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http://dx.doi.org/10.15188/kjopp.2022.10.36.5.193

Proposal of a Mathematical Model for Variations in Repeated Measurement of Korean Medicine Clinical Variables and its Applicability to Education  

Hayeong, Jeong (Department of Physiology, College of Oriental Medicine, Gachon University)
Young-Kyu, Kwon (Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University)
Chang-Eop, Kim (Department of Physiology, College of Oriental Medicine, Gachon University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.36, no.5, 2022 , pp. 193-208 More about this Journal
Abstract
In this study, we proposed a mathematical model that can explain the source of the observed variability of repeated measurement data collected in Korean medicine clinical practice, and conducted a pilot analysis to infer the source of these variability based on our model. Mathematical model was constructed by dividing the observed variations into three components: common time-dependent variations, signal shift, and measurement error. To show the applicability of our model in real data, we analyzed 20 repeated measurement data of Korean clinical indicators in graduate students of Pusan National University Graduate School of Korean Medicine. We showed how to infer each source of variations based on our model and also showed the limitation of inference given the acquired the dataset. On the basis of objective recognition of these source of the variability, we hope that quantitative investigations on these sources for each Korean medicine clinical indicator are made in the future, so that they can be used in the clinical and educational areas of Korean medicine.
Keywords
Korean medicine clinical indicators; Repeated measurements; Normal variability; Korean medicine education;
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