• The Journal of Advanced Prosthodontics
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• v.12 no.6
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• pp.329-337
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• 2020

PURPOSE. To verify the influence of computer-aided design/computer-aided manufacturing (CAD/CAM) implant-supported prostheses manufactured with cobalt-chromium (Co-Cr) and zirconia (Zr), and whether ceramic application, spark erosion, and simulation of masticatory cycles modify biomechanical parameters (marginal fit, screw-loosening torque, and strain) on the implant-supported system. MATERIALS AND METHODS. Ten full-arch fixed frameworks were manufactured by a CAD/CAM milling system with Co-Cr and Zr (n=5/group). The marginal fit between the abutment and frameworks was measured as stated by single-screw test. Screw-loosening torque evaluated screw stability, and strain analysis was explored on the implant-supported system. All analyses were performed at 3 distinct times: after framework manufacturing; after ceramic application in both materials' frameworks; and after the spark erosion in Co-Cr frameworks. Afterward, stability analysis was re-evaluated after 106 mechanical cycles (2 Hz/150-N) for both materials. Statistical analyses were performed by Kruskal-Wallis and Dunn tests (α=.05). RESULTS. No difference between the two materials was found for marginal fit, screwloosening torque, and strain after framework manufacturing (P>.05). Ceramic application did not affect the variables (P>.05). Spark erosion optimized marginal fit and strain medians for Co-Cr frameworks (P<.05). Screw-loosening torque was significantly reduced by masticatory simulation (P<.05) regardless of the framework materials. CONCLUSION. Co-Cr and Zr frameworks presented similar biomechanical behavior. Ceramic application had no effect on the biomechanical behavior of either material. Spark erosion was an effective technique to improve Co-Cr biomechanical behavior on the implant-supported system. Screw-loosening torque was reduced for both materials after masticatory simulation.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.11
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• pp.75-84
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• 2018

This study analyzed users' acceptance and intention to use in addition to needs and preferences of smart home technologies, and identified the differences in technology preference and acceptance by different factors. The subjects were residents in the 40s and 60s residing in the Seoul or suburbs of Seoul, and questionnaires were conducted in the 40s while interviews with questionnaires were conducted in the 60s. A total of 105 questionnaires were used as data, and frequency, mean, crossover, independent sample t test, one-way ANOVA and multiple regression analysis were performaed using SPSS23. The results of this study are as follows. First, hypertension, hyperlipidemia and hypercholesterolemia were the most common diseases among respondents and if there was no discomfort, they would like to continue living in the homes of the current residence. Therefore, the direction of smart home development should support the daily living and health care so that residents can live a healthy life for a long time in their living space. Second, the technologies that residents most need were a control technology of residential environments and a monitoring technology of residents' health and physiological changes. The most preferred sensor types are motion sensors and speech recognition while video cameras have a very low preference. Third, technology anxiety was the most significant factor influencing intention to accept smart home technology. The greater the technology anxiety is, the weaker the acceptance of technology. Fourth, when applying smart residential technology in homes, various resident characteristics should be considered. Age and technology intimacy were the most influential variables, and accordingly there were differences in technology preference and acceptance. Therefore, a user-friendly smart home plan should be done in the consideration of the results.

• Journal of Biomedical Engineering Research
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• v.43 no.3
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• pp.161-169
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• 2022

Engagement is an important factor in the field of rehabilitation as it is a known factor that have a positive influence on functional gaining in people who receive rehabilitation therapy. Although a number of measurements for engagement have been recently developed, investigation of possible factors that may have influence on engagement is not well established. Currently available evidence suggests that engagement is affected by mood and it is hypothesized that a personal factor may contribute to engagement. Therefore, this study aims to test the hypothetical relationship between mood and engagement while performing a manual dexterity task through an experiment in healthy participants prior to investigation on people with medical condition who requires rehabilitation therapy. After inducing target mood (positive or negative mood) for study participants by asking them to recall autobiographical memories, change in muscle activity, which was operationalized as an indicator of engagement, was investigated. Electromyogram (EMG) was recorded from four muscle areas in non-dominant hand side to quantify muscle activity. The results show that the target moods were appropriately induced with the method. Although there were subtle differences in the level of engagement between different moods, certain variables derived from muscle activity were significantly different; mean amplitude for wrist extensor EMG showed significant difference between different moods (Z = -2.023, p < .05) indicating that muscle activities in the wrist extensor are greater for positive mood than negative mood region during manual dexterity task. Meanwhile, performance outcomes of Minnesota Manual Dexterity Test (MMDT), such as mean completion time and number of errors, between moods showed no significant difference in two different moods, resulting in MMDT administration may not be useful task in distinguishing the level of rehabilitation engagement.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.47-58
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• 2021

