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Effects of Chronic Alcohol Feeding and 2-Acetylaminofluorene Treatment on Microsomal Cytochrome P-450 and Glutathione Dependent Enzymes Activities in Rat Liver (만성 알코올 섭취시 2-Acetylaminofluorene 투여가 흰쥐간 Cytochrome P-450 및 Glutathione 이용 효소계 활성에 미치는 영향)

  • 김정희;최옥희;윤혜진
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.6
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    • pp.859-866
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    • 1995
  • This study was done to investigate the effects of chronic ethanol feeding on hepatic microsomal cytochrome system, lipid peroxidation and peroxide metabolizing enzyme activities in 2-acetylaminofluorene(2-AAF) treated rats. Male Sprague-Dawley rats, weighing 120~125g, were pair-fed liquid diets containing 35% of total calories either as ethanol or isocaloric carbohydrates for 6 weeks. After 4 weeks of experimental diet feeding, 2-AAF(100mg/kg body weight) was injected twice a week intraperitoneally. Both weight and percent liver weight per body weight were significantly changed by ethanol feeding. Hepatic microsomal lipid peroxide value and the activities of glutathione(GSH) peroxidase and GSH reductase were not changed by either ethanol or 2-AAF treatment. However the analysis of cytochrome systems showed that both ethanol and 2-AAF increased cytochrome P-450 and bs contents although cytochrome P-450 content was moe affected by 2-AAF while cytochrome b5 content by ethanol. Cytosolic GSH S-transferase activity, which is often elevated during chemical carcinogenesis, also significantly increased by either ethanol feeding or 2-AAF treatment. Overall values for the cytochrome contents and GSH S-transferase activities were highest in 2-AAF treated rats fed ethanol. These results might support the hypothesis that the increase in liver cancer risk associated with chronic ethanol consumption might be due to, at least in part, enhancement of carcinogen bioactivation by ethanol.

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Performance Evaluation of Premier Global Construction Engineer Training Program (글로벌 건설 엔지니어링 고급인력 양성사업의 성과평가)

  • Park, Hyeon;Park, Inseok
    • Korean Journal of Construction Engineering and Management
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    • v.19 no.3
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    • pp.97-104
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    • 2018
  • This paper aims to evaluate the performance of S University's Premier Global Construction Engineer Training Program. The net impact of the program is evaluated through a quasi-experiment design approach. The competency level of an individual participant is compared with that of a non-participating expert with similar professional background. The results show that the training program contributed to a significant improvement in the professional competencies of the participating students. The competency level was regressed on the subjects of curriculum. The achievements are attributable to a group of subjects focused on the skills for project development such as PPP, feasibility study, and project financing. Another group of subjects found to have significantly contributed to the improved competencies can be categorized as subjects focused on nurturing global perspectives. The paper shows it is possible to quantify the contribution of the program and the results provide a set of information that can be useful in designing and operating similar programs.

Direct Bonding of SillSiO2/Si3N4llSi Wafer Fairs with a Fast Linear Annealing (선형가열기를 이용한 SillSiO2/Si3N4llSi 이종기판쌍의 직접접합)

