disease (CD) has rarely been reported. Herein, we present a 35-year-old woman diagnosed with RP and CD, who was refractory to initial conventional medications, including azathioprine and glucocorticoid, but who subsequently responded to infliximab (IFX). For both diseases, remission was sustained with IFX. There has been no previous report regarding the successful treatment of co-existing RP and CD with IFX.

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References

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