• Journal of Microbiology and Biotechnology
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• v.34 no.3
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• pp.487-494
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• 2024

Recently, the term metabiotics has emerged as a new concept of probiotics. This concept entails combining existing probiotic components with metabolic by-products improve specific physiological functionalities. Representative ingredients of these metabiotics include short-chain fatty acids (SCFAs), bacteriocins, polysaccharides, and peptides. The new concept is highly regarded as it complements the side effects of existing probiotics and is safe and easy to administer. Known health functions of metabiotics are mainly immune regulation, anti-inflammatory, anticancer, and brain-neurological health. Research has been actively conducted on the health benefits related to the composition of intestinal microorganisms. Among them, the focus has been on brain neurological health, which requires extensive research. This study showed that neurological disorders, such as depression, anxiety, autism spectrum disorder, Alzheimer's disease, and Parkinson's disease, can be treated and prevented according to the gut-brain axis theory by changing the intestinal microflora. In addition, various studies are being conducted on the immunomodulatory and anticancer effects of substances related to metabiotics of the microbiome. In particular, its efficacy is expected to be confirmed through human studies on various cancers. Therefore, developing various health functional effects of the next-generation probiotics such as metabiotics to prevent or treatment of various diseases is anticipated.

• Journal of the military operations research society of Korea
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• v.34 no.3
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• pp.31-40
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• 2008

The aircraft manufacturing industry is a profitable business and has the potential to be an important export business. Our trade deficit needs to be improved in aircraft manufacturing part. Our national aircraft industry, which has been recognized for its quality in many domestic and international Air Shows, has developed the T/A-50 aircraft from the origins of the KT-1. With the ongoing development of the next generation fighter planes and helicopters, business for the next generation domestic air cargo has bright prospects. Judging by the history of the overseas air force dispatch during the Vietnam, Gulf, and Iraqi wars whose main mission was air transportation, there will be many opportunities to show the excellence of Korean air cargo in the future. The purpose of this study is to discover the optimal scale of air cargo development using the AHP method. The authors evaluated the scale of air cargo in size and capacity based on the following 5 standards used Korean developing airliner: usability, economics, technology, safety, and environmental friendliness. Then, the authors modified specific standards suitable for air cargo based on literature review Decision-making groups were chosen for suitability of expert staff in charge because they could represent for leading opinions in this specialized area especially as in practical aspects. The participants of the evaluation were pilots, transportation officers and management staff in the KAI who have experienced over 5years.

• Journal of The Korean Association For Science Education
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• v.36 no.1
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• pp.29-43
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• 2016

There have been much efforts to reconstruct the science curriculum focusing on Disciplinary Core Ideas(DCI) in many countries such as America and Europe, the most practical effort has been to design a curriculum with learning progressions(LPs). LPs describe stepwise how students can systematically move toward the understanding of more sophisticated ideas or scientific activities and explain in succession the process of understanding the ideas while the students learn. In this study, a LP for ecosystems has been developed, and the developed LP is then evaluated accordingly. The Ecosystem is one of the DCI of the life science in Next Generation Science Standards(NGSS). The development process of the LP was set at step 4(Development, Assessment, Analysis, and Amendment), and developed through an iterative process of sequences. As a result of analyzing the developed LP, an assessment based on the LP provides reliable information to identifying student ability. This study proposes the development process of the LP and its methodological aspects to use Core Achievement Standards, Ordered Multiple-Choice items and the Rasch model. In addition, using the empirically proven LP suggests a way of strengthening curriculum linked to educational content, teaching methods and assessment. Utilizing the proposed development process in this study will be to present the standard into the direction of becoming part of the curriculum. Currently, the state of domestic research for the LP is still lacking. This study determined the development process of the LP and the need to conduct future research on the LPs.

