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Synergistic Effects of extracts from Korean Red ginseng, Saururus chinensis(Lour.) Baill. and Rubus coreanus Miq. on Antioxidative Activities in Rats  

Choe, Myeon (Department of Animal Products Science, Korea Nutrition Institute, Kangwon National University)
Shin, Geon-Jae (School of Biotechnology and Bioengineering, Korean Nutrition Institute, Kangwon National University)
Choi, Geun-Pyo (Dept. of Food & Life Science, Gangwon Provincial University)
Do, Jae-Ho (Korea Ginseng Crop.)
Kim, Jong-Dai (School of Biotechnology and Bioengineering, Korean Nutrition Institute, Kangwon National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.2, 2003 , pp. 148-154 More about this Journal
Abstract
This study was designed to investigate the effect of Korean Red ginseng(Panax ginseng C.A. Meyer) extracts on antioxidative activities in Sprague-Dawley rats. This study also evaluated the synergistic effect of Korean red ginseng(RG) extracts with Saururus chinensis(Lour.) Baill(SC). and Rubus coreanus Miq.(RC) extracts. Experimental groups were divided into supplementation type(RG extracts, RG with SC and RC extracts) and amounts of extracts. Rats were received drinking water with or without RG, RC and SC extracts for eight weeks. In the antioxidant enzyme activities of liver cytosol, superoxide dismutase, catalase and glutathione peroxidase activities were significantly increased in RG groups and RG with SC and RC groups compared to control group. The antioxidative activities were increased in proportion to supplementation period and amounts of extracts. These results suggest that RG, RC and SC extracts have an beneficial effect to enhance the cellular antioxidant activities in rats.
Keywords
Panax ginseng C.A.; Saururus chinensis(Lour.) Baill.; Rubus coreanus Miq.; antioxidant enzyme;
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