• Title/Summary/Keyword: Patterns

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Novel Role of Dipterocarpus tuberculatus Roxb. as a Lipogenesis Inhibitor and Lipolysis Stimulator in 3T3-L1 Adipocytes (3T3-L1 지방세포에서 lipogenesis 저해제와 lipolysis 촉진제로서 Dipterocarpus tuberculatus Roxb.의 새로운 역할)

  • Su Jin, Lee;Ji Eun, Kim;Yun Ju, Choi;You Jeong, Jin;Yu Jeong, Roh;AYun, Seol;Hee Jin, Song;Dae Youn, Hwang
    • Journal of Life Science
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    • v.32 no.11
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    • pp.855-864
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    • 2022
  • The pharmacological efficacy of Dipterocarpus tuberculatus Roxb. has been verified in only several fields including photoaging, inflammation, hepatotoxicity, acute gastritis and osseointegration. To identify the novel functions of Dipterocarpus tuberculatus Roxb. on anti-obesity, inhibitory effect on lipid accumulation and stimulatory effect on lipolysis were investigated in MDI (3-isobutyl-1-methyl-xanthine, dexamethasone, and insulin) stimulated 3T3-L1 adipocytes treated with methanol extracts of Dipterocarpus tuberculatus Roxb. (MED). Lipogenic targets, including lipid accumulation, level of lipogenic transcription factors, and expression of lipogenic regulators, were downregulated in MDI-stimulated 3T3-L1 adipocytes treated with MED without any significant cytotoxicity. Also, MED treatment inhibited the mRNA levels of adipogenic targets including peroxisome proliferator-activated receptor (PPAR)γ and CCAAT-enhancer binding protein (C/EBP) α, as well as lipogeic targets including adipocyte fatty acid binding protein 2 (aP2) and fatty acid synthetase (FAS) in MDI-stimulated 3T3-L1 adipocytes. A similar decrease patterns were detected in Oil red O stained lipid droplets of MED treated MDI-stimulated 3T3-L1 adipocytes. Furthermore, several lipolytic targets, such as cAMP concentration, concentration of free glycerol, expression level of lipases, including ATGL, perilipin and HSL, were upregulated in MDI-stimulated 3T3-L1 adipocytes treated with MED. These results show that MED has a novel role as a lipogenesis inhibitor and lipolysis stimulator in MDI-stimulated 3T3-L1 adipocytes.

Estimating the water supply capacity of Hwacheon reservoir for multi-purpose utilization (다목적 활용을 위한 화천댐 용수공급능력 평가 연구)

  • Lee, Eunkyung;Lee, Seonmi;Ji, Jungwon;Yi, Jaeeung;Jung, Soonchan
    • Journal of Korea Water Resources Association
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    • v.55 no.6
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    • pp.437-446
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    • 2022
  • In April 2020, the Korean government decided to operate the Hwacheon reservoir, a hydropower reservoir to supply water, and it is currently under pilot operation. Through the pilot operation, the Hwacheon reservoir is the first among the hydropower reservoirs in Korea to make a constant release for downstream water supply. In this study, the water supply capacity of the Hwacheon reservoir was estimated using the inflow data of the Hwacheon reservoir. A simulation model was developed to calculate the water supply that satisfies both the monthly water supply reliability of 95% and the annual water supply reliability of 95%. An optimization model was also developed to evaluate the water supply capacity of the Hwacheon reservoir. The inflow data used as input data for the model was modified in two ways in consideration of the impact of the Imnam reservoir. Calculating the water supply for the Hwacheon reservoir using the two modified inflows is as follows. The water supply that satisfies 95% of the monthly water supply reliability is 26.9 m3/sec and 24.1 m3/sec. And the water supply that satisfies 95% of the annual water supply reliability is 23.9 m3/sec and 22.2 m3/sec. Hwacheon reservoir has a maximum annual water supply of 777 MCM (Million Cubic Meter) without failure in the water supply. The Hwacheon reservoir can supply 704 MCM of water per year, considering the past monthly power generation and discharge patterns. If the Hwacheon reservoir performs a routine operation utilizing its water supply capacity, it can contribute to stabilizing the water supply during dry seasons in the Han River Basin.

