• International Journal of Automotive Technology
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• v.5 no.1
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• pp.61-67
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• 2004

This paper suggests two simple two-degree-of-freedom models to describe the dynamical interaction between the pad and the disc of a disc brake system. Separate models for in-plane and out -of-plane vibration are described. Although a brake pad and disc have many modes of vibration, the interaction between a single mode of each component is considered as this is thought to be crucial for brake noise. For both models, the pad and the disc are connected by a sliding friction interface having a velocity dependent friction coefficient. In this paper, it is shown that this friction model acts as negative damping in the system that describes the in-plane vibration, and as negative stiffness in system that describes the out-of-plane vibration. Stability analysis is performed to investigate the conditions under which the systems become unstable. The results of the stability analysis show that the damping is the most important parameter for in-plane vibration, whereas the stiffness is the most important parameter for the out-of-plane vibration.

• Biomolecules & Therapeutics
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• v.26 no.2
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• pp.182-190
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• 2018

The objective of this work is to evaluate the effect of polyamidoamine (PAMAM) dendrimers on electroosmotic flow (EOF) through skin. The effect of size and concentration of dendrimer was studied, using generation 1, 4 and 7 dendrimer (G1, G4 and G7, respectively). As a marker molecule for the direction and magnitude of EOF, a neutral molecule, acetoaminophen (AAP) was used. The visualization of dendrimer permeation into the current conducting pore (CCP) of skin was made using G4-fluorescein isothiocyanate (FITC) conjugate and confocal microscopy. Without dendrimer, anodal flux of AAP was much higher than cathodal or passive flux. When G1 dendrimer was added, anodal flux decreased, presumably due to the decrease in EOF by the association of G1 dendrimer with net negative charge in CCP. As the generation increased, larger decrease in anodal flux was observed, and the direction of EOF was reversed. Small amount of methanol used for the preparation of dendrimer solution also contributed to the decrease in anodal flux of AAP. Cross-sectional view perpendicular to the skin surface by confocal laser scanning microscope (CLSM) study showed that G4 dendrimer-FITC conjugate (G4-FITC) can penetrate into the viable epidermis and dermis under anodal current. The permeation route seemed to be localized on hair follicle region. These results suggest that PAMAM dendrimers can permeate into CCP and change the magnitude and direction of EOF. Overall, we obtained a better understanding on the mechanistic insights into the electroosmosis phenomena and its role on flux during iontophoresis.

• Bulletin of the Korean Mathematical Society
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• v.50 no.4
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• pp.1087-1098
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• 2013

We find a $C^{\infty}$-continuous path of Riemannian metrics $g_t$ on $\mathbb{R}^k$, $k{\geq}3$, for $0{\leq}t{\leq}{\varepsilon}$ for some number ${\varepsilon}$ > 0 with the following property: $g_0$ is the Euclidean metric on $\mathbb{R}^k$, the scalar curvatures of $g_t$ are strictly decreasing in $t$ in the open unit ball and $g_t$ is isometric to the Euclidean metric in the complement of the ball. Furthermore we extend the discussion to the Fubini-Study metric in a similar way.

• Bulletin of the Korean Mathematical Society
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• v.49 no.3
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• pp.581-588
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• 2012

We find a $C^{\infty}$ one-parameter family of Riemannian metrics $g_t$ on $\mathbb{R}^3$ for $0{\leq}t{\leq}{\varepsilon}$ for some number ${\varepsilon}$ with the following property: $g_0$ is the Euclidean metric on $\mathbb{R}^3$, the scalar curvatures of $g_t$ are strictly decreasing in t in the open unit ball and $g_t$ is isometric to the Euclidean metric in the complement of the ball.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.2
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• pp.338-343
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• 2001

The ethanol extract of Quercus mongolica leaf was fractionated by various organic solvents, and their antimicrobial and antioxidative activities were investigated against several microorganisms. The ethanol extract of Quercus mongolica leaf at two thousand $\mu\textrm{g}$ per disc showed 17~21mm inhibition zone against Gram postive and Gram negative bacteria. Among the various solvent fractions from ethanol extract of Quercus mongolica leaf, the hexane fraction showed the strongest antimicrobial activity. Minimal inhibitory concentration (MIC) of hexane fraction was 250$\mu\textrm{g}$/mL against Bacillus cereus, 250~500$\mu\textrm{g}$/mL against Listeria monocytogenes, 500$\mu\textrm{g}$/mL against Staphylococcus aureus, Salmonella typhimurium, Escherichia coli O157, and Pseudomonas aeruginosa. Also, the hexane and chloroform fraction had the similar antioxidative activity compared to that of butylated hydroxy toluene(BHT).

