• 제목/요약/키워드: Panax ginseng meyer

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Development of a single-nucleotide-polymorphism marker for specific authentication of Korean ginseng (Panax ginseng Meyer) new cultivar "G-1"

  • Yang, Dong-Uk;Kim, Min-Kyeoung;Mohanan, Padmanaban;Mathiyalagan, Ramya;Seo, Kwang-Hoon;Kwon, Woo-Saeng;Yang, Deok-Chun
    • Journal of Ginseng Research
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    • 제41권1호
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    • pp.31-35
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    • 2017
  • Background: Korean ginseng (Panax ginseng) is a well-known medicinal plant of Oriental medicine that is still in practice today. Until now, a total of 11 Korean ginseng cultivars with unique features to Korean ginseng have been developed based on the pure-line-selection method. Among them, a new cultivar namely G-1 with different agricultural traits related to yield and content of ginsenosides, was developed in 2012. Methods: The aim of this study was to distinguish the new ginseng cultivar G-1 by identifying the unique single-nucleotide polymorphism (SNP) at its 45S ribosomal DNA and Panax quinquefolius region than other Korean ginseng cultivars using multiplex amplification-refractory mutation system-polymerase chain reaction (ARMS-PCR). Results: A SNP at position of 45S ribosomal DNA region between G-1, P. quinquefolius, and the other Korean ginseng cultivars was identified. By designing modified allele-specific primers based on this site, we could specifically identified G-1 and P. quinquefolius via multiplex PCR. The unique primer for the SNP yielded an amplicon of size 449 bp in G-1 cultivar and P. quinquefolius. This study presents an effective method for the genetic identification of the G-1 cultivar and P. quinquefolius. Conclusion: The results from our study shows that this SNP-based approach to identify the G-1 cultivar will be a good way to distinguish accurately the G-1 cultivar and P. quinquefolius from other Korean ginseng cultivars using a SNP at 45S ribosomal DNA region.

흰쥐의 항산화 활성에 미치는 홍삼, 삼백초, 복분자 추출물의 상승효과 (Synergistic Effects of extracts from Korean Red ginseng, Saururus chinensis(Lour.) Baill. and Rubus coreanus Miq. on Antioxidative Activities in Rats)

  • 최면;신건재;최근표;도재호;김종대
    • 한국약용작물학회지
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    • 제11권2호
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    • pp.148-154
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    • 2003
  • 홍삼(panax ginseng C.A. Meyer) 추출물 단독의 항산화 활성과 홍삼추출물에 삼백초(Saururus chinensis(Lour.) Baill.)와 복분자(Rubus coreanus Miq.) 추출물을 농도별로 보충 급여 하였을 때 나타나는 상승효과를 알아보기 위하여 Sprague Dawley rat에 이들 추출물을 8주간 섭취시킨 후 희생시켜 간장 cytosol중의 superoxide dismutase, catalase, glutathione peroxidase, GST 등의 항상화 효소계 활성을 측정하였다. 그 결과, 홍삼급여군의 superoxide dismutase, catalase, glutathione peroxidase의 효소활성이 대조군에 비해 농도 의존적으로 높았다. 특히 홍삼 단독보다는 삼백초와 복분자를 보충급여시 상승효과가 높았으며 급여기간이 길수록 그 효과가 높았다.

혈청지질의 광산화 반응에 미치는 인삼추출물의 영향 (The Effect of Ginseng Extracts on Photooxidation in Serum Lipid)

  • 백태홍;천현자
    • Journal of Ginseng Research
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    • 제13권2호
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    • pp.234-238
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    • 1989
  • In the presence of a photosensitizer, rose bengal, phooxidatlon in serum total lipids has been studied and the effects of ginseng water extract and saponins on it have reviewed. In the presence of rose bengal, serum total lipids undergo photooxidation and produce lipid hydroperoxides. On the other hand, ginseng water extract and dial saponins largely inhibit photooxidation and decrease the amount of lipid hydroperoxides in serum total lipids.

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EXPERIMENTAL AND EPIDEMIOLOGICAL EVIDENCE FOR NON-ORGAN SPECIFIC CANCER PREVENTIVE EFFECT OF KOREAN GINSENG AND IDENTIFICATION OF ACTIVE COMPOUNDS

  • Yun, Taik-Koo
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.17-18
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    • 2001
  • Panax ginseng C. A. Meyer has been the most highly recognized medicinal herb in the Orient. The prolonged administration of red ginseng extract significantly inhibited the incidence of hepatoma and also proliferation of pulmonary tumors induced by aflatoxin B$_1$and urethane. Statistically significant anticarcinogenic effects were observed in powders and extract of 6 year-dried fresh ginseng, 5 and 6 year-white ginseng and 4, 5 and 6 year-red ginseng by 9 week medium-term anticarcinogenicity test using benzo[a]pyrene (Yun's model).(omitted)

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