• Title/Summary/Keyword: P-I 선도

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In the Treatment I-131, the Significance of the Research that the Patient's Discharge Dose and Treatment Ward can Affect a Patient's Kidney Function on the Significance of Various Factors (I-131 치료시 환자의 신장기능과 다양한 요인으로 의한 퇴원선량 및 치료병실 오염도의 유의성에 관한 연구)

  • Im, Kwang Seok;Choi, Hak Gi;Lee, Gi Hyun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.62-66
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    • 2013
  • Purpose: I-131 is a radioisotope widely used for thyroid gland treatments. The physical half life is 8.01 and characterized by emitting beta and gamma rays which is used in clinical practice for the purpose of acquiring treatment and images. In order to reduce the recurrence rate after surgery in high-risk thyroid cancer patients, the remaining thyroid tissue is either removed or the I-131 is used for treatment during relapse. In cases of using a high dosage of radioactive iodine requiring hospitalization, the patient is administered dosage in the hospital isolation ward over a certain period of time preventing I-131 exposure to others. By checking the radiation amount emitted from patients before discharge, the patients are discharged after checking whether they meet the legal standards (50 uSv/h). After patients are discharged from the hospital, the contamination level is checked in many parts of the ward before the next patients are hospitalized and when necessary, decontamination operations are performed. It is expected that there is exposure to radiation when measuring the ward contamination level and dose check emitted from patients at the time of discharge whereby the radiation exposure by health workers that come from the patients in this process is the main factor. This study analyzed the correlation between discharge dose of patients and ward contamination level through a variety of factors such as renal functions, gender, age, dosage, etc.). Materials and Method: The study was conducted on 151 patients who received high-dosage radioactive iodine treatment at Soon Chun Hyang University Hospital during the period between 8/1/2011~5/31/2012 (Male: Female: 31:120, $47.5{\pm}11.9$, average dosage of $138{\pm}22.4$ mCi). As various factors expected to influence the patient discharge dose & ward contamination such as the beds, floors, bathroom floors, and washbasins, the patient renal function (GFR), age, gender, dosage, and the correlation between the expected Tg & Tg-Tb expected to reflect the remaining tissue in patients were analyzed. Results: In terms of the discharge dose and GFR, a low correlation was shown in the patient discharge dose as the GFR was higher (p < 0.0001). When comparing the group with a dosage of over 150mCi and the group with a lower dosage, the lower dosage group showed a significantly lower discharge dose ($24{\pm}10.4uSv/h$ vs $28.7{\pm}11.8uSv/h$, p<0.05). Age, gender, Tg, Tg-Tb did not show a significant relationship with discharge dose (p> 0.05). The contamination level in each spot of the treatment ward showed no significant relationship with GFR, Tg, Tg-Tb, age, gender, and dosage (p>0.05 ). Conclusion: This study says that discharge of the dose in the patient's body is low in GFR higher and Dosage 150mCi under lower. There was no case of contamination of the treatment ward, depending on the dose and renal association. This suggests that patients' lifestyles or be affected by a variety of other factors.

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Synthesis and Luminescent Characteristics of Anthracene Fluoroionophores (안트라센 형광 단위를 가지는 Fluoroionophore의 합성 및 발광특성)

  • Jeon Young-Min;Kim Jong-Gyu;Jang Ji-Geun;Chang Ho-Jung;Kim Yung-Sup;Gong Myoung-Seon
    • Polymer(Korea)
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    • v.30 no.5
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    • pp.426-431
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    • 2006
  • Novel azacrown ether containing blue -light emitting anthracene fluorophore, 9,10-bis [p-(1-aza-18-crown-6)methylphenyl] anthracene (3) and N,N-bis [9-(p-methylphenyl) anthracenyl-methyl] -1,6-diaza-18-crown-6 (4) were prepared by reacting anthracene derivatives 1 and 2 with mono- and diaza-18-crown-6, respectively Also, crown ether containing fluorophore copolymer (5) were prepared by reacting 1,6-diaza-18-crown-6 with 1. Their fluorescence emission spectral studies were investigated by binding group I, group II and various metal cations. The fluorophores showed an absorption at ${\lambda}_{max}$= 372 nm and an emission at ${\lambda}_{max}$= 430 nm. pH Dependency of fluorescence emission intensity were examined to determine the optimum pH for the fluorophores.

