• Title/Summary/Keyword: OASIS-3

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A Study on Improving the OASIS Selection Guidelines (OASIS의 선정지침 개선(안)에 관한 연구)

  • Noh, Young-Hee;Go, Young-Sun
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.23 no.3
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    • pp.105-137
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    • 2012
  • The historical, social, and cultural value of Internet resources is indisputable, therefore many national institutions have created Web archiving projects to hand down this heritage to future generations. The selection guidelines are the most crucial aspect of these projects because they aid in differentiating which resources are worth collecting and preserving from the large number of web resources available. The purpose of this study was to suggest improvements for the OASIS Selection Guidelines by analyzing the selection guidelines of other domestic and international Web archiving projects. First, based on the results of Web archiving projects abroad, we proposed improvements for the definition of Web data and other terms, the basic principles of the collection, collection methods, and collection cycle. Second, we proposed substantial improvements in the target resources for archiving, and also stated what kind of web resources must be excluded from Web archiving. Finally, we discussed the relationship between data collection methods and the legal deposit of online resources, the necessity of constructing a database for selected target materials, and the necessity of cooperative archiving policies.

Tunicamycin negatively regulates BMP2-induced osteoblast differentiation through CREBH expression in MC3T3E1 cells

  • Jang, Won-Gu;Kim, Eun-Jung;Koh, Jeong-Tae
    • BMB Reports
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    • v.44 no.11
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    • pp.735-740
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    • 2011
  • Tunicamycin, an endoplasmic reticulum (ER) stress inducer, specifically inhibits N-glycosylation. The cyclic AMP (cAMP) response element-binding protein H (CREBH) was previously shown to be regulated by UPR-dependent proteolytic cleavage in the liver. On the other hand, the role of CREBH in other tissues is unknown. In the present study, tunicamycin increased the level of CREBH activation (cleavage) as well as mRNA expression in osteoblast cells. Adenoviral (Ad) overexpression of CREBH suppressed BMP2-induced expression of alkaline phosphatase (ALP) and osteocalcin (OC). Interestingly, the BMP2-induced OASIS (structurally similar to CREBH, a positive regulator of osteoblast differentiation) expression was also inhibited by CREBH overexpression. In addition, inhibition of CREBH expression using siRNA reversed the tunicamycin-suppressed ALP and OC expression. These results suggest that CREBH inhibited osteoblast differentiation via suppressing BMP2-induced ALP, OC and OASIS expression in mouse calvarial derived osteoblasts.

Korean Medicinal Review of the Latest Research Trend on Pathology of Meniere's Disease (메니에르 병의 병리기전에 대한 최신 연구 동향과 한의학적 고찰)

  • Jung, Hye-Jin;Ko, Woo-Shin;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.30 no.3
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    • pp.103-118
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    • 2017
  • Objectives : The purpose of this study is to analyze recent research trend on pathology of Meniere's Disease and review the results in Korean Medicine. Methods : We searched MEDLINE on the title "Meniere's Disease" and "pathology" in recent 5 years and searched OASIS with KISS on the title "Meniere's Disease". Results : We found 21 studies on MEDLINE, 9 studies on OASIS and KISS about Meniere's Disease. The results are as follow. 1. In western medicine, the pathology of Meniere's disease is supposed to be related with endolymphatic hydrops and autoimmunity. The causes of endolymphatic hydrops are studied in various viewpoints such as disorder of endolymph drainage and homeostasis abnormality of endolymph. And autoimmunity is assumed to be associated with genetic factor. 2. In Korean medicine, Meniere's disease were mainly treated with acupuncture and hebal medicine. Conclusions : Korean medicinal approaches on pathology of Meneire's disease can be significant in view of endolymphatic hydrops. And on the basis of those outcomes, much more studies have to be researched for Korean medicinal treatment of Meneire's disease.