• Journal of the Korean Society for Railway
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• v.16 no.1
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• pp.32-39
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• 2013

The next generation high-speed train(HEMU-430X) is Korea's first electric multiple unit type, high speed vehicle resulting from a national R&D project. Tests have been conducted on the Kyungbu High Speed Line running at speeds up to 354.64km/h, and analysis of the dynamic behavior of the train was carried out to evaluate its safety. In this study, a simplified method using an accelerometer(the method specified in UIC 518 OR) was chosen to analyze the safety of the train's dynamic behavior. The section chosen for analysis section was ${\pm}10{\sim}20km/h$ with respect to the maximum speed point. In addition, we analyzed the trend of this dynamic behavior with increasing speed by comparing the analyzed values with those of UIC 518 OR. The dynamic behavior results met the limit values of UIC 518 OR and the study indicates that this trend is predicted to continue at speeds above 354km/h.

• Journal of Life Science
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• v.28 no.1
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• pp.130-139
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• 2018

In ancient times, horse racing was done in ancient European countries in the form of wagon races or mountain races, and wagon racing was adopted as a regular event at the Greek Olympic Games. Thoroughbred horse has been bred since 17th century by intensive selective breeding for its speed, stamina, and racing ability. Then, in the 18th century, horse racing using the Thoroughbred species began to gain popularity among nobles. Since then, horse racing has developed into various forms in various countries and have developed into flat racing, steeplechasing, and harness racing. Thoroughbred racehorse has excellent racing abilities because of powerful selection breeding strategy for 300 years. It is necessary to maintain and maximize horses' ability to race, because horse industries produce enormous economic benefits through breeding, training, and horse racing. Next-generation sequencing (NGS) methods which process large amounts of genomic data have been developed recently. Based on the remarkable development of these genomic analytical techniques, it is now possible to easily carry out animal breeding strategies with superior traits. In order to select breeding racehorse with superior racing traits, the latest genomic analysis techniques have to be introduced. In this paper, we will review the current efforts to improve race performance for racehorses and to examine the research trends of genomic analysis. Finally, we suggest to utilize genomic analysis in Thoroughbred racehorse and Jeju horse, and propose a strategy for selective breeding for Jeju horse, which contributes job creation of Korea.

• Journal of Digital Contents Society
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• v.12 no.1
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• pp.85-94
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• 2011

QoS(Quality of Service) is defined as "The collective effect of service performance which determines the degree of satisfaction of a user of the service" by ITU-T Rec. E.800. While the use of VoIP(Voice Over Internet Protocol) has been widely implemented, persistent problems with QoS are a very important sue which needs to be solved. This research is finding the assignment of VoIP QoS to deduct how to manage the control system and presenting the QoS control process and framework under NGN(Next Generation Network) environment. The trial framework is the modeling of the QoS measurement metrics, instrument, equipment, method of measurement, the series of cycle & the methodology about analysis of the result of measurement. This research underlines that the vulnerability of the VoIP protocol in relation to its QoS can be guaranteed when the product quality and management are controlled and measured systematically. Especially it's very important time to maintain the research about VoIP QoS measurement and control because the big conversion of new network technology paradigm is now spreading. In addition, when the proposed method is applied, it can reduce an overall delay and can contribute to improved service quality, in relation to signal, voice processing, filtering more effectively.

• Journal of Life Science
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• v.28 no.10
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• pp.1244-1253
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• 2018

Rumen microbiome consists of a wide variety of microorganisms, such as bacteria, archaea, protozoa, fungi, and viruses, that are in a symbiotic relationship in a strict anaerobic environment in the rumen. These rumen microbiome, a vital maker, play a significant role in feed fermentation within the rumen and produce different volatile fatty acids (VFAs). VFAs are essential for energy metabolism and protein synthesis of the host animal, even though emission of methane gas after feed fermentation is considered a negative indicator of loss of dietary energy of the host animal. To improve rumen microbial efficiency, a variety of approaches, such as feed formulation, the addition of natural feed additives, dietary feed-microbes, etc., have taken to increase ruminant performance. Recently with the application of high-throughput sequencing or next-generation sequencing technologies, especially for metagenomics and metatranscriptomics of rumen microbiomes, our understanding of rumen microbial diversity and function has significantly increased. The metaproteome and metabolome provide deeper insights into the complicated microbial network of the rumen ecosystem and its response to different ruminant diets to improve efficiency in animal production. This review summarized some recent advances of rumen microbiome techniques, especially "meta-omics," viz. metagenomic, metatranscriptomic, metaproteomic, and metabolomic techniques to increase feed fermentation and utilization in ruminants.

