• 제목/요약/키워드: Negative Pressure Room

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소아 코로나바이러스감염증-19에서 발생한 열성 경련 (Febrile Seizure Associated With COVID-19 in a Child: Case Report and Literature Review)

  • 조유리;정나영;김민경;권영세;김동현
    • Pediatric Infection and Vaccine
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    • 제31권1호
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    • pp.147-152
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    • 2024
  • 기저 질환 없이 평소 건강하던4세 남아에서 COVID-19와 연관된 열성 경련이 발생하였다. SARS-CoV-2 양성으로 확인되어 음압격리병동에 입원한 당일 발열과 함께 25분간 전신 간대성 발작이 있었고 산소흡입, 항경련제 투여 후 소실되었다. 말초혈액, 혈액화학, 전해질, 혈액기체분석, 급성기반응물질, 면역혈청, 특수화학 검사 결과들은 참고치 내에 있었으나, 소변검사에서 케톤이 검출되었다. 가슴X선 영상검사에서 활동성 폐병변이 관찰되지 않았고, 뇌파 검사에서 이상 소견 없었다. 뇌 자기공명영상 검사에서 뇌실질 내외의 병변은 없었다. 발작은 재발하지 않았고 입원 12병일째 퇴원하였으며 신경학적 후유증은 없었다.

시료 채취 조건 및 검사방법에 따른 지하수내 섬유상 물질 검출 양상에 관한 연구 (Effect of Sampling and Analytical Methods on the Fibrous Materials from the Ground Water)

  • 김지용;김정란;정해관;임현술;백남원
    • 한국산업보건학회지
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    • 제7권2호
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    • pp.209-222
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    • 1997
  • Authors surveyed the ground water near the waste disposed from a fiberglass production factory to confirm the presence of glassfiber in the water and to determine the effect of sampling conditions and storage on the recovery of fibrous materials in the ground water. Sample was collected at every 4 hours for 48 hours consecutively. After finishing the 48 hours sample, water sampling was done from each tap after repeated turning on and off the water for 30 seconds at each time. Sample was collected in the two 1.5 liter polyethylene bottle after vigorously shaking the bottle with the same water several times with the flowing tap water. At each paired sample, one bottle was stored stand still at room temperature, and the other sample was filtered immediately after sampling. Water was filtered on the Mixed Cellulose Ester filter with negative pressure. Each sample was divided into upper and lower layer. The other bottle was stored at room temperature standstill for 7 days and filtered in the same fashion as the other pair of sample did. Each MCE filter was divided into 4 pieces and one piece was treated with acetone to make it transparent. Each prepared sample was observed by two researchers under the light and polarizing microscopy, scanning electron microscopy and energy dispersive X-ra microanalysis. Fibers were classified by the morphology and polarizing pattern under the polarizing microscope, and count was done. 1. There was a significant fluctuation in number of the fibers, but there was no specific demonstrable pattern. 2. Non-polarizing fibers frequently disappeared after 7 days's storage. But cluster of fibers were found at the wall of the same container by scratching technique. 3. Polarizing fibers were usually found in between the filter and the manicure pasted area. Possible explanations for this phenomenon will be that either these fibers are very light or have electronic polarity. Hence, these fibers are not able to be attached on the surface of slide glass. 4. Under the scanning electron microscopic examination, the fibers which are not refractive under the light microscopy were identified as glassfiber. Other fibers which is refractive under the polarizing microscopy were identified as magnesium silicate fibers. It is strongly suggested that development of standardized method of sample collection and measurement of fibrous material in the water is needed.

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누출 수소 환기에 영향을 미치는 요인별 환기 특성에 관한 수치해석적 연구 (A Numerical Study on Ventilation Characteristics of Factors Affecting Leakages in Hydrogen Ventilation)

  • 이창용;조대환
    • 해양환경안전학회지
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    • 제28권4호
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    • pp.610-619
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    • 2022
  • 수소는 산소와 반응하여 전기에너지를 만들고 부산물로 물을 생성하므로 친환경 선박의 대체 연료로 대두되고 있다. 그러나 수소는 일반 화석연료와는 달리 낮은 점화 에너지와 높은 가연성 범위로 인하여 폭발의 위험성이 높은 물질이다. 그래서 선박에서 사용되는 수소의 안전성을 확보하기 위해서 수소의 누출·확산에 관한 유동 특성을 연구하는 것은 매우 중요하다. 본 연구에서는 선박 내부와 같은 밀폐공간에서 수소가 누출되었을 때 누출량, 통풍량, 환기 방식 등이 환기 성능에 어떤 영향을 미치는지에 대하여 수치적 해석을 수행하였다. 수치해석에는 CFD 상용 소프트웨어인 ANSYS CFX ver 18.1을 이용하였다. 누출량은 1 q = 1 g/s로 하여 1 q, 2 q, 3 q로 변경하였고, 통풍량은 1 Q = 0.91 m/s로 하여 1 Q, 2 Q, 3 Q로 변경하였으며 환기 방식은 typeI, typeII, typeIII로 변경하면서 환기 성능을 분석하였다. 누출량이 1 q에서 3 q로 증가할수록 저장실 내의 수소 몰분율(HMF)는 약 2.4 ~ 3.0배 높게 나타났으며 통풍량 증가는 누출량에 대비하여 약 62.0 ~ 64.8 % 정도 환기 성능이 개선에 효과가 있었다. 그리고 폭발의 위험성을 낮추기 위한 통풍량은 최소 2 Q 이상 되어야 하며, 수소탱크 저장실 내부의 부압 형성을 위해서는 type III가 가장 적합한 방식이라고 판단하였다.

