• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 하계학술대회 논문집 C
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• pp.1437-1439
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• 1995

This paper investigates the effect of thermal oxidation on the profile of the residual stress along the depth of p+ silicon films by quantitative determination method. Two examples for the application of this method illustrate that most of p+ region is subjected to the tensile stress except the region near the front surface and that the stress gradient of the film oxidized at $1100^{\circ}C$ is more steep than that of the film oxidized at $1000^{\circ}C$.

• Nutritional Sciences
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• 제5권4호
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• pp.228-233
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• 2002

The low molecular weight zinc-binding protein metallothionein(MT) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over- or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress. Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

• 한국영양학회:학술대회논문집
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• 한국영양학회 2002년도 추계 심포지움초록
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• pp.1171-1177
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• 2002

The low molecular weight zinc-binding protein metallothionein (MT) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over-or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

• 한국영양학회:학술대회논문집
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• 한국영양학회 2002년도 추계학술대회 및 총회
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• pp.73-82
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• 2002

The low molecular weight zinc-binding protein metallothionein (U) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over- or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress. Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

• Journal of Ecology and Environment
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• 제29권1호
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• pp.61-67
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• 2006

Tomato (Lycopersicon esculentum Mill) seedlings exposed to various concentrations of $CdCl_2(0{\sim}100{\mu}M)$ in a nutrient solution for up to 9 days were analyzed with respect to the thiol changes and oxidative stress. The Cd exposure increased total non-protein thiols (NPT) and cysteine in both leaves and roots, total glutathione in leaves, and the ratios of oxidized glutathione (GSSG)/reduced glutathione (GSH) in both leaves and roots, but decreased the ratio of dehydroascorbate (DASA)/ascorbate(ASA) in leaves. Our results suggest that the Cd-induced GSH depletion due to thiol synthesis and oxidation alters the antioxidant activity of seedlings for $H_2O_2$, and the subsequent $H_2O_2$ accumulationand oxidative stress result in phytotoxicity.

• 한국재료학회:학술대회논문집
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• 한국재료학회 1996년도 재료학회 추계학술발표회
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• pp.6-6
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• 1996

• Nuclear Engineering and Technology
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• 제21권2호
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• pp.89-98
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• 1989

지르칼로이 -4 피복관에 대해서 3가지 변형 속도로(1.2$\times$10E-7/s, 2.0$\times$10E-6/s, 3.2$\times$10E -5/s), 553-873K의 온도 구간에서 구리 맨드렐 팽창 시험법을 공기와 진공(5$\times$10E-5 torr) 분위기에서 수행했고, 변형 속도의 변화는 시편의 가열 속도를 조절함으로써 얻을 수 있었다. 각각의 변형 속도에서 항복 응력 피크와 변형 속도 감도 최저값 그리고 활성화 부피 극대값이 나타나는 이유는 동적변형시효 현상 때문이라고 설명된다. 항복 응력 피크가 나타나는 온도와 변형속도로부터 얻어진 동적변형시효의 활성화 에너지는 196(KJ/mol)이었고 이 값은 $\alpha$-지르코니움과 지르칼로이-2에서 활성화 에너지(207-220 KJ/mol)값과 잘 일치한다. 그러므로 573-673K의 온도 구간에서 나타나는 동적변형시효 현상은 산소원자 때문이라고 생각된다. 산화에 의한 항복 응력의 증가는 공기중 실험과 진공 실험으로 얻어진 항복 응력값을 비교함으로서 얻었고, 그것은 항복 응력의 증가 분율로 표시했다. 결과는 변형속도가 느릴 수록 증가 분율은 더욱 더 커짐을 알 수 있었다. 그리고 산소 침투량과 항복 응력 증가 사이의 관계가 직선적이라는 가정하에 공기와 수중에서의 산화 속도를 비교하여 수중에서의 항복 응력 값을 계산해 보았다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3663-3667
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• 2013

Background: Multiple myeloma is a malignant silent incurable plasma cell disorder. The present study aimed to assessed the activation of the oxidative stress pathway in afected patients Materials and Methods: Advanced oxidation protein products (AOPPs), malondialdehyde (MDA), adenosine deaminase (ADA), total antioxidant capacity (TAC) levels, glutathione, ascorbic acid (vitamin C), ${\alpha}$-tocopherol (vitamin E) in addition to related enzymes glutathione peroxidase (GSH-Px), glutathione reductase (GSH-R) and superoxide dismutase (SOD) were analyzed in sixty patients with multiple myeloma before and after one month treatment with induction therapy. Results: The results of the study showed a significant elevation in AOPPs, MDA, ADA levels in patients with multiple myeloma before and after treatment in comparison to healthy control samples In contrast TAC glutathione, vitamin C and E, and the antioxidant enzymes levels were decreased significantly. On comparing samples of MM patients after treatment, there was significant increase of TAC glutathione, vitamin C and E, and the antioxidant enzymes in parallel with decreasing AOPPs, MDA and ADA levels in comparison with samples of patients before treatment. Conclusions: The results indicate oxidative stress and DNA damage activity increase in MM and are alleviated in response to therapy.

• 대한전자공학회논문지
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• 제25권11호
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• pp.1304-1314
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• 1988

Porous실리콘 形成反應에서 HF濃度, 電流應度, 反應時間 및 基叛의 表面狀態가 PSL (Porous Silicon Layers)의 porosity에 미치는 影響을 실험적으로 조사하였다. PSL을 陽배化 시켜서 室溫에서 FIPPOS-SOI를 제조하는 방법을 연구하였다. 이 방법으로 100um폭의 SOI strip line을 제조하였으며 SOI의 stress제거를 위해 2단계 PSL 형성법을 이용하였다. 또한 이 실온 SOI 제조기술을 이용하여 이미 소자공정을 끝낸 집적회로를 SOI화 시킬 수 있는 방법을 제안하였다.

• BMB Reports
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• 제29권6호
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• pp.513-518
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• 1996

A soluble protein from Saccharomyces cerevisiae specifically provides protection against a thiolcontaining oxidation system but not against an oxidation system without thiol. This 25-kDa protein was thus named thiol-dependent protector protein (TPP). The role of TPP in the cellular defense against oxidative stress was investigated in Escherichia coli containing an expression vector with a yeast genomic DNA fragment that encodes TPP (strain YP) and a mutant in which the catalytically essential amino acid in the active site of TPP (Cys-47) has been replaced with alanine by site-directed mutagenesis (strain YPC47A). There was a distinct difference between these two strains in regard to viability, modulation of activities of superoxide dismutase and catalase, and the oxidative damage of DNA upon exposure to menadione. These results suggest that TPP may play a direct role in the cellular defense against oxidative stress by functioning as an antioxidant protein.