Alternative Sample Preparation Techniques in Gas Chromatographic-Mass Spectrometric Analysis of Urinary Androgenic Steroids

  • Cho, Young-Dae;Choi, Man-Ho
    • Bulletin of the Korean Chemical Society
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    • v.27 no.9
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    • pp.1315-1322
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    • 2006
  • The following study describes the gas chromatography-mass spectrometry (GC-MS) based screening and confirmation analysis of urinary androgenic steroids. Four commercially available solid-phase extraction (SPE) cartridges, Serdolit PAD-1, Sep-pak $C_{18}$, amino-propyl, and Oasis HLB, and three different extractive organic solvents, diethyl ether, methyl tert-butyl ether (MTBE), and n-pentane, were tested for sample preparation. Overall, Oasis HLB combined with MTBE extraction provided the highest recoveries in 39 of 46 total androgenic steroids examined and it showed a good extraction yield (>82.1%) for polar steroids, such as metabolites of fluoxymesterone, oxandrolone, and stanozolol, which gave a poor recovery in both n-pentane (9.2-64.3%) and diethyl ether (22.2-73.6%) extractions. All SPE sorbents tested showed potential, because they were efficient in extraction for most or selective steroids. When applied to positive urine samples based on the results obtained, the present method allowed selective and sensitive analysis for detection of urinary androgenic steroids. The experiments showed that the high-resolution MS method is clearly more efficient than the low-resolution MS technique for the detection of many urinary steroids. However, comprehensive sample clean-up procedures also might be needed especially in confirmation analysis to increase detectability.

Determination of phenol using solid-phase extraction and HPLC/MSD/FLD in water (고체상추출법과 HPLC/MSD/FLD를 이용한 수질중의 페놀 분석)

  • Lee, Taejoon;Park, Keun-Young;Pyo, Dongjin
    • Analytical Science and Technology
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    • v.28 no.6
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    • pp.370-376
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    • 2015
  • An analytical method for determining phenol considered priority pollutants of the US EPA and precursor of toxic phenolic compounds by solid-phase extraction (SPE) and high performance liquid chromatographic systems (HPLC) equipped with fluorescence and mass selective detectors have been developed. The SPE process for sample preconcentration was performed on a commercially available Oasis HLB cartridge packed with polymeric sorbents. The effect of pH, elution solvent, and elution volume on the recoveries of the analytes were investigated with HPLC/FLD. Average recovery of >87.0% was achieved with 60 mg sorbents using 5 mL of methanol as an elution solvent at pH=3.

Trend Review of Research about Herbal Medicine Treatment on Colorectal Cancer. - Based on Korean Medicine (대장암에 대한 본초 및 처방의 국내 최신 연구 경향 분석)

  • Cha, Jong-Yeol;Kim, Won-Ill
    • Herbal Formula Science
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    • v.27 no.2
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    • pp.151-165
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    • 2019
  • Objectives : To analyze the latest study trend on effect of herbal medicine treatment for Colorectal Cancer in South Korea. Methods : The theses about colorectal cancer(from 1th January 2000 to 6th August 2016) were searched from National Assembly Library, KIOM OASIS, and National Digital Science Library. Results : 54 theses were analyzed from 87 studies. They were classified by the type of research; experimental theses and case report. The number of experimental theses is 48 and case report is 6. And, they were classified by the topic of research; Single herb, Herbal decoction, oriental foods and Pharmacopuncture, the number of theses about single herb is 29, herbal decoction is 14, oriental foods is 8 and Pharmacopuncture is 3. Rhus Verniciflua(乾漆), Beakduong-tang(白頭翁湯), Wild Ginseng Pharmacopuncture is the most commonly used herb in our research. Conclusion : There were many attempts to develop the way to cure colorectal cancer using korean herbs, and some meaningful results were reported. However, more clinical researches based on human body and more scientifically designed clinical studies are required to prove the effect on colorectal cancer.

준실시간 고정밀 GPS 자료처리 자동화 시스템 구축

  • 하지현;박관동;박필호;임형철
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2003.10a
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    • pp.33-38
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    • 2003
  • We automated high-accuracy data processing routines for various near-real-time GPS applications. The automated system was based on UNIX, and it uses GIPSY-OASIS II and ultra-rapid orbits which is updated twice a day and provided online. The highest error in the estimated site position was 2 cm and 5 cm in the horizontal and vertical directions, respectively. The mean 3-D position error about 2 cm.

