• 제목/요약/키워드: PU.1

검색결과 687건 처리시간 0.027초

추나의학 용어 표준화 필요성 연구 (A Study for the Necessity of Terminology Standardization in Chuna Medicine)

  • 권정주;김민우;박경무;장건;조현철;남항우;신병철;임형호;송윤경
    • 척추신경추나의학회지
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    • 제7권1호
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    • pp.1-13
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    • 2012
  • Objectives: Although chuna medicine has progressed distinguishingly, yet chuna medical terminology hasn't been standardized. So there are a lot of difficulties in translating chuna related book and their meaning cannot be conveyed properly. For this reason, we could say standardization of chuna medical terminology is very essential. Purpose of our study was to develope a standard database of concept terms for chuna medicine, in addition, we considered establishing fundamental principles of chuna medical terminology. Methods: To select standard chuna medical terms, we sorted important chuna medical index words. Then we sorted those words into a group that has same meanings and united to one single term. In the meantime, we extracted index words from 26 domestic and foreign manual technique related books and sorted them out and based on these word, we translated chuna medical terms to Korean terms. In the case of chuna technique terms, we searched chuna text books for term those were wrongly used, and corrected them by suggesting fundamental principles of terminology. Results: 664 chuna words were selected as standard chuna terms and have been translated to English terms. In the process, adscititious words such as anatomical terms and title of books were exempted and selected only important words that could be used as index of chuna terms. In deciding essential elements of chuna technique terms, patient position, contact point, segmental contact point, malposition, procedure method were selected. Conclusions: Correcting chuna medical terms in a sort period could cause confusion, but in long term perspective, in the aspect of conveying the meaning clearly and education purpose, standardizing of chuna medical terminology must be done. From this study, standardization of chuna medical terms were chosen in large category, but further studies must be followed in order to standardize terms of subdivisional categories.

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Polymeric Material Application for The Production of Ceramic Foam Catalyst

  • Sangsuriyan, Anucha;Yeetsorn, Rungsima;Tungkamani, Sabaithip;Sornchamni, Thana
    • International Journal of Advanced Culture Technology
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    • 제3권1호
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    • pp.21-30
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    • 2015
  • Ceramic foams are prepared as positive images corresponding to a plastic foam structure which exhibits high porosities (85-90%). This structure makes the ceramic foams attractive as a catalyst in a dry reforming process, because it could reduce a high pressure drop problem. This problem causes low mass and heat transfers in the process. Furthermore, the reactants would shortly contact to catalyst surface, thus low conversion could occur. Therefore, this research addressed the preparation of dry reforming catalysts using a sol-gel catalyst preparation via a polymeric sponge method. The specific objectives of this work are to investigate the effects of polymer foam structure (such as porosity, pore sizes, and cell characteristics) on a catalyst performance and to observe the influences of catalyst preparation parameters to yield a replica of the original structure of polymeric foam. To accomplish these objectives industrial waste foams, polyurethane (PU) and polyvinyl alcohol (PVA) foams, were used as a polymeric template. Results indicated that the porosity of the polyurethane and polyvinyl alcohol foams were about 99% and 97%. Their average cell sizes were approximate 200 and 50 micrometres, respectively. The cell characteristics of polymer foams exhibited the character of a high permeability material that can be able to dip with ceramic slurry, which was synthesized with various viscosities, during a catalyst preparation step. Next, morphology of ceramic foams was explored using scanning electron microscopy (SEM), and catalyst properties, such as; temperature profile of catalyst reduction, metal dispersion, and surface area, were also characterized by $H_2-TPR$ and $H_2-TPD$ techniques, and BET, respectively. From the results, it was found that metal-particle dispersion was relatively high about 5.89%, whereas the surface area of ceramic foam catalysts was $64.52m^2/g$. Finally, the catalytic behaviour toward hydrogen production through the dry reforming of methane using a fixed-bed reactor was evaluated under certain operating conditions. The approaches from this research provide a direction for further improvement of marketable environmental friendly catalyst production.

효소분해법에 의한 키조개부산물 젓갈의 제조 (Processing of Fermented Squeezed-type Pen Shell By-product by Proteolytic Enzyme)

