• Bulletin of the Korean Chemical Society
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• v.28 no.11
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• pp.1910-1916
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• 2007

Analyzed are recent advances in design of novel boronared conjugates of synthetic and natural porphyrins and chlorins. These compounds showed high efficacy as cytotoxic agents for tumor cells in culture and as phototoxins in photodynamic therapy of tumor xenografts. Thus, boronated porphyrins and chlorins emerge as promising class of anticancer agents with potentially multiple advantages: the chemotherapeutic drugs alone and photo- and radiosensitizers in binary treatments.

• Rapid Communication in Photoscience
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• v.4 no.2
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• pp.41-44
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• 2015

Biomolecular photo-damaging activity of a water-soluble cationic porphyrin was examined using human serum albumin (HSA), a water-soluble protein as a target biomolecule model by a fluorometry. Dichlorophosphorus(V) tetraphenylporphyrin ($Cl_2P(V)TPP$), was synthesized and used as a photosensitizer. This porphyrin could bind to HSA and cause the photosensitized oxidation of HSA through the singlet oxygen generation and the oxidative photo-induced electron transfer (ET). Near infrared emission spectroscopy demonstrated the photosensitized singlet oxygen generation by this porphyrin. Decrement of the fluorescence lifetime of $Cl_2P(V)TPP$ by HSA supported the ET mechanism. Furthermore, the estimated Gibb's energy indicated that the ET mechanism is possible in the terms of energy. Because oxygen concentration in cancer cell is relatively low, ET mechanism is considered to be advantageous for photosensitizer of photodynamic therapy.

• Journal of the Korean Society of Radiology
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• v.6 no.3
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• pp.207-215
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• 2012

As one of photo dynamic therapies, the existing LED photo irradiation method with 635 nm continuous wave has most frequently been used for acne treatment, it suffered from a low energy efficiency and generation of a large amount of heat in tissues requiring improvement measures. In this thesis, a LED photo irradiation system for acne treatment has been designed using PWM(Pulse Width Modulation) mode to enhance the energy efficiency and prevent thermal destruction in tissues. System configuration consisting largely of timer module, PWM module, and photo transfer device has been designed with the use of 1 W LED at a wavelength of 660 nm for the photo transfer device to increase skin penetration depth for treatment of acne. Frequency and wave form generated by using PWM control was verified along with confirmation of output energy of 660 nm LED and surface temperatures of tissues, followed by evaluation of stable energy outputs and stability of tissues. The results indicated that whereas power loss was high and thermal destruction in tissues was exhibited when C.W mode was used to obtain the optical energy of 1 W LED at a wavelength of 660 nm for acne treatment, realization of PWM mode allowed lowering of power consumption for LED through pulse width modulation, and no occurrence of thermal destruction in tissues, suggesting that PWM mode is safer and more effective for treatment of acne than C.W mode.

• The Journal of the Korea Contents Association
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• v.15 no.6
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• pp.283-289
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• 2015

Recently, high energy photon radiotherapy is a growing trend for increasing therapy results. Commonly, if you use high energy photons above 6~8 MeV nominal accelerator voltage, It lead the photo-nuclear reaction and the generation of photo-neutron are accompanied and these problematic factors are issued in the view of radiation protection. Therefore, in this study analyzed for dose distribution of photo-neutron in radiotherapy room based on MCNPX. As a result, absorbed dose is increased sharply from 10 MV to 12 MV. It was founded that the rapid increasement of photoneutron fluence was related to the absorbed dose at above 10 MV. Also, in case of the recommendation of ICRP 103, the outcome of an exchanged equivalent dose which based on calculated an absorbed dose, showed lower equivalent dose than ICRP 60 by reflecting the contribution of secondary photon for absorbed dose of human body in the low energy band.

• Physical Therapy Korea
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• v.23 no.3
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• pp.29-39
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• 2016

Background: In the treatment of temporomandibular joint (TMJ) disorder, the goals of traditional physical therapy are not only to reduce the inflammatory process leading to pain, but also to decrease joint overload and muscle hyperactivity. To achieve those goals, physical therapists generally use a photo-therapy, joint mobilization, and massage. Objects: To examine the impact of an unloading technique using non-elastic taping on the pain, opening mouth, functional level, and quality of life in patients with TMJ disorder. Method: Twenty patients with TMJ disorder were included in this study and randomly divided into the experimental ($n_1$=10), and control ($n_2$=10) groups. Traditional physical therapy including massage and stretching for 30 min was performed in both groups. Non-elastic taping was performed in the experimental group after traditional physical therapy, and they were recommended to keep the tape attached for 12 hours. Outcomes for pain, functional level, and quality of life were measured using a survey. The opening mouth was measured using a general ruler. Result: Significant differences were observed in the pain level, opening mouth, functional level, and quality of life after the intervention and on follow-up in both groups. However, we found that while the levels of all parameters were maintained throughout the follow-up period in the experimental group, the functional status level was not maintained throughout the follow-up period in the control group. Conclusion: Our unloading technique using non-elastic tape results comparable to those achieved by traditional physical therapy in the treatment of TMJ. However, the unloading taping method using non-elastic tape is more effective than traditional physical therapy in maintaining the impact of intervention.

