• 제목/요약/키워드: Partition coefficient

검색결과 287건 처리시간 0.028초

영역분할과 2차원 커브피팅 함수들을 이용하는 직선형 5공 압력프로브의 성능 평가 (The Performance Assessment of a Straight-Type Five-Hole Pressure Probe Using a Zone Partition and Two-Dimensional Curve-Fitting Functions)

  • 김장권;오석형
    • 동력기계공학회지
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    • 제18권1호
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    • pp.22-31
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    • 2014
  • This paper introduced the new calibration algorithm of a straight-type five-hole pressure probe necessary for calculating three-dimensional flow velocity components. The new velocity data reduction method using both a commercial two-dimensional curve-fitting program and the zone partition method of a calibration map was firstly introduced in this study. This new calibration method can be applied up to the wide flow angle of ${\pm}80^{\circ}$ despite of using a five-hole pressure probe because this data reduction method showed a comparatively good performance in calculating yaw and pitch angles from the calibration map.

극소수성 물질들에 대한 Slow-Stirring방법에 의한 옥탄올/물 분배계수 측정 (Slow-Stirring Methods for Determining the n-Octanol/Water Partition Coefficient(Pow) of Highly Hydrophobic Chemicals)

  • 장희라;이봉재;김균;김용화
    • Environmental Analysis Health and Toxicology
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    • 제20권4호통권51호
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    • pp.351-358
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    • 2005
  • The n -octanol/water partition coefficient (Pow) is one of the most important parameters employed for estimating a chemiral's environmental fate and toxicity. The shake-flask method, one direct experimental method, i.1 prone to experimental artifacts for highly hydrophobic compounds. Thus, a valid method for direct determination of the Pow of highly hydrophobic compounds is needed. The slow -stirring method has been demonstrated to provide reliable log Pow data to log Pow greater than 5. This study was performed to evaluate the accuracy of slow- stirring experiment for determination of log Pow, particularly for highly hydrophobic compounds. 1, 2, 3, 4-tetrachlorobenzene, hexachlorobezene, 2, 2', 3, 3', 5, 5', 6, 6'-octachlorobiphenyl, decachlorobiphenyl, and p, p'-DDT (4.5$\times$0.02, 5.41$\times$0.06, 7.26$\times$0.04, 7.87$\times$0.10, and 6.03$\times$0.06, respectively. The octanol/water partition coefficient by the slow-stirring method were very similar to the literature values. These results indicate that the slow- stirring method allows for reliable determination of log Pow of highly hydrophobic chemicals.

A PARTITION OF q-COMMUTING MATRIX

  • Eunmi Choi
    • East Asian mathematical journal
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    • 제39권3호
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    • pp.279-290
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    • 2023
  • We study divisibilities of elements in the q-commuting matrix C(q). We first make a coefficient matrix Ĉ of C(q) which is independent of q, study divisibilities over Ĉ and then retrieve our findings to C(q). Finally we partition the C(q) into 2 × 2 block matrices.

폴리우레탄 폼의 휘발성 유기화합물 확산 및 분배계수 산정 (The Determination of Diffusion and Partition Coefficients of PUF)

  • 박진수;;김신도;이희관;공부주
    • 한국대기환경학회지
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    • 제26권1호
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    • pp.77-84
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    • 2010
  • The diffusion and partition coefficients of polyurethane foam (PUF) are estimated using a microbalance experiment and small chamber test. The microbalance is used to measure sorption/desorption kinetics and equilibrium data. When the diffusion condition is controlled in the chamber of the sample, interactions between volatile organic compounds (VOCs) and PUF can lead to the estimation of a relatively homogenous rate of mass transfer in the interiors and surfaces of PUF. The estimates of the material/air partition coefficient (K) and the material-phase diffusion coefficient (D) are shown to be independent of the concentrations of VOCs. This approach, if applied to a diffusion-controlled or physically-based model, can facilitate more precise prediction of their source/sink behavior. Although further research and more rigorous validation is needed, an emission model applied with the diffusion and partition coefficients from this research holds promise for the improvement of reliability in predicting the behavior of VOCs emitted from porous building materials by D and K.

분할행렬법에 의한 다중 계단지형에서의 파랑변형 계산 (Computation of Wave Propagation over Multi-Step Topography by Partition Matrix Method)

  • 서승남
    • 대한토목학회논문집
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    • 제29권4B호
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    • pp.377-384
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    • 2009
  • 다중 계단으로 근사한 사주지형 위를 지나는 선형 파랑전파에 대한 고유함수 전개법에서 크기가 큰 행렬을 풀 때 계산시간을 상당히 단축하기 위하여 분할행렬법을 사용하여 반사율을 계산하였다. 본 모형에 10개의 억류파를 사용하여 현재까지 가장 정밀한 수치해를 구하였고 구한 반사율의 거동은 몇 경우에서 기존 결과와 다름을 보였다. 크기가 큰 행렬을 풀 때 본 분할행렬법의 계산시간과 기억용량은 여전히 커서 효율적인 방법에 대한 개발이 요구된다.