• Journal of the Korean Geographical Society
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• v.46 no.2
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• pp.168-180
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• 2011

The accuracy of rainfall data for a hydrological modeling study is important. NEXRAD (Next Generation Radar) rainfall data estimated by WRS-88D (Weather Surveillance Radar - 1988 Doppler) radar system has advantages of its finer spatial and temporal resolution. In this study, NEXRAD rainfall data was tested and compared with conventional weather station data using the previously calibrated SWAT (Soil and Water Assessment Tool) model to identify local storms and to analyze the impacts on hydrology. The previous study used NEXRAD data from the year of 2000 and the NEXRAD data was substituted with weather station data in the model simulation in this study. In a selected watershed and a selected year (2006), rainfall data between two datasets showed discrepancies mainly due to the distance between weather station and study area. The largest difference between two datasets was 94.5 mm (NEXRAD was larger) and 71.6 mm (weather station was larger) respectively. The differences indicate that either recorded rainfalls were occurred mostly out of the study area or local storms only in the study area. The flow output from the study area was also compared with observed data, and modeled flow agreed much better when the simulation used NEXRAD data.

• Korean Journal of Environment and Ecology
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• v.35 no.5
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• pp.503-524
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• 2021

A largemouth bass (Micropterus salmoides) is an ecosystem disturbance fish species at the highest rank in the aquatic ecosystem, causing a serious imbalance in freshwater ecosystems. Although various attempts have been made to eradicate and control largemouth bass, no effective measures were found. Therefore, it is necessary to find an approach to maximize the effective population reduction based on the unique characteristics of largemouth bass. This study used the transcriptome analysis to derive 182,887 unigene contigs and select 12 types of final target sequences for applying the CRISPR/Cas9 system in the genes of IZUMO1 and Zona pellucida sperm-binding protein, which are proteins involved in sperm-egg recognition. After synthesizing 12 types of sgRNA capable of recognizing each target sequence, 12 types of Cas9-sgRNA ribonucleoprotein (RNP) complexes to be used in subsequent studies were prepared. This study searched the protein-coding gene of sperm-egg through the Next Generation Sequencing (NGS) and edited genes through the CRISPR/Cas9 system to induce infertile individuals that produced reproductive cells but could not form fertilized eggs. Through such a series of processes, it successfully established a composition development process for largemouth bass. It is judged that this study contributed to securing the valuable basic data for follow-up studies to verify its effect for the management of ecological disturbances without affecting the habitat of other endemic species in the same water system with the largemouth bass.

• The Journal of Korean Institute of Next Generation Computing
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• v.14 no.6
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• pp.44-56
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• 2018

Researches on military weapons are actively studied to improve national defense power of each country. The military weapon system is being used not only as a weapon but also as a reconnaissance and surveillance device for places where it is difficult for people to access. If such a weapon system becomes an object of attack, military data that is important to national security can be leaked. Furthermore, if a device is taken, it can be used as a terrorist tool to threaten its own country. So, security of military devices is necessarily required. In order to enhance the security of a weapon system such as drone, it is necessary to form a chain of trust(CoT) that gives trustworthiness to the overall process of the system from the power on until application is executed. In this paper, by analyzing the trusted computing-based boot technology, we derive trusted boot technology components and classify them based on hardware dependence/independence. We expect our classification of hardware dependence/independence to be applied to the trusted boot technology of our self-development ultraprecision weapon system to improve the defense capability in our military.