• 한국대기환경학회지
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• 제21권6호
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• pp.613-624
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• 2005

In this study, we investigated the characteristic of volatile organic compounds (VOCs) concentrations in Shiwha area, which were measured using the Open-path FTIR Gas Analyzer. The passive samplers were set for a certain period of time to obtain the average concentration of toluene, ethylbenzene, o-xylene and styrene. In addition, VOCs concentration contour maps were constructed using the Tecplot program to illustrate the VOCs concentration distribution. The residential area showed higher concentrations than the industrial area. And the summer had higher concentration value than the winter. Also, we confirmed that the VOCs concentrations ranged from 2 to several tens ppb in the vicinity of an industry than diffused VOC concentration, whereas those ranged from 0 to 5 ppb in most other areas. It was conferred that the wind change with seasons significantly affects the distribution of VOCs concentrations such as a northwesterly wind in the winter or a southwestern wind in the summer.

• ETRI Journal
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• 제35권6호
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• pp.1011-1020
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• 2013

In this paper, we present a method for obtaining a high-quality 3D depth. The advantages of active pattern projection and passive stereo matching are combined and a system is established. A diffractive optical element (DOE) is developed to project the active pattern. Cross guidance (CG) and auto guidance (AG) are proposed to perform the passive stereo matching in a stereo image in which a DOE pattern is projected. When obtaining the image, the CG emits a DOE pattern periodically and consecutively receives the original and pattern images. In addition, stereo matching is performed using these images. The AG projects the DOE pattern continuously. It conducts cost aggregation, and the image is restored through the process of removing the pattern from the pattern image. The ground truth is generated to estimate the optimal parameter among various stereo matching algorithms. Using the ground truth, the optimal parameter is estimated and the cost computation and aggregation algorithm are selected. The depth is calculated and bad-pixel errors make up 4.45% of the non-occlusion area.

• 한국해양공학회지
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• 제7권1호
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• pp.13-24
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• 1993

해양오염은 환경파괴의 주요 인자이다. 해양바닥에 가라않은 오염물질을 근본적으로 제거하는 문제와는 별도로, 파동(wave)에 의해 그것이 자동적으로확산될 수가 있다. 파문(ripple)으로 덮혀진 해저(sea bottom)에서 표면의 중력파에 의한 물의 수평방향 요동운동은 와류(vrotices)를 발생시칸다. 이런한 유동장은 해저 침전물을 부유시켜 멀리까지 화가신시키는 작용을 한다.파문주위의 유동장을 살펴보면 모서리(crest)에서 발생된 와류로 인해 정상유동성분이 존재하며 이런한 정상유동은 파문의 주기적 형상으로인해 다분히 순환적이다. 이ㅔ 파동에 의한 요동운동이 가세하면 Taylor 와류와 같은 효과를 보여 줄 것이다. 해저부근에서의 이러한 확산효과를 보기 위하여, 해양유동을 단순화하여 최근 널리 이용되고 있는 혼돈이론을 가미시켰다. 아주 단순한 유동이라도 복잡한 입자의 궤적을 나타내며 입자의 확산과 연관됨을 수치해석을 이용하여 보여준다.

• 약학회지
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• 제56권1호
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• pp.26-34
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• 2012

Mast cells play an important role in early and late phase allergic reactions through allergen and IgE-dependent release of histamine, proteases, prostaglandins, and several multifunctional cytokines. In this study, we investigated whether Cudrania tricuspidata extract (CTE) suppresses IgE-mediated allergic responses in mast cells, an allergic animal model, and its mechanism of action in mast cells. We found that CTE inhibited IgE-mediated degranulation and cytokine production in rat basophilic leukemia (RBL)-2H3 mast cells and bone marrow-derived mast cells (BMMC), as well as passive cutaneous anaphylaxis (PCA) in mice. With regard to its mechanism of action, CTE suppressed the activating phosphorylation of spleen tyrosine kinase (Syk), a key enzyme in mast cell signaling processes and that of LAT, a downstream adaptor molecule of Syk in $Fc{\varepsilon}RI$-mediated signal pathways. CTE also suppressed the activating phosphorylation of mitogen-activated protein (MAP) kinases and Akt. The present results strongly suggest that the anti-allergic activity of CTE is mediated through inhibiting degranulation and allergic cytokine secretion by inhibition of Syk kinase in mast cells. Therefore, CTE may be useful for the treatment of allergic diseases.

• 한국식품위생안전성학회지
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• 제29권4호
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• pp.356-362
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• 2014

Allergic diseases have increased rapidly over the past decades, affecting an estimated 20~30% of the population in developed countries. In this study, we investigated whether or not a typical costal sand dune plant Carex pumila (CPE) suppresses the activation of mast cells and IgE-mediated allergic response in vitro and in vivo. As the results, the extract of Carex pumila inhibited antigen-stimulated degranulation in RBL-2H3 cells and Bone marrow-derived mast cells (BMMCs), and IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. CPE also suppressed the production of pro-inflammatory cytokines, TNF-${\alpha}$ and IL-4, in antigen-stimulated mast cells. As its mechanism of action, CPE inhibited the activation of Syk in $Fc{\varepsilon}RI$-mediated signalling pathway, and that of LAT, a downstream adaptor molecule of Syk, in a dose-dependent manner. CPE also suppressed the activation of mitogen-activated protein (MAP) kinases, p38, ERK1/2, JNK, and Akt. Altogether, CPE inhibited mast cell activation and IgE-mediated allergic response by antigen through suppressing the activation of Syk. These results suggest that CPE may be useful for the treatment of allergic diseases.