  • 강훈이;강태중;배태진;김현주
    • 한국수산과학회지
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    • 제27권5호
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    • pp.509-514
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    • 1994
  • 키조개 부산물을 이용하여 속성 젓갈화를 시도하였다. 마쇄한 키조개부산물에 Protin P $5\%$를 가하여 pH 7.0, $55^{\circ}C$에서 1시간 동안 가수분해시킨 후 불활성화를 위하여 $100^{\circ}C$에서 40분간 열처리시키되, 풍미를 개선하기 위하여 $10\%$의 invert sugar를 첨가하였다. 또한 제품의 물성개선을 위하여 PGDG을 $8\%$ 가하여 유화시킨 후 $2\%$의 한천과 $6\%$의 전분을 함께 첨가하여 조직감을 갖는 반고형 상태로 하고 최종적으로 식염농도를 $15\%$로 조절하였다. 시료로 사용한 키조개부산물은 패주를 제외한 나머지 부분으로 전내용고형물 중량의 $51.6\%$를 차지하였다. 풍미개선을 위하여 $10\%$의 invert sugar를 첨가하여 열처리한 것이 비린내와 쓴맛을 억제시켰다. 또한 한천 $2\%$ 및 전분 $6\%$의 첨가는 대조구에 비하여 hardness, springiness 및 chewiness를 개선시키는 효과를 보였다. 그리고 $23{\pm}3^{\circ}C$에서 저장하였을 때 생균수는 60일째까지 검출되지 않았다. 키조개부산물로 제조한 젓갈중의 주요 아미노산들로는 Glu, Arg, Asp, Leu, Lys, Gly 및 Ala 순으로, 전체 유리아미노산 함량의 $60\%$ 이상을 차지하였고, 저장 90일후에도 양적순서와 함량이 크게 변하지 않았다.

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신소재를 사용한 인체조직모사물질의 합성과 초음파 물리적 특성에 관한 연구 (The Study on Ultrasound Physical Characteristic and Synthesis of Tissue Mimicking Materials Used New Materials)

  • 마상철;김화선;안영만
    • 대한방사선기술학회지:방사선기술과학
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    • 제33권3호
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    • pp.245-252
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    • 2010
  • 본 연구는 주제인 폴리우레탄(polyurethane, PU)과 새로운 형태의 n-type 산란재를 사용하여 합성한 조직모사물질(tissue mimicking materials : TMM)에 대해 국제표준규격 IEC 60601-2-37(2007)의 Annex D.D가 권고한 인체 연조직(soft tissue)의 음향학적 특성 기준에 준해, 전파속도, 임피던스, 감쇠계수 특성 등을 분석하였으며, 영상특성은 SONOACE 9900C PRIME(MEDESON Co.), 3.5 MHz 컨벡스 프로브(2.5-5.0 MHz)로 초음파 휘도와 최대투과심도를 분석 평가하여 다음과 같은 결론을 얻었다. 주제인 prepolymer와 polyol mixture를 혼합하고 n-type 산란재를 0~8%로 점차 증가하여 합성하였을 때, 1. 조직모사물질의 전파속도는 산란재가 증가할수록 연조직에 더 가깝게 수렴(convergence)하였다. 2. 음향임피던스는 산란재가 감소할수록 연조직에 더 가깝게 수렴하였다. 3. 감쇠계수는 산란재가 증가할수록 증가하였다. 4. 영상 평균휘도는 산란재가 증가할수록 증가하였으나 역치가 있었다. 5. 최대투과심도는 산란재 6% 조직모사물질에서 연조직에 가깝게 수렴하였다.

3차원 기공구조를 이용한 정전기반 에너지 하베스팅 나노발전기 소자제조 (3D Porous Foam-based Triboelectric Nanogenerators for Energy Harvesting)

  • 전상헌;정정화;홍석원
    • 마이크로전자및패키징학회지
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    • 제26권1호
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    • pp.9-15
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    • 2019
  • 본 연구에서는 3차원 기공구조를 지닌 금속 및 고분자 소재를 이용한 수직 마찰모드의 정전기반 나노발전기(triboelectric nanogenerator, TENG) 제조기술을 소개하고 이에 관한 응용 연구를 수행하였다. 다양한 장점을 지닌 3차원 기공구조를 활용하여 설계된 간단하며 효율적인 나노발전기로, 반복적인 접촉/분리를 통해, 120 V에 이르는 순간 전압특성과 최대 출력 $0.74mW/m^2$을 획득하였다. 실제적인 응용 연구로 48개의 발광소자 구동 실험을 실시하였으며, 저전력 소비 전자소자 장치로의 응용 확장성을 확인하기 위해 회로 구성을 통한 커패시터 축적기능을 확인하였다. 본 연구에서 소개하는 정전기반 에너지 하베스팅 기술은 매우 경제적으로 제조할 수 있는 실용적인 접근방식으로, 반복적으로 가해지는 마찰에 의한 정전력을 효율적으로 획득하여 가까운 미래에 자가발전(self-powered)형 소형 전기소자 구동, 휴대형 전자기기 및 대규모의 전자 발전 장치에 적용 가능할 것으로 기대된다.