The Cases and Patterns of Bronze Mirrors Enshrined in Pagodas during the Five Dynasties and the Song Dynasty (중국 오대~송대 탑 내 동경 봉안 사례와 양상)

  • CHOI, Juyeon
    • Korean Journal of Heritage: History & Science
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    • v.55 no.2
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    • pp.24-48
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    • 2022
  • Bronze mirrors found in pagodas were regarded as simple offerings and thus have received little attention in studies. Furthermore, the few studies on bronze mirrors enshrined in pagodas have focused on the line-engraved mirrors found in the pagodas of the Kingdom of Wuyue; therefore, it is difficult to understand the general characteristics of the bronze mirrors enshrined in the pagodas. This study assumes that the bronze mirrors found in many pagodas in the Kingdom of Wuyue and the Song dynasty were enshrined for a specific purpose. To explore this assumption and accurately understand the artifacts, this study focuses on the location and method of enshrinement. The number of bronze mirrors enshrined in pagodas increased during the Kingdom of Wuyue, with the mirrors expressing statues and inscriptions related to Buddhism rather than being simple offerings. This shows that the purpose of the bronze mirror changed. The influence of the Kingdom of Wuyue continued during the Song dynasty; however, the pattern of bronze mirror enshrinement changed due to the culture and social atmosphere of the time. The most common types of enshrined bronze mirrors were plain, and bronze mirrors from the Dang dynasty were also used consistently. Plain bronze mirrors were used more frequently in this period despite the lingering influence of the Kingdom of Wuyue because it was less laborious to engrave images and inscriptions such as the inscription of Buddha. Additionally, bronze mirrors were valued during this period because of the attention toward the imitation of the archaic bronze(仿古銅器) of the Song dynasty and the influence of the emperor. Moreover, it is believed that bronze mirrors were enshrined in pagodas as offerings as they were deemed valuable at the time. There was a change in the method of enshrining bronze mirrors in pagodas during the Kingdom of Wuyue and the Song dynasty. During this time, bronze mirrors that were positioned on the floor or in iron boxes were intentionally attached to walls or hung from the ceiling. This method was largely divided into two types: attaching to walls or the ceiling(嵌入鏡) and hanging from the ceiling(懸鏡). A typical example of hanging a bronze mirror from the ceiling can be seen in the Jingzhisa Temple Pagoda, and Teng County's Fushengsa Temple Pagoda contains an example of attaching a bronze mirror to the ceiling. The methods of hanging or attaching bronze mirrors to the ceiling were closely related to the methods employed in Chinese tombs. Song dynasty burial chambers had a high and wide structure, so to defend against evil spirits(辟邪用), bronze mirrors were used to protect the burial rooms. Bronze mirrors were, therefore, placed high to illuminate the burial room. This was achieved in the ways mentioned above. As underground chambers became wider and higher, mirrors also protected the important areas of the chambers and illuminated the interiors. Thus, it is believed that the methods of enshrining bronze mirrors in the pagodas during the Kingdom of Wuyue and the Song dynasty arose from the method of enshrining bronze mirrors in tombs at the time. Thereafter, pagodas, such as the Miaojuesa Temple Pagoda, in which the placement of a bronze mirror was actively considered from the design stage were constructed.

Developmental Characteristics of Zophobas atratus (Coleoptera: Tenebrionidae) at Varing Temperatures (온도에 따른 아메리카왕거저리(Zophobas atratus)의 발육 특성)

  • Kwak, Kyu-Won;Kim, Sun Young;Lee, Kyeong Yong;Yoon, Hyung Joo
    • Korean journal of applied entomology
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    • v.61 no.2
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    • pp.357-368
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    • 2022
  • We investigated the developmental characteristics of super mealworm (Coleoptera: Tenebrionidae) at four different temperatures (25℃, 27℃, 30℃, and 33℃). The rearing conditions were 9L/15D, 65% RH, and 1,330 to 1,800 lux with wheat bran. The length of developmental period of 1 to 18 instars at each temperature showed that 30℃ was the shortest at 120.0±5.8 days, compared to that at 27℃ (132.6±10.7 days), 33℃ (136.5±9.2 days), and 25℃ (156.7±7.5 days). The larval developmental period was statistically significantly longer at 25℃, 27℃, and 30℃ compared to the length at 33℃. However, the death rate of larvae at 33℃ was 2.7-3.3 times higher than the rate at other temperatures. Body weight was heaviest at 30℃ followed by 27℃, 33℃, and 25℃. The patterns of head capsule, body capsule, and body length were similar to that of body weight. Regression analyses of developmental period, larval body weight, and length according to temperature revealed 29-30℃ as the most suitable temperature. The prepupa rate was 43.1% in 17 instars, 30.3% in 18 instars, 15.4% in 16 instars, 7.1% in 19 instars, 2.2% in 15 instars, and 1.9% in 20 instars, accounting for 88.8% in 16-18 instars. Prepupal period was longer at lower temperatures. For the average prepupal period of 15-18 instars, prepupa time was 18.8±1.9 days at 27℃, 18.8±2.3 days at 30℃, 23.0±2.4 days at 33℃, and 23.1±2.9 days at 25℃. The average pupal period of females and males was 11.1±2.2 and 11.6±2.4 days, respectively. The data indicate that the most suitable rearing temperature of super mealworm was 30℃.

