• 제목/요약/키워드: One-pot

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Silica Supported Tungstosilicic Acid as an Efficient and Reusable Catalyst for the One-Pot Synthesis of β-Acetamido Ketones via a Four-Component Condensation Reaction

  • Nasr-Esfahani, Masoud;Montazerozohori, Morteza;Gholampour, Tahere
    • Bulletin of the Korean Chemical Society
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    • 제31권12호
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    • pp.3653-3657
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    • 2010
  • Silica supported tungstosilicic acid has been used as an effective catalyst for a modified Dakin-West one-pot, four-component condensation of an aryl aldehyde, an aryl ketone, acetyl chloride and acetonitrile for the synthesis of $\beta$-acetamido ketones. This catalytic system can act as an active, inexpensive, recoverable and recyclable catalyst. Some advantages of this system are short reaction times, good to excellent yields, easy work up and the ability to be carried out at the large scale reactions.

Applications of Cross-linked Poly(4-vinylpyridine/styrene) Copolymer supported Ytterbium(III) Triflate in Mannich-type Reaction:Three Component One-pot Synthesis of β-Aminoketones

  • Lee, Sang-Hyeup;Lee, Byoung-Se
    • Bulletin of the Korean Chemical Society
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    • 제30권3호
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    • pp.551-555
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    • 2009
  • The ytterbium catalyst immobilized on the cross-linked poly(4-vinylpyridine/styrene) copolymer (P/S-Yb) was applied in the Mannich-type, three component one-pot synthesis of $\beta$-aminoketones. This catalytic system showed excellent catalytic activity and selectivity which resulted in the exclusive formation of $\beta$-aminoketone. The applicability of this immobilized catalyst system was shown by the reusability test and again highlighted by the synthesis of a $\beta$-aminoketone library using a broad range of substrates.

A Fast, Highly Efficient and Green Protocol for One-Pot Synthesis of 2,4,5-Trisubstituted Imidazoles Catalyzed by [TBA]2[W6O19] as a Reusable Heterogeneous Catalyst

  • Ashrafi, Mozhgan;Davoodnia, Abolghasem;Tavakoli-Hoseini, Niloofar
    • Bulletin of the Korean Chemical Society
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    • 제34권5호
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    • pp.1508-1512
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    • 2013
  • A simple and efficient synthesis of 2,4,5-trisubstituted imidazoles was achieved via a one-pot three-component cyclocondensation of benzil, aromatic aldehydes, and ammonium acetate in the presence of a catalytic amount of tetrabutylammonium hexatungstate $[TBA]_2[W_6O_{19}]$ as a heterogeneous catalyst under thermal solvent-free conditions. The key features of this methodology are operational simplicity, high yields, short reaction times, and a recyclable catalyst with a very easy work up.

Oxidative Cyclisation Based One-Pot Synthesis of 3-Substituted[1,2,4]triazolo[4,3-b]pyridazines Using Me4NBr/Oxone

  • Ruso, Jayaraman Sembian;Nagappan, Rajendiran;Kumaran, Rajendran Senthil
    • 대한화학회지
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    • 제57권5호
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    • pp.606-611
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    • 2013
  • A facile one-pot syhthesis of 3-substituted triazolopyridazine and thieno-triazolopyridazine derivatives is described. This protocol involves the preparation of heteroaryl hydrazone from the aldehyde and pyridazinohydrazine derivative followed by subjecting the intermediate directly to oxidative cyclization to assemble the desired 1,2,4-triazloe moiety by employing the mixture of Me4NBr and oxone. This condition is efficient and is able to tolerate wide range of functional groups.

지진격리설계된 RC교각의 유사동적 실험 (Pseudo Dynamic Test of the Seismically Isolated RC Piers)

  • 김영진;곽임종;조창백;곽종원
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2004년도 추계 학술발표회 제16권2호
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    • pp.25-28
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    • 2004
  • Many highway bridges in Korea need seismic retrofit because only one decade has passed since the seismic design criteria was introduced. In this experimental study, the effectiveness of base isolation bearings was discussed for the seismic retrofit of the highway bridges. Four real scale RC pier specimens were constructed for the test. These RC piers didn't have seismic details. Except for one RC pier for the pilot test, three types of bearings such as Pot bearing, Rubber bearing (RB), Lead-rubber bearing (LRB) were applied to the other RC piers respectively. The RC pier with Pot bearing means current state of the prototype bridge that is not retrofitted seismically. And two RC piers with RB or LRB mean assumed states of the prototype bridge that are retrofitted seismically. To simulate dynamic behavior of these RC piers under earthquake loads, Pseudo-dynamic test method was used.

