• Mass Spectrometry Letters
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• v.11 no.1
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• pp.1-5
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• 2020

In this study, some of the recently reported data processing strategies were evaluated and modified based on their capabilities and a brief workflow for data mining was redefined for Q-TOF LC-MS based untargeted metabolomics. Commercial pooled human plasma samples were used for this purpose. An ultrafiltration procedure was applied on sample preparation. Sample set was analyzed through Q-TOF LC/MS. A C18 column (Agilent Zorbax 1.8 µM, 50 × 2.1 mm) was used for chromatographic separation. Raw chromatograms were processed using XCMS - R programming language edition and Isotopologue Parameter Optimization (IPO) was used to optimize XCMS parameters. The raw XCMS table was processed using MS Excel to find reliable and reproducible peaks. Totally 1650 reliable and reproducible potential metabolite peaks were found based on the data processing procedures given in this paper. The redefined dataset was upload into MetaboAnalyst platform and the identified metabolites were matched with 86 metabolic pathways. Thus, two list were obtained and presented in this study as supplement files. The first list is to present the retention times and m/z values of detected metabolite peaks. The second list is the metabolic pathways related with the identified metabolites. The briefly described data processing strategies and dataset presented in this study could be beneficial for the researchers working on untargeted metabolomics for processing their data and validating their results.

• Journal of the Korean Society for Precision Engineering
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• v.27 no.2
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• pp.13-19
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• 2010

Due to the rapid spread of mobile handheld devices, industrial demands for micro-scale holes with a diameter of even smaller than $10{\mu}m$ in sapphire/silicon wafers have been increasing. Holes in sapphire wafers are for heat dissipation from LEDs; and those in silicon wafers for interlayer communication in three-dimensional integrated circuit (IC). We have developed a sapphire wafer driller equipped with a 532nm laser in which a cooling chuck is employed to minimize local heat accumulation in wafer. Through the optimization of process parameters (pulse energy, repetition rate, number of pulses), quality holes with a diameter of $30{\mu}m$ and a depth of $100{\mu}m$ can be drilled at a rate of 30holes/sec. We also have developed a silicon wafer driller equipped with a 355nm laser. It is able to drill quality through-holes of $15{\mu}m$ in diameter and $150{\mu}m$ in depth at a rate of 100holes/sec.

• Transactions of Materials Processing
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• v.8 no.5
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• pp.507-519
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• 1999

An approach using the energy method has veen proposed for the analysis of cone spinning having the complicated deformation modes mixed by shear and normal deformation. In the proposed method, the corresponding solution is found through optimization of the total energy dissipation with respect to the parameters assumed by the velocity field defined as the variation of the length in longitudinal direction. The sheet blank is divided into three layers to consider the bending effect and the energy dissipated by shear deformation is superposed to the energy consumption due to normal deformation related with the shrinking deformation is superposed to the energy consumption due to normal deformation related with the shrinking deformation of axi-symmetric sheet element for the evaluation of total deformation energy. In order to check the validity of the proposed method, the complex spinning for making the conical cup is analyzed and the computed results are compared with the experimental results. In comparison of the computed results with existing experimental results,, the good agreement is obtained for the variation of outer radius and the distribution of thickness, and it has thus been shown that the present approach is applicable to the analysis of complex spinning.

• Journal of Welding and Joining
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• v.33 no.1
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• pp.54-60
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• 2015

Laser-arc hybrid welding has been considered as an effective pipe girth welding process since early 2000's. Tolerance for fit-up offsets such as gap and edge misalignment is one of most important requirements in pipe girth laser-arc hybrid welding, and several approaches using parameter optimization, a laser beam scanning and an arc oscillation have been tried. However the required offset tolerance has not been fully accomplished up to now and laser-arc hybrid welding has not been widely applied in pipeline construction than expected, despite of its high welding speed and deep penetration. In this study, internal welding was adopted to ensure the offset tolerance and sound back bead. The effect of welding parameters on bead shape was investigated at the flat position. Also tolerances for gap and edge misalignment were verified as 0.5 mm and 2.0 mm, respectively. The position welding trials were conducted at several welding positions from the flat to the overhead position in a downward direction. With the fixed welding speed, arc current for gas metal arc welding current and laser output power, adequate welding voltages for gas metal arc welding were suggested for each position.

• Journal of Welding and Joining
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• v.33 no.1
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• pp.41-48
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• 2015

In this study, the effect of heat input on weld metal microstructure and the effects of dissimilar weld heat affected zone in quenched and tempered ASTM A517 on the stainless steel AISI 316L is investigated through the optimization of welding parameters. For this purpose, two welding techniques are used, tungsten-conventional gas and pulsed gas with weld wire ER 309MoL with Diameter 2.4 mm. Research showed that the grain size of the heat affected zone in pulsed welding is less compared with conventional welding; weld metal structure is fully austenitic, it has a finer structure in the pulsed method. Additionally, the growth of weld metal adjacent steel A517 is different from steel 316L. Further, investigation showed that the rate of dilution is less in the pulsed method and the impact energy is increased in each three regions of the weld metal and heat affected zones in the pulsed method; the fracture in the weld metal and heat affected zone of steel 316L is quite soft and it is semi-crispy in the heat affected zone of steel A517.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.14 no.8
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• pp.757-766
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• 2004

This paper focuses on the formulation and validation of an automatic strategy to select the optimal location and direction of strain gauges for the measurement of the modal response. These locations and directions are important to render the strain measurements as robust as possible when a random mispositioning of the gauges and gauge failures are expected. The approach relies on the evaluation of the signal-to-noise ratios of the gauge measurements from strain data of finite element. The multi-step optimization strategy including genetic algorithm is used to find the strain gauge locations-directions that maximize the smallest modal strain signal-to-noise ratio in the absence of gauge failure or its expected value when gauge failure is possible. A flat Plate is used to prove the applicability of the proposed methodology and to demonstrate the effects of the essential parameters of the problem such as the mispositioning level, the probability of gauge failure, and the number of gauges.