Purpose : This study aimed to investigate the association between asthma and oral health and factors influencing asthma in adults. We also investigated whether asthma is related to mental health and physiological factors of blood. Methods : Data from 12,639 adults was taken from the 7th period (2016~2018) Korea National Health and Nutrition Examination Survey and analyzed using with SPSS 22.0 statistical program. Statistical analysis of data included frequency analysis, cross-analysis, and logistic regression analysis. For continuous data, an independent sample t-test was performed. The statistical significance level was defined as 0.05. Results : The probability of asthma occurrence was statistically different within general characteristics (gender, age, school grade, income, and drinking). By independent variables in a logistic regression analysis, the asthma diagnosis group had more people with speech discomfort (OR=1.37), chewing discomfort (OR=1.29), and oral pain (OR=.73). We found that people with asthma had a more unfavorable perception of their health (OR=1.73), suffered more depression (OR=.45), stress (OR=.66), and limited activity (OR=2.38). Moreover, the white blood cell count (OR=1.10) and high sensitivity C-reactive protein test (OR=1.06) also showed higher values than the control group. Conclusion : Our study showed that oral health and mental health were associated with the asthma, and influencing factors were oral health and behavior and mental health-related characteristics. Therefore, it is necessary to understand asthma-related risk factors for oral health and recognize the importance of systematic oral care education and regular dental visits for patients receiving asthma treatment. Thus, this study provides valuable insights on appropriate oral health management and prevention of asthma in patients.

• Proceedings of the ESK Conference
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• 1996.10a
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• pp.47-55
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• 1996

This study developed a comprehensive and easily applicable nuclear reactor control system evaluation method using reactor operators behavioral and mental workload database. A proposed control panel design cycle consists of the 5 steps: (1) finding out inconvenient, erroneous, and mentally stressful factors for the proposed design through evaluative experiments, (2) drafting improved design alternatives considering detective factors found out in the step (1), (3) comparative experiements for the design alternatives, (4) selecting a best design alternative, (5) returning to the step (1) and repeating the design cycle. Reactor operators behavioral and mental workload database collected from evaluative experiments in the step (1) and comparative experiments in the step (3) of the design cycle have a key roll in finding out defective factors and yielding the criteria for selection of the proposed reactor control systems. The behavioral database was designed to include the major informations about reactor operators' control behaviors: beginning time of operations, involved displays, classification of observational behaviors, dehaviors, decisions, involved control devices, classification of control behaviors, communications, emotional status, opinions for man-machine interface, and system event log. The database for mental workload scored from various physiological variables-EEG, EOG, ECG, and respir- ation pattern-was developed to indicate the most stressful situation during reactor control operations and to give hints for defective design factors. An experimental test for the evaluation method applied to the Compact Nuclear Simulator (CNS) installed in Korea Atomic Energy Research Institute (KAERI) suggested that some defective design factors of analog indicators should be improved and that automatization of power control to a target level would give relaxation to the subject operators in stressful situation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.5
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• pp.193-208
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• 2022

In this study, we proposed a mathematical model that can explain the source of the observed variability of repeated measurement data collected in Korean medicine clinical practice, and conducted a pilot analysis to infer the source of these variability based on our model. Mathematical model was constructed by dividing the observed variations into three components: common time-dependent variations, signal shift, and measurement error. To show the applicability of our model in real data, we analyzed 20 repeated measurement data of Korean clinical indicators in graduate students of Pusan National University Graduate School of Korean Medicine. We showed how to infer each source of variations based on our model and also showed the limitation of inference given the acquired the dataset. On the basis of objective recognition of these source of the variability, we hope that quantitative investigations on these sources for each Korean medicine clinical indicator are made in the future, so that they can be used in the clinical and educational areas of Korean medicine.