A preliminary assessment of high-spatial-resolution satellite rainfall estimation from SAR Sentinel-1 over the central region of South Korea (한반도 중부지역에서의 SAR Sentinel-1 위성강우량 추정에 관한 예비평가)

  • Nguyen, Hoang Hai;Jung, Woosung;Lee, Dalgeun;Shin, Daeyun
    • Journal of Korea Water Resources Association
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    • v.55 no.6
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    • pp.393-404
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    • 2022
  • Reliable terrestrial rainfall observations from satellites at finer spatial resolution are essential for urban hydrological and microscale agricultural demands. Although various traditional "top-down" approach-based satellite rainfall products were widely used, they are limited in spatial resolution. This study aims to assess the potential of a novel "bottom-up" approach for rainfall estimation, the parameterized SM2RAIN model, applied to the C-band SAR Sentinel-1 satellite data (SM2RAIN-S1), to generate high-spatial-resolution terrestrial rainfall estimates (0.01° grid/6-day) over Central South Korea. Its performance was evaluated for both spatial and temporal variability using the respective rainfall data from a conventional reanalysis product and rain gauge network for a 1-year period over two different sub-regions in Central South Korea-the mixed forest-dominated, middle sub-region and cropland-dominated, west coast sub-region. Evaluation results indicated that the SM2RAIN-S1 product can capture general rainfall patterns in Central South Korea, and hold potential for high-spatial-resolution rainfall measurement over the local scale with different land covers, while less biased rainfall estimates against rain gauge observations were provided. Moreover, the SM2RAIN-S1 rainfall product was better in mixed forests considering the Pearson's correlation coefficient (R = 0.69), implying the suitability of 6-day SM2RAIN-S1 data in capturing the temporal dynamics of soil moisture and rainfall in mixed forests. However, in terms of RMSE and Bias, better performance was obtained with the SM2RAIN-S1 rainfall product over croplands rather than mixed forests, indicating that larger errors induced by high evapotranspiration losses (especially in mixed forests) need to be included in further improvement of the SM2RAIN.

Comparative Analysis of Mitochondrial Genomes of the Genus Sebastes (Scorpaeniformes, Sebastidae) Inhabiting the Middle East Sea, Korea (한국 동해 중부해역에 서식하는 볼락속(Sebastes) 어류의 미토콘드리아 유전체 비교분석)

  • Jang, Yo-Soon;Hwang, Sun Wan;Lee, Eun Kyung;Kim, Sung
    • Korean Journal of Ichthyology
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    • v.33 no.4
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    • pp.226-239
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    • 2021
  • Sebastes minor, Sebastes trivittatus, Sebastes owstoni, and Sebastes steindachneri are indigenous fish species inhabiting the central part of the East Sea, Korea. In order to understand the molecular evolution of these four rockfishes, we sequenced the complete mitochondrial genomes (mitogenomes) of S. minor and S. trivittatus. To further analyze the phylogeny of Sebastes species, the mitogenomes of 16 rockfishes were comparatively investigated. The complete mitochondrial DNA (mtDNA) nucleotide sequences of S. minor and S. trivittatus were 16,408 bp and 16,409 bp in length, respectively. A total of 37 genes were found in mtDNA of S. minor and S. trivittatus, including 13 protein-coding genes, 2 ribosomal RNA genes, and 22 transfer RNA genes, which exhibited similar characters with other Sebastes species in the East Sea, Korea. In addition, we detected a conserved motif "ATGTA" in the control region of the four Sebastes species, but no tandem repeat units. Comparative analyses of the congeneric mitochondrial genomes were performed, which showed that control regions were more variable than the concatenated protein-coding genes. As a result of analysing phylogenetic relationships of four Sebastes species by using concatenated nucleotide sequences of 13 protein-coding genes, S. minor, S. trivittatus, S. owstoni and S. steindachneri were clustered into three clades. The phylogenetic tree exhibited that S. minor and S. steindachneri shared a closer relationship, whereas S. trivittatus and S. vulpes formed another distinct clade. Our results contribute to a better understanding of evolutionary patterns of Sebastes species inhabiting the middle East Sea, Korea.

