• Proceedings of the Korean Reliability Society Conference
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• 2001.06a
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• pp.311-319
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• 2001

All indices that are now in use assume normally distributed data, and any use of the indices on non-normal data results in inaccurate capability measurements. Therefore, $C_{s}$ is proposed which extends the most useful index to date, the Pearn-Kotz-Johnson $C_{pmk}$, by not only taking into account that the process mean may not lie midway between the specification limits and incorporating a penalty when the mean deviates from its target, but also incorporating a penalty for skewness. Therefore we propose, a new process capability index $C_{psk}$( WV) applying the weighted variance control charting method for non-normally distributed. The main idea of the weighted variance method(WVM) is to divide a skewed or asymmetric distribution into two normal distribution from its mean to create two new distributions which have the same mean but different standard distributions. In this paper we propose an example, a distribution generated from the Johnson family of distributions, to demonstrate how the weighted variance-based process capability indices perform in comparison with another two non-normal methods, namely the Clements and the Wright methods. This example shows that the weighted valiance-based indices are more consistent than the other two methods In terms of sensitivity to departure to the process mean/median from the target value for non-normal process.s.s.s.

• Journal of Korean Society for Quality Management
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• v.30 no.3
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• pp.66-78
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• 2002

Process capability indices are being used as indicators for measurements of process capability for SPC of quality assurance system in industries. In view of the enhancement of customer satisfaction, process capability indices in which loss functions are used to deal with the economic loss In the processes deviated from the target, are in an adequate representation of the customer's perception of quality In this connection, the loss function has become increasingly important in quality assurance. Taguchi uses a modified form of the quadratic loss function to demonstrate the need to consider the proximity to the target while assessing its quality. But this traditional quadratic loss function is inadequate to assessing the quality and quality improvement since different processes have different sets of economic consequences on the manufacturing, Thereby, a flexible approach to the development of the loss function needs to be desired. In this paper, we introduce an easily understood loss function, based on reflection of probability density function of the normal distribution. That is, the Reflected Normal Loss function can be adapted to an asymmetric loss as well as to a symmetric loss around the target. We propose that, instead of the process variation, a new capability index, CpI using the Reflected Normal Loss Function that can accurately reflect the losses associated with the process and a new capability index CpI Is compared with the classical indices as $C_{p}$ , $C_{pk}$, $C_{pm}$ and $C_{pm}$ $^{+}$.>.+/./.

• Journal of Korean Academy of Nursing
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• v.37 no.1
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• pp.91-104
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• 2007

Purpose: The purpose of this study was to explore the experiences of parenting from the parents of children with ADHD and to develop a grounded theory about their experiences. Method: This study was a qualitative research study that used a grounded theory to understand and discuss the parenting experiences of parents of children with ADHD in a greater depth. Grounded data was collected through an in-depth interview from twelve participants with ADHD children. The data was analyzed using the grounded theory method. Results: 'Approaching the normal' emerged as the core phenomenone. Parenting experiences for parents of children with ADHD referred to a process of bringing the children, back on track of normal growth development, and their functioning in the family at a normal level and establishing a new normalcy. The process of approaching the normal involved a basic social-psychological process, such as 'living a day in hell', 'accepting', 'confronting the conflicts', 'lowering expectations', and 'making a new normalcy'. Conclusion: The outcomes of this study, which observed the parenting process of parents of children with ADHD, could enhance nurses' understanding of ADHD and help nurses become major mental health service providers for the mental health of children with ADHD and their families.

• Speech Sciences
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• v.10 no.4
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• pp.189-200
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• 2003

The objective of this study was to examine two new parameters by which we could screen people with malignant vocal folds. The new parameters were the difference sums and Pearson correlation coefficients between adjacent pairs of intensity level matrices of narrow-band spectra. Audio files from the Korean Disordered Speech Database were analyzed by Praat, a speech analysis software, to obtain matrices of 400 intensity levels at 16 time points of each sustained vowel spectra. We limited our study to 12 normal subjects and 20 patients with malignant vocal folds who recorded at least three Korean vowels at a sound-proofed booth in Busan National University Hospital. Results indicated that the average coefficients of the abnormal subjects were much lower than those of the normal subjects while the average difference sums of the patients were much higher than those of the normal ones. Also, we found that the degree of the malignancy of the vocal folds was related to the coefficients and sums. However, some subjects at the initial stages of cancerous vocal folds yielded almost comparable coefficients and difference sums to those of the normal speakers. Further studies on larger databases will be desirable to set certain criteria or threshold levels for screening people with vocal fold diseases.