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웹 서비스 보안기술 표준화 동향

  • 홍기융;홍기완;박종운;이규호
    • Review of KIISC
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    • v.14 no.4
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    • pp.19-26
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    • 2004
  • 웹 서비스는 인터넷 기술을 이용한 표준화된 오픈 네트워크를 통해 조직 내 및 조직간 모든 컴퓨터 시스템을 결합시키는 새로운 컴퓨팅 패러다임으로 자리 잡으면서, 기술과 서비스의 융합(Convergence), 표준화(Standardization)가 급속도로 진행되고 있다. 이러한 현상은 정보 및 서비스의 공유를 필수적으로 수반하므로, 프라이버시, 기밀성, 무결성, 인증, 및 접근제어 등과 같은 보안과 신뢰성에 대한 중요성을 부각시킨다. 현재 웹 서비스 보안기술은 W3C, OASIS, WS-I의 세 표준화 단체를 중심으로 표준화가 진행되고 있다. 본 논문에서는 각 표준화 단체에서 추진하고 있는 웹서비스 보안기술의 최근 동향을 분석한다.

The Study of the Diarrhea in Sasang Constitutional Medicine (사상의학에서의 설사에 관한 고찰)

  • Song, Eun-Young;Chai, Kwang-Min;Lee, Jun-Hee;Lee, Eui-Ju;Koh, Byung-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.25 no.4
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    • pp.277-288
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    • 2013
  • Objectives This study was aimed to propose the guideline of the diarrhea in Sasang Constitutional Medicine. Methods 1) Literature search It was investigated that the prescriptions stated the diarrhea as a main and accessory symptoms to be treated in "Donguisasangshinpyun", "Donguisusebowon Sasang Chobongwon", "Donguisusebowon Gabobon", "Donguisusebowon Sinchukbon", "Dongmuyugo" 2) Clinial paper search (1) The foreign papers were searched by using the search word with 'Sasang AND Diarrhea' in pubmed (http://www.ncbi.nlm.nih.gov/pubmed/) and The Cochrane Library(http://www.thecochranelibrary.com) (2) The domestic papers were searched by using the search word with 'Soeumin AND Diarrhea', 'Soyangin AND Diarrhea', 'Taeeumin AND Diarrhea', 'Taeyangin AND Diarrhea', 'Sasang AND Diarrhea' in NDSL (http://www.ndsl.kr), KISS(http://kiss.kstudy.com), Oasis(http://oasis.kiom.re.kr), RISS(http://www.riss.kr) (3) The extracted factors were the evaluations on the mainly complained symptom, adopted four constitutional therapy and efficacy. Results & Conclusions The guidelines for treating the diarrhea in the Four Constitutional Medicine are as follows. 1) It is to categorize the constitution. 2) The diarrhea of taeeumin is prescribed with 'A Series of Taeeumjowi-tang, Galgeunhaegi-tang, Cheongsimyeonja-tang, Sahyang-san, etc'. by classifying into cold, fever, consumption and addiction. 3) The diarrhea of soyangin is regarded as an internal disease and it is prescribed with 'Baekhaobuja-tang, Baekhaobujaijung-tang, etc'. by classifying taeeum symptom and so-yin symptom. 4) The diarrhea of soeumin is Mangeum-disease and 'Jeoryeongchajeonja-tang, Hyeongbangsabaek-san, Hwalseokgosam-tang, Hyeongbanggihwang-tang, etc'. is prescribed depending on the complication.

A Quality Assessment of Systematic Review of Oriental Medicine in South Korea (AMSTAR를 활용한 국내 한의학 관련 체계적 문헌고찰 논문의 질 평가)

  • Kim, Yun-Young;Hyun, Hye Sun
    • Journal of Digital Convergence
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    • v.13 no.10
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    • pp.549-559
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    • 2015
  • This study aimed to find the problems of evidence-based complementary and alternative medicine and seek the future development direction by evaluating the quality of oriental medicine related systematic review(SR) studies using AMSTAR tool. The 26 SR studies related to oriental medicine were searched from the database of DBPIA, OASIS, and KISS, and they were evaluated on the basis of AMSTAR. The average of AMSTAR for the quality assessment of SR studies was 6.0 point, and the 26 studies included 2 high quality studies (7.7 %), 21 normal quality studies (80.8 %), and 3 low quality studies (11.5 %). The quality of studies was not correlated with the publication years. The quality of oriental medicine related SR studies need to be improved steadily. Furthermore, continued efforts to promote the evidence-based practice in the field of Oriental Medicine will help to establish foundation for the convergence approach in the healthcare sector.