임플랜트 식립부위 형성시 골조직의 온도변화에 관한 연구 (A STUDY ON THE TEMPERATURE CHANGES OF BONE TISSUES DURING IMPLANT SITE PREPARATION)

  • 김평일;김영수;장경수;김창회
    • 대한치과보철학회지
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    • 제40권1호
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    • pp.1-17
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    • 2002
  • The purpose of this study is to examine the possibility of thermal injury to bone tissues during an implant site preparation under the same condition as a typical clinical practice of $Br{\aa}nemark$ implant system. All the burs for $Br{\aa}nemark$ implant system were studied except the round bur The experiments involved 880 drilling cases : 50 cases for each of the 5 steps of NP, 5 steps of RP, and 7 steps of WP, all including srew tap, and 30 cases of 2mm twist drill. For precision drilling, a precision handpiece restraining system was developed (Eungyong Machinery Co., Korea). The system kept the drill parallel to the drilling path and allowed horizontal adjustment of the drill with as little as $1{\mu}m$ increment. The thermocouple insertion hole. that is 0.9mm in diameter and 8mm in depth, was prepared 0.2mm away from the tapping bur the last drilling step. The temperatures due to countersink, pilot drill, and other drills were measured at the surface of the bone, at the depths of 4mm and 8mm respectively. Countersink drilling temperature was measured by attaching the tip of a thermocouple at the rim of the countersink. To assure temperature measurement at the desired depths, 'bent-thermocouples' with their tips of 4 and 8mm bent at $120^{\circ}$ were used. The profiles of temperature variation were recorded continuously at one second interval using a thermometer with memory function (Fluke Co. U.S.A.) and 0.7mm thermocouples (Omega Co., U.S.A.). To simulate typical clinical conditions, 35mm square samples of bovine scapular bone were utilized. The samples were approximately 20mm thick with the cortical thickness on the drilling side ranging from 1 to 2mm. A sample was placed in a container of saline solution so that its lower half is submerged into the solution and the upper half exposed to the room air, which averaged $24.9^{\circ}C$. The temperature of the saline solution was maintained at $36.5^{\circ}C$ using an electric heater (J. O Tech Co., Korea). This experimental condition was similar to that of a patient s opened mouth. The study revealed that a 2mm twist drill required greatest attention. As a guide drill, a twist drill is required to bore through a 'virgin bone,' rather than merely enlarging an already drilled hole as is the case with other drills. This typically generates greater amount of heat. Furthermore, one tends to apply a greater pressure to overcome drilling difficulty, thus producing even greater amount heat. 150 experiments were conducted for 2mm twist drill. For 140 cases, drill pressure of 750g was sufficient, and 10 cases required additional 500 or 100g of drilling pressure. In case of the former. 3 of the 140 cases produced the temperature greater than $47^{\circ}C$, the threshold temperature of degeneration of bone tissue (1983. Eriksson et al.) which is also the reference temperature in this study. In each of the 10 cases requiring extra pressure, the temperature exceeded the reference temperature. More significantly, a surge of heat was observed in each of these cases This observations led to addtional 20 drilling experiments on dense bones. For 10 of these cases, the pressure of 1,250g was applied. For the other 10, 1.750g were applied. In each of these cases, it was also observed that the temperature rose abruptly far above the thresh old temperature of $47^{\circ}C$, sometimes even to 70 or $80^{\circ}C$. It was also observed that the increased drilling pressure influenced the shortening of drilling time more than the rise of drilling temperature. This suggests the desirability of clinically reconsidering application of extra pressures to prevent possible injury to bone tissues. An analysis of these two extra pressure groups of 1,250g and 1,750g revealed that the t-statistics for reduced amount of drilling time due to extra pressure and increased peak temperature due to the same were 10.80 and 2.08 respectively suggesting that drilling time was more influenced than temperature. All the subsequent drillings after the drilling with a 2mm twist drill did not produce excessive heat, i.e. the heat generation is at the same or below the body temperature level. Some of screw tap, pilot, and countersink showed negative correlation coefficients between the generated heat and the drilling time. indicating the more the drilling time, the lower the temperature. The study also revealed that the drilling time was increased as a function of frequency of the use of the drill. Under the drilling pressure of 750g, it was revealed that the drilling time for an old twist drill that has already drilled 40 times was 4.5 times longer than a new drill The measurement was taken for the first 10 drillings of a new drill and 10 drillings of an old drill that has already been used for 40 drillings. 'Test Statistics' of small samples t-test was 3.49, confirming that the used twist drills require longer drilling time than new ones. On the other hand, it was revealed that there was no significant difference in drilling temperature between the new drill and the old twist drill. Finally, the following conclusions were reached from this study : 1 Used drilling bur causes almost no change in drilling temperature but increase in drilling time through 50 drillings under the manufacturer-recommended cooling conditions and the drilling pressure of 750g. 2. The heat that is generated through drilling mattered only in the case of 2mm twist drills, the first drill to be used in bone drilling process for all the other drills there is no significant problem. 3. If the drilling pressure is increased when a 2mm twist drill reaches a dense bone, the temperature rises abruptly even under the manufacturer-recommended cooling conditions. 4. Drilling heat was the highest at the final moment of the drilling process.

무가압 어닐드한 Sic-$TiB_2$ 전도성 복합체의 특성에 미치는 In Situ YAG의 영향 (Effects of In Situ YAG on Properties of the Pressurless Annealed Sic-$TiB_2$