Production of Cyclodextrin Homologues Using Aqueous Two-Phase System

  • Chang, Woo-Jin;Koo, Yoon-Mo;Park, Sung-Sik
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제2권2호
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    • pp.97-100
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    • 1997
  • Cyclodxtrin homologues(CDs), produced by cyclodextrin glycosyltransferase(CGTase), were simultaneously partitioned in aqueous two-phase system(ATPS). Partition coefficients of CDs were measured in PEG/dextran systems. Phosphate, citrate, sulfate were tested as salt. ATPS of PEG/salt and PEG/dextran had the partition coefficients of the CDs, larger than unity. However, PEG/dextran system was observed better than PEG/salt as CGTase activity decreased sharply with salt concentration. Enzymatic rection occurred mainly in PEG-rich bottom phase because of the low partition coefficient of CGTase. The resulting CDs transferred to the PEG-rich top phase, obeying the diffusional partition. In the ATPS of 7% PEG(M.W.40, 000), 7mg/ml of CDs were obtained in top phase at 4.5 hours.

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유한열전도율(有限熱傳導率)의 격판(隔板)을 갖는 수직구형(垂直矩形) 밀폐공간(密閉空間)에서의 자연대류(自然對流)에 관(關)한 수치적(數値的) 연구(硏究) (A Computational Study of Natural Convection in Vertical Rectangular Enclosures with Partiton Plates of Finite Thermal Conductivity)

  • 박만흥;이재헌
    • 태양에너지
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    • 제2권1호
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    • pp.1-8
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    • 1982
  • A theoretical study by numerical method has been performed on the natural convection of an air contained in enclosures. The enclosures have rectangular cross section with one vertical wall heated and the other cooled, and with two horizontal partition plates of finite thermal conductivity. Steady two-dimensional flow was assumed. The computation was executed by means of the Implicit Alternating Direction (I.A.D) finite-difference method. Two partition plates of Aluminium whose thickness were 0.05mm was employed in computation. Isothemals, streamlines, local Nusselt numbers and mean Nusselt numbers were obtained for various Grashof numbers and aspect ratio and these results were compared with those in the case of the enclosure with two horizontal insulated plates. From the present results, the heat transfer in the case of partition plates was greater than that in the case of insulation. This study suggests a method to measure the overall heat-transfer of coefficient in double walls which supported by partition plates for insulative construction.

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Poly(ethylene glycol)-dextran 수용액 2상계에서 단백질 분획계수에 미치는 금속염의 효과 (Effects of Salts on the Partition of Proteins in Poly (ethylene glycol)-Dextran Aqueous Two Phase System)

  • 이삼빈;이철호
    • 한국식품과학회지
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    • 제19권2호
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    • pp.146-150
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    • 1987
  • 폴리에틸렌 글라이콜(PEG)-텍스트란 수용액 혼합물이 형성 하는 2상계에서 단백질의 분획현상에 대한 pH와 금속 이온의 영향을 검토하였다. PEG(5%)/dextran(9.5%)을 포함하는 5mM 인산 완충용액으로된 수용액 2상계에서 상층부와 하층부의 용적비를 1.0으로 하였을 때 분획계수는 각 단백질들의 등전점에서최소치를 나타 내었으며, pH가 등전점에서 벗어날 수록 단백질 분획계수는 증가하였다. 특히 pH11.0에서는 분획계수가 크게 증가하였으며 소수성이 가장 큰 BSA는 50배 ${\beta}-lactoglobulin$과 소수성이 비교적 적은 ovalbum은 각각 10배 증가하였다. 금속염 첨가는 pH3.0에서 단백질과 분획계수를 증가시키나. pH7.0과 pH11.0에서는 급격하게 감소시켰다. 단백질의 총전하가 양전하를 띠게 되는 pH3.0에서는 LiNa>K의 순으로 분획계수는 감소하였다.

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세파졸린의 경구투여를 위한 프로드럭의 개발 -세파졸린 에톡시카보널에칠 에스텔의 합성, 분배계수 및 항균력- (Development of Cefazolin Prodrug for Oral Administration -Synthesis, Partition Coefficient and Antibacterial Activity of Cefazolin Ethoxycarbonylethyl Ester-)

  • 정영국;범진필;최준식;이진환
    • Journal of Pharmaceutical Investigation
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    • 제24권4호
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    • pp.265-271
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    • 1994
  • Cefazolin ethoxycarbonylethyl ester (CFZ-ET) was synthesized to improve oral absorption and bioavailability of the parent drug by esterification of sodium cefazolin (CFZ-Na). The successful synthesis of CFZ-ET was identified with analysis of UV spectra, FT-lR spectra and NMR spectra. Partition coefficient studies showed that CFZ-ET was more lipophilic than CFZ-Na and the ester was hydrolyzed into the parent drug in vivo. Although CFZ-ET did not have antimicrobial activity in vitro, the plasma taken after the oral administration of CFZ-ET had antimicrobial activity. Based on above observations, CFZ-ET might be rapidly hydrolyzed to CFZ in the body. Therefore, it may be concluded that CFZ-ET could be a novel prodrug of CFZ which can improve the bioavailability of CFZ-Na.

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