• 제목/요약/키워드: PER1

검색결과 20,909건 처리시간 0.048초

노인병원의 재원환자 1인당 일평균 원가 및 적정이윤 계산 (Calculation of the Costs and Optimal profits per Inpatient-day of the Geriatric Hospitals)

  • 황인경;김재선;최황규
    • 한국병원경영학회지
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    • 제8권4호
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    • pp.149-181
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    • 2003
  • It has been asserted that per diem payment system should be introduced, in place of the current fee-for-service system, for payment of the inpatient services of the geriatric hospitals, Based on the assentation, this study aims at calculating costs and profits per inpatient-day of the geriatric hospitals, and thereby at contributing to the managerial improvement from the both sides of the Government and the hospitals. Relevant data of the three months, May to August, 2002 were collected from the five geriatric hospitals, and per inpatient-day costs and profits were calculated for the three disease groups. Major results and conclusions are as follow : Firstly, total costs per insured inpatient-day of the geriatric hospitals are 65, 389 won for dementia (including optimal profit of 3,858 won), 69,730 won for stroke (including optimal profit of 4,117 won), and 70,085 won for other diseases (including optimal profit of 4,134 won). Secondly, the amount of the non-insured costs per inpatient-day occupies 34.5% of the total costs for dementia, 30.3% for stroke, and 30.1% for other diseases. Thirdly, the total amount of the per inpatient-day costs calculated including the optimal profits is, on the average, higher by 12% than the present price level calculated for the current fee-far-service system. This implies that the present price level should rise by 12% when the current fee-far-service payment system be maintained, and Finally, introduction of a sliding-scale payment system should be considered for the inpatient medical management fees for the length of stay over six months or more that are being cut in the claim examination process by the insurance corporation.

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UPPER BOUNDS FOR SUBPERMANENTS OF NONNEGATIVE MATRICES

  • Cheon, Gi-Sang
    • 대한수학회논문집
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    • 제10권1호
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    • pp.27-34
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    • 1995
  • For an $n \times n$ matrix $A = [a_{ij}]$, the permanent of A, per A, is defined by $$ per(A) = \sum_{\sigma}{a_{1 \simga(1)} \cdots a_{n \sigma(n)}}, $$ where $\sigma$ runs over all permutations of ${1,\cdots,n}.

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Differentially Expressed Genes in Period 2-Overexpressing Mice Striatum May Underlie Their Lower Sensitivity to Methamphetamine Addiction-Like Behavior

  • Sayson, Leandro Val;Kim, Mikyung;Jeon, Se Jin;Custodio, Raly James Perez;Lee, Hyun Jun;Ortiz, Darlene Mae;Cheong, Jae Hoon;Kim, Hee Jin
    • Biomolecules & Therapeutics
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    • 제30권3호
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    • pp.238-245
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    • 2022
  • Previous reports have demonstrated that genetic mechanisms greatly mediate responses to drugs of abuse, including methamphetamine (METH). The circadian gene Period 2 (Per2) has been previously associated with differential responses towards METH in mice. While the behavioral consequences of eliminating Per2 have been illustrated previously, Per2 overexpression has not yet been comprehensively described; although, Per2-overexpressing (Per2 OE) mice previously showed reduced sensitivity towards METH-induced addiction-like behaviors. To further elucidate this distinct behavior of Per2 OE mice to METH, we identified possible candidate biomarkers by determining striatal differentially expressed genes (DEGs) in both drug-naïve and METH-treated Per2 OE mice relative to wild-type (WT), through RNA sequencing. Of the several DEGs in drug naïve Per2 OE mice, we identified six genes that were altered after repeated METH treatment in WT mice, but not in Per2 OE mice. These results, validated by quantitative real-time polymerase chain reaction, could suggest that the identified DEGs might underlie the previously reported weaker METH-induced responses of Per2 OE mice compared to WT. Gene network analysis also revealed that Asic3, Hba-a1, and Rnf17 are possibly associated with Per2 through physical interactions and predicted correlations, and might potentially participate in addiction. Inhibiting the functional protein of Asic3 prior to METH administration resulted in the partial reduction of METH-induced conditioned place preference in WT mice, supporting a possible involvement of Asic3 in METH-induced reward. Although encouraging further investigations, our findings suggest that these DEGs, including Asic3, may play significant roles in the lower sensitivity of Per2 OE mice to METH.