• 대한예방의학회:학술대회논문집
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• 1994.02b
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• pp.158-163
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• 1994

Slightly elevated urinary albumin excretion rate (microalhuminuria) is a marker of early diabectic nephropathy, but it is unclear if the established definition of microalbuminuria ($20-200{\mu}g/min$) is correct for children and adolescents. We investigated th.: albumin excretion rate, albumin/creatinine ratio and urinary albumin concentration in 150 healthy schoolchildren and adolescents to (a) obtain a reterence value for albumin excretion rate, (b) relate albumin excretion to pubertal stages and (c) evaluate albumin/creatinine ratio and morning albumin concentration as screening methods for elevated albumin excretion rate. Albumin concentration was measured by immunoturbidimetry in timed overnight urine samples. The albumin excretion showed a skewed distribution (geometric mean $3.2{\mu}g/min$, 95 percentile ($15.1{\mu}g/min$). In girls. a peak in the albumin excretion rate was found at the pubertal stage 4 (Tanner) and in boys at stage 5. Albumin/creatinine ratio of 2.5 mg/mmol as a screening level for elevated albumin excretion ($15{\mu}g/min$) showed a high positive (0.88) and negative (0.99) predictive value.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.5
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• pp.474-480
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• 2008

In order to make full color cholesteric displays, color filter-less R, G, B sub-pixel structured cholesteric LC cells have been studied. To make R, G, B colors, UV induced pitch variant chiral dopant was added to cholesteric LC mixtures. The concentration of the photo-sensitive chiral dopant was adjusted so that the initial state showed blue color and the color was changed from blue to green and red with increase of UV irradiation to the cholesteric cells. To prevent the mixing of R, G, B reflective sub-pixel liquid crystals, separation walls were formed using negative photo resister in boundary area between sub-pixels, Through the optimization of the material concentrations and UV irradiation condition, vivid R, G, B colors were achieved.

• Journal of the Korean Mathematical Society
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• v.56 no.5
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• pp.1371-1385
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• 2019

Given a topological space X and a non-negative integer k, ${\varepsilon}^{\sharp}_k(X)$ is the set of all self-homotopy equivalences of X that do not change maps from X to an t-sphere $S^t$ homotopically by the composition for all $t{\geq}k$. This set is a subgroup of the self-homotopy equivalence group ${\varepsilon}(X)$. We find certain homotopic tools for computations of ${\varepsilon}^{\sharp}_k(X)$. Using these results, we determine ${\varepsilon}^{\sharp}_k(M(G,n))$ for $k{\geq}n$, where M(G, n) is a Moore space type of (G, n) for a finitely generated abelian group G.

• Journal of Information Technology Applications and Management
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• v.26 no.1
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• pp.1-19
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• 2019

The aim of this study is to assess the impacts of service properties, price expectancy, social influences, and switching costs on adoption intention of 4G in Vietnam. The research model was established by the theory of diffusion of innovation, technology acceptance model, service quality, social influences and switching costs. The result from customers using telecommunication services in Vietnam shows that adoption intention of 4G is affected directly by perceived usefulness, personal innovativeness, price expectancy, social influences, prior service quality and switching costs. Whereas, switching costs have negative effect on adoption intention. Other factors such as personal innovativeness, perceived ease of use and prior service quality have an indirect effect on adoption intention of 4G.

• The Journal of Korean Medicine
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• v.41 no.4
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• pp.64-71
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• 2020

Objectives: This study was done to look into whether Nrf2 take some role in the anti-lipogenic effect of kaurenoic acid in a nonalcoholic fatty liver disease (NAFLD) cellular model. Materials and Methods: We measured the effect of kaurenoic acid on intracellular steatosis and Nrf2 activation. Next, the effect of kaurenoic acid on SREBP-1c and some lipogenic genes in palmitate treated HepG2 cells with or without Nrf2 silencing. Results: The increased SREBP-1c expression was significantly decreased by concomitant kaurenoic acid treatment in non-targeting negative control siRNA transfected HepG2 cells. However, kaurenoic acid did not significantly inhibited increased SREBP-1c level in Nrf2 specific siRNA transfected HepG2 cells Conclusions: Kaurenoic acid has a potential to activate Nrf2, which may suppress SREBP-1c mediated intracellular steatosis in HepG2 cells.