Effects of the Thyroid Function on the Adrenal Gland, Hypophysis and Gonads in the Guinea Pigs. 1 Effects of the Thyroid Function on the Adrenal Gland in the Guinea Pigs (Guinea pig의 갑상선기능(甲狀腺機能)이 부신(副腎), 뇌하수체(腦下垂體) 및 생식선(生殖腺)에 미치는 영향(影響) I. Guinea pig의 갑상선(甲狀腺)이 부신(副腎)에 미치는 영향(影響))

  • Lee, Kang Wook;Lee, Kyu Sung;Cheong, Young Chai
    • Korean Journal of Veterinary Research
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    • v.8 no.2
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    • pp.110-116
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    • 1968
  • The mature guinea pigs were grouped as indicated in the table 1. Radio-active iodine(I-131)in dose of 4.5mci, was administered to the experimental groups. The animals were killed for examination in 1, 7, 14, 28, 42, and 55 days after the administration the radio-active iodine. The thyroid and adrenal glands were observed histologically. The results obtained were as follows; 1. One day after the administration, thyroid epithelial cells were abnormally enlarged. After seven days, specimens taken from the middle of the thyroid showed that the follicles and epithelial cells were changing to fibrous tissue, however, some follicles still remained in the verge of the thyroid. Follicles were not observed after fourteen days. After twenty-eight days, the follicles had all changed to fibrous tissue, and had lost their function. 2. The size of the zonas gromerulosa of adrenal cortex epually, in both male and female, showed slight fluctuation in size with no tendency to be changed. 3. Among the zones of the adrenal glands, zona fasciculata showed marked changes. Zona fasciculata was atrophied in Process of time. In females, it was atrophied significantly(P<0.05) after fourteen days, and highly significant (P<0.01) in twenty-eight and fifty-six days after the administration of radioactive iodine. In males, it also decreased significantly(P<0.05) in seventy-eight days and highly significant(P<0.01) in forty-two and fifty-six days after the administration. 4. The size of the Zona reticularis of adrenal cortex in the females increased significantly (P<0.05) in twenty-eight days after the administration. In males, it showed slight fluctuation until twenty-eight days, but it increased significantly(P<0.05) in forty-two and fifty-six days after the administration. 5. The size of the adrenal medulla increased significantly(P<0.05) in twenty-eight and forty-two days in females. It was increased significantly(P<0.05) in fourth-two days and high significantly(P<0.01) in fifty-six days after the administration.

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Effects of Cryosurgery of the Third Eyelid Gland on Tear Production and Histological Changes in Dogs (개에서 제3안검선 냉동수술이 눈물생산량 및 조직학적 변화에 미치는 영향)

  • 서강문;공인주
    • Journal of Veterinary Clinics
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    • v.17 no.1
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    • pp.121-128
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    • 2000
  • The effects of cryosurgery on tear production and histological changes of the third eyelid were studied in dogs. Clinically normal 12 mixed breeds weighing 2∼6 kg were divided into three groups and treated as follows; 45 seconds double freeze-thaw treated group, 60 seconds double freeze-thaw treated group and 90 seconds double freeze-thaw treated group. The significant decrease of the tear production after cryosurgery was shown in all groups throughout the observed periods(p<0.05). However, there was no difference among groups. The main complications after cryosurgery were chemosis and conjunctival injection. Other complications such as eyelid edema, eyelid depigmentation and keratitis were more preominent in group III compared to those of groups I and II. On histopathological examination, chronic inflammatory changes and regeneration of the third eyelid glands were noted in group I and predominated loss of the third eyelid glands and necrosis of hyaline cartilage were observed in group III However, such changes were less appeared in group II. The results of this study suggested that double freeze-thaw cryosurgery for 60 seconds on the third eyelid glands would be the most effective method for treating tear staining syndrome.