• Fashion & Textile Research Journal
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• v.10 no.6
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• pp.1014-1022
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• 2008

This study focuses on practical appliance of color therapy to skin care. After visiting the notion of color therapy and skin care, this study considers the ideas and background theories for diagnosis of constitution and skin. Cosmic duals force five element theory developed in China was the first introduction; Ayurvedic medicine and seven chakra notion are examined. Cosmic duals force five element theory, an idea describing the composition and movement rule of the cosmic components, adopted five colors(white, yellow, red, blue, and black) for cure purposes. In future, mental effect of the color is examined in the latter part of this study. The practice of the color therapy assigns solarized cream treatment and photo therapy, simultaneously proposes the use of color therapy to the skin care. For the diagnosis of the constitution, cosmic duals force five element theory and ayurvedic medicine are followed in a sequence. Cosmic duals force five element theory introduces five colors. Constitution medicine considers four types, ayurvedic medicine adopts three types, and seven colors are mentioned as chakra colors. Such a variations lead to possible disagreement on constitution analysis and driven colors. This study adopts the above methodologies for selecting potential color therapy for skin care. Adopt of selected cases are purely a part of the proposal. Initially, examined theories serve as a pilot for selecting a representative hypothesis. Followed selection of constitution and matched color for the use of the skin care are the scope of this study. In summary, background methodologies are implemented for the calculation of color therapy.

• Korean Institute of Interior Design Journal
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• v.20 no.4
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• pp.29-36
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• 2011

This study aims to be the useful resources for selecting play therapy facility in the future by analysis of used colors in the play therapy facility as the subsequent studies of the thesis of KIID in 2010, titled 'Study on the planning factors of case study for children's play therapy center'. As research method of this study, the overall understanding about play therapy facility was improved through theoretical considerations, and it was about the Moon-Spencer's theory of color harmony which will be used for the framework of case study. In Section 3, the field trips at 6 facilities were conducted as the case research and the data research through website was conducted for case study. Moon-Spencer's theory of color harmony used the Munsell's color Order System, so after measuring CMYK value of the picture for the case research through photo shop, the color, brightness and saturation were measured through Munsell Conversion program. The following three kinds of features were drawn by research of the harmony and disharmony of used colors for the cases after substituting the theory of color harmony through the measured color. brightness, and saturation. First. series Y and YR were used mainly for warm image as the concept of play therapy room. Second, the various colors were used for comfortable image like home. But the various patterns were used by mixing for the therapy room F, so it gives confusing impression. Third, series YR and achromatic color as the color of wood were used unavoidably for using materials of manufactured goods.

• Journal of Photoscience
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• v.8 no.2
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• pp.70-73
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• 2001

The chlorin-bromine building block was constructed and applied to synthesize $\delta$-bromo compounds of methyl pyropheophorbide-a. The visible spectra of the title compounds were discussed.

• Journal of Biomedical Engineering Research
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• v.37 no.4
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• pp.134-139
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• 2016

US Food and Drug Administration (FDA) approved as a innovative cure for cancer, 1996. The effect is death of cancer cells through necrosis, apoptosis. Mainly the Continuous Wave mode (CW) use for PDT Laser. It sting, the question including itch, and etc. Reportedly, the increase of temperature with the perforated edema, ulcer, necrosis. The Thermal relaxation time and Oxygen recovery time is necessary. To give a normal oxygen recovery time of the cell, used Pulse mode. Progress, it was Burst Pulse mode when easing the thermal wake, the simplicity was secured, the PDT effect is good. Excepted in control group CW, Pulse, Burst pulse mode were incubated with various concentrations of 5-aminolevulinic acid hydrochloride (ALA-5). The tumor size reduction CW mode (44%), Pulse mode (48%), Burst pulse mode (53%) at 4 week after PDT with 0.3, 0.3, 0.3 mg/ml of ALA-5. After 4 hours, investigation of 100, 100, $100J/cm^2$ laser irradiation. The pulse mode was superior in expirimental data analysis. And it was the Burst pulse mode edge head of a family effect.

• The Journal of Korean Physical Therapy
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• v.29 no.3
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• pp.145-151
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• 2017

Purpose: The purpose of this study was to investigate the validity and reliability of the measurement of shoulder joint motions using an inertial measurement unit (IMU). Methods: For this study, 33 participants (32 females and 1 male) were recruited. The subjects were passively positioned with the shoulder placed at specific angles using a goniometer (shoulder flexion $0^{\circ}-170^{\circ}$, abduction $0^{\circ}-170^{\circ}$, external rotation $0^{\circ}-90^{\circ}$, and internal rotation $0^{\circ}-60^{\circ}$ angles). Kinematic data on the shoulder joints were simultaneously obtained using IMU three-dimensional (3D) angular measurement (MyoMotion) and photographic measurement. Test-retest reliability and concurrent validity were examined. Results: The MyoMotion system provided good to very good relative reliability with small standard error of measurement (SEM) and minimal detectable change (MDC) values from all three planes. It also presented acceptable validity, except for some of shoulder flexion, shoulder external rotation, and shoulder abduction. There was a trend for the shoulder joint measurements to be underestimated using the IMU 3D angular measurement system compared to the goniometer and photo methods in all planes. Conclusion: The IMU 3D angular measurement provided a reliable measurement and presented acceptable validity. However, it showed relatively low accuracy in some shoulder positions. Therefore, using the MyoMotion measurement system to assess shoulder joint angles would be recommended only with careful consideration and supervision in all situations.