• Genomics & Informatics
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• v.21 no.3
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• pp.30.1-30.13
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• 2023

Ephs belong to the largest family of receptor tyrosine kinase and are highly conserved both sequentially and structurally. The structural organization of Eph is similar to other receptor tyrosine kinases; constituting the extracellular ligand binding domain, a fibronectin domain followed by intracellular juxtamembrane kinase, and SAM domain. Eph binds to respective ephrin ligand, through the ligand binding domain and forms a tetrameric complex to activate the kinase domain. Eph-ephrin regulates many downstream pathways that lead to physiological events such as cell migration, proliferation, and growth. Therefore, considering the importance of Eph-ephrin class of protein in tumorigenesis, 7,620 clinically reported missense mutations belonging to the class of variables of unknown significance were retrieved from cBioPortal and evaluated for pathogenicity. Thirty-two mutations predicted to be pathogenic using SIFT, Polyphen-2, PROVEAN, SNPs&GO, PMut, iSTABLE, and PremPS in-silico tools were found located either in critical functional regions or encompassing interactions at the binding interface of Eph-ephrin. However, seven were reported in nonsmall cell lung cancer (NSCLC). Considering the relevance of receptor tyrosine kinases and Eph in NSCLC, these seven mutations were assessed for change in the folding pattern using molecular dynamic simulation. Structural alterations, stability, flexibility, compactness, and solvent-exposed area was observed in EphA3 Trp790Cys, EphA7 Leu749Phe, EphB1 Gly685Cys, EphB4 Val748Ala, and Ephrin A2 Trp112Cys. Hence, it can be concluded that the evaluated mutations have potential to alter the folding pattern and thus can be further validated by in-vitro, structural and in-vivo studies for clinical management.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1340-1349
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• 2023

Despite its profound impact on athletic performance, the significance of heart rate recovery (HRR) has been insufficiently addressed in the filed of sports science, particularly in the context of weightlifting characterized by brief and intense exertions involving heavy weights. Serving as a valuable indicator of autonomic nervous system and cardiovascular function, HRR assumes a pivotal role in weightlifting. This comprehensive review aims to delineate the specific demands for HRR in weightlifting, shedding light on the often overlooked cardiovascular considerations within training regimes focused on strength and power. The investigation scrutinizes the repercussions of HRR on weightlifting performance, seeking to elucidate how inadequate recovery intervals may result in physiological and psychological consequences. These consequences encompass a distorted perception of effort, disruption of coordination, compromised posture due to irregular breathing, and an overall decline in lifting capacity. The review systematically presents compelling evidence pertaining to heart rate response and recovery patterns during weightlifting, underscoring the critical importance of well-structured rest periods. Furthermore, the review delves into a comprehensive discussion of factors influencing HRR in weightlifting, encompassing variables such as sex, age, cardiovascular function, hydration, nutrition, and psychological aspects. Finally, a key emphasis is placed on the integration of effective HRR techniques into the training regimens of weightlifters, thereby ensuring sustained and optimized performance outcomes.

• Journal of Korean Society of Forest Science
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• v.101 no.4
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• pp.626-634
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• 2012

The purpose of this study was to investigate the potential of persimmon vinegar as a functional beverage by analyzing the effects of persimmon vinegar ingestion on the energy substrate during endurance exercise. The healthy male adolescents (n=8) drunk persimmon vinegar ingested trial (PSV) or purified water ingested trial as the control trial (CON) 1 h prior to the exercise with the 60% of maximal oxygen uptake ($\dot{V}O_{2max}$) for 1 h. The exercise intensity was increased to the 80% of $\dot{V}O_{2max}$ and remained until exhaustion. And, the physiological variables, blood components, and amounts of energy oxidation were analyzed. There was no significant difference between trials in physiological variables, and the heart rates after exhaustion were higher in PSV compared to CON. There was no significant difference between trials in blood glucose level, while the blood lactic acids decreased significantly in PSV 30 and 60 minutes after onset of exercise. The free fatty acids concentration increased significantly in PSV from 15 minutes to 60 minutes after onset of exercise. The carbohydrate oxidation decreased significantly in PSV from 45 minutes after exercise and, on the contrary, the fatty acids oxidation increased significantly for the same period. And, fatty acids oxidation was higher in PSV compared to CON even after exhaustion. The respiratory exchange ratio was lower significantly in PSV compared to CON from 30 minutes to 60 minutes after exercise, whereas lower in CON after total exhaustion. The exercise time to exhaustion was 41% longer in PSV compared to CON. These results showed that the persimmon vinegar increase the level of lipids metabolism and decrease sense of fatigue by inhibiting carbohydrate oxidation during moderate intensity exercise, suggesting the possibility of using of persimmon vinegar as exercise functional beverage when ingested 1 h prior to the endurance exercise performance.

