• Title/Summary/Keyword: ParA

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Comparison of Measured and Calculated Carboxylation Rate, Electron Transfer Rate and Photosynthesis Rate Response to Different Light Intensity and Leaf Temperature in Semi-closed Greenhouse with Carbon Dioxide Fertilization for Tomato Cultivation (반밀폐형 온실 내에서 탄산가스 시비에 따른 광강도와 엽온에 반응한 토마토 잎의 최대 카복실화율, 전자전달율 및 광합성율 실측값과 모델링 방정식에 의한 예측값의 비교)

  • Choi, Eun-Young;Jeong, Young-Ae;An, Seung-Hyun;Jang, Dong-Cheol;Kim, Dae-Hyun;Lee, Dong-Soo;Kwon, Jin-Kyung;Woo, Young-Hoe
    • Journal of Bio-Environment Control
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    • v.30 no.4
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    • pp.401-409
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    • 2021
  • This study aimed to estimate the photosynthetic capacity of tomato plants grown in a semi-closed greenhouse using temperature response models of plant photosynthesis by calculating the ribulose 1,5-bisphosphate carboxylase/oxygenase maximum carboxylation rate (Vcmax), maximum electron transport rate (Jmax), thermal breakdown (high-temperature inhibition), and leaf respiration to predict the optimal conditions of the CO2-controlled greenhouse, for maximizing the photosynthetic rate. Gas exchange measurements for the A-Ci curve response to CO2 level with different light intensities {PAR (Photosynthetically Active Radiation) 200µmol·m-2·s-1 to 1500µmol·m-2·s-1} and leaf temperatures (20℃ to 35℃) were conducted with a portable infrared gas analyzer system. Arrhenius function, net CO2 assimilation (An), thermal breakdown, and daylight leaf respiration (Rd) were also calculated using the modeling equation. Estimated Jmax, An, Arrhenius function value, and thermal breakdown decreased in response to increased leaf temperature (> 30℃), and the optimum leaf temperature for the estimated Jmax was 30℃. The CO2 saturation point of the fifth leaf from the apical region was reached at 600ppm for 200 and 400µmol·m-2·s-1 of PAR, at 800ppm for 600 and 800µmol·m-2·s-1 of PAR, at 1000ppm for 1000µmol of PAR, and at 1500ppm for 1200 and 1500µmol·m-2·s-1 of PAR levels. The results suggest that the optimal conditions of CO2 concentration can be determined, using the photosynthetic model equation, to improve the photosynthetic rates of fruit vegetables grown in greenhouses.

PHDCM : Efficient Compression of Hangul Text in Parallel (PHDCM : 병렬 컴퓨터에서 한글 텍스트의 효율적인 축약)

  • Min, Yong-Sㅑk
    • The Journal of the Acoustical Society of Korea
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    • v.14 no.2E
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    • pp.50-56
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    • 1995
  • This paper describes an efficient coding method for Korean characters using a three-state transition graph. To our knowledge, this is the first achievement of its kind. This new method, called the Paralle Hangul Dynamic Coding Method(PHDCM), compresses about 3.5 bits per a Korean character, which is more than 1 bit shorter than the conventional codes introduced thus far to achieve extensive code compression. When we ran the method on a MasPar machine, which is on SIMD SM (EFEW-PRAM)., it achieved a 49.314-fold speedup with 64 processors having 10 million Korean characters.

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Saponins from the Callus Mass of Phytolacca americana

  • Chi, Hyung-Joon;Kim, Hyun-Soo
    • Archives of Pharmacal Research
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    • v.8 no.1
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    • pp.15-20
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    • 1985
  • Strong anti-inflammatory saponins Phytolacca americana (Phytolaccaceae) wereobtained from callus mass derived from the stems and also from that derived from the roots of cultivated Phytolacca americana (which were designated as PAS and PAR, respectively). The callus were grown on Linsmair and Skoog's agar medium supplemented with 1ppm OF 2, 4-dichlorophenoxyacetic acid. Phytol accoside B and D were obtained from PAS and phytolaccoside A and B from PAR. The thin layer chromatograms of the crude saponins from PAS and PAR were similar to those of original plants. PAS contained phytolaccoside B as a major component while phytolaccoside E was a major saponin in original plants.

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Flow analysis of 3-Dimensional Power-Augmented Ram Wing in Ground Effect (3차원 PAR WIG (Powder Augmented Ram Wing in Ground Effect) 의 수치연구)

  • 곽승현
    • Journal of Ocean Engineering and Technology
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    • v.11 no.1
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    • pp.55-64
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    • 1997
  • A wing operating in close proximity to the ground exhibits a reduction in induced drag, which increase the lift/drag ratio. The poert-augmented ram (RAR) phenomenon involves directiing the efflux from forward mounted propulsion ststem under the wings, with the efflux nearly stagnated under the wings. In the present paper, 3 dimentional PAR was numerically studied by solving the Navier-Stokes equations. Pressure distribution and velocity vectors are calculated around the wing surface and the ground. Through the numerical simulation, Cp values and lift/drag ratio are carefully reviewed by changing the height/chord; 0.05, 0.1, 0.3 and 0.8. The shape of model is NACA 0012 with a span/chord ratio of 3.0. According to the numerical results, the relationship between lift/drag and height/chord is fairly reasonable.

