• 한국산업정보학회논문지
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• 제14권4호
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• pp.1-7
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• 2009

이 논문은 다목적 공정순서계획 알고리즘을 소개한다. 공정순서계획이란 가용한 기계들을 이용하여 원재료를 가공 완료된 부품으로 변형해주는 최적 공정순서들을 결정하는 일이다. 어느 컴퓨터 지원 공정계획 시스템에서나, 가공작업 순서의 결정은 부품 가공이나 부품 도면상의 기술적인 요구사항들을 충족시켜주기 위한 가장 중요한 활동 중의 하나이다. 여기서, 목표는 생산시간, 생산비용, 기계가동률 또는 이들을 복합적으로 만족시켜주는 최적 가공순서를 생성하는 일일 것이다. 파레토 스트라튬 니치 큐비클 (PS NC) 유전 알고리즘이 두 가지 상호 배타적인 기준인 생산비용과 생산품질을 동시에 최적화 시켜주는 가공순서들을 찾는데 이용되었다. 예제에 의한 검증은 제안된 PS NC 유전자 알고리즘이 공정계획문제에 있어서 효과적이며 효율적인 결과를 가져오는 것을 보여준다.

• The Plant Pathology Journal
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• 제22권4호
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• pp.339-347
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• 2006

Riboflavin caused induction of systemic resistance in chickpea against Fusarium wilt and charcoal rot diseases. The dose effect of 0.01 to 20 mM riboflavin showed that 1.0 mM concentration was sufficient for maximum induction of resistance; higher concentration did not increase the effect. At this concentration, riboflavin neither caused cell death of the host plant nor directly affected the pathogen's growth. In time course observation, it was observed that riboflavin treated chickpea plants were inducing resistance 2 days after treatment and reached its maximum level from 5 to 7 days and then decreased. Riboflavin had no effect on salicylic acid(SA) levels in chickpea, however, riboflavin induced plants found accumulation of phenols and a greater activities of phenylalanine ammonia lyase(PAL) and pathogenesis related(PR) protein, peroxidase was observed in induced plant than the control. Riboflavin pre-treated plants challenged with the pathogens exhibited maximum activity of the peroxidases 4 days after treatment. Molecular weight of the purified peroxidase was 42 kDa. From these studies we demonstrated that riboflavin induced resistance is PR-protein mediated but is independent of salicylic acid.

• Mycobiology
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• 제29권1호
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• pp.48-53
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• 2001

Plants have the ability to acquire an enhanced level of resistance to pathogen attack after being exposed to specific biotic stimuli. To obtain plant growth-promoting rhizobacteria inducing resistance against cucumber anthracnose by Colletotrichum orbiculare, more than 800 strains of rhizobacteria were screened in the greenhouse. Among these strains, Bacillus amyloliquefaciens solate EXTN-1 showed significant disease control efficacy on the plants. Induction of pathogenesis-related(PR-la) gene expression by EXTN-1 was assessed using tobacco plants transformed with PR-1a::$\beta$-glucuronidase(GUS) construct. GUS activities of tobacco treated with EXTN-1 and salicylic acid-treated transgenic tobacco were significantly higher than those of tobacco plants with other treatments. Gene expression analyses indicated that EXTN-1 induces the accumulation of defense-related genes of tobacco. The results showed that some defense genes are expressed by the treatment with EXTN-1 suggesting the similar resistance mechanism by salicylic acid.

• 대한한의학회지
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• 제31권4호
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• pp.115-128
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• 2010

Objectives: The aim of this study was to investigate deodorizing effectsof medicinal herbs (Mume Fructus, Eriobotryae Folium, Acanthopanacis Cortex, Angelicae Dahuricae Radix) for development of a gargle solution. Methods: 1. The antimicrobial effects of medicinal herbs were evaluated with the minimal bactericidal concentration (MBC) and the change of the number of viable cells in the herb extracts(1%) for 48 hrs against P. gingivalis 2561 and Pr. intermedia ATCC 25611. 2. Deodorizing activity of each herb and Garglin $Mint^{(R)}$gainst methyl mercaptan were analyzed by gas chromatography (GC). 3. We used the malodor modeling of the salivary sediment system with a Halimeter. 4. In the preliminary clinical study, the baseline concentration of VSC in the oral cavity of each subject was measured by Halimeter. Subjects would gargle for 30 seconds with cysteine. After 4 minutes subjects would gargle for 30 seconds with Garglin and herb extracts (2%). Subsequently, concentration of VSC were measured at 0, 4, 8, 12 and 20 minutes. Results: 1. MBC of Mume Fructusfor P. gingivalis 2561 was determined to be <1% and MBCs of Eriobotryae Folium for P. gingivalis 2561 and Pr. intermedia ATCC 25611 were determined to be <2% and <1%, respectively. Mume Fructus (1%) completely suppressed the P. gingivalis cell viability from 5 hrs and Eriobotryae Folium (1%) completely suppressed the Pr. intermedia cell viability from 48 hrs. 2. In GC analysis, deodorizing activities were 91.54% with Mume Fructus, 87.97% with Eriobotryae Folium, 100% with Acanthopanacis Cortex, 72.36% with Angelicae Dahuricae Radix and 40.54% with Garglin $Mint^{(R)}$. 3. In malodor modeling of the salivary sediment system, each of the medicinal herbs had significantly inhibitory effect on malodor formation (p<0.05). 4. In the preliminary clinical study, the concentration of VSC of the herb groups was significantly lower than of the control group, but not in Garglin $Mint^{(R)}$. Conclusions: Mume Fructus, Eriobotryae Folium, Acanthopanacis Cortex and Angelicae Dahuricae Radixhave deodorizing activities and potential as an effective mouthwash against oral malodor.