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Spectral Electromyographic Fatigue Analysis of Back Muscles in Healthy Adult Men and Women During Sorensen Test (근전도를 이용한 Sorensen 검사시 성인남녀 등 근육의 근피로도 분석)

  • Lee, Mi-Seon;Kim, Tae-Young
    • Physical Therapy Korea
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    • v.5 no.3
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    • pp.63-71
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    • 1998
  • Trunk holding test (Sorensen test) appear to have more value than strength test in prediction the occurrence of low back pain. Electromyographic activity of trunk extensor muscles during these test may provide clues to the etiology of neuromuscular-based low back pain. This study investigated the difference in back muscle endurance between healthy adult men and women using surface electromyographic (EMG) power spectral analysis. Thirty hea1thy subjects (15 men and 15 women) performed an unsupported trunk holding test for 60 seconds. Recording surface electrodes were placed over the erector spinae medially and laterally at vertebral levels of $L_1$ and $L_5$. Slope of total frequency was evaluated using the MP100WSW Fast Fourier Transform spectrum analysis program. The slopes of all indices of back muscle fatigue, except right $L_5$, were significantly steeper in men than in women (p<0.05). Our results indicated that the trunk holding test using EMG power spectral analysis of erector spinae muscles is useful for the evaluation of fatigue rate of these muscles. Our results also showed a higher muscle endurance in healthy adult women than in men.

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Correlation of hypoechogenic lesions with lactic dehydrogenase isoenzymes, culture and cytological findings of prostatic fluid and bilpsied tissue in dogs (개에서 전립선액과 생검조직에 대한 젖산탈수소 효소치, 배양 및 세포학적 검사와 초음파상의 저에코 영역과의 연관성)

  • Eom, Ki-dong;Yoon, Jung-hee;Sung, Jai-ki
    • Korean Journal of Veterinary Research
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    • v.38 no.3
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    • pp.664-673
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    • 1998
  • 초음파학적 검사에 따라 미만성 저에코 영역, 낭포, 다병소성 낭포 및 비후된 피막 등 비정상적 소견을 보이는 전립선에서 추출한 전립선액과 생검조직에서의 LDH 분획비(LDH I/V)의 평균치는 각각 $0.92{\pm}0.55$, $2.69{\pm}0.82$, 정상군(각각 $0.23{\pm}0.20$, $0.57{\pm}0.36$)에 비하여 유의성(p<0.01) 있게 높았다. 세포병리학적 검사에서 전립선 비대증 및 전립선염으로 나타난 비정상군($2.76{\pm}0.77$의 생검조직 LDH 평균분획비는 정상군($1.38{\pm}1.19$)에 비해 유의성 있게 높았으나 전립선액에서는 분획비의 유의차가 인정되지 않았다. 배양결과에 따른 전립선액 및 조직시료의 LDH 분획비는 정상군과 비정상군 사이에서의 유의성은 인정되지 않았다. 결론적으로 저에코 영역 및 낭포부위는 생검조직과 전립선액의 배양 및 세포병리학적 검사에 따른 비정상성 및 높은 LDH 분획비와 밀접한 연관성을 보였다. 특히 경직장 초음파상에 나타나는 미만성 저에코 영역은 전립선 비대증 및 만성 전립선염 등과 같은 병적 관련성을 내포하고 있는 것으로 사료된다.