  • 이상현;이상돈;송오성
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.15 no.4
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    • pp.301-307
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    • 2002
  • Direct bonded SOI wafer pairs with $Si ll SiO_2/Si_3N_4 ll Si$ the heterogeneous insulating layers of SiO$_2$-Si$_3$N$_4$are able to apply to the micropumps and MEMS applications. Direct bonding should be executed at low temperature to avoid the warpage of the wafer pairs and inter-diffusion of materials at the interface. 10 cm diameter 2000 ${\AA}-SiO_2/Si(100}$ and 560 $\AA$- ${\AA}-Si_3N_4/Si(100}$ wafers were prepared, and wet cleaned to activate the surface as hydrophilic and hydrophobic states, respectively. Cleaned wafers were pre- mated with facing the mirror planes by a specially designed aligner in class-100 clean room immediately. We employed a heat treatment equipment so called fast linear annealing(FLA) with a halogen lamp to enhance the bonding of pre mated wafers We kept the scan velocity of 0.08 mm/sec, which implied bonding process time of 125 sec/wafer pairs, by varying the heat input at the range of 320~550 W. We measured the bonding area by using the infrared camera and the bonding strength by the razor blade clack opening method, respective1y. It was confirmed that the bonding area was between 80% and to 95% as FLA heat input increased. The bonding strength became the equal of $1000^{\circ}C$ heat treated $Si ll SiO_2/Si_3N_4 ll Si$ pair by an electric furnace. Bonding strength increased to 2500 mJ/$\textrm{m}^2$as heat input increased, which is identical value of annealing at $1000^{\circ}C$-2 hr with an electric furnace. Our results implies that we obtained the enough bonding strength using the FLA, in less process time of 125 seconds and at lowed annealing temperature of $400^{\circ}C$, comparing with the conventional electric furnace annealing.

A Polarization-Switchable Microstrip Patch Antenna Using Corner Slots on Ground Plane and PIN Diodes (모서리 접지면 슬롯과 PIN 다이오드를 이용한 편파 변환 마이크로스트립 안테나)

  • Park, Chul-Woo;Lee, Tae-Hak;Choi, Jun-Ho;Yoon, Won-Sang;Pyo, Seong-Min;Kim, Young-Sik
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.7
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    • pp.769-777
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    • 2010
  • In this paper, a switchable circularly polarized microstrip patch antenna using PIN diodes and corner slots on ground plane is proposed at 2.4 GHz. The proposed antenna has a square microstrip patch and ground plane that consists of two pair of slots and PIN diodes. The electrical lengths of the slots are adjusted by using the switching characteristic of the PIN diode, so the polarization of the proposed antenna can be switchable between linear, left-handed(LH) and right-handed(RH). By separating the ground plane for the DC bias, the size reduction effect is also obtained. When the proposed antenna is operated as linear polarization, the return loss and impedance bandwidth are 15 dB, 59 MHz, and when operated as LH and RH polarization, the minimum axial ratio and 3-dB axial ratio bandwidth are 1.17 dB, 1.67 dB, 28 MHz, and 32 MHz, respectively.

Prediction of Transmission Error Using Dynamic Analysis of a Helical Gear (헬리컬기어의 동적해석을 통한 전달오차 예측)

  • Lee, Jeongseok;Yoon, Moonyoung;Boo, Kwangsuk;Kim, Heungseob
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.12
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    • pp.1005-1011
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    • 2016
  • The fundamental reason for gear noise is transmission error. Transmission error occurs because of STE (static transmission error) and DTE (dynamic transmission error), while a pair of gears is meshing. These errors are generated by the deflection of the teeth and the friction on the surface of the teeth. In addition, the vibration generated by transmission error leads to excited bearings. The bearings support the shafts, and the noise is radiated after exciting the gear casing. The analysis of the contact stress in helical gear tooth flanks indicates that it is due to impact loading, such as the sudden engagement and disengagement of a gear. Stress analysis is performed for different roll positions, in order to determine the most critical roll angle. Dynamic analysis is performed on this critical roll position, in order to evaluate variation in stresses and tooth contact force, with respect to time. In this study, transmission error analysis was implemented on a spur and helical gear with involute geometry and a modified geometry profile. In addition, in order to evaluate the intensity of impact due to sudden engagement and significant backlash, the impact factor was calculated using the finite element analysis results of static and dynamic maximum bending stresses.