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A Novel CFR Algorithm using Histogram-based Code Domain Compensation Process for WCDMA Basestation (히스토그램 기반 코드 영역 보상 기법을 적용한 W-CDMA 기지국용 CFR 알고리즘)

  • Chang, Hyung-Min;Lee, Won-Cheol
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.12C
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    • pp.1175-1187
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    • 2007
  • This paper proposes a novel crest factor reduction (CFR) algorithm to be deployed on WCDMA basestation. Generally speaking, it is well described that the reduction of peak-to-average ratio (PAR) yields the possibility of using low cost power amplifier such that the basesation becomes economic However, the simple reduction of PAR could degrade the signal quality measured by either peak code domain error (PCDE) or error vector measurement (EVM), and the level of channel interference constrained by adjacent channel leakage ratio (ACLR). Regarding these imperfections, this paper introduces an effective CFR algorithm in which the function of filter-dependent CFR (FDCFR) incorporated with the histogram-based waterfilling code domain compensation (HBWCDC) carries out. To verify the performance of the proposed CFR technique, substantial simulations including comparative works are conducted with obeying W-CDMA basestation verification specification. To exploit the superiority, the performance of the proposed method is tentatively compared with that associated to the simple memoryless clipping method and the memory-required filter-dependent clipping method.

Tristetraprolin Inhibits the Growth of Human Glioma Cells through Downregulation of Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor mRNAs

  • Ryu, Jinhyun;Yoon, Nal Ae;Lee, Yeon Kyung;Jeong, Joo Yeon;Kang, Seokmin;Seong, Hyemin;Choi, Jungil;Park, Nammi;Kim, Nayoung;Cho, Wha Ja;Paek, Sun Ha;Cho, Gyeong Jae;Choi, Wan Sung;Park, Jae-Yong;Park, Jeong Woo;Kang, Sang Soo
    • Molecules and Cells
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    • v.38 no.2
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    • pp.156-162
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    • 2015
  • Urokinase plasminogen activator (uPA) and urokinase plasminogen activator receptor (uPAR) play a major role in the infiltrative growth of glioblastoma. Downregulatoion of the uPA and uPAR has been reported to inhibit the growth glioblastoma. Here, we demonstrate that tristetraprolin (TTP) inhibits the growth of U87MG human glioma cells through downregulation of uPA and uPAR. Our results show that expression level of TTP is inversely correlated with those of uPA and uPAR in human glioma cells and tissues. TTP binds to the AU-rich elements within the 3' untranslated regions of uPA and uPAR and overexpression of TTP decreased the expression of uPA and uPAR through enhancing the degradation of their mRNAs. In addition, overexpression of TTP inhibited the growth and invasion of U87MG cells. Our findings implicate that TTP can be used as a promising therapeutic target to treat human glioma.

Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid

  • Joo, Yeon Ah;Chung, Hyunjin;Yoon, Sohyun;Park, Jong Il;Lee, Ji Eun;Myung, Cheol Hwan;Hwang, Jae Sung
    • Biomolecules & Therapeutics
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    • v.24 no.5
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    • pp.529-535
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    • 2016
  • Atopic dermatitis (AD) results from gene and environment interactions that lead to a range of immunological abnormalities and breakdown of the skin barrier. Protease-activated receptor 2 (PAR2) belongs to a family of G-protein coupled receptors and is expressed in suprabasal layers of the epidermis. PAR2 is activated by both trypsin and a specific agonist peptide, SLIGKV-$NH_2$ and is involved in both epidermal permeability barrier homeostasis and epithelial inflammation. In this study, we investigated the effect of lobaric acid on inflammation, keratinocyte differentiation, and recovery of the skin barrier in hairless mice. Lobaric acid blocked trypsin-induced and SLIGKV-$NH_2$-induced PAR2 activation resulting in decreased mobilization of intracellular $Ca^{2+}$ in HaCaT keratinocytes. Lobaric acid reduced expression of interleukin-8 induced by SLIGKV-$NH_2$ and thymus and activation regulated chemokine (TARC) induced by tumor necrosis factor-a (TNF-${\alpha}$) and IFN-${\gamma}$ in HaCaT keratinocytes. Lobaric acid also blocked SLIGKV-$NH_2$-induced activation of ERK, which is a downstream signal of PAR2 in normal human keratinocytes (NHEKs). Treatment with SLIGKV-$NH_2$ downregulated expression of involucrin, a differentiation marker protein in HaCaT keratinocytes, and upregulated expression of involucrin, transglutamase1 and filaggrin in NHEKs. However, lobaric acid antagonized the effect of SLIGKV-$NH_2$ in HaCaT keratinocytes and NHEKs. Topical application of lobaric acid accelerated barrier recovery kinetics in a SKH-1 hairless mouse model. These results suggested that lobaric acid is a PAR2 antagonist and could be a possible therapeutic agent for atopic dermatitis.

