• 한국약용작물학회지
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• 제14권6호
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• pp.347-353
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• 2006

This study was conducted to evaluate the vegetation structure and ordination of the Peucedanum japonicum Thunb. community by the Phytosociological method, floristic composition table on east coast of South Korea. The vegetation of Peucedanum japonicum Thunb. community was classified into 2 communities such as the Aster Spathulifolius community and the calystegia soldanella-Artemisia princeps community. Vegetation of the Peucedanum japonicum Thunb. community with the Aster spathulifolius community was shown southward, whereas vegetation of Peucedanum japonicum Thunb. community with the calystegia soldanella-Artemisia princeps community was shown northward from the base line of Pohang at North latitude of 36" 05'. Accordingly, the Peucedanum japonicum Thunb. community was grown commonly with the Aster spathulifolius community southward of the base line of Pohang, whereas it was grown commonly with the calystegia soldanella-Artemisia princeps community northward on the east coast. All environmental conditions of habitat taken together, the optimum habitat of Peucedanum japonicum Thunb. was at Ulsan geographically and the middle region of sea cliff topography, and was suitable for alkali. sandyloam.

• 한국약용작물학회지
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• 제15권5호
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• pp.357-361
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• 2007

This study was conducted to evaluate the vegetation structure of the Peucedanum japonicum community by the phytosociological method of floristic composition table and cluster analysis on the southern coast of Korea. The vegetation of the Peucedanum japonicum community was classified mainly into 2 communities such as the Miscanthus sinensis community and the Lysimachia mauritiana-Rosa wichuraiana community. The Carex boottiana and Sedum oryzifolium community were classified as the lower rank of Miscanthus sinensis community. On level 1 of the cluster analysis of plant species, they were classified into Lysimachia mauritiana and Rosa wichuraiana group, also Miscanthus sinensis, Carex boottiana and Sedum oryzifolium in Peucedanum japonicum community, which is similar to the community classification shown in the synoptic table. On level 1 of the cluster analysis of relev, inland coast with Jejudo was Lysimachia mauritiana and Rosa wichuraiana of group such as level 1 of the cluster analysis of plant species, and island coast with Geomundo was Miscanthus sinensis Carex boottiana and Sedum oryzifolium of group such as cluster analysis of plant species.

• 식물병연구
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• 제27권3호
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• pp.115-119
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• 2021

2020년 경상북도 포항군 연일읍의 갯기름나물 재배 농가포장에서 잎에 작은 갈색 반점이 형성되고 잎끝부터 갈변되며 고사하는 증상이 발생하였다. 균총은 흰색에서 연한 회색을 띠었다. 균핵은 검은색의 구형 또는 타원형이었다. 자낭반은 컵모양이며, 크기는 0.5-0.9 cm이었다. 자낭은 원통형이고 크기는 75-240×5.9-17.3 ㎛이었다. 자낭포자는 무색의 타원형이었으며 크기는 8.4-10.7×4.8-5.8 ㎛이었다. Internal transcribed spacer (ITS) 1과 ITS4 영역의 염기서열 분석결과 Sclerotinia sclerotiorum과 100% 일치하였으며, 이와 같은 병원균의 균학적 특징, 병원성 검정 결과 그리고 염기서열 분석결과를 바탕으로 갯기름나물 잎반점과 마름 증상의 원인균은 S. sclerotiorum으로 동정하였으며, 이 병을 갯기름나물 균핵병으로 명명할 것을 제안한다.

• 한국환경생태학회지
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• 제21권1호
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• pp.74-81
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• 2007

본 연구는 한국 갯기름나물의 지형적 분포와 해식애 군집구조의 기초자료로 제공하기 위하여 해안과 지형별 종조성 및 생육양상을 조사한 바 이의 결과를 요약하면 다음과 같다. 갯기름나물과 동반 출현하는 식물은 57과 130속에 속한 170 분류군이었으며, 과별로는 국화과가 30 분류군으로 가장 많았다. 출현빈도가 가장 높은 식물은 해국(54.1%)이었고, 해안별로는 동해안과 서해안에서 해국, 남해안에서 억새의 출현빈도가 가장 높았다. 해안별 공통종은 서해안과 남해안간이 35.6%(47 분류군)로서 가장 높았고 다음으로 동해안과 서해안(30.4%), 동해안과 남해안(26.4%)순이었다. 갯기름나물이 출현하는 해안지형은 경사도 $17.4^{\circ}$의 해식애 암석해안, 평탄면, 암괴원, 수평절리, 수직절리, 요철지형이었고 지형 별 분포지역은 암석해안이 61 지역으로 가장 많았다. 군도에 따른 갯기름나물의 생육양상은 군도계급 3이 83지역(54.6%)으로서 가장 많았다.

