• Journal of Nutrition and Health
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• v.34 no.5
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• pp.485-492
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• 2001

The prevalence of type 2 diabetes mellitus has been rapidly increased in parallel with the westernization of eating behavior in Korea. Increased consumption of animal fat and simple sugar can be potential contributors for insulin resistance. The purpose of the study was to determine whether Western-(WD) and Korean-style(KD) diets altered insulin secretion and insulin resistance in male Sprague Dawley rats. Rats weighing 98$\pm$5g were provided by KD(77 En% of starch, 5 En% of corn oil and 13 En% of gluten plus 5 En% of casein), WD(42 En% of starch, 40 En% of butter and 18% of casein) or control diet(62 En% of starch, 20 En% of corn oil and 18% of casein) for 12 weeks. Body weights were lower in KD compared to WD. Fasting blood glucose levels were not different among diets. Insulin secretion from the beta cells was higher by 2.2$\pm$0.4 folds in WD than KD at baseline. In hyperglycemic clamp insulin secretion was higher in WD than KD and CD. Whole body glucose disposal rates referred to the state of insulin sensitivity were lowest in WD among groups. Glycogen deposits in soleus and quadriceps muscles were lowest in WD among all groups, but their triglyceride contents were highest. GLUT4 contents and glycogen synthase were lowest in WD in both muscles. In conclusions, westernization of diets needed more insulin to normalization of blood glucose levels due to increased insulin resistance. Thus, WD would lead to increased prevalence of diabetes mellitus when increased insulin resistance could not be compensated by insulin secretion in the case of elevated blood glucose levels. (Korean J Nutriton 34(5) : 485~492, 2001)

• KSBB Journal
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• v.24 no.5
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• pp.425-431
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• 2009

Hepatocyte growth factor (HGF) and its receptor play an important role in the formation and progression of glioma. In this study, I investigated the ability of HGF to recover of the PSA siRNA-suppressed cell proliferation, migration and invasion in U-251-MG cells. PSA siRNA-transfected U-251-MG cells showed the reduction of the proliferation, migration and invasion with compared to control. Treatment of HGF on the PSA siRNA-transfected U-251-MG cells recovered the ability of proliferation, migration and invasion. These data suggest that PSA and HGF may use unique and parallel signaling cascade leading to the proliferative, migrative and invasive phenotype of U-251-MG cells. I also showed that PSA cooperated with HGF to a migrative and invasive phenotype via the increased secretion of matrix metalloproteinase-2 (MMP-2) and MMP-9.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.3
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• pp.678-684
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• 2013

This paper describes a low-power baseband circuit for SAW-less LTE-Advanced transmitters. The proposed transmitter baseband circuit consists of a 2nd-order Tow-Thomas type active RC-LPF and a 1st-order passive RC LPF. It can provide a 7 multi-channel cut-off frequencies and wide gain control range of -41 dB ~ 0 dB with a 1-dB step. The proposed 2nd-order active RC-LPF adopts an op-amp in which three other sub-op amps are in parallel connected to reduce DC current for different cutoff frequency. In addition, each sub-op amp adopts both Miller and feed-forward phase compensation method to achieve an UGBW of more than 1-GHz with a small DC power consumption. The proposed baseband circuit is implemented in 65-nm CMOS technology, consuming DC power from 6.3 mW to 24.1 mW from a 1.2V supply voltage for each different cut-off frequency.

• Journal of KIISE:Computing Practices and Letters
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• v.6 no.2
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• pp.120-134
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• 2000

In this paper we present a Distributed Object oriented Virtual computing Environment, called DOVE which consists of autonomous distributed objects interacting with one another via method invocations based on a distributed object model. DOVE appears to a user logically as a single virtual computer for a set of heterogeneous hosts connected by a network as if objects in remote site reside in one virtual computer. By supporting efficient parallelism, heterogeneity, group communication, single global name service and fault-tolerance, it provides a transparent and easy-to-use programming environment for parallel applications. Efficient parallelism is supported by diverse remote method invocation, multiple method invocation for object group, multi-threaded architecture and synchronization schemes. Heterogeneity is achieved by automatic data arshalling and unmarshalling, and an easy-to-use and transparent programming environment is provided by stub and skeleton objects generated by DOVE IDL compiler, object life control and naming service of object manager. Autonomy of distributed objects, multi-layered architecture and decentralized approaches in hierarchical naming service and object management make DOVE more extensible and scalable. Also,fault tolerance is provided by fault detection in object using a timeout mechanism, and fault notification using asynchronous exception handling methods