Analysis of Sequence Type and Fluoroquinolone Resistance in Ciprofloxacin-Resistant Escherichia coli (Ciprofloxacin 내성 대장균에서 Sequence Type과 Fluoroquinolone 내성의 분석)

  • Cho, Hye Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.3
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    • pp.217-224
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    • 2021
  • Fluoroquinolone (FQ) resistant gram-negative pathogens have emerged worldwide, and the recent increase in FQ resistant Escherichia coli is of great concern in Korea. This study investigated FQ resistance determinants and the epidemiological relationship of 56 ciprofloxacin-resistant E. coli isolated from a tertiary hospital in Daejeon, South Korea from June to December 2018. Molecular epidemiology was investigated by multilocus sequence typing (MLST). Polymerase chain reaction (PCR) and sequence analysis were performed to identify chromosomal mutations in the quinolone resistance determining regions (QRDR) of gyrA, gyrB, parC, and parE and to describe the occurrence of the following plasmid-mediated quinolone resistance (PMQR) genes: aac(6)-Ib-cr, qepA, qnrA, qnrB, qnrC, qnrD, and qnrS. MLST analysis showed 12 sequence types (STs) and the most prevalent ST was ST131 (31/56, 55.4%), followed by ST1193 (13/56, 23.2%), and ST405 (3/56, 5.4%). In 56 ciprofloxacin-resistant E. coli isolates, Ser83→Leu and Asp87→Asn in gyrA and Ser80→Ile and Glu84→Val in parC (51.8%, 29/56) were the most frequent amino acid substitutions and aac(6)-Ib-cr (33.9%, 19/56) was the most common PMQR gene. These results of FQ resistance determinants were more frequently observed in ST131 compared with other clones. Continuous monitoring of the epidemiological characteristics of ciprofloxacin-resistant E. coli isolates and further investigation of FQ resistance determinants are necessary.

Variations of BVOCs Emission Characteristics according to Increasing PAR (유효광합성량 (PAR)의 증가에 따른 BVOCs 배출 특성 변화)

  • Son, Youn-Suk;Hwang, Yoon-Seo;Sung, Joo-Han;Kim, Jo-Chun
    • Journal of Korean Society for Atmospheric Environment
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    • v.28 no.1
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    • pp.77-85
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    • 2012
  • In this study, emission rates (ER) of biogenic volatile organic compounds (BVOCs) were measured by varying levels of photosynthetically active radiation (PAR). An appropriate plan for ozone reduction according to increasing ecology area ratio in future metropolitan areas was suggested. Several trees were selected as representative tree species in urban areas. Emission rates and composition ratios of monoterpene and isoprene emitted from these trees were estimated and compared. As a result, it was found that emission rates of BVOCs were considerably different depending on tree species. Especially, BVOCs emitted from Platanus orientalis and Quercus mongolica could significantly affect ozone increase in the metropolitan area, because the emission rates were several thousands to ten thousand times higher than those emitted from Zelkova serrata and Prunus serrulata. Furthermore, it was observed that emission rates of BVOCs by species increased maximum up to 10 times when PAR, which has close relations with temperature, rose. It was concluded that tree species such as Zelkova serrata et al., was appropriate for metropolitan areas since the species has low ozone potential and good landscape. Suppose this type of trees are planted on purpose in the urban areas, better ambient air quality will be promised in the future.

Protease-Activated Receptor 2 Is Involved in Th2 Responses against Trichinella spiralis Infection

  • Park, Mi-Kyung;Cho, Min-Kyoung;Kang, Shin-Ae;Park, Hye-Kyung;Kim, Yun-Seong;Kim, Ki-Uk;Ahn, Soon-Cheol;Kim, Dong-Hee;Yu, Hak-Sun
    • Parasites, Hosts and Diseases
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    • v.49 no.3
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    • pp.235-243
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    • 2011
  • In order to get a better understanding of the role of protease-activated receptor 2 (PAR2) in type 2 helper T (Th2) cell responses against Trichinella spiralis infection, we analyzed Th2 responses in T. spiralis-infected PAR2 knockout (KO) mice. The levels of the Th2 cell-secreted cytokines, IL-4, IL-5, and IL-13 were markedly reduced in the PAR2 KO mice as compared to the wild type mice following infection with T. spiralis. The serum levels of parasite-specific IgE increased significantly in the wild type mice as the result of T. spiralis infection, but this level was not significantly increased in PAR2 KO mice. The expression level of thymic stromal lymphopoietin, IL-25, and eotaxin gene (the genes were recently known as Th2 response initiators) of mouse intestinal epithelial cells were increased as the result of treatment with T. spiralis excretory-secretory proteins. However, the expression of these chemokine genes was inhibited by protease inhibitor treatments. In conclusion, PAR2 might involve in Th2 responses against T. spiralis infection.