• 생약학회지
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• 제49권4호
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• pp.298-304
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• 2018

Malus sieboldii is a dicotyledonous plant that grows widely in Jeju Island and Ganghwa Island in Korea. Malus sieboldii has been known as a detoxifying and antioxidant plant, but study on allergic diseases is not known. In this study, we investigated the effect of Malus sieboldii extract (MSE) on the activation of mast cells, which is well known to be a critical causative cell to induce allergic diseases. As a result of our experiments, MSE inhibited the degranulation and inflammatory cytokine secretion from mast cells by antigen stimulation. As the mechanism of MSE in mast cells, it inhibited the activation of Syk kinase, a essential signaling protein activated by antigen, and further inhibited activation of $PLC{\gamma}$ and MAP kinase(P38, ERK1/2, and JNK). Furthermore, in vivo animal studies showed that MSE significantly inhibited IgE-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis in a dose-dependent manner. Taken together, the results of this study showed for the first time that MSE inhibited IgE-mediated allergic responses by suppressing Syk kinase in mast cells. Therefore, it could be considered that MSE is worth developing as an anti-allergic material.

• 생약학회지
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• 제51권4호
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• pp.317-324
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• 2020

Mast cells play a key role in IgE-mediated allergic response. We investigated whether Swertia pseudochinensis Hara extract (SPE) inhibits IgE-mediated allergic response in mast cells and an allergic animal model. Additionally, we explored SPE's mechanism of action in mast cells. Our results showed that SPE inhibited both antigen-stimulated degranulation and the production of TNF-α and IL-4 in bone marrow-derived mast cells (BMMCs) and rat basophilic leukemia (RBL)-2H3 cells. SPE also suppressed allergic response in IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. As for the mechanism of action of SPE in mast cells, it inhibited the activation of Syk kinase, a critical signaling protein in the FcεRI-mediated signaling pathway, and also the activation of LAT, a downstream adaptor protein of Syk. We further observed the reduced activation of mitogen-activated protein (MAP) kinases (P38, ERK1/2, and JNK) and Akt in mast cells. Our results described for the first time that SPE has an anti-allergic effect by suppressing mast cells through the inhibition of Syk kinase. Therefore, SPE may be useful for the treatment of type I allergic diseases.

• 한국정밀공학회지
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• 제26권6호
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• pp.81-89
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• 2009

Dancer systems are typical equipment for attenuation of tension disturbances. Lately, demands for high speed roll-to-roll machines are rising but it is prior to attenuate the tension variation on the web entering into the printing zone to achieve the speed increment. Maintaining a constant tension before the first printing cylinder is the key of high speed, high quality printing. Dancer has been researched in two ways, whether it is controlled or not. The first one is active dancer and the other one is passive dancer. In the active dancer, a position of idle roll of dancer is measured and the roll is moved by external hydraulic cylinder to control tension disturbances. While the passive one composed with spring, damper and idle roll has no external actuator to position the idle roll. The tension disturbance causes movement of dancer roll and the displacement of the roll regulates the tension variation. On the other hand a composite type of dancer is applied for roll-to-roll printing machines. It has same apparatus as passive dancer. The displacement of roll is measured and front(or rear) driven roller is controlled to position the roll. In this paper, it is presented an analysis of pendulum dancer including position feedback PI control and logic for PI gain tuning in roll-to-roll machines. Pole-zero map and root locus with varying system parameters gives a design method for control of the dancer.

• Nuclear Engineering and Technology
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• 제52권1호
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• pp.37-50
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• 2020

A passive containment cooling system (PCCS) has been developed as advanced safety feature for innovative power reactor (iPOWER). Passive systems are inherently less stable than active systems and the PCCS encountered the flashing-induced instability previously identified. The objective of this study is to develop stability maps for flashing-induced instability using MARS (Multi-dimensional Analysis of Reactor Safety) code. Firstly, we conducted a series of sensitivity analysis to see the effects of time step size, nodalization, and alternative MARS user options on the onset of flashing-induced instability. The riser nodalization strongly affects the prediction of flashing in a long riser of the PCCS, while time step size and alternative user options do not. Based on the sensitivity analysis, a standard input and an analysis methodology were set up to develop the stability maps of PCCS. We found out that the calculated equilibrium quality at the exit of the riser as a stability boundary above 5 kW/㎡ was approximately 1.2%, which was in good agreement with Furuya's results. However, in case of a very low heat flux condition, the onset of instability occurred at the lower equilibrium quality. In addition, it was confirmed that inlet throttling reduces the unstable region.

• 대한기계학회논문집A
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• 제25권12호
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• pp.2030-2039
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• 2001

Recently, various inpipe inspection robots are developed and its effective values are increased in industrial use. However, it is so difficult to make a inpipe inspection robot system which has flexible mobility and accuracy of inspection in pipelines. Especially, it is very important to know the exact crack position. In this paper, we are to present a lately developed inpipe inspection robot system which can resolve the above Problems. The robot is configured as an articulated structure like a snake. Two active driving vehicles are located in front and rear of the inspection robot respectively and passive modules such as a nondestructive testing module and a control module are chained between the active vehicles. Special feature of the robot system is a ground interface, which is able to show informations of robot and pipelines. By using this, so called virtual map in this paper, user is able to know the pipelines'feature and crack position.