A Method for Detection of Private Key Compromise (서명용 개인키 노출 탐지 기법)

  • Park, Moon-Chan;Lee, Dong-Hoon
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.24 no.5
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    • pp.781-793
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    • 2014
  • A Public Key Infrastructure (PKI) is security standards to manage and use public key cryptosystem. A PKI is used to provide digital signature, authentication, public key encryption functionality on insecure channel, such as E-banking and E-commerce on Internet. A soft-token private key in PKI is leaked easily because it is stored in a file at standardized location. Also it is vulnerable to a brute-force password attack as is protected by password-based encryption. In this paper, we proposed a new method that detects private key compromise and is probabilistically secure against a brute-force password attack though soft-token private key is leaked. The main idea of the proposed method is to use a genuine signature key pair and (n-1) fake signature key pairs to make an attacker difficult to generate a valid signature with probability 1/n even if the attacker found the correct password. The proposed method provides detection and notification functionality when an attacker make an attempt at authentication, and enhances the security of soft-token private key without the additional cost of construction of infrastructure thereby extending the function of the existing PKI and SSL/TLS.

A Study on the Relationship between Images of Colors Derived from Plants and Color Names

  • Masuda, Kinuko;Iwasaki, Yutaka
    • Proceedings of the Korean Institute of Landscape Architecture Conference
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    • 2007.10b
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    • pp.78-83
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    • 2007
  • The colors have a close to our life and there are many color names derived from plants in Japan. This study aimed to analyze relationship people and plants and investigated what the images of colors derived from plants related to the color names. Surveys on color images of abstract and concrete were conducted with adults who lived in the metropolitan area and in urban areas. The subjects were surveyed about images of similar colors derived from plants(3 type of similar two colors; pink, green and yellow) and asked to select a pair of color names(momo or pink, midori or green, yamabuki or lemon) corresponding to the color. The subjects were simultaneously presented with two similar colors and asked to give their perceptions of each color against 13 polar opposite pairs of terms or phrases using a Semantic Differential Scale, and asked to select the number of the 16 items concerned with life such as clothes and food. With the pink colors, many subjects did not feel opposite abstract images between these two similar colors and felt the same concrete images such as 'cosmetics' and 'clothes', and these color names such as momo and pink are confused. With the green colors and the yellow colors, many subjects felt opposite abstract images between these two similar colors such as 'natural - artificial' and 'rural - urban' and different concrete images such as 'plants' and 'plastics', and these two similar colors are distinguished by the color names such as 'midori - green' and 'yamabuki - lemon'. The results revealed that there are two patterns in the relationship colors derived from plants, color images and color names. In the pattern which images of colors derived from plants are connected with artificial things irrelevant to plants, the color names corresponding to the two similar colors are confused. On the other hand, in the pattern which images of colors derived from plants are connected with plants and artificial things, the two similar colors are distinguished by their color names. So demographics influenced the images of color, younger subjects compared with older tend to obviously distinguish images of colors derived from plants, and there are images of color influenced by the environment as a child. In both patterns, images of colors derived from plants are influenced by artificial things and natural colors are limited among many people. These results indicate that there are a few opportunities to see colors of plants which are full of variety. These results suggest that it is necessary to recognize colors derived from plants in relation to plants and to educate regarding the nature of plants, therefore landscape architecture focused on colors of plants is required.

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A Predictive Algorithm using 2-way Collaborative Filtering for Recommender Systems (추천 시스템을 위한 2-way 협동적 필터링 방법을 이용한 예측 알고리즘)

  • Park, Ji-Sun;Kim, Taek-Hun;Ryu, Young-Suk;Yang, Sung-Bong
    • Journal of KIISE:Software and Applications
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    • v.29 no.9
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    • pp.669-675
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    • 2002
  • In recent years most of personalized recommender systems in electronic commerce utilize collaborative filtering algorithm in order to recommend more appropriate items. User-based collaborative filtering is based on the ratings of other users who have similar preferences to a user in order to predict the rating of an item that the user hasn't seen yet. This nay decrease the accuracy of prediction because the similarity between two users is computed with respect to the two users and only when an item has been rated by the users. In item-based collaborative filtering, the preference of an item is predicted based on the similarity between the item and each of other items that have rated by users. This method, however, uses the ratings of users who are not the neighbors of a user for computing the similarity between a pair of items. Hence item-based collaborative filtering may degrade the accuracy of a recommender system. In this paper, we present a new approach that a user's neighborhood is used when we compute the similarity between the items in traditional item-based collaborative filtering in order to compensate the weak points of the current item-based collaborative filtering and to improve the prediction accuracy. We empirically evaluate the accuracy of our approach to compare with several different collaborative filtering approaches using the EachMovie collaborative filtering data set. The experimental results show that our approach provides better quality in prediction and recommendation list than other collaborative filtering approaches.