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.2
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• pp.303-310
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• 2018

One of most shocking headlines is a serious chain collision accident (CCA). The development of CCA has a temporal and spatial locality, and the information of the CCA is time-critical. Due to these characteristics of CCA, traffic accident information should be rapidly propagated to drivers in order to reduce chain collisions, right after the first accident occurs. Inter-vehicle communication (IVC) based on ad-hoc communication is one of promising alternatives for locally urgent information propagation. Despite this potential of IVC, research for the effects of IVC on the reduction of CCA has not been reported so far. Therefore, this study develops the parallel platform of microscopic vehicle and IVC communication simulators and then analyses the effects of IVC on the reduction of the second collision related to a series of vehicles. To demonstrate the potential of the IVC-based propagation of urgent traffic accident information for the reduction of CCA, the reduction of approaching-vehicle speed, the propagation speed of accident information, and then the reduction of CCA were analysed, respectively, according to scenarios of combination of market rates and traffic volumes. The analysis results showed that CCA can be effectively reduced to 40~60% and 80~82% at the penetration rates of 10% and 50%, respectively.

• The Journal of Korean Society for Radiation Therapy
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• v.20 no.2
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• pp.115-122
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• 2008

Purpose: The cancer treatment which uses radiation from next year when the X-ray is discovered with the fact that it is started. The radiation treatment technique for a cancer treatment is developed ceaselessly without and it is come and, with advancement of the computer and electromagnetic engineering it joins in and quickly, it was made to do a many development from radiation treatment field. Accordingly, this study is examine in the radiotherapy technique which is developed that importance to therapeutic principles and methods. Materials and Methods: We had investigated record for radiotherapy technique which is developed and we had acquired information widely at clinical experience data. Results: The cancer treatment which uses the radiation of today is repeating a dazzling development. Past the treatment which is two-dimensional it does not correspond in therapeutic objective but currently 3 dimension three-dimensional moulding treatment or centurial control radiation treatment this the fourth dimension therapeutic technique which is in parallel to be introduced the complication solution in compliance with a normal organization protection and the radiation which are a difficult problem of during that time radiation treatment possibly did. Conclusion: 3-dimensional and 4-dimensional modern radiation treatment which is developen is that corresponding in objective of radiation treatment and the evaluation that again it does thick, judges in about the cancer treatment which uses radiation with the fact that the protection of normal organization is almost become accomplished.

• The Journal of Korean Physical Therapy
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• v.12 no.2
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• pp.185-190
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• 2000

Objectives: The purpose of this study was to compare the difference of Lumbar Lordosis Angle(LLA) between patients with Low Back Pain(LBP) and control groups. Methods: Questionnaires were completed by 40 adult LBP patients seeking physical therapy services and by 40 controls at the Department of Physical Therapy. Saejong Neurosurgical Clinic in Taegu city from October 1999 to March 2000. LLA was measured on lateral x-ray films in a standing position. The angle between a line parallel to the top of the first Lumbar(L1) and the top of the fifth Lumbar(L5) was defined LLA. Results: LLA of $29.88^{\circ}$ for LBP patients was a statistically significant decrease from that of $35.31^{\circ}$ for controls in the difference of lumbar lordosis(p<0.01). There were statistically significant differences between senders in patient groups. Females$(32.32^{\circ})$ had significantly greater angles than males$(27.32^{\circ})$(p<0.05), while $36.63^{\curc}$ for female was also greater than $34.12^{\circ}$ for male in the controls. No significant difference was found between age. In patient groups, $27.95^{\circ}$ for below age 40 was a smaller than $32.32^{\circ}$ for above, however, $35.82^{\circ}$ for below age 40 was a little greater than $34.27^{\circ}$ for above in controls. Patients in a sitting posture had greater LLA$(31.35^{\circ}$ than those standing$(28.93^{\circ})$, however values for controls were similar to each other. Conclusion: Results from this study indicate that distinct differences exist among patients and controls and gender, whereas little difference exists in age and working posture.