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Adsorption and Oxidation of Polychlorinated Phenols onto Transition Metal Oxides (I). Adsorption Characteristics and Reductive Dissolution of ${\sigma}-MnO_2$(s) (전이금속산화물에 대한 다염소치환페놀류의 흡착과 산화 (제 1 보). ${\sigma}-MnO_2$(s)의 흡착특성과 환원성 용해)

  • Jong Hoon Yun;Jong Wan Lim;Heung Lark Lee;Sang Oh Oh;Sun Haing Lee
    • Journal of the Korean Chemical Society
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    • v.35 no.3
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    • pp.226-232
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    • 1991
  • Adsorption and oxidation of polychlorinated phenols by suspended ${\sigma}-MnO_2$ in aqueous solution have been studied. Of the proposed mechanism, adsorption reaction of chlorophenols onto ${\sigma}-MnO_2$(s) depended upon the pH of the solution and the concentration of chlorophenol. Adsorption isotherms showed a reasonably good fit to the Langmuir isotherm. From the pH dependence of adsorption partition coefficient and the linear relationship between octanol-water partition coefficient and adsorption partiton coefficient of chlorophenol, it is estimated that adsorption is dominated by its hydrophobicity. The rate of electron transfer reaction evaluated from the rate of reductive dissolution of ${\sigma}-MnO_2$(s) depended linearly upon the concentration of chlorophenol and the pH of medium. Observed rate constants ($K_0$) of the meta-substituted chlorophenol were lower than that of the ortho-or para-chlorophenol because of resonance effect of chlorophenoxy radical. It is indicated that this radical is produced in the adsorption process and the electron transfer reaction is rate determining.

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Flashover Characteristics of Damaged Insulator Strings for Live-line works in 765kV T/L (765kv 송전선로 활선작업을 위한 불량애자 발생 유형별 전기적 섬락특성 분석)

  • Lee, H.K.;Shon, H.K.;Park, M.Y.;Park, I.P.;Kim, H.J.
    • Proceedings of the KIEE Conference
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    • 2005.05b
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    • pp.31-34
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    • 2005
  • The 765kV transmission line will be maintained by live-line works for efficient operation, In order to maintain the 765kV transmission lines safely by live-line works, lineman have to know flashover characteristics of the insulator strings with damaged insulators. This paper suggests flashover characteristics of the 765kV insulator strings from experimental test results directly.

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후열 처리 조건에 따른 a-Si/c-Si 이종접합 태양전지 특성 분석

  • Kim, Kyung Min;Jeong, Dae Young;Song, Jun Yong;Kim, Chan Seok;Koo, Hye Young;Oh, Byung Sung;Song, Jinsoo;Lee, Jeong Chul
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.58.2-58.2
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    • 2010
  • 본 연구에서는 n-type wafer에 비정질 실리콘을 증착한 이종접합 태양전지를 열처리 방법을 이용하여 열처리의 효과를 분석함으로써 이종접합 태양전지에 효율적인 열처리 효과에 대하여 연구하였다. P, N-layer는 PECVD(Plasma-enhanced chemical vapor deposition) I-layer는 HWCVD(Hot wire chemical vapor deposition), ITO는 RF 마그네트론 스퍼터링법으로 동일한 조건에서 제작하였고 rapid thermal process를 이용하여 진공 중에서 $150^{\circ}C$, $200^{\circ}C$, $220^{\circ}C$, $250^{\circ}C$까지 열처리를 하였다. 열처리 전과 후 QSSPC로 minority carrier life time, 자외 가시선 분광분석 장치로 투과 반사도를, Ellipsometer로 흡수 계수 등의 변화를 조사하였다. 열처리 후 Minority carrier life time, Voc 및 광변환 효율이 증가하였다.

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Neutral Current Calculation of the One Step Type Pole using KEPCO's Distribution System (한전 실 배전계통 모델을 이용한 1단 장주 중성선 전류 계산)

  • Seo, H.C.;Park, K.W.;Kim, C.H.;Jung, C.S.;Yoo, Y.P.;Lim, Y.H.;Seol, I.H.
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.1
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    • pp.35-40
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    • 2007
  • The one step type and two step type pole are used in distribution line. If the three phases are not balanced, the communication line can be damaged by induced voltage. This paper calculates the neutral current using KEPCO's distribution system model which is only composed by one step type pole. The used system model is modelled by using ATPDraw and the neutral current is calculated by using EMTP/MODELS. Many cases for abstracting the neutral current characteristics in KEPCO's distribution system are simulated and analyzed.