쌀단백질의 L-lysin.HCI 강화에 관한 연구 (Effeet of L-lysin.HCI Fortification on the Quality of Rice Protein)

  • 이숙희
    • 한국식품영양과학회지
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    • 제8권1호
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    • pp.21-24
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    • 1979
  • 쌀단백질(蛋白質)의 아미노 강화효과와 과잉강화에 의한 쌀단백질(蛋白質)의 아미노산(酸) 불균형 현상(現像)을 살펴보기 위하여 시판(市販) 백미(白米)에 $0.25{\sim}1.0%$ 수준으로 L-lysin HCI를 강화하여 동물(動物) 사육실험(飼育實驗)을 행(行)한 결과(結果) 다음과 같은 결과(結果)를 얻었다. 1. 강화력이 0.25%일 때 체중증가량(增加量) 및 PER이 가장 높았다. 2. $0.5%{\sim}1.0%$ 수준에선 첨가하지 않은 대조군보다 PER이 높았으나 0.25% 보다는 낮았다. 3. 강화수준 1.0%까지는 아미노산(酸) 불균형으로 인한 강화 역효과는 나타나지 않았다.

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Relationship between Representative Anthropometric Dimensions and Income Levels for Korean

  • Kee, Do-Hyung
    • 대한인간공학회지
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    • 제31권1호
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    • pp.255-259
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    • 2012
  • Objective: This study aims to investigate relationship between representative anthropometric dimensions and income levels for Korean from 1958 to 1989. The anthropometric dimensions include stature and body weight, and GNP per head was used as an index of income level. Background: Although anthropometric dimensions were affected by varying factors such as genetic, environmental and socioeconomic factors, most studies on anthropometry have focused on measurement methods, providing data and their characteristics. Method: Anthropometric data were retrieved from homepages of Korean Agency for Technology and Standards, and Ministry of Culture, Sports & Tourism, and GNPs per head by year from Korean Statistical Information Service. Results: During analysis period, statures and body weights for males and females increased by 6.4cm and 6.1cm, 10.7kg and 4.0kg, respectively. Infants' stature and body weight nearly linearly increased with GNPs per head. Anthropometric dimensions of stature and body weight were very positively correlated with GNPs per head. Conclusion: This study revealed that income levels significantly affect stature and body weight. Application: The results would be used as a valuable basic data when establishing government policies related to anthropometry.

간장발효에 관여하는 효모에 관한 연구(제 1보) -제국중에 생육하는 효모에 대하여- (Studies on the Yeasts for the Brewing of Soy sauce ( I ) -Isolation, identification and classification of the Yeasts in the soy sauce koji-)

  • 이택수;이석건
    • Applied Biological Chemistry
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    • 제13권1호
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    • pp.97-103
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    • 1970
  • 간장국제조과정중에 생육하는 효모들을 계수 및 분리 동정하고 TTC 정색에 의하여 유발한 결과는 다음과 같다. 1. 간장국 1g 중의 효모수는 3일국에 $97{\times}10^3$, 4일국에 $135{\times}10^3$, 5일국에 $179{\times}10^3$개로서 제국일수의 경과에 따라 효모수가 증가하였다. 2. 이들 효모의 TTC 정색에 었어서 White가 53.6${\sim}$71.9%, Red가 5.6${\sim}$11.1%, Red pink가 6.8${\sim}$1905 pink가 11.1${\sim}$22.6%로서 white 효모가 가장 많았고 Red 효모가 가장 적었다. 3. 30주를 임의 분리하여 동정한 결과 Saccharomyces rouxii 5주, Saccharomyces fermentati 2주, Saccharomyces rosei 1주, Hansenula suaveolens 1주, Hansenula anomala 6주, Pichia polymorpha 6주, Debaryomyces nicotianae 2주, Debaryomyces hansenii 2주, Torulopsis candida 2주, Torulopsis sake 2주, Candida pelliculosa 1주등 6속 11종으로 동정되었다. 4. 등정한 이들 효모를 TTC 정색에 따라 유별한 결과 Hansenula suaveolens, Hansenula anomala, Candida pelliculosa, Debaryomyces nicotianae, Pichia polymorpha 등은 국중에 생육하는 전체 효모의 약 60%를 차지하는 TTC white 효모구에 속하였으며 Saccharomyces rouxii와Saccharomyces rosei는 Red 로 Saccharomyces fermentati와 Debaryomyces hansenii는 Red pink로 Torulopsis candida와 Torulopsis sake는 pink로 나타났다. 5. 분리된 효모의 대부분이 무염 또는 식염10% 합유배지에서 잘 생육하나 15-18% 식염 합유배지에서는 생육이 거이 억제되었다.