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산업체 급식의 1인 적정섭취량 (A Study on the Development of Properly Portioned Meal Sizes in the Industry Foodservice)

  • 조희숙
    • 한국식품영양학회지
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    • 제12권1호
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    • pp.26-32
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    • 1999
  • The purpose of this study is to set up a appropriate portion by consumed size of food in industry food-service operation. The results were summarized as follows: 51.7% of the subjects were 30 to 39 years old 83.3% of them had highschool education. They represented that taste of food intake. Individual consumption sizes for physical workers in the industry foodservice were cooked rices 238g soups 212g pot stewes 230g stir fries 40g stewes 60g fresh and boiled salad 42g kimchies 51g one course dishies 406g grills 51g meunieres 47g. Properly portioned meal sizes for physical workers based on a statistical data showed cooked rices 240∼270g soups 270g pot stewes 310g stir fries 60g stewes 75g fresh and boiled salads 76g kimchies 67g one course dishies 470g grills 80g and meunieres 50g in the foodservice industry.

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Ring Closure of N-(2-Hydroxyethyl)-N'-phenylthioureas:One-Pot Synthesis of 2-Phenylaminothiazolines

  • 김택현;민정기;이규재
    • Bulletin of the Korean Chemical Society
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    • 제21권9호
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    • pp.919-922
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    • 2000
  • The cyclization reaction of N-(2-hydroxyethyl)-N'-phenylthioureas 2 containingambident nucleophile was ex-amined in the combination of a variety ofbases and p-toluenesulfonyl chloride (TsCl).N-(2-Hydroxyeth-yl) thioureas 2 were readily obtained in high yields from the reaction of the corresponding 1,2-aminoalcohols with phenyl isothiocyanate, avoiding the need for O-protection.The use of a one-pot reaction (NaOH/TsCl) was found to be most effective in producing the requisite 2-phenylaminothiazolines (S-cyclization) 3 in the case ofthioureas 2a-2e derived from N-unsubstituted aminoalcohols,while in the thioureas 2f and 2g prepared from N-substituted aminoalcohols the combination of Et3N and TsCl led to the S-cyclization products.

Synthesis of 2-Oxo-4-quinolines Using One-pot Reaction for Novel Flavonoid Derivatives

  • Park, Myung-Sook;Kim, Nan-Young;Park, Hae-Sun;Kim, Ju-Hee;Lee, Jae-in
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.183.2-183.2
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    • 2003
  • We report the synthesis of 3,4-dihydro-2-oxo-4-quinolines 5a-e for the development novel flavonoid derivatives with potential antiinflammatory activity and propose a mechanism of the one-pot reaction. The various amines (la-e) for this work were commercially available. We isolated that ester (2a-e) were formed by nucleophilic attraction using ethyl benzoylacetate. The C-N bond formation proceeded at refluxing in toluene with catalytic amount of p-toluenesulfonic acid and a removal of water and ethanol was important in this reaction. (omitted)

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One-Pot Electrochemical Synthesis of Hierarchical Porous Niobium

  • Joe, Gihwan;Shin, Heon-Cheol
    • Journal of Electrochemical Science and Technology
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    • 제12권2호
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    • pp.257-265
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    • 2021
  • In this study, we report niobium (Nb) with hierarchical porous structure produced by a one-pot, HF-free electrochemical etching process. It is proved experimentally that a well-defined hierarchical porous structure is produced from the combination of a limited repetition of pulse etching and high concentration of aggressive anion (i.e., SO42-), which results in hierarchical pores with high order over 3. A formula is derived for the surface area of porous Nb as a function of the hierarchical order of pores while the experimental surface area is estimated on the basis of the electrochemical gas evolution rate on porous Nb. From the comparison of the theoretical and experimental surface areas, an in-depth understanding was gained about porous structure produced in this work in terms of the actual pore shape and hierarchical pore order.