Preparation and characterization of Mn doped copper nitride films with high photocurrent response

  • Yu, Aiai;Hu, Ruiyuan;Liu, Wei;Zhang, Rui;Zhang, Jian;Pu, Yong;Chu, Liang;Yang, Jianping;Li, Xing'ao
    • Current Applied Physics
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    • 제18권11호
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    • pp.1306-1312
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    • 2018
  • The Mn-doped copper nitride ($Cu_3N$) films with Mn concentration of 2.0 at. % have high crystallinity and uniform surface morphology. We found that the as-synthesized Mn-doped $Cu_3N$ films show suitable optical absorption in the visible region and the band gap is ~1.48 eV. A simple photodetector based on Mn doped $Cu_3N$ films was firstly fabricated via magnetron sputtering method. The fabricated device with doping of Mn demonstrated high photocurrent response and fast response shorter than 0.1 s both for rise and decay time superior to the pure $Cu_3N$. Furthermore, the energy levels of Mn-doped Cu3N matched well with ITO and Ag electrode. The excellent photoelectric properties reflect a good balance between sensitivities and response rate. Our investigation reveals the excellent potential of Mn-doped $Cu_3N$ films for application of photodetectors.

2.7Gbps/1.62Gbps DisplayPort 송신기용 PLL 및 확산대역 클록 발생기의 설계 (A Design of PLL and Spread Spectrum Clock Generator for 2.7Gbps/1.62Gbps DisplayPort Transmitter)

  • 김영신;김성근;부영건;허정;이강윤
    • 대한전자공학회논문지SD
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    • 제47권2호
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    • pp.21-31
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    • 2010
  • 본 논문에서는 DisplayPort용 전자기기 또는 클록 발생을 요구하는 다양한 회로에서 발생 할 수 있는 전자방해(EMI) 현상을 줄일 수 있는 위상 동기 루프와 확산 대역 클록 발생기를 구현 하였다. 이 시스템은 기본적으로 송신용 위상 동기 루프와 확산 대역 클록 발생기 구현을 위한 전하펌프2 와 기준주파수 분주기 등으로 구성된다. 본 논문에서는 2.7Gbps/1.62Gbps DisplayPort 응용 회로에 적합 하도록 10개의 다중 위상 신호를 출력 할 수 있는 270MHz/162MHz 듀얼 모드 위상 동기 루프를 설계 하였고 추가적으로 1.35GHz/810MHz의 위상 동기 루프를 설계하여 지터를 크게 감소시킬 수 있는 구조를 제안하였다. 270MHz/162MHz 위상 동기 루프와 5:1 시리얼라이저 2개, 그리고 1.35GHz 위상 동기 루프와 2:1 시리얼라이저를 연동함으로써 지터 성분을 크게 줄일 수 있다. 위상 동기 루프에서 사용 된 주파수 전환 다중위상 전압제어 발진기와 더불어 DisplayPort 규격에 맞는 주파수 전환이 가능 하도록 분주기를 공유하고 50% duty ratio를 보장할 수 있는 주파수 분주기 구조를 제안 하였다. 또한, 지터를 줄이기 위해서 출력전류 오차를 크게 줄일 수 있는 전하펌프 구조를 제안 하였다. 0.13 um CMOS 공정을 사용하여 설계 하였으며, 270MHz/162MHz PLL의 칩 면적은 $650um\;{\times}\;500um$ 이고, 1.35GHz/810MHz PLL의 칩 면적은 $600um\;{\times}\;500um$ 이다. 270MHz/162MHz 위상 동기 루프 전압제어 발진기의 조절 범위는 330MHz이고, 위상 잡음은 1MHz 오프셋에서 -114cBc/Hz, 확산대역 클록 발생기의 확산 진폭도 는 0.5%이고, 변조 주파수는 31kHz이다. 전체 전력 소모는 48mW이다.

사망진단서(사체검안서) 상의 선행사인으로부터 사망통계의 원사인이 선정되는 비율: (3개 대학병원에서 교부된 사망진단서를 중심으로) (The rate that underlying causes of death for vital statistics are derived from the underlying causes of death recorded at death certificates: (a study on the death certificates issued from three university hospitals))