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인산질비료 및 인산질강화퇴비가 수도의 수량 및 수량 구성요소에 미치는 영향 (The effect of superphosphate fertilizer and composts enriched with superphosphate on the grain yield and yield components of rice)

  • 김정기
    • 한국작물학회지
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    • 제7권1호
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    • pp.65-70
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    • 1969
  • 이 시험은 비옥도가 중위로 보이는 유기공함량 5.0%, 전질소함량 2.8%, 인산 166ppm, 가리 1.13me/100g 및 규산함량 3.9ppm이 되는 논에서 고수준의 인산시용의 효과와 아울러 완숙 ?퇴비에 중과인산석회의 혼적에 의한 인산질강화퇴비의 시용이 수도의 생육과 수량구성요소 및 수량에 미치는 영향을 알고저 실시하였는데 그 결과는 다음과 같다. 1. 인산의 효과는 10a당 5kg, 7.5kg 및 10kg의 시용구간에 수량과 그밖에 수량 구성각요소들은 유의차가 없으며 인산증시의 효과가 없었다. 2. 완숙한 볏짚퇴비 1000kg/10a 시용과 인산 5kg, 7.5kg 및 10kg/0a 시용구간에 현미수량은 통계적으로 유의차가 없었으나 수치적으로는 퇴비 1000kg/10a 시용구 220kg 인산 5kg/10a시용구 232kg, 7.5kg/10a 시용구 266kg 및 10kg/.0a시용구 243kg을 냈다. 3. 인산비료 즉 중과인산석회와 비료를 수도에 시용하는 경우에는 시용전에 그들을 미리 혼적하여 두었다가 시용한 것이 수량구성각요소가 증수의 방향으로 발현되며 현미량이 증대하였다. 4. 인산과 퇴비시용에 있어서의 교호작용은 각수량구성요소에 따라 구구하였는데 수량에 있어서는 인산과 비료를 병용하는 것이 유리함을 인정하였다. 5. 이 시험의 10개처리구중에서 현미수량이 가장많았던 것은 10a당 인산 7.5kg과 퇴비 1,000kg을 3개월간 혼적해두었다가 시용한 구와 인산 5kg과 퇴비 1.000kg을 마찬가지로 3개월간 혼적해 두었다가 시용한 구가 가장 많았다. 6. 이 시험에서 퇴비의 시용은 등열율을 높이는데 효과가 컸다.

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일 대학병원 호스피스 병동 입원 환자의 간호활동시간 측정과 원가산정 (Determination of Cost and Measurement of nursing Care Hours for Hospice Patients Hospitalized in one University Hospital)