• Journal of Korean Society for Quality Management
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• v.26 no.1
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• pp.48-60
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• 1998

This paper proposes a fourth generation index $C_{psk}$, constructed from $C_{psk}$, by introducing the factor｜$\mu$-T｜ in the numerator as an extra penalty for the departure of the process mean from the preassigned target value T. The motivation behind the introduction of $C_{psk}$ is that when $T\neqM$ process shifts away from target are evaluated without respect to direction. All indices that are now in use assume normally distributed data, and any use of the indices on non-normal data results in inaccurate capability measurements. In this paper, a new process capability index $C_{psk}$ is introduced for non-normal process. The Pearson curve and the Johnson curve are selected for capability index calculation and data modeling the normal-based index $C_{psk}$ is used as the model for non-normal process. A significant result of this research find that the ranking of the six indices, $C_{p}$, $C_{pk}$, $C_{pm}$, ${C^*}_{psk}$, $C_{pmk}$, $C_{psk}$in terms of sensitivity to departure of the process median from the target value from the most sensitive one up to the least sensitive are $C_{psk}$, $C_{pmk}$, ${C^*}_{psk}$,$C_{pm}$, $C_{pk}$, $C_{p}$.

• Journal of Microbiology and Biotechnology
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• v.26 no.4
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• pp.730-738
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• 2016

est19 is a gene from Bacillus sp. K91 that encodes a new esterase. A comparison of the amino acid sequence showed that Est19 has typical Ser-Gly-Asn-His (SGNH) family motifs and could be grouped into the SGNH hydrolase family. The Est19 protein was functionally cloned, and expressed and purified from Escherichia coli BL21(DE3). The enzyme activity was optimal at 60℃ and pH 9.0, and displayed esterase activity towards esters with short-chain acyl esters (C₂-C₆). A structural model of Est19 was constructed using phospholipase A1 from Streptomyces albidoflavus NA297 as a template. The structure showed an α/β-hydrolase fold and indicated the presence of the typical catalytic triad Ser49-Asp227-His230, which were further investigated by site-directed mutagenesis. To the best of our knowledge, Est19 is a new member of the SGNH hydrolase family identified from thermophiles, which may be applicable in the industrial production of semisynthetic β-lactam antibiotics after modification.

• Journal of Microbiology and Biotechnology
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• v.24 no.11
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• pp.1551-1558
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• 2014

The esterase gene Est8 from the thermophilic bacterium Bacillus sp. K91 was cloned and expressed in Escherichia coli. The monomeric enzyme exhibited a theoretical molecular mass of 24.5 kDa and an optimal activity around $50^{\circ}C$ at pH 9.0. A model of Est8 was constructed using a hypothetical YxiM precursor structure (2O14_A) from Bacillus subtilis as template. The structure showed an ${\alpha}/{\beta}$-hydrolase fold and indicated the presence of a typical catalytic triad consisting of Ser-11, Asp-182, and His-185, which were investigated by site-directed replacements coupled with kinetic characterization. Asp-182 and His-185 residues were more critical than the Ser-11 residue in the catalytic activity of Est8. A comparison of the amino acid sequence showed that Est8 could be grouped into the GDSL family and further classified as an SGNH hydrolase. Est8 is a new member of the SGNH hydrolase subfamily and may employ a different catalytic mechanism.

• The Korean Journal of Applied Statistics
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• v.23 no.4
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• pp.759-765
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• 2010

In this paper, two new inverse regression methods are introduced. One is a distance based method, and the other is a likelihood based method. While a model is fitted by minimizing the sum of squared prediction errors of y's and x's in the classical and inverse methods, respectively. In the new distance based method, we simultaneously minimize the sum of both squared prediction errors. In the likelihood based method, we propose an inverse regression with Arnold-Beaver Skew Normal(ABSN) error distribution. Using the cross validation method with an asymmetric real data set, two new and two existing methods are studied based on the relative prediction bias(RBP) criteria.

• Communications of the Korean Mathematical Society
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• v.27 no.3
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• pp.547-556
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• 2012

A new Hardy-Hilbert type integral inequality for double series with weights can be established by introducing a parameter ${\lambda}$ (with ${\lambda}>1-\frac{2}{pq}$) and a weight function of the form $x^{1-\frac{2}{r}}$ (with $r$ > 1). And the constant factors of new inequalities established are proved to be the best possible. In particular, for case $r$ = 2, a new Hilbert type inequality is obtained. As applications, an equivalent form is considered.

• Journal of Advanced Marine Engineering and Technology
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• v.30 no.5
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• pp.589-596
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• 2006

This study aims to propose a new model axial flow fan which attachs centrifugal blades, and to investigate the effect of centrifugal blades on the performance improvement of new model axial flow fan. A numerical simulation has been conducted using STAR-CD commercial code to solve the three dimensional incompressible Navier-Stokes equation for high Reynolds number $k-{\epsilon}$ turbulent model. Numerical simulation is carried out to investigate the detail phenomenon in the flow field and performance characteristics of new model and normal model fan. Calculation results are compared with normal model's results to investigate which centrifugal blades effect on velocity profile and pressure distribution at various flow field positions. and calculation results show that new model fan can improve the performance of total pressure.