• Journal of Korean Academy of Nursing
• /
• v.43 no.5
• /
• pp.579-586
• /
• 2013

Purpose: This article provides an update and overview of a nursing research program focused on understanding the pathophysiology and management of irritable bowel syndrome (IBS). Methods: This review includes English language papers from the United States, Europe, and Asia (e.g., South Korea) from 1999 to 2013. We addressed IBS as a health problem, emerging etiologies, diagnostic and treatment approaches and the importance of a biopsychosocial model. Results: IBS is a chronic, functional gastrointestinal disorder characterized by recurrent episodes of abdominal pain and alterations in bowel habit (diarrhea, constipation, mixed). It is a condition for which adults, particularly women ages 20-45, seek health care services in both the United States and South Korea. Clinically, nurses play key roles in symptom prevention and management including designing and implementing approaches to enhance the patients' self-management strategies. Multiple mechanisms are believed to participate in the development and maintenance of IBS symptoms including autonomic nervous system dysregulation, intestinal inflammation, intestinal dysbiosis, dietary intolerances, alterations in emotion regulation, heightened visceral pain sensitivity, hypothalamic-pituitary-adrenal dysregulation, and dysmotility. Because IBS tends to occur in families, genetic factors may also contribute to the pathophysiology. Patients with IBS often report a number of co-morbid disorders and/or symptoms including poor sleep. Conclusion: The key to planning effective management strategies is to understand the heterogeneity of this disorder. Interventions for IBS include non-pharmacological strategies such as cognitive behavior therapy, relaxation strategies, and exclusion diets.

• Journal of Nutrition and Health
• /
• v.20 no.4
• /
• pp.272-280
• /
• 1987

This research is intended to reveal the correlations between diabetes and dietary and other related factors. We were studied for 257 diabetics, in t도 9 general hospitals, located at Seoul, From August 109 to September 3, 1986. The result of this study can be follow ; 1) Distribution of the subjects according to their general characteristics ; The sex ration of the subjects is 1.06 ; 1.00 (male ; female), and the average age is 54.7 $\pm$10.9 years. Among the subjects 28.8% have a family history of diabetes ; the closer the genetic relationship, the more hereditory factors play a part. 2) Distribution of the scores according to their socioeconomic status ; As the socioeconomic status goes p, the intake of calories and fiber increases ; however, the frequency of eating out and the degree of physical activity decrease. 3) Relationship between obesity prevalence and each variable ; Among the subjects 27.2% are obese, and 60.3% have been obese in the past. Even though there is no significant relationship between the food habit and obesity, the number of people who are obese shows a significant increase as the socioeconomic status improves. 4) The effect of sex on each variable ; The intake of calories, sugar, alcohol and coffee is higher in male subjects, as is the frequency of eating out. In regular exercise and physical activity, there are significant differences between male and female subjects.

• Korean Medical Education Review
• /
• v.17 no.2
• /
• pp.57-59
• /
• 2015

Student research has been proposed as an educational strategy to fulfill the current requirements in basic medical education (BME) and to compatible with the self-directed development of professionalism. It is commonly accepted that the goals of student research are to develop the competencies of critical, reflective, and self-directed thinking; problem-solving; and creativity; as well as to acquire the skills necessary to search for information and analyze the literature; to cultivate the talent of mastering a specialized field through deeply intensified learning; and to establish close relationships between students and supervisors. To successfully implement student research, authorities on BME should to plan the procedure for the student research projects and allocate personal and material resources adequately in order to provide the opportunity for self-evaluation and reflection through the completion of daily records, to develop the habit of consistently evaluating one's own study, and to maintain a collegial relationship between students and supervisors by offering the proper feedbacks in a timely and consistent manner. In conclusion, despite several obstacles and difficulties in the establishment of successful student research projects, student research could provide students the motivation to develop themselves into expert academic researchers, and play a role in educating students to help solve patients' problems based on scientific evidence in the future.