Virtual Target Overlay Technique by Matching 3D Satellite Image and Sensor Image (3차원 위성영상과 센서영상의 정합에 의한 가상표적 Overlay 기법)

  • Cha, Jeong-Hee;Jang, Hyo-Jong;Park, Yong-Woon;Kim, Gye-Young;Choi, Hyung-Il
    • The KIPS Transactions:PartD
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    • v.11D no.6
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    • pp.1259-1268
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    • 2004
  • To organize training in limited training area for an actuai combat, realistic training simulation plugged in by various battle conditions is essential. In this paper, we propose a virtual target overlay technique which does not use a virtual image, but Projects a virtual target on ground-based CCD image by appointed scenario for a realistic training simulation. In the proposed method, we create a realistic 3D model (for an instructor) by using high resolution Geographic Tag Image File Format(GeoTIFF) satellite image and Digital Terrain Elevation Data (DTED), and extract the road area from a given CCD image (for both an instructor and a trainee). Satellite images and ground-based sensor images have many differences in observation position, resolution, and scale, thus yielding many difficulties in feature-based matching. Hence, we propose a moving synchronization technique that projects the target on the sensor image according to the marked moving path on 3D satellite image by applying Thin-Plate Spline(TPS) interpolation function, which is an image warping function, on the two given sets of corresponding control point pair. To show the experimental result of the proposed method, we employed two Pentium4 1.8MHz personal computer systems equipped with 512MBs of RAM, and the satellite and sensor images of Daejoen area are also been utilized. The experimental result revealed the effective-ness of proposed algorithm.

Luminescence Characteristic of CNT Element in ZnS:(Cu, Al) Thin Film Fabricated by a Screen Printing Method (스크린 프린팅 방법으로 제작한 ZnS:(Cu, AL) 박막의 CNT 불순물 첨가에 의한 광학적 특성에 관한 연구)

  • Shon, Pong-Kyun;Shin, Jun-Ha;Bea, Jae-Min;Lee, Jae-Bum;Kim, Jong-Su;Lee, Sang-Nam
    • Journal of the Korean Graphic Arts Communication Society
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    • v.29 no.1
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    • pp.23-33
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    • 2011
  • This experimental focus to characterize luminescence properties related to CNT (Carbon Nano Tube) element dispersedly implanted in ZnS-based phosphor thin film panel fabricated by a screen printing method. More specifically FE-SEM measurements, L-V(Luminescence vs. Voltage) and photo luminescence were carried out to determine an optimum value of CNT concentration and film thickness for the thin film structure of CNT-ZnS:(Cu, Al) by the screen printing method. We confirmed that an optimum value of CNT concentration in the ZnS:(Cu, Al) film panel is about 0.75 wt% resulting that the electric conductivity is 1.6 times higher than that of pure CNT sample and showing that the luminescence intensity is increasing until the optimum concentration. Clearly, CNT is presenting in the luminescence process providing a pathway for the creation of hot electron and a channel for the electron-hole recombination but overly inserted CNT may hinder to produce the hot electron for making an avalanching process. In case of the overly doped CNT 1.0 wt% in the ZnS-based phosphor, the luminescence intensity is decreasing although the electric conductivity is exponentially increasing. Based on these results, we realized that hot electron occurred by the external electric field or exciton arose by the external photon source are reduced dramatically over the critical value of CNT concentration because CNT element provide various isolated residues in the composites of ZnS based phosphor rather than pathway or channel for the D-A(Donnor to Acceptor) pair transition or the radiative recombination of electron-hole.