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Pseudoreceptor: Concept and an Overview

  • Kothandan, Gugan;Madhavan, Thirumurthy;Gadhe, Changdev G.;Cho, Seung Joo
    • Journal of Integrative Natural Science
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    • v.3 no.3
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    • pp.162-167
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    • 2010
  • A pseudoreceptor combines structure-based and ligand-based techniques to represent a unifying concept for both receptor mapping and ligand matching. In this molecular modeling approach, there are opportunities to construct the pseudoreceptor models using a set of small molecules. To build a reliable pseudoreceptor model, we need a set of ligand molecules with known affinity (biological activity) to generate 3D bioactive conformation for each of these ligand molecules. Several software packages are available to generate a pseudoreceptor model and this can provide an entry point for structure based drug discovery in cases where receptor structure information is not available. In this review, we presented the concept of pseudoreceptor, as well as discussed about various software packages available to generate a pseudoreceptor model.

The Elevator, the Iron Skeleton Frame, and the Early Skyscrapers: Part 2

  • Larson, Gerald R.
    • International Journal of High-Rise Buildings
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    • v.9 no.1
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    • pp.17-41
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    • 2020
  • In Part One, I documented the evolution of the use of the elevator and the iron frame to build ever-taller buildings that would eventually be called "skyscrapers," to offset the ever-increasing cost of Manhattan real estate. By the start of the Great Depression of the 1870s in 1873, New York architects had erected two ten-storied skyscrapers. In Part Two I document the major events, designers, and buildings in New York, Chicago, and other American cities that eventually culminated in the ability to erect 20 story skyscrapers by 1890.

Design of Food Management System Using NFC Tag

  • Lee, Jong-Chan;Bahk, Gyung-Jin
    • Journal of the Korea Society of Computer and Information
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    • v.23 no.5
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    • pp.25-29
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    • 2018
  • As society advances and consumers' perception of food safety changes, the demand for the safety of refrigerated and distributed foods is spreading. In this paper, we build an ICT system that can collect the TTH data from the NFC tag, store it, analyze the food safety level using it. This service platform consists of the temperature monitoring NFC tag attached to individual packaged food, the smartphone with NFC sensor, and the monitoring server with a big data system. Consumers and administrators in this system can easily identify and predict the safety level of individual packaged foods in real time using the provided app on smartphones. In the field of food safety, the use of new technologies such as ICT can create new value by combining with existing food industry in addition to creating new market by new service.

Development of Gun Fire Control System for the FFX-I Program (차기호위함 전투체계용 함포 사격제원계산장치 개발)

  • Suh, Tae-Il;Kim, Eui-Jin
    • Journal of the Korea Institute of Military Science and Technology
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    • v.16 no.6
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    • pp.752-761
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    • 2013
  • A new gun fire control system has been developed for the Korean next generation frigate class. The engineering requirement was far more tightened than the PKG-A class for the firing range availability and gun control function since 5 inch gun is adopted for the new ship. We mention about the principal technologies required to build a generic gun fire control system and proposed methods for the new gun fire control system. The new system has been designed based on the proposed methods in order to satisfy the requirement and functionality has been proved to be acceptable through the sea trial by Korean navy.

CSP + HDI : MCM!

  • Bauer, Charles-E.
    • Proceedings of the International Microelectronics And Packaging Society Conference
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    • 2000.04a
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    • pp.35-40
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    • 2000
  • MCM technology languished troughout most of the 1990's due to high costs resulting from low yields and issues with known god die. During the last five years of the decade new developments in chip scale packages and high density, build up multi-layer printed wiring boards created new opportunities to design and produce ultra miniaturized modules using conventional surface mount manufacturing capabilities. Focus on the miniaturization of substrate based packages such as ball grid arrays (BGAs) resulted in chip scale packages (CSPs) offering many of the benefits of flip chip along with the handling, testing, manufacturing and reliability capabilities of packaged deviced. New developments in the PWB industry sought to reduce the size, weight, thickness and cost of high density interconnect (HDI) substrates. Shrinking geometries of vias and new constructions significantly increased the interconnect density available for MCM-L applications. This paper describes the most promising CSP and HDI technologies for portable products, high performance computing and dense multi-chip modules.

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Organizational Design for New Product Architecture Development: Comparative Analysis of Sharp and Casio on PDA Development (신규 제품아키텍처 개발을 위한 기업조직의 설계: PDA 개발에 있어 샤프와 카시오의 개발조직 비교 분석)

  • Wi John-H.
    • Journal of Technology Innovation
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    • v.14 no.1
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    • pp.1-30
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    • 2006
  • The purpose of this paper is to analyze the organizational design and management of product development in creating new product architecture by an established firm. For the purpose, the paper put up the organizational design in the process of PDA(Personal Digital Assistant) development of Sharp and Casio which were Japanese major PDA firms in 1990s. PDA is the product born through architectural change from Electronic Organizer. Prior research on the product architecture change and organizational adaptation emphasized that an established firm is difficult to adapt to new product architecture due to the restriction of prior technology or organizational inertia. For overcoming these problems and successful development of new product architecture, organizational design and management in the process of product development becomes essential. In case of Sharp, corporate development project team had been used to overcome the restrictions from architectural knowledge accumulated through previous product. After launching first new PDA by corporate development project team, Sharp created a new division and pushed an evolution of PDA, when new PDA market start to grow up rapidly toward a major market segmentation. As a result, Sharp was able to build up stable PDA project trajectory. However, Casio was late for three years in launching of new PDA architecture because previous division charging of Electronic Organizer tried to develop first new PDA. Casio's PDA development was prohibited by engineers of previous division because new PDA architecture was inferior on user interface and display definition. That is, Casio's first PDA development was restricted by architectural knowledge of previous product.