• Journal of Microbiology and Biotechnology
• /
• v.14 no.4
• /
• pp.852-858
• /
• 2004

The morbidity and mortality of colon cancer are increasing, because of the westernization of food habit. Probiotics such as lactic acid bacteria (LAB) have been known to play an important role in retarding colon carcinogenesis by possibly influencing metabolic, immunologic, and protective functions in the colon. In this study, we evaluated the effect of B. polyfermenticus SCD on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) induced DNA damage in CHO-K, cells and human lymphocytes, and on proliferation of human colon cancer cell. Using the Comet assay to detect DNA damage, we found that B. polyfermenticus SCD protected cells from the DNA damage induced by MNNG in $CHO-K_1$ cells and in human lymphocytes. B. polyfermenticus SCD was also found to inhibit the growth of colon cancer cells in a dose-dependent manner, detected by the MTT assay. These results indicate that B. polyfermenticus SCD has the potential to inhibit not only DNA damage induced by a carcinogen, but also the proliferation of colon cancer cells.

• KDI Journal of Economic Policy
• /
• v.31 no.1
• /
• pp.1-25
• /
• 2009

This paper attempts to estimate the natural rates of output and interest of Korea in a simple DSGE set-up with a few stylized New Keynesian features using Bayesian methods. The major findings of this paper are as follows. First, the estimates of output gaps are less volatile than the measures from conventional approaches, although they exhibit non-negligible variations depending on the model specification. Another key finding is that the hybrid type Phillips curve with a backward-looking component and/or habit formation in consumption may play an important role in characterizing the macroeconomic dynamics of Korea.

• Tuberculosis and Respiratory Diseases
• /
• v.82 no.2
• /
• pp.94-101
• /
• 2019

Nontuberculous mycobacteria (NTM) are ubiquitous organisms that are generally found not only in the natural environment but also in the human engineered environment, including water, soil, and dust. These organisms can form biofilms and can be readily aerosolized because they are hydrophobic owing to the presence of the lipid-rich outer membrane. Aerosolization and subsequent inhalation were the major route of NTM lung disease. Water distribution systems and household plumbing are ideal habit for NTM and the main transmission route from natural water to household. NTM have been isolated from drinking water, faucets, pipelines, and water tanks. Studies that used genotyping have shown that NTM isolates from patients are identical to those in the environment, that is, from shower water, showerheads, tap water, and gardening soil. Humans are likely to be exposed to NTM in their homes through simple and daily activities, such as drinking, showering, or gardening. In addition to environmental factors, host factors play an important role in the development of NTM lung disease. The incidence and prevalence of NTM lung disease are increasing worldwide, and this disease is rapidly becoming a major public health problem. NTM lung disease is associated with substantially impaired quality of life, increased morbidity and mortality, and high medical costs. A more comprehensive understanding of the infection source and epidemiology of NTM is essential for the development of new strategies that can prevent and control NTM infection.

• Asia pacific journal of information systems
• /
• v.32 no.1
• /
• pp.92-124
• /
• 2022

Providing services using kiosks is actively carried out between suppliers and consumers. These service processes have recently begun to play a dominant role in transactions. However, previous self-service technology (SST) studies or kiosks have not fully reflected the changing environment surrounding these different technologies. To cover the updated business environments, we combined qualitative and quantitative research methods. Through qualitative research and a review of previous studies, the variables emphasized as motivations and constraints for kiosks use and those that can be newly illuminated were selected for this study. We then applied the variables to the research model to assess their influence. In terms of the motivations for using kiosks, the results suggest that perceived usefulness and compatibility as service quality, forced use, and perceived service providers' efficiency as provider polices, absorptive capacity, and habit as an individual characteristic and social influence as a subjective norm have a significant effect on the attitude toward kiosks. In terms of constraints, difficult to use and need for interaction predicts the attitude toward kiosks. Attitude toward kiosks, perceived behavioral control, and social influence are directly related to the intention to use kiosks. Lastly, intention to use kiosks plays a significant role as an antecedent of revisit intention. Using these empirical results, we propose both academic and practical implications for future kiosks use.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.16
• /
• pp.7077-7084
• /
• 2015