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.1400-1403
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• 2004

The current industrial development and the Increase of population along Nakdong River have produced a rapid Increase of wastewater discharge. This has resulted in problem of water quality control and management. Although many efforts have been carried out, water quality has not significantly improved. The goal of this study is to design a NGIS-based water quality management system for the scientific water quality control and management in the Nakdong River. For general water quality analysis, QULA2E model was applied to the Nakdong River. A sensitivity analysis was made to determine significant parameters and an optimization was made to estimate optimal values. The calibration and verification were performed by using observed water quality data for Nakdong River. A water qualify management system for Nakdong River was made by connecting the QUAL2E model to ArcView. It allows a Windows-based Graphic User Interface(GUI) to implement all operation with regard to water quality analysis. The modeling system in this study will be an efficient NGIS for planning of water quality management.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1803-1807
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• 2007

본 연구에서는 개념적인 강우-유출모형인 Tank 모형에 대하여 유역의 다양한 유출특성을 잘 반영할 수 있는 매개변수를 산정하는 데에 그 목적을 두었다. 이를 위한 최적화 알고리즘은 다목적 유전자 알고리즘인 NSGA-II를 선정하여 Tank 모형과 결합하였으며, 4가지의 목적함수를 대상으로 다양한 함수값을 나타내는 비지배관계의 최적군을 생산하였다. 수 백개로 나타나는 최적군의 다양한 해들 중, 특정 목적함수에 대하여서만 정도가 높거나 낮은 편협한 해들을 배제하고 두루 정도가 높은 값을 나타내는 소수의 비지배해들을 추출하기 위하여 선호적 순서화 기법이 적용되었다. 그 결과 많은 해들 중 단 4개의 해가 최우선해의 위치를 갖는 것으로 나타났으며, 이러한 방법론으로 최적화된 해의 적합성을 살펴보고자 국부최적화 기법인 Powell 방법과 기존에 널리 쓰여온 유전자 알고리즘인 SGA(Simple Generic Algoritm)의 결과와 비교 검정을 수행하였다. 비교한 결과 NSGA-II를 적용하여 산정된 매개변수가 4가지 목적함수 및 관측유량과의 통계치에서 두루 양호한 결과를 나타내었다. 또한 관측유량과 함께 도식하여 살펴본 결과, NSGA-II의 최우선해가 타 자동보정 기법에 비하여 상대적으로 관측치에 보다 잘 부합되는 모의유량을 계산하는 것으로 나타났다.

• Structural Engineering and Mechanics
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• v.75 no.5
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• pp.633-642
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• 2020

Artificial neural networks (ANNs) are known as intelligent methods for modeling the behavior of physical phenomena because of it is a soft computing technique and takes data samples rather than entire data sets to arrive at solutions, which saves both time and money. ANN is successfully used in the civil engineering applications which are suitable examining the complicated relations between variables. Functionally graded materials (FGMs) are advanced composites that successfully used in various engineering design. The FGMs are nonhomogeneous materials and made of two different type of materials. In the present study, the bending analysis of functionally graded material (FGM) beams presents on theoretical based on combination of mixed-finite element method, Gâteaux differential and Timoshenko beam theory. The main idea in this study is to build a model using ANN with four parameters that are: Young's modulus ratio (E_t/E_b), a shear correction factor (k_s), power-law exponent (n) and length to thickness ratio (L/h). The output data is the maximum displacement (w). In the experiments: 252 different data are used. The proposed ANN model is evaluated by the correlation of the coefficient (R), MAE and MSE statistical methods. The ANN model is very good and the maximum displacement can be predicted in ANN without attempting any experiments.

• International Journal of Aeronautical and Space Sciences
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• v.6 no.2
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• pp.1-16
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• 2005

Adaptive control methods are studied for the Satellite to isolate vibration in spite of the nonlinear system dynamics and parameter uncertainties of disturbance. First, a centralized control scheme is developed based on the particle swarm optimization(PSO) algorithm and feedback theory to automatically tune controller gains. A simulation study of a 3 degree-of-freedom device was conducted to evaluate the performance of the proposed control scheme. Next, since a centralized control scheme is hard to construct model dynamics and not goad at performance when controller and systems environment are easily changed, a decentralized control scheme is presented to avoid these defects of the centralized control scheme from the point of view of production and maintenance. It is based on the adaptive control methodologies to find PID controller parameters. Experiment studies were conducted to apply the adaptive control scheme and evaluate the performance of the proposed control scheme with those of the conventional control schemes.