Initial Evaluation using Geochemical Data to infer Tectonic Setting of Mt. Baekdu/Changbaishan Volcano (백두산 화산의 지체구조 추론을 위한 지구화학적 데이터를 이용한 기초 평가)

  • Yun, Sung-Hyo;Chang, Cheolwoo;Pan, Bo
    • Journal of the Korean earth science society
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    • v.43 no.1
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    • pp.128-139
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    • 2022
  • This study aimed to investigate the tectonic setting of the volcanic edifice at Mt. Baekdu by analyzing petrochemical characteristics of Holocene felsic volcanic rocks distributed in the Baekdusan stratovolcano edifice and summit of the Cheonji caldera rim, as well as Pleistocene mafic rocks of the Gaema lava plateau and Changbaishan shield volcano edifice. During the early eruption phases, mafic eruption materials, with composition ranging from alkali basalt to trachybasalt, or from subalkaline (tholeiitic) basalt to basaltic andesite formed the Gaema lava plateau and Changbaishan shield volcanic edifice, whereas the Baekdusan stratovolcano edifice and Holocene tephra deposits near the summit of the Cheonji caldera comprises trachytic and rhyolitic compositions. Analysis results revealed bimodal compositions with a lack of 54-62 SiO2, between the felsic and mafic volcanic rocks. This suggested that magmatic processes occurred at the locations of extensional tectonic settings in the crust. Mafic volcanic rocks were plotted in the field of within-plate volcanic zones or between within-plate alkaline and tholeiite zones on the tectonic discrimination diagram, and it was in good agreement with the results of the TAS diagram. Felsic volcanic rocks were plotted in the field of within-plate granite tectonic settings on discrimination diagrams of granitic rocks. None of the results were plotted in the field of arc islands or continental margin arcs. The primitive mantle-normalized spider diagram did not show negative (-) anomalies of Nb and Ti, which are distinctive characteristics of subduction-related volcanic rocks, but exhibited similar patterns of ocean island basalt. Trace element compositions showed no evidence of, magmatic processes related to subduction zones, indicating that the magmatic processes forming the Baekdusan volcanic field occurred in an intraplate environment. The distribution of shallow earthquakes in this region supports the results. The volcanic rocks of the Baekdusan volcanic field are interpreted as the result of intraplate volcanism originating from the upwelling of mantle material during the Cenozoic era.

Prevalence of Tarsal Coalition in the Korean Population: A Single Institution-Based Study (한국인의 족근골 유합의 유병률: 병원 내원 환자에 대한 연구)

  • Kim, Tae Yong;Yoon, So Hee;Ko, Jung Hoon;Lee, Tae Ho;Yi, Seung Rim
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.4
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    • pp.324-330
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    • 2020
  • Purpose: Korean studies on the prevalence of a tarsal coalition are quite rare, and there are very few reports on the prevalence of multiple tarsal coalitions among adults in the foreign literature. Therefore, this study examined the characteristics and prevalence of tarsal coalition in the Korean population based on imaging tests. Materials and Methods: The prevalence of tarsal coalition and its anatomical location and histological classification were reviewed retrospectively among 4,711 patients (4,454 males and 257 females) with an ankle sprain or ankle fracture who underwent foot and ankle computed tomography and magnetic resonance imaging between March 2009 and February 2019 at the authors' institution. Results: Over a period of 10 years, 78 patients (1.7%) had a tarsal coalition, among whom 53 patients (67.9%) had an isolated tarsal coalition and 25 patients (32.1%) had multiple tarsal coalitions. Regarding the anatomical location, a talocalcaneal coalition was the most common type in both isolated (31 patients, 37 cases [62.7%]) and multiple (22 patients, 23 cases [45.1%]) tarsal coalitions. In the isolated coalition group, the second-most common type was calcaneonavicular coalition (10 patients, 16.9%), followed by naviculocuneiform (nine patients, 15.3%) and cuboidonavicular coalitions (three patients, 5.1%). In the multiple coalition group, the second-most common coalition type was calcaneonavicular coalition (14 patients, 14 cases [27.5%]), followed by talonavicular coalition (six patients, six cases [11.8%]). From a total of 60 cases of talocalcaneal coalition, 24 cases (40.0%) were in the posterior facet, 18 cases (30.0%) in the middle facet, and four cases (6.7%) in the anterior facet. Regarding the histological classification, cartilaginous coalition was the most common in both single (32 patients, 35 cases [59.3%]) and multiple (20 patients, 37 cases [72.5%]) coalition groups. Conclusion: The present study found that talocalcaneal coalition was the most common type of tarsal coalition. In contrast to previous reports that a talocalcaneal coalition generally occurs in the middle facet, it was usually observed in the posterior facet in the present study. In addition, although multiple tarsal coalitions have been reported to be quite rare, this study confirmed that they are not rare and can occur in a range of patterns.