• Journal of Korean Public Health Nursing
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• v.8 no.2
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• pp.101-113
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• 1994

Maternity means all the women who are capable to conceive. In the aspect of health and medical care. however. it means the women who are now in pregnancy or have already given birth to a baby or are in a period of being recoverd from physiological changes occurred by pregnancy. According to the rapidly changing social structure. both the Quality and Quantity of the capacity of childbirth experienced by women are changing. Our society. having established a great economical growth by virtue of the highly developing and growing industrialization and urbanization. stimulates the women's advance into society and thereby increasing the number of employed women. When the women's participation in society is increased. their age of marriage is also affected. Which means there are a decrease of the capacity of childbirth in terms of quantity and a trend for women to have less children and to deliver a baby in their old age in terms of quality. On the contrary. since the number of multipara who want to have a baby in their old age is increasing. as a counter functional effect to the political project of decrease of a birth rate. concern has been focussed on childbirth in old age in the present study. And also such kind of the childbirth may be danger to the health of both mother and baby. Therefore the present study intended to provide some basic data of health education in the part of the health management of both mother and baby in the general hospital. based on understanding the realities of childbirth in. old age and things related to them. To achieve such a purpose of the present study. an analytical study by means of SPSS. was done using the data of 269 clinical records on both the newborn .babies and their mothers who had been supported by public general hospitals located in Seoul for 3 years from Jan. 1. 1991 to Dec. 31. 1993. Some significant results from the analytic study are as follows: 1. It appeared that the average age of normal. natural delivery was 33.8 years old and the average age of delivery through the cesarean operation was 35.4 years old. 2. It appeared that danger factors to childbirth women were types of the delivery and placental extrusion and danger factors to newborn babies are not so outstanding. 3. It appeared that the variables of the childbirth capacity which showed a significant difference according to each age group of women were the number of pregnancy. number of still birth, and number of existing children. That is. the age group of 'more than 35 years' had more frequency of experience In all 3 variables than the age group of 'less than 35 years'. 4. It appeared that the variables of the childbrith capacity which showed a significant difference a according to the sex of a newborn baby were number of pregnancy, number of still birth, and number of existing children. That is, the age group of 'more than 35 years' had more frequency of experience in all 3 variables than the age group of 'less than 35 years'. 5. It appeared that the health index of newborn babies which showed a significant difference was only 5 minute APGAR. That is, the health index 9.46 in the age group of 'more than 35 years' was less than an index of 9.72 in the age group of 'less than 35 years'. 6. Since a counter correlation of -0.10, as Pearson Correlation Coefficient, was showed between the age of childbirth mothers and the weight of newborn babies, it indicated that the higher age of childbirth woman, the lesser the weight of newborn baby. 7. It appeared that the number of women who had confirmed the sex of their baby before their delivery were 45 women, $67.2\%$ of total 67 women who had delivered a baby. and the expected sex by women in childbed was male with $73.1\%$ of total childbirth women expecting male birth and with their expression of feeling of female delivery. very regretful' by $39.3\%$ of total childbirth women. The results as shown above may indicate that instead of the possibility of danger to both the mother delivering a baby in old age and the baby delivered, the expectation of getting a son motivates childbirth in old age. As a conclusion, in a dimension of general hospital as well as national reform. it is required that a program of health education for childbirth in late maternal age have to be developed in the part of the health management of both mother and baby in the near future.