  • 박우성;박석건;정철원;김우철;탁우택;김부연;서순원;김광환;서진숙;부유경
    • 한국의료질향상학회지
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    • 제11권1호
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    • pp.4-14
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    • 2004
  • Background : To examine the problems involved in writing practice of death certificates, we compared the determination of underlying cause of death for vital statistics using recorded underlying cause of death in issued death statistics. Methods : We collected 688 mortality certificates issue in year of 2,000 from 3 university hospitals. And we also collected vital statistics from ministry of statistics. The causes of death were coded by experienced medical record specialists. And causes of death determined at ministry of statistics for national vital statistics were mapped to causes of death recorded at each death certificates. The rate that underlying causes of death for vital statistics were derived from underlying causes of death recorded at issued death certificates were analysed. Results : 64.5% of underlying cause of death for could be derived from underlying cause of death recorded at issued death certificates, 8.6% derived from intermediate cause of death, and 3.9% derived from direct cause of death. In 23% of cases, underlying cause of death could not be derived using issued death certificates. The rate that underlying cause of death for vital statistics could be derived from underlying cause of death recorded at death certificates was different between 3 university hospitals. And the rate was also different between death certificates and postmortem certificates. We classified the causes of death using 21 major categories. The rate was different between diseases or conditions that caused death too. Conclusion : When we examined the correctness of death certificate writing practice using above methods, correctness of writing could not be told as satisfactory. There was difference in correctness of writing between hospitals, between death certificates and postmortem certificates, and between diseases and conditions that caused death. With this results, we suggested some strategy to improve the correctness of death certificate writing practice.

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miRNA-183 Suppresses Apoptosis and Promotes Proliferation in Esophageal Cancer by Targeting PDCD4

  • Yang, Miao;Liu, Ran;Li, Xiajun;Liao, Juan;Pu, Yuepu;Pan, Enchun;Yin, Lihong;Wang, Yi
    • Molecules and Cells
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    • 제37권12호
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    • pp.873-880
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    • 2014
  • In our previous study, miRNA-183, a miRNA in the miR-96-182-183 cluster, was significantly over-expressed in esophageal squamous cell carcinoma (ESCC). In the present study, we explored the oncogenic roles of miR-183 in ESCC by gain and loss of function analysis in an esophageal cancer cell line (EC9706). Genome-wide mRNA micro-array was applied to determine the genes that were regulated directly or indirectly by miR-183. 3'UTR luciferase reporter assay, RT-PCR, and Western blot were conducted to verify the target gene of miR-183. Cell culture results showed that miR-183 inhibited apoptosis (p < 0.05), enhanced cell proliferation (p < 0.05), and accelerated G1/S transition (p < 0.05). Moreover, the inhibitory effect of miR-183 on apoptosis was rescued when miR-183 was suppressed via miR-183 inhibitor (p < 0.05). Western blot analysis showed that the expression of programmed cell death 4 (PDCD4), which was predicted as the target gene of miR-183 by microarray profiling and bioinformatics predictions, decreased when miR-183 was over-expressed. The 3'UTR luciferase reporter assay confirmed that miR-183 directly regulated PDCD4 by binding to sequences in the 3'UTR of PDCD4. Pearson correlation analysis further confirmed the significant negative correlation between miR-183 and PDCD4 in both cell lines and in ESCC patients. Our data suggest that miR-183 might play an oncogenic role in ESCC by regulating PDCD4 expression.

Chinese Patients with Gastric Cancer Need Targeted Adjuvant Chemotherapy Schemes

  • Shi, Wen-Tao;Wei, Lei;Xiang, Jin;Su, Ke;Ding, Qiong;Tang, Meng-Jie;Li, Ji-Qiang;Guo, Yi;Wang, Pu;Zhang, Jing-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.5263-5272
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    • 2012
  • Background: Gastric cancer (GC) is one of the most common cancers in China. Adjuvant chemotherapy (AC) is a routine auxiliary treatment for GC recommended by the guidelines issued in 2011 by the Ministry of Health of the People's Republic of China, but the relevant credible consequences in China have been insufficient because of China's late start and ethical concerns. Methods: A series of databases, including Cochrane Library, MEDLINE, EMBASE, the Chinese database of the National Knowledge Infrastructure and the VIP database, were searched by 2 reviewers independently for studies investigating AC for GC through March 2012. The retrieved literature was screened according to the eligibility criteria. Results: A total of 35 randomized control trials (RCTs) were subjected to the final analysis, including 4,043 patients in treatment group and 3,884 in the control group, as well as 4 clinical-control trials (CCTs), which accessed the final analysis with 238 and 252 patients, respectively. AC reduced the risk of death as a protective treatment with statistical significance (HR=0.91, 95%CI: [0.85, 0.97], P=0.002), and it seemed more effective for Asian than non-Asian patients. The effects of AC were not influenced by the starting time (P>0.05). D2 lymphadenectomy-based chemotherapy was effective (HR=0.89, 95%CI: [0.80, 0.99], P=0.04). Oral S-1 40 mg/m2 after D2 lymphadenectomy might be a better choice for Asians with advanced GC and might result in a greater reduction of adverse events than in non-Asian patients. GRADE quality assessment determined that the strength of the evidence from foreign studies from Europe, the United States and Asian countries other than China was high, while it was moderate for Chinese studies. Conclusion: AC was effective or even curative in Chinese patients in general, although it is still necessary to optimize a targeted AC scheme for Chinese patients with GC.