  • 김경운
    • 간호행정학회지
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    • 제6권3호
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    • pp.389-404
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    • 2000
  • This study was designed to determine the cost and measurement of nursing care hours for hospice patients hostpitalized in one university hospital. 314 inpatients in the hospice unit 11 nursing manpower were enrolled. Study was taken place in C University Hospital from 8th to 28th, Nov, 1999. Researcher and investigator did pilot study for selecting compatible hospice patient classification indicators. After modifying patient classification indicators and nursing care details for general ward, approved of content validity by specialist. Using hospice patient classification indicators and per 5 min continuing observation method, researcher and investigator recorded direct nursing care hours, indirect nursing care hours, and personnel time on hospice nursing care hours, and personnel time on hospice nursing care activities sheet. All of the patients were classified into Class I(mildly ill), Class II (moderately ill), Class III (acutely ill), and Class IV (critically ill) by patient classification system (PCS) which had been carefully developed to be suitable for the Korean hospice ward. And then the elements of the nursing care cost was investigated. Based on the data from an accounting section (Riccolo, 1988), nursing care hours per patient per day in each class and nursing care cost per patient per hour were multiplied. And then the mean of the nursing care cost per patient per day in each class was calculated. Using SAS, The number of patients in class and nursing activities in duty for nursing care hours were calculated the percent, the mean, the standard deviation respectively. According to the ANOVA and the $Scheff{\'{e}$ test, direct nursing care hours per patient per day for the each class were analyzed. The results of this study were summarized as follows : 1. Distribution of patient class : class IN(33.5%) was the largest class the rest were class II(26.1%) class III(22.6%), class I(17.8%). Nursing care requirements of the inpatients in hospice ward were greater than that of the inpatients in general ward. 2. Direct nursing care activities : Measurement ${\cdot}$ observation 41.7%, medication 16.6%, exercise ${\cdot}$ safety 12.5%, education ${\cdot}$ communication 7.2% etc. The mean hours of direct nursing care per patient per day per duty were needed ; 69.3 min for day duty, 64.7 min for evening duty, 88.2 min for night duty, 38.7 min for shift duty. The mean hours of direct nursing care of night duty was longer than that of the other duty. Direct nursing care hours per patient per day in each class were needed ; 3.1 hrs for class I, 3.9 hrs for class II, 4.7 hrs for class III, and 5.2 hrs for class IV. The mean hours of direct nursing care per patient per day without the PCS was 4.1 hours. The mean hours of direct nursing care per patient per day in class was increased significantly according to increasing nursing care requirements of the inpatients(F=49.04, p=.0001). The each class was significantly different(p<0.05). The mean hours of direct nursing care of several direct nursing care activities in each class were increased according to increasing nursing care requirements of the inpatients(p<0.05) ; class III and class IV for medication and education ${\cdot}$ communication, class I, class III and class IV for measurement ${\cdot}$ observation, class I, class II and class IV for elimination ${\cdot}$ irrigation, all of class for exercise ${\cdot}$ safety. 3. Indirect nursing care activities and personnel time : Recognization 24.2%, house keeping activity 22.7%, charting 17.2%, personnel time 11.8% etc. The mean hours of indirect nursing care and personnel time per nursing manpower was 4.7 hrs. The mean hours of indirect nursing care and personnel time per duty were 294.8 min for day duty, 212.3 min for evening duty, 387.9 min for night duty, 143.3 min for shift duty. The mean of indirect nursing care hours and personnel time of night duty was longer than that of the other duty. 4. The mean hours of indirect nursing care and personnel time per patient per day was 2.5 hrs. 5. The mean hours of nursing care per patient per day in each class were class I 5.6 hrs, class II 6.4 hrs, class III 7.2 hrs, class IV 7.7 hrs. 6. The elements of the nursing care cost were composed of 2,212 won for direct nursing care cost, 267 won for direct material cost and 307 won for indirect cost. Sum of the elements of the nursing care cost was 2,786 won. 7. The mean cost of the nursing care per patient per day in each class were 15,601.6 won for class I, 17,830.4 won for class II, 20,259.2 won for class III, 21,452.2 won for class IV. As above, using modified hospice patient classification indicators and nursing care activity details, many critical ill patients were hospitalized in the hospice unit and it reflected that the more nursing care requirements of the patients, the more direct nursing care hours. Emotional ${\cdot}$ spiritual care, pain ${\cdot}$ symptom control, terminal care, education ${\cdot}$ communication, narcotics management and delivery, attending funeral ceremony, the major nursing care activities, were also the independent hospice service. But it is not compensated by the present medical insurance system. Exercise ${\cdot}$ safety, elimination ${\cdot}$ irrigation needed more nursing care hours as equal to that of intensive care units. The present nursing management fee in the medical insurance system compensated only a part of nursing car service in hospice unit, which rewarded lower cost that that of nursing care.