• Korean Journal of Acupuncture
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• v.34 no.1
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• pp.47-55
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• 2017

Objectives : The purpose of this study is to evaluate the feasibility of further acupuncture research as an effective alternative and safe treatment for abdominal pain control in patients with pancreatitis. Methods and Results : This study is an open-label, assessment-blind, parallel designed pilot clinical trial. Thirty participants will be assigned to the acupuncture group(n=15) and usual care group(n=15). All patients will receive the conventional standard-of-care(SOC) therapy, but only the experimental group will receive acupuncture therapy six times a week, and the duration of acupuncture therapy will be held up to 12 weeks or until the pains are to be resolved. For the conventional SOC therapy, painkiller will be given. In treatment group, the subjects will receive the identical SOC therapy in combination with electroacupuncture therapy on twelve acupuncture points(LI4, PC6, SP6, GB39, ST36, ST37), and auricular acupuncture therapy on five auricular acupuncture points(Sympathetic, Shen Men, Abdomen, Pancreas gall, and Spleen). The primary outcome will be measured using the visual analogue scale(VAS), and the secondary outcome will be measured using the painkiller demand, quality of life index and severity of pancreatitis by abdominal computed tomography(CT). Assessments will be made at baseline and at week 1, 4, 8 and 12. Results of abdominal CT will be evaluated at baseline and at week 12. Conclusions : The result of this trial will provide a basis for the effectiveness and safety of acupuncture treatment for abdominal pain in patients with pancreatitis.

• Journal of Life Science
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• v.17 no.7 s.87
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• pp.905-909
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• 2007

The dual-function protein redox factor-1 (Ref-1) is essential for base excision repair of oxidatively damaged DNA and also governs the activation of many redox-sensitive transcription factors. We examined the role of Ref-1 in regulation of nitric oxide (NO) synthesis employing adenoviral-mediatedoverexpression of Ref-1 in bradykinin-stimulated endothelial cells. Intracellular NO was detected with the NO-sensitive fluorophore DAF-2. Overexpression of Ref-1 potentiates bradykinin-stimulated NO production in endothelial cells. And, cells ifected with AdRef-1 showed higher fluorescence intensity compared with uninfected or AdD1312-infected cells. In parallel with this, over expression of Ref-1 also stimulated endothelial NO synthase (eNOS) enzyme activity, compared with unifected or AdD1312-infected cells, in bradykinin-stimulated cells as well as in unstimulated cells. These results suggest that Ref-1 implicates in endothelium-dependent vasorelaxation resulting from NO production in vascular system.

• Restorative Dentistry and Endodontics
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• v.13 no.2
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• pp.337-348
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• 1988

The purpose of this study was to examine the fracture strength and characteristics of teeth with MOD cavity preparation. Freshly extracted sound maxillary premolars were cleaned and stored in normal saline solution $37^{\circ}C$ for 72 hours before experiments. The roots of teeth were embedded in a self-curing resin, and the exposed crown were maintained in a vertical position by a modelling wax in a brass ring. The MOD cavities were prepared with No. 57 carbide bur under high speed to a depth of 2.0mm and a width of 2.0mm(Fig.1). All the prepared teeth specimens were divided into 7 groups according to the mode of cavity form and restorative materials (Table 1, 2): Group I, unpreapred, intact teeth as control Group II, prepared cavity without restoration Group III, prepared teeth restored with amalgam Group IV, prepared teeth restored with composite resin (P-10) Group V, prepared teeth with beveled enamel margins restored with composite resin (P-10) Group VI, prepared teeth restored with light-cured composite resin (P-30) Group VII, prepard teeth with beveled enamel margins restored with light-cured composite resin (P-30) After placement of restorations, all of the specimens were stored in water at $37^{\circ}C$ for 72 hours before testing. All of the specimens were tested on the Instron Universal Testing machine (No. 6025) in order to evaluate the strength of fracture. One metal ball 5.0mm in diameter contacting the specimens parallel to the occlusal surface was used to in this study (Fig. 1). The fracture characteristics of the specimens were examined with naked eye and in the scanning electron microscope (JSM-20). The results obtained from this study were as follows: 1. The mean fracture strength was the highest in group VI and that in group II was the lowest. 2. The progress of crack of teeth propagated into the pulp cavity. 3. In case of the group of the restored teeth, the crack occurred to be accompanied with cuspal fracture. 4. The crack of restored teeth was initiated along the pulpo-axial line angle of the cavity.