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Research on the Strategy to build the Tourism Brand Image for the Inducement of Foreign Tourist in Chungnam (외국인 관광객 유치를 위한 충남관광 브랜드이미지 구축에 관한 연구)

  • You, Ho-Jong
    • International Commerce and Information Review
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    • v.14 no.2
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    • pp.121-145
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    • 2012
  • This research was performed to review the marketing PR(MPR) strategy to build the brand image of Chungnam tourism for the inducement of foreign tourist. Because each local governments are looking for the industries of new growth power from the tourism industry recently, we applied the BI strategy of Chungnam tourism with expended BLC model and GRID model after we analyzed the variety of PR situation and tasks to build the Chungnam tourism's brand image in the competitive domestic and foreign tourism industry. In the result of the study, we set up the limited brand image of Chungnam tourism newly; also we derived a specific action plan. First of all, they need every possible means for Brand Awareness PR, Issue PR, Brand Loyalty PR, etc. depend on brand life cycle with the Chungnam's tourism service products. Secondly, for the each tourism service products, it is requiring to repositioning from present position (B, C, D area) to A area by MPR strategy. Finally, many additional MPR strategies should put in to support for building the brand image for the 'Tourism Chungnam'. The strategic SNS public relations are required with considerations of items that are necessarily need to have the reasons and circumstances for the new foreign tourists, so they can have experiences for the Chungnam Tourism. For the existing foreign tourists, we should keep to build relationship in order to give them trusts and to feel sympathy.

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신규제품 아키텍처 개발을 위한 기업조직의 설계 -PDA 개발에 있어 샤프와 카시오의 개발조직 비교 분석-

  • Wi, Jeong-Hyeon
    • Proceedings of the Technology Innovation Conference
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    • 2005.06a
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    • pp.44-68
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    • 2005
  • The purpose of this paper is to analyze the organizational design and management of product development in creating new product architecture by an established firm. For the purpose, the paper put up the organizational design in the process of PDA(Personal Digital Assistant) development of Sharp and Casio which were Japanese major PDA firms in 1990s. PDA is the product born through architectural change from Electronic Organizer. Prior research on the product architecture change and organizational adaptation emphasized that an established firm is difficult to adapt to new product architecture due to the restriction of prior technology or organizational inertia. For overcoming these problems and successful development of new product architecture, organizational design and management in the process of product development becomes essential. In case of Sharp, corporate development project team had been used to overcome the restrictions from architectural knowledge accumulated through previous product. After launching first new PDA by corporate development project team, Sharp created a new division and pushed an evolution of PDA, when new PDA market start to grow up rapidly toward a major market segmentation. As a result, Sharp was able to build up stable PDA project trajectory. However, Casio was late for three years in launching of new PDA architecture because previous division charging of Electronic Organizer tried to develop first new PDA. Casio's PDA development was prohibited by engineers of previous division because new PDA architecture was inferior on user interface and display definition. That is, Casio's first PDA development was restricted by architectural knowledge of previous product.

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Revision and Implementation of App Inventor Open Source (앱인벤터 오픈소스 수정·구현)

  • Kim, Byungho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.2
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    • pp.221-226
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    • 2018
  • Open source software allows revising and adding a new idea on them as well as debugging themselves. The open source software can be utilized as various educational programs as well as development of a commercial software products using them. MIT App Inventor, one of the block-based visual programming environments for education, supports building a local server and even revision of the platform itself by providing its own source codes. In this paper we implement App Inventor open sources on the local server. Especially we present how to revise and implement a new App Inventor platform reflecting their own requirements in schools or educational institutes and how to build a local server operating the revised App Inventor platform. They can provide more interactive educational environments to students and improve educational satisfaction through the active customizing of the platform itself such as adding new programming block components requested by students.

Mobile Web Automatic Generation using the Web users usage pattern (사용자 이용패턴을 이용한 모바일웹 컨텐츠 자동 생성에 관한 연구)

  • Ko, Hee-Ae;Kim, Jong-Keun;Sim, Kun-Ho;Meihua, Zhao;Yin, Chang-Yi;Lim, Young-Hwan
    • Journal of Digital Contents Society
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    • v.9 no.4
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    • pp.583-590
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    • 2008
  • These days Mobile web Full Browsing is getting the issues which displays whole Web Site contents in browser of mobile device. Since the size of browser is too small, in this paper, it recommends a new method that web users can choose variable service and web contents for mobile contents by adopting new platform. The mobile web would be generated automatically to apply the web 2.0 through the web users pattern. The platform is that no one belong in data, anyone can use this, anyone can modify the data, so variable users can create new contents for proper mobile web. It is the Mobilder application which can build Mobile web pages. Any User can make mobile web pages with Mobilder Before producing the program, in this paper, it will build mobile web pages by web users navigation pattern. After analysing the web users pattern, we will produce the mobile web pages through this.

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