• 한국응용과학기술학회지
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• 제34권3호
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• pp.443-450
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• 2017

Dawley 계 숫컷 흰쥐(200~210g)를 정상군, $CCl_4$-대조군, $CCl_4$-실험군으로 나누어 실험군은 갈근 에탄올 추출물을 1,000mg/kg,b.w의 용량으로 1일1회7일간 경구 투여 후 사염화탄소를 0.6mg/kg,b.w의 용량으로 복강내 주사 후 다음날 개복하여 혈청내의 Alanine aminotransferase(ALT), Aspartate aminotransferase(AST), Alkaline phosphatase(ALP), Glutamyltranspeptidase(${\gamma}$-GT), Lactate dehydro-genase(LDH)의 활성도와 중성지방, 콜레스테롤 함량을 측정한 결과 갈근 추출물 투여군에서 $CCl_4$-대조군과 비교하여 유의적인 감소(p<0.05)를 나타내었으며, HDL-콜레스테롤은 유의적인 증가(P0.05)를 나타내었다. 간조직중의 지질과산화 함량과 Catalase(CAT), Glutathione peroxiddase(GSH-Px)의 항산화 효소 활성은 유의적인 감소를 나타내었다. 반면에 간 조직중의 glutathione 함량은 유의적인 증가를 나타내었다. 이 실험 결과 갈근 에탄올 추출물은 사염화탄소 투여에 의한 간 손상을 억제하는 보호물질과 항산화 물질을 함유하고 있음을 알 수 있었다.

• 지역사회간호학회지
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• 제6권2호
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• pp.259-274
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• 1995

The study is to grasp the problems related to operation of Maternity clinic of public health centers in seoul and needs for public health of community in relation to consumers and providers in order to improve efficiency of community public health for mothers and children. Four pregnancy woman, who receive medical care at the maternity clinic of M public health centers in seoul and understand the purpose of this study, and one nurse who works at the were the objects of this field study. Participating observation and intensive interviews were conducted to collect data. All of them were performed as necessary from time to time since December, 1994, and not during a specific period. Through an data analysis in the order of sector analysis and classification analysis, the data were classified into specific patterns and the results are the following; 1. All of the subjects were using both private hospitals and public clinics, but managing activities prior to delivery were not carried out in accordence with theories for those activities. 2. The subjects showed two types of response to utilizing maternity clinic. they answered that the advantages of the clinic were 'short waiting time for medical treatment', 'medical treatment by female doctors' and 'economical benefit.' Meanwhile, they gave negative response to the problems of 'non-implementation of delivery' 'uncleanness and insufficient facilities', 'limited time of treatment', 'lack of expertise' and 'want of public health education for materity.' 3. Problems related to operation of maternity clinic were 'lack of experts', 'irrational facility structure' and 'absolutely lack budget'. In terms of the status of managing the subjects, 'programs only aimed at attaining the central-government-assigned objects' and 'limited management before and after delivery by non-implementing delivery' were pointed out to be problems. Regarding public health education before delivery and PR relations, 'superficial public health education for maternity' and 'absence of PR programs' were named. In planning and evaluation, 'absence of autonomous planning and evaluation by the clinic itself' was a major problem in operating the clinic. 4. 'Substantial health education and PR', 'supplementation of facilities and eqipment', 'development' and supply of demanded service by the subjects', 'implementation of autonomous programs', and 'reinforcement of supplementary education' were presented as alternatives for efficient opration of maternity clinics.

• The Journal of Korean Physical Therapy
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• 제31권2호
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• pp.134-139
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• 2019

Purpose: This study examined the most effective exercise while performing shoulder abduction below ninety degrees. Methods: Thirty two healthy individuals (17 males, 15 females) participated and performed four exercises, 1) Posterior fly, 2) Prone row, 3) Modified prone cobra, and 4) External rotation in the prone position. Surface electromyography (sEMG) was used to measure the electrical activities for the lower, middle and upper fiber of trapezius and serratus anterior. Results: A significant difference in the muscle activities of the upper/middle/lower trapezius and serratus anterior was observed among the three different positions in terms of the PF (posterior fly), PR (prone row), and MPC (modified prone cobra) (p<0.05). In post-hoc analysis, the activities of the lower and upper trapezius were significantly higher than those of the upper trapezius and serratus anterior (p<0.05). In addition, in ERP (external rotation in prone), there was a significant difference in each activity of the muscles. Post-hoc results indicated that the upper trapezius showed greater EMG activity than the other three muscles. Conclusion: External rotation in the prone position revealed the highest activation of the lower trapezius compared to upper trapezius muscle activity. This may be particularly useful in isolating the lower trapezius in cases where excessive scapular elevation is noted. Therefore, the most effective lower trapezius exercise should be performed below ninety degrees of shoulder abduction.