정병 받침그릇(淨甁 承盤) 살핌 -고려불화(佛畵)-수월관음그림(水月觀音圖)으로 - (A Study on the "Holing-Bowl(받침그릇, 承盤) for the Jung-Byoung(정병, 淨甁)" or The Sacred Water-pot)

  • 강순형
    • 헤리티지:역사와 과학
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    • 제34권
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    • pp.124-136
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    • 2001
  • Among many different types of wares, we have amazing Sacred Water-pot(따르개, 注子) from Goryo-period(고리, 高麗, 918-1392). The stylistic peculiarity of Jung-Byoung(정병, 淨甁) is described in "Goryo-Dhogyoung, 고리도경, 高麗圖經", the classical design canon. It is said, "A sharpened mouth with narrow and prolonged neck is attached upon the broad mouth with thicker and even longer neck of the pot whose body intimates to the shape of melon." One could find this Jung-Byoung similar to the Indian drinking water jar, Kundika, which has been. even today, an everyday article in houses as well as in temples. In the early Buddhist cult, the object had been adopted as personal belonging of the Bodhisattvas(보살, 菩薩), especially of the Bodhisattva Avalokitesvara(관세음보살,觀世音菩薩). In short, the purifying character of water is met by the sacred ware to deliver the refreshing Sweet-Water(Holy-Water, 깨맑물, 단물, 단이슬물, 정수, 감로, 감로수, 성수, 淨水, 甘露, 甘露水, 聖水): For the holy purpose of fulfilling the thirst of people, of symbolozing the virtuous dharma. Thus, Ggamslkh-Byoung(깨맑병,淨水), the literal Korean name, denotes purifying and clarifying and clarifying water-pot to us. Among many other Asian countries, India, China, Korea, and Japan have a profound cult of the sacred water-pot(Ggamalkh-Byoung, Jung-Byoung, 깨맑병, 정병, 정수병, 감로병, 감로수병, 淨甁, 淨水甁, 甘露甁, 甘露水甁). Therefore, this charming holy object drew much attention not only from master artisans to shape and deliver them to people but also from painters and sculptors for their endowment of the sacred images dedicated to Buddha(부처,佛,佛陀). In China, the sacred water pot emerged in the period of Tang(당, 唐, 618~907)-Period and underwent much sophistication later on, I. e., from earthenware, ceramic-porcelain, bronze, and silver. However, the following represents a challenge to the well-known Goryo-Thangka(고리불화, 高麗佛畵) Painting of Bodhisattva Avalokitesvara to our speculation on the Sacred Water-pot(정병, 淨甁). The image suggests, when examined closely, that the Sacred Water-pot has been accompanied by, or placed in, a transparent glasswere(유리그릇) or crystalbowl(수정그릇)! We have no other physical proof of the existence of such a Holding-Bowl(받침그릇, 承盤), except for in this particular painting. This Holding-Bowl would have not been a mere elaboration on the practicality of controling the drips from the mouth of the pot. As in the chapter on Tang-ho(탕호, 湯壺), or thermal bowl, in the "Goryo-Dhogyoung" it advises readers that this style of bowl is to be filled with hot water, and thus function as a preserver of heat in the water inside the pot. As an offering to the Buddha, the Sacred Water-pot could have been used for serving him hot tea. Hence the sacred bottle is to contain the refreshing water, the water transcends to nectar, and the nectar is prepared as a nectar tea to offer the Buddha. For both the Holding-Bowl of Ggamalkh-Byoung(Jung-Byoung)and the Celestial-Robe(날개옷, 天衣) of the Bodhisattva Avalokitesvara, whose specified character is the Water-Moon(수월, 水月) in this particular Thangka(불화, 佛畵) painting, the transparency is essential. This is to refer to the purity and the lucid clarity of Bodhisattva Avalokitesvara and at a deeper level, to refer to the world of Buddhas-the Tushita(Paradise, Heaven, Eden, 극락, 불세계, 極樂, 佛世界). Howerver, without the discovery of an actual Holding-Bowl, accompanied by a Sacred Water-pot, such speculation will necessarily remain hypothetical. Nevertheless, there is an abundance of evidence of our ancient craftsmanship in jade and ctystal, dating back to the Bronze Age(1000~2B.C.) in Korea. By the time of the Three Kingdom-Period(삼국시대, 三國時代, 57B.C.~935A.D.), and especially the Silla(신라, 新羅, 57B.C.~935A.D.)-Empire, the jade and crystal ornamentation had become very intricate indeed. By the Goryo-Period(918~1392) and Chosun-Period(조선, 朝鮮,1392~1910),crystal-ware and jade art were popular in houses and Buddhist temples, whose master artsanship was heightened in the numerous Sarira-Cases(사리그릇, 舍利器), containing relics and placed inside Stupas(탑, 투, 搭)! Therefore, discovering a tiny part of the crystal or jade Holding-Bowl for the Sacred Water-pot and casting full light on this subject, would not be totally impossible. Lastly the present article shares the tiny hope for a sudden emergence of such a Holding-Bowl.