• Korean Journal of Computational Design and Engineering
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• v.21 no.2
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• pp.170-176
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• 2016

PLM system has been widely used in whole industry. Specially, in case of the company that constructs the engineering plant, PLM can be a key success tool for the innovation with ERP and Enterprise IT Systems. This paper describes the innovation strategy for engineering plant PLM including Master Data management, EPC project management, full 3D modeling and quality management.

• Journal of the Korean Society of Systems Engineering
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• v.11 no.1
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• pp.55-65
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• 2015

In steel making plant, sampling system for raw material such as iron ore, limestone is necessary for quality control purpose. For the sake of efficiency and productivity, automation of the sampling system is highly desirable. From technical standpoint, the development of the automated system requires multi-disciplinary domain knowledge such as mechanical engineering, industrial engineering, information technology and computer engineering. Up to present time, the development has been mainly carried out by a single domain expert with project manager. The automated system developed in this way caused problems in the final system. This paper suggests a systems engineering approach to the development of automation for raw material sampling plant via a tailored process called Plant Systems Engineering (PSE) Process based on ISO/IEC 15288. Through the PSE process, we could derive right requirements and architecture of the Systems Of Interest (SOI), and we were convinced that the PSE Process can be applied to many other Plant Systems.

• Journal of Korean Institute of Industrial Engineers
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• v.42 no.3
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• pp.241-248
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• 2016

Plant life cycle consists of design, construction, certification, operation, and maintenance phases, and various and enormous plant life cycle data is involved in each phase. Plant life cycle data should be linked with each other based on its proper relationships, so that plant operators can access necessary plant data during their regular operations and maintenance works. Currently, the relationships of plant life cycle data may not be defined explicitly, or they are scattered over several plant information systems. This paper proposes high level design of a plant life cycle data management system based on pre-defined plant life cycle database design. ISO-15926 standard is adapted for the database design. User-interface designs of the plant life cycle data management system are explained based on analysis of plant owners' requirements. A conceptual design of the database is also described with the entity-relationship diagram.

• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.3
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• pp.138-149
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• 2002

Plant cell culture provides a viable alternative over whole plant cultivation for the production of secondary metabolites. In order to successfully cultivate the plant cells at large scale, several engineering parameters such as, cell aggregation, mixing, aeration, and shear sensitivity are taken into account for selection of a suitable bioreactor. The media ingredients, their concentrations and the environmental factors are optimized for maximal synthesis of a desired metabolite. Increased productivity in a bioreactor can be achieved by selection of a proper cultivation strategy (batch, fed-batch, two-stage etc.), feeding of metabolic precursors and extraction of intracellular metabolites. Proper understanding and rigorous analysis of these parameters would pave the way towards the successful commercialization of plant cell bioprocesses.

• The Plant Pathology Journal
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• v.35 no.6
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• pp.692-697
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• 2019

Agrobacterium rhizogenes-mediated transformation of sugar beet hairy roots expressing single-chain variable fragment (scFv) was exploited to evaluate the efficacy of four antibody-based constructs for interfering with the Beet necrotic yellow vein virus infection. The scFv specific to a major coat protein of virus, p21, was targeted to various cellular compartments including the cytosol (pIC and pICC constructs), apoplast (pIA), and mitochondrion (pIM). After mechanical virus inoculation, most of the hairy root clones expressing scFv in the cytosol displayed low virus titers while the majority of transgenic hairy root clones accumulated antibody in outer membrane of mitochondria or apoplast were infected. This hairy root system provided an efficient and rapid approach to initially investigating root disease resistance like rhizomania prior to transform whole recalcitrant plants such as sugar beet.

• Journal of the Korean Society of Systems Engineering
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• v.11 no.2
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• pp.31-40
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• 2015

KEPCO International Nuclear Graduate School (KINGS) is dedicated to nurturing leadership-level professionals in nuclear power plant (NPP) engineering. KINGS have designed curriculum based on two philosophies. First, we balance aspects of discipline engineering, specialty engineering, and management engineering in the framework of systems engineering. Second, KINGS have designed the curriculum so that students can learn and experience the know-what, know-how and know-why level knowledge of NPP engineering and management. The specialization programs are opened during the 2nd year for 3 trimesters and those are a process of learning through practical project courses. The objectives of the specialization programs are to help students to learn the NPP life cycle technologies in highly structured and systematic ways. The systems engineer program (SEP) is one of the specialization programs. A practical case of the SEP which was applied to the project course for the NPP electric power system design education will be elaborated in this paper.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2018.11a
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• pp.456-457
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• 2018

• Journal of Plant Biotechnology
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• v.37 no.3
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• pp.250-261
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• 2010

The expression of vaccine antigens in transgenic plants has the potential to provide a convenient, stable, safe approach for oral vaccination alternative to traditional parenteral vaccines. Over the past two decades, many different vaccine antigens expressed via the plant nuclear genome have elicited appropriate immunoglobulin responses and have conferred protection upon oral delivery. Up to date, efforts to produce antigen proteins in plants have focused on potato, tobacco, tomato, banana, and seed (maize, rice, soybean, etc). The choice of promoters affects transgene transcription, resulting in changes not only in concentration, but also in the stage tissue and cell specificity of its expression. Inclusion of mucosal adjuvants during immunization with the vaccine antigen has been an important step towards the success of plant-derived vaccines. In animal and Phase I clinical trials several plant-derived vaccine antigens have been found to be safe and induce sufficiently high immune response. Future areas of research should further characterize the induction of the mucosal immune response and appropriate dosage for delivery system of animal and human vaccines. This article reviews the current status of development in the area of the use of plant for the development of oral vaccines.

• Nuclear Engineering and Technology
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• v.53 no.4
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• pp.1167-1175
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• 2021

The process of automation and monitoring in industrial control system involves the use of many types of sensors. A programmable logic controller plays an important role in the automation of the different processes in the power plant system. The major control units are boiler for temperature and pressure, turbine for speed of motor, generator for voltage, conveyer belt for fuel. The power plant units are controlled using microcontrollers and PLCs, but FPGA can be the feasible solution. The paper focused on the design and simulation of hardware chip to monitor boiler, turbine, generator and conveyer belt. The hardware chip of the plant is designed in Xilinx Vivado Simulator 17.4 software using VHDL programming. The methodology includes VHDL code design, simulation, verification and testing on Virtex-5 FPGA hardware. The system has four independent buzzers used to indicate the status of the boiler, generator, turbine motor and conveyer belt in on/off conditions respectively. The GSM is used to display corresponding message on the mobile to know the status of the device in on/off condition. The system is very much helpful for the industries working on plant automation with FPGA hardware integration.

• The KSFM Journal of Fluid Machinery
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• v.19 no.3
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• pp.33-36
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• 2016

The investigation on the verification of availability simulation for small-scale plant has been carried out. This study focuses on the availability variation induced by number of equipment and iteration with failure density function. The equipment classification of small-scale plant and failure type and the methodologies on Monte-Carlo simulation are established. The availability deviation with programs showed under Max. 1.7% for the case of normal function. This method could be used to availability evaluation of small-scale plant, but calibration of the failure density function is necessary for general application.