• 국제학술발표논문집
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• The 8th International Conference on Construction Engineering and Project Management
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• pp.249-256
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• 2020

Historical construction health and safety (H&S) challenges, in terms of a range of resources and issues, continue to be experienced, namely design process-related hazards are encountered on site, workers are unaware of the hazards and risks related to the construction process and its activities, activities are commenced on site without adequate hazard identification and risk assessments (HIRAs), difficulty is experienced in terms of real time monitoring of construction-related activities, workers handle heavy materials, plant, and equipment, and ultimately the experience of injuries. Given the abovementioned, and the advent of Industry 4.0, a quantitative study, which entailed the completion of a self-administered questionnaire online, was conducted among registered professional (Pr) and candidate Construction H&S Agents, to determine the potential of Industry 4.0 to contribute to resolving the challenges cited. The findings indicate that Industry 4.0 technologies such as augmented reality (AR), drone technology, virtual reality (VR), VR based H&S training, and wearable technology /sensors have the potential to resolve the cited H&S challenges as experienced in construction. Conclusions include that Industry 4.0 technologies can finally address the persistent H&S challenges experienced in construction. Recommendations include: employer associations, professional associations, and statutory councils should raise the level of awareness relative to the potential implementation of Industry 4.0 relative to H&S in construction; case studies should be documented and shared; tertiary construction management education programmes should integrate Industry 4.0 into all possible modules, especially H&S-related modules, and continuing professional development (CPD) H&S should address Industry 4.0.

• 한국콘텐츠학회논문지
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• 제11권9호
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• pp.275-292
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• 2011

본 연구에서 Promotion Mix 활동이 브랜드 자산에 어떠한 영향을 미치며, 이는 궁극적으로 구매의도와 어떠한 관계가 있는가를 고찰하고자 수도권지역에 거주하고 있으며, 자동차를 구매한 경험이 있는 20대 이상의 성인남녀를 연구대상으로 설문조사를 하였다. 수집된 자료의 통계처리는 SPSS 12.0 for Windows 통계 패키지와 AMOS 7.0 프로그램을 활용하여 분석하였다. 분석결과, 첫째, 기업의 Promotion Mix활동과 브랜드 자산의 관계를 분석한 결과, 기업의 광고활동에 대한 평가가 긍정적일수록 브랜드 인지도, 애호도, 이미지가 증가하였다. 또한, 기업의 PR 활동에 대한 평가가 긍정적일수록 브랜드 인지도, 이미지, 애호도가 증가한 것으로 나타났다. 둘째, 영업사원의 Promotion 활동과 브랜드자산의 관계를 분석한 결과, 영업사원의 사회적 역량은 브랜드 인지도와 애호도를 향상시켰으며 전략적 역량은 브랜드 인지도, 애호도, 이미지를 향상시키는 것으로 나타났다. 셋째, 브랜드 자산과 구매의도의 관계를 분석한 결과를 보면, 브랜드 인지도는 만족도와 재구매(구전)의도에 유의한 정(+)의 영향을 미치고, 브랜드 애호도는 만족도와 재구매(구전)의도에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 또한, 브랜드 이미지는 만족도와 재구매(구전)의도에 유의한 정(+)의 영향을 미치는 것으로 나타나 브랜드 자산과 구매의도의 관계가 밀접한 상관관계가 있다는 것을 알 수 있었다.

• 문화기술의 융합
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• 제5권3호
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• pp.311-316
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• 2019

붓순나무의 잎과 가지를 50 % 아세톤 수용액으로 추출하고, 추출된 각각의 조추출물(crude)을 n-hexane, chloroform, EtOAc와 물($H_2O$)로 분획한 후, 각각의 분획물에 대하여 항산화 활성과 항바이러스 활성 시험을 실시하였다. 항산화 활성은 붓순나무 잎의 경우 EtOAc용성 분획물에서 가지의 경우 EtOAc용성 분획물과 수용성 분획물에서 가장 좋은 활성을 보였고, 대조군으로 사용된 BHT 및 ${\alpha}$-tocopherol에 비하여 우수한 항산화 활성이 있는 것으로 나타났다. 항바이러스 활성의 경우, HRV 1B와 EV 71에서는 항바이러스 활성이 미흡한 것으로 나타났으나, Influenza PR8에서는 어느 정도 항바이러스 활성을 갖고 있는 것으로 나타났다. 특히 EtOAc용성 분획물과 수용성 분획물에서 80% 이상의 세포 생존률이 나타난 것으로 보아 붓순나무의 극성 분획물에는 항바이러스 효과를 가지고 있는 활성 물질이 존재하고 있다는 사실을 알 수 있었다. 이상의 결과를 통하여 우리는 붓순나무로 부터 얻어진 추출물이 항산화제 및 항바이러스제의 원료로 사용 될 수 있는 천연 바이오매스 자원으로써의 가능성이 있음을 제시하였다.