Background: Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy among males in India. While tobacco and alcohol are main aetiological factors, human papilloma virus (HPV) presence has surprisingly increased in head and neck Squamous Cell Carcinoma (HNSCC) in the past two decade but its frequency in OSCCS is still uncertain. We aim to explore the frequency of HPV and its major genotypes in North Indian patients and their association with clinicopathological and histopathological features and p16 expression pattern. Materials and Methods: The study group comprised 250 histologically proven cases of OSCC. HPV was detected by real time PCR in tumor biopsy specimens and confirmed by conventional PCR with PGMY09/PGMY11 primers. Genotyping for high-risk types 16/18 was conducted by type specific PCR. p16 expression was assessed by immunohistochemsitry. Results: HPV presence was confirmed in 23/250 (9.2%) OSCC cases, of which 30.4% had HPV 16 infection, 17.4%were positive for HPV 18 and 26.1% had co-infections. HPV presence was significantly associated with male gender (p=0.02) and habit of pan masala chewing (p=0.01). HPV positive cases also had a history of tobacco consumption in 91.3% cases. p16 over expression was observed in 39.1% of HPV positive cases but this was not significantly different from negative cases (p=0.54). Conclusions: The frequency of HPV in OSCC is low in North-India and majority of cases are associated with a tobacco habit. It appears that tobacco shows a confounding effect in HPV positive cases and use of p16 protein as a reliable marker to assess the potential etiological role of HPV in OSCC in our population is not suggested.

• Journal of the East Asian Society of Dietary Life
• /
• v.21 no.5
• /
• pp.756-770
• /
• 2011

This study was conducted on 419 middle school students (214 boys, 205 girls) in order to examine the general aspects, dietary habits, and performance of the school food services available to them in the Chungnam area. The mean age of the subjects was 15.1 years. The average heights and weights were 164.5 cm and 55.6 kg for boys and 158.9 cm and 49.4 kg for girls, respectively. The influence of parents was found to have a significant effect on the students' nutritional knowledge. Exactly 45.1% of subjects said that they needed time for nutritional education, and 54.2% of subjects answered that they have not received any nutritional education. The amount of spending money and expenditures for snacks per month were positively correlated with family income. Breakfast was skipped more than once per week in more than half of all students. Exactly 40.5% of subjects were satisfied with their schools' food services. As food services are more likely to correct unbalanced diets and provide an incentive for change towards better dietary habits, school food services can play a role in correcting unbalanced dietary behaviors.

• Journal of architectural history
• /
• v.7 no.3 s.16
• /
• pp.151-170
• /
• 1998

This study is about Le Corbusier's early years of loarning and training at La Chaux-de-Fonds. It is an attempt to show how Le Corbusier's groundwork was laid which characterize his work throughout the life. Charles Edouard Jeanneret was trained as a watch engraver and wished to be a painter. C. L'Eplattenier was to play a decisive role in shaping the young introspective boy's future. He encouraged Jeanneret's habit of the close study and observation of nature. Jeanneret was not the product of an established school, but instead made the unusual choice of educating himself. He found two indispensible sources of inspiration in study the past and in contemplating nature. His four years of self-education consisted of extensive reading, summer travels and winter layovers in larger cities-Vienna, Paris, Berlin-while sketching in museums or apprenticing local architects-Pellet, Behrens-. All these impressions then blended together to become part of a comprehensive source book of knowledge and imagination of the later Le Corbusier. A largely self-taught man, he never stopped making notes, drawing and writing, always aspiring to a clearer understanding of the meaning and underlying principles of objects and architecture. Jeanneret's five villas in La Chaux-de-Fonds are barometers which show the sequences of his development and change as an architect. In 1917, being thirty, he uprooted himself from his hometown to get a wider range of opportunities and moved to Paris. By that time Jeanneret was almost ready to blossom into Le Corbusier It was during this formative years of his life that Le Corbusier established the working method, mind-set and philosophical basis that determined the course of an architect in the making.