Geomagnetic Paleosecular Variation in the Korean Peninsula during the First Six Centuries (기원후 600년간 한반도 지구 자기장 고영년변화)

  • Park, Jong kyu;Park, Yong-Hee
    • The Journal of Engineering Geology
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    • v.32 no.4
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    • pp.611-625
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    • 2022
  • One of the applications of geomagnetic paleo-secular variation (PSV) is the age dating of archeological remains (i.e., the archeomagnetic dating technique). This application requires the local model of PSV that reflects non-dipole fields with regional differences. Until now, the tentative Korean paleosecular variation (t-KPSV) calculated based on JPSV (SW Japanese PSV) has been applied as a reference curve for individual archeomagnetic directions in Korea. However, it is less reliable due to regional differences in the non-dipole magnetic field. Here, we present PSV curves for AD 1 to 600, corresponding to the Korean Three Kingdoms (including the Proto Three Kingdoms) Period, using the results of archeomagnetic studies in the Korean Peninsula and published research data. Then we compare our PSV with the global geomagnetic prediction model and t-KPSV. A total of 49 reliable archeomagnetic directional data from 16 regions were compiled for our PSV. In detail, each data showed statistical consistency (N > 6, 𝛼95 < 7.8°, and k > 57.8) and had radiocarbon or archeological ages in the range of AD 1 to 600 years with less than ±200 years error range. The compiled PSV for the initial six centuries (KPSV0.6k) showed declination and inclination in the range of 341.7° to 20.1° and 43.5° to 60.3°, respectively. Compared to the t-KPSV, our curve revealed different variation patterns both in declination and inclination. On the other hand, KPSV0.6k and global geomagnetic prediction models (ARCH3K.1, CALS3K.4, and SED3K.1) revealed consistent variation trends during the first six centennials. In particular, the ARCH3K.1 showed the best fitting with our KPSV0.6k. These results indicate that contribution of the non-dipole field to Korea and Japan is quite different, despite their geographical proximity. Moreover, the compilation of archeomagnetic data from the Korea territory is essential to build a reliable PSV curve for an age dating tool. Lastly, we double-check the reliability of our KPSV0.6k by showing a good fitting of newly acquired age-controlled archeomagnetic data on our curve.

The Relationship between Subjective Socioeconomic Status, Age and Perception of Justice: Focusing on the Moderation Effect of Age (주관적 사회경제적 지위, 연령, 공정성 인식 간의 관계: 연령의 조절효과를 중심으로)

  • Joeng, Ju-Ri;Lee, Ji Hae
    • Korean Journal of Culture and Social Issue
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    • v.28 no.2
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    • pp.219-239
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    • 2022
  • The study investigated the relationship between subjective socioeconomic status (SES) of 508 Korean adults and their perception of justice (distributive and procedural justice for self and general others), and verified whether there is a moderating effect of age (20s versus 30s and over). A self-report survey on SES and perception of justice was conducted. Then, using the SPSS 27 and PROCESS Macro 4.0 program, a correlation analysis looking into the relationship among the study variables was performed along with the ANOVAs comparing the mean differences of study across age-groups to support the group division criteria. Next, a moderation analysis was conducted. The main results of this study are as follows. First, the participants' SES showed a positive relationship with all sub-factors of justice perception and a negative relationship with age. Second, age had a inverse relationship on distributive justice for self and general others, and procedural justice for self, but a non significant relationship on procedural justice for general others. Third, when looking into the mean differences of the research variables according to age, the 20s had different characteristics compared to the 30s and over. In comparison, there were no significant differences within the 30s and over group. Fourth, the moderating effect of age in the relationship between subjective SES and perception of justice was positively significant in the case of distributive justice for self and procedural justice for general others. In the case of distributive justice for self, the positive slope of the graph in which subjective SES predicts distributive fairness for self was steeper in the 30s and older group compared to the 20s. Regarding the procedural justice for general others, subjective SES was not a significant predictor in the 20s group. However, SES positively predicted procedural justice in the 30s and older group. This study is meaningful since it suggested age differences in subjective SES and perceptions of justice by revealing the different relationship patterns of subjective SES and perception of justice according to age.