• 생약학회지
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• 제49권3호
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• pp.225-230
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• 2018

3',4'-Disenecioylkhellactone is one of khellactone-type coumarins isolated from the roots of Peucedanum japonicum Thunb. However, its pharmacological effects are still little understood. In the present study, we investigated the inhibitory effect of 3',4'-disenecioylkhellactone on growth of gastric cancer cells. 3',4'-Disenecioylkhellactone strongly suppressed cell proliferation and induced caspase-mediated apoptosis in AGS human gastric cancer cells. Analysis of phospho-antibody arrays revealed 3',4'-disenecioylkhellactone effectively suppressed signal transducer and activator of transcription 3 (STAT3) tyrosine phosphorylation. 3',4'-Disenecioylkhellactone decreased STAT3 translocation to the nucleus and expression of STAT3 target genes. In addition, we examined the level of STAT3 activation in several gastric cancer cells and found that the inhibition of STAT3 phosphorylation by 3',4'-disenecioylkhellactone was associated with gastric cancer cell proliferation. Taken together, this study provides evidence for the first time that 3',4'-disenecioylkhellactone may be a potential therapeutic agent for the prevention or treatment of gastric cancer.

• 한국식품저장유통학회지
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• 제20권5호
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• pp.628-635
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• 2013

본 연구는 주로 blanching하여 나물로 섭취되고 있는 갯기름나물을 데침 과정에 의한 일반성분 및 영양성분 함량변화를 측정하였다. Blanching에 의해 조지방, 조회분 및 탄수화물의 함량은 유의적인 차이는 없었으나, 조단백질의 함량은 유의적으로 감소하였다. 갯기름나물의 검출된 모든 유리당의 함량 모두 blanching에 의해 감소되어, 총 유리당 함량은 14.8% 감소되었다. 생 갯기름나물에 비하여 데친 갯기름나물의 총 구성 아미노산 및 필수 아미노산의 함량의 함량은 각각 10.75%와 15.22% 감소되었고, 검출된 모든 구성 아미노산의 함량 모두 blanching에 의해 감소되었다. 총 지방산 함량은 blanching 전후 유의차가 없었다. 총 유기산 함량은 blanching에 의해 37.03% 감소되었고, 유기산 중 acetic acid의 감소가 가장 크게 나타났다. Blanching에 의해 비타민 A, E 및 C의 함량은 각각 20.20%, 8.23% 및 35.59% 감소되었다. 총 무기질 함량은 21.84% 감소되었고, 무기질 중 K 함량의 손실이 가장 컸다. 본 연구 결과 갯기름 나물은 필수 아미노산, 비타민 C, 무기질 등 유용한 영양성분들을 함유하고 있어 갯기름나물을 이용한 기능성 소재로의 활용 가치가 높을 것으로 생각되므로, blanching에 의해 대부분의 영양성분들이 감소되어 향후 이러한 성분들을 유지할 수 있는 blanching 조건 설정이 필요하다.

• 한국자원식물학회지
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• 제27권3호
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• pp.215-222
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• 2014

This study was conducted to isolate a compound with anticancer properties from the roots of Peucedanum japonicum Thunb. (Umbelliferae), and to evaluate the efficacy of that compound's anticancer activity. The $CHCl_3$ layer was purified via repeated column chromatography and recrystallization. The two compounds isolated from $CHCl_3$ layer were identified via NMR spectroscopic analysis as (10E) 1,10-heptadecadiene-4,6-diyne-3,8,9-triol (Comp. I) and anomalin (Comp. II). (10E) 1,10-heptadecadiene-4,6-diyne-3,8,9-triol was the first report from the roots of P. japonicum. MTT assays were conducted to evaluate the in vitro cytotoxic activities of Compounds I and II against the following human cancer cell lines: HeLa, HepG2, SNU-16, and AGS. Comp. I evidenced the most profound cytotoxic activity against HepG2 cells ($IC_{50}=6.04{\mu}g/mL$), and Comp. II exhibited the most profound cytotoxic activity against SNU-16 cells ($IC_{50}=18.24{\mu}g/mL$) among the human cancer cell lines tested in this study. However, no significant cell death was observed in the CCD-25Lu human normal lung fibroblast cells. Quantitative analysis using UPLC (Ultra Performance Liquid Chromatography) showed that the roots of P. japonicum contained 0.015 (Comp. I) and 1.69 mg/g (Comp. II) of these compounds.

• 한국약용작물학회지
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• 제13권2호
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• pp.75-79
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• 2005

Five coumarins, psoralen (1), scopoletin (2), isoimperatorin (4), (+)-marmesin (5) and xanthotoxin (6), three chromones, cimifugin (3), hamaudol (7) and sec-O-glucosylhamaudol (10), one sterol, daucosterol (8) and one aliphatic alcohol, galactitol (9) were isolated from the root of Peucedanum japonicum. Their chemical structures were identified by the physicochemical and spectroscopic data by comparing literature values. Among them, compounds 9 and 10 were isolated for the first time from this plant. The anti-inflammatory effects of isolated compounds were examined on cyclooxygenase (COX), compounds 1, 2 and 7 showed inhibitory activity on COX-1 with $IC_{50}$ values of 0.88, 0.27 and 0.30 mM, respectively. In the test for COX-2 activity, only compound 7 showed significant inhibitory activity with the $IC_{50}$ value of 0.57 mM. The other compounds exhibited weak inhibitory or no inhibitory activity.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2008년도 추계학술발표회
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• pp.167-168
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• 2008

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2007년도 추계학술발표회
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• pp.315.1-315.1
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• 2007