• FOCUS: LIFE SCIENCE
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• no.1
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• pp.7.1-7.4
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• 2024

The document "Understanding the Relationship Between Particle Size, Performance, and Pressure" explores the impact of particle size on chromatographic performance and system pressure. The study highlights how smaller particles can improve separation efficiency by providing higher resolution and faster analysis times. However, this comes at the cost of increased backpressure, which can challenge the system's hardware and require higher operating pressures. The document discusses the balance needed between particle size, column dimensions, and system pressure to optimize performance without exceeding the pressure limits of chromatographic systems. It outlines the advantages of using superficially porous particles (SPPs) over fully porous particles (FPPs) in achieving high efficiency with lower backpressure. The study also emphasizes the importance of selecting appropriate column dimensions and flow rates to manage system pressure while maintaining optimal performance. In conclusion, understanding the interplay between particle size, performance, and pressure is crucial for optimizing chromatographic separations, ensuring system longevity, and achieving high-quality analytical results.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.61-62
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• 2006

In this paper, using Bianchi's model with channel idle probability we analyze performance of power management scheme of IEEE 802.11 DCF according to ATIM window size and number of nodes for wireless ad hoc networks. The analytical results show that, when the number of nodes is given, the selected ATIM window size limits the performance.

• Structural Engineering and Mechanics
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• v.67 no.6
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• pp.587-601
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• 2018

Elevated water tanks are inverted pendulum type structures where drift limit is an important criterion for seismic design and performance evaluation. Explicit drift criteria for elevated water tanks are not available in the literature. In this study, probabilistic approach is used to determine maximum drift limit for damage state of yielding and damage state of collapse for the elevated water tanks supported on RC frame staging. The two damage states are defined using results of incremental dynamic analysis wherein a total of 2160 nonlinear time history analyses are performed using twelve artificial spectrum compatible ground motions. Analytical fragility curves are developed using two-parameter lognormal distribution. The maximum allowable drifts corresponding to yield and collapse level requirements are estimated for different tank capacities. Finally, a single fragility curve is developed which provides maximum drift values for the different probability of damage. Further, for rational consideration of the uncertainties in design, three confidence levels are selected and corresponding drift limits for damage states of yielding and collapse are proposed. These values of maximum drift can be used in performance-based seismic design for a particular damage state depending on the level of confidence.

• Korean Journal of Pharmacognosy
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• v.40 no.3
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• pp.224-228
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• 2009

For the quality control of traditional herbal medicine, Galgeun tang, simultaneous determination of glycyrrhizin, paeoniflorin, puerarin, 6-gingerol was established by using a high performance liquid chromatographic (HPLC) method with diode array detector. To separate five four constituents, DIONEX $C_{18}$ column ($5{\mu}m$, $120{\AA}$, $4.6\;mm{\times}150\;mm$) was used with gradient elution system of water and methanol. Validation of the chromatography method was evaluated by linearity, recovery, and precision test. Calibration curve of standard components showed excellent linearity ($R^2$>0.9906). Limits of detection (LOD) and limits of quantification (LOQ) varied from 0.15 to $0.52{\mu}g$/ml and 0.27 to $0.80{\mu}mg$/ml, respectively. The relative standard deviations (RSDs) of data of the intra-day and inter-day experiments were less than 2.88% and 1.21%, respectively. The results of recovery test were ranged from 96.71 to 106.29% with RSD values 0.01-0.80%.

• Journal of the Korean Society of Propulsion Engineers
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• v.15 no.1
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• pp.11-18
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• 2011

The geometrically similar swiss roll reactors of different physical sizes were tested with the aim of independently determining the effects of Re and Da. It is found that the difference between catalytic and non-catalytic combustions extinction limits are narrowed as scale decreases. In addition to assess the importance of fuel chemistry, different families of fuels including alkanes and ethers were tested. From these results the effect of scale and fuel type on microscale reactor performance and implications for practical micro combustion devices are discussed.

• Journal of the Korean Society of Food Culture
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• v.35 no.3
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• pp.278-284
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• 2020

In this study, biotin (vitamin B7) contents of frequently consumed foods in Korea were determined by using immunoaffinity column in conjunction with high-performance liquid chromatography (HPLC). The biotin contents of 24 foods of plant origin and 27 foods of animal origin were selected. The highest biotin contents in frequently consumed foods of plant origin were found in red beans (Huinguseul; 11.475 ㎍/100 g). On the other hand, biotin was not detected in any varieties of sorghum. For frequently consumed foods of animal origin, salted pollack roe (7.486 ㎍/100 g) showed the highest biotin content. However, beef and fish contained less biotin. All biotin analyses were conducted under analytical quality control. The limits of detection and limits of quantification of biotin were 0.007 and 0.023 ㎍/100 g, respectively, and the accuracy/recovery percentage was 95.35-105.02%. The precision values were 4.041% (repeatability) and 3.835% (reproducibility). Taken together, our data provide reliable data on the biotin contents of frequently consumed foods in Korea.

• Fire Science and Engineering
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• v.22 no.5
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• pp.90-98
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• 2008

There are diverse barriers such as limits to space, time, economy, technology, institution, and etc. in remodeling construction compared to new construction and it needs to overcome such limits. Consequently, for effective performance of construction, planning and application fit for remodeling characteristics shall be made available in time and various studies into remodeling for each construction category are necessary to achieve this. Taking these into account this study conducted research of the followings to draw out necessary steps for planning and application of fire protection facilities in remodeling, to overcome various barriers that may arise during any project operations, and to provide useful materials for construction of reasonable and effective fire protection system.

• Mycobiology
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• v.42 no.4
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• pp.339-345
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• 2014

During 2011~2013, a total of 729 samples for 19 types of medicinal plant were collected from Seoulyekryungsi in Seoul, Korea, and investigated for the presence of aflatoxins. The samples were analyzed using immunoaffinity column cleanup and high-performance liquid chromatography coupled to a fluorescence detector after post-column derivatization. Aflatoxins were found in 124 out of the 729 analyzed samples: 65 containing aflatoxin B1 (AFB1), 24 with aflatoxin B2 (AFB2), 15 with aflatoxin G1 (AFG1), and 20 samples with aflatoxin G2 (AFG2). The ranges for positive samples were $0.1{\sim}404.7{\mu}g/kg$ for AFB1, $0.1{\sim}10.0{\mu}g/kg$ for AFB2, $0.1{\sim}635.3{\mu}g/kg$ for AFG1, $0.1{\sim}182.5{\mu}g/kg$ for AFG2, and $0.1{\sim}1,043.9{\mu}g/kg$ for total aflatoxins. Most of the medicinal plant samples (721, 98.9%) were below legal limits, but 8 samples exceeded the legal limits of 10 and $15{\mu}g/kg$ established by the Korean standard for AFB1 and total aflatoxins (the sum of AFB1, AFB2, AFG1 and AFG2), respectively.

• YAKHAK HOEJI
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• v.36 no.5
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• pp.506-511
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• 1992

The Prostaglandins were derivatized rapidly with monodansyl cadaverine as a fluorophore in mild conditions. The carboxylic moiety of prostaglandins was activated with diethyl phosphorocyanidate and successively coupled with fluorophore in dimethylformamide at room temperature. The labeling yield was reached about 95% at 15 min using arachidic acid $(C_{20:0})$ as a test sample. This derivative showed constant fluorescent intensity at $4^{\circ}C$ for 180 days. The derivatives of prostaglandins were shown high solvent selectivity with tetrahydrofuran in reversed-phase column. therefore, these derivatives could be successfully separated on YMC pack A-212(S-5 120A C8) column in tetrahydrofuran-based eluents. The detection limits of these derivatives was ca. 500 fmol and determination limits was ca. 5 pmol as injected amount in fluorescent detection $({\lambda}ex.\;340\;nm,\;{\lambda}em.\;520\;nm)$. In this method, the ranges of recovery and coefficient of variation were $93.6{\sim}102.7%$ and $4.3{\sim}5.8%$, respectively.

• Journal of Preventive Veterinary Medicine
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• v.42 no.4
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• pp.171-176
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• 2018

A study of the tissue depletion of florfenicol (FFC) administered orally to pigs at a dose of 0.05 kg/ton feed for 7 days was performed. Sixteen healthy cross swine were administered with FFC. Four treated animals were arbitrarily selected to be sacrificed 1, 3 and 5 days after the end of treatment. FFC residue concentrations in muscle, liver, kidney, and fat were determined using high-performance liquid chromatography (HPLC) with ultraviolet photometric detector at 230 nm. The correlation coefficient ($R^2$) of the calibration curve for florfenicol amine (FFCa) was > 0.997 and the limits of detection and quantification were 0.012 and $0.040{\mu}g/mL$, respectively. Recovery rates in swine edible tissues ranged from 79.1 to 93.5%. In the FFC-treated group, FFC residues at 3 days post-treatment were below the maximum residue limits (MRLs) in muscle, kidney and fat, and those at 5 days post-administration were below the MRLs in all edible tissues. These results suggest that the withdrawal period of FFC after the drug treatment might be 5 days, which is a sufficient amount of time for reduction of the FFC residues below the MRLs in all edible tissues.