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벼담수 직파 재배에서 파종 입수가 생육 및 수량에 미치는 영향 (Effect of Number of Sowing Grain on the Rice Growth and Yield in Direct Sowing Culture on Irrigated Paddy Field)

  • 이종철;문창식;서해영;최범열
    • 한국작물학회지
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    • 제14권
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    • pp.41-45
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    • 1973
  • 본 시험은 중부지방에서 담수직파재배에 알맞은 파종립수를 구명함과 파종립수에 EK른 수량 및 수량구성요소의 변이를 알고져 1972년에 수행하였던 바 그 결과를 요약하면 다음과 같다. 1. 최고분얼수는 밀파할수록 직선적으로 증가하여 280립 파종구에서 최고수치를 보였고 그 이후는 점차 감소되었으며 분얼에 대한 경합은 $m_2$당 280립이상 파종구에서 뚜렸했다. 2. 유효경비율은 $m_2$당 120립부터 280립 파종구까지는 파종밀도가 증가될수록 감소되다가 그 이후는 점차 증가되었다. 3. 최고분얼수가 $m_2$당 1,000개 이하에서는 얼자간 경합이 적었다. 4. 수수와 파종립수는 현저한정(+)의 상관이 인정되었고 수수와 일수영화수, 수수와 동숙비율은 (-)의 상관 경향이었다. 5. 수량과 $m_2$당 영화수는 r=0.929이며 수량과 수수는 r=0.695, 수수와 $m_2$당 영화수는 r=0.796이었다. 또한 수량과 수량구성요소간의 순위상관을 보면 수량과 수수가 가장 상관이 높았으며 (r=0.954_ 담수직파에서 수량을 지배하는 요인은 수수이었다. 6. 수량은 $m_2$당 280립 파종구에서 최고를 나타냈다.

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여대생의 식습관에 따른 식사 다양성 평가 (Evaluation of Dietary Variety by Food Habits in Female University Students)

  • 이보경;이종현
    • 한국식품영양학회지
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    • 제24권4호
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    • pp.687-701
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    • 2011
  • The purpose of this study was to assess dietary variety by food habits(regularity of meal time, regularity of repast, repast of breakfast, lunch, and supper, number of suppers and night snacks per week, and duration of meal) in 138 female university students residing in Bucheon and its adjacent area. Food habits were assessed via a self reporting questionnaire, and a 3-day dietary recall survey was conducted by interviewing. Dietary variety was assessed by dietary diversity score(DDS), meal balance score(MBS), and dietary variety score(DVS). The average DDS, MBS, and DVS were $3.87{\pm}0.57$, $7.27{\pm}1.48$, and $12.59{\pm}3.14$, respectively. The DDS($2.21{\pm}0.83$) of the breakfast in the group in which the regularity of meal time per week was 5~7 days was significantly higher($p$ <0.01) than the DDS($1.47{\pm}0.96$) of the breakfast in the group in which the regularity of meal time per week was ${\leq}$2 days. The MBS($6.69{\pm}1.43$) of the group in which the regularity of meal times per week was ${\leq}2$ days was significantly lower($p$ <0.01) than the MBS of the group in which the regularity of meal time per week was ${\geq}3$ days. The DDS($2.38{\pm}0.69$) of the breakfast in the breakfast over eating group was significantly higher($p$ <0.001) than the DDS($1.83{\pm}0.83$) of breakfast under eating group. The MBS($6.56{\pm}1.46$) in the breakfast skipping group was significantly lower($p$ <0.01) than the MBS(about 7.6) in other breakfast eating groups, and the DVS ($13.79{\pm}3.21$) in the breakfast over eating group was significantly higher($p$ <0.05) than the DVS($11.53{\pm}2.94$) in the breakfast skipping group. The DDS of breakfast, lunch, and snack were not significantly correlated with the number of suppers per week, but the DDS($2.65{\pm}0.52$) of the supper in the group in which the number of suppers per week was 7 was significantly higher($p$ <0.05) than the DDS($2.22{\pm}0.49$, $2.25{\pm}0.62$) of the supper in the group in which the number of suppers per week was ${\leq}2$, 3~4. The DDS, MBS and DVS were not significantly correlated with the number of suppers per week. The DDS($1.33{\pm}1.25$) of the breakfast in the group in which the number of night snacks per week was 6~7 was significantly lower($p$ <0.05) than the DDS of the breakfast in the group in which the number of night snacks was ${\leq}5$. Also, the DDS($4.42{\pm}0.32$) per day in the group in which the duration of meal was <10 min. was significantly higher($p$ <0.01) than the DDS($3.51{\pm}0.53$) per day in the group in which the duration of meal was ${\geq}30$ min. These findings suggest that nutritional education based on female university students' eating variety and food habits(regularity of meal time, regularity of repast, repast of breakfast, lunch, and supper, number of suppers, and night snacks per week, and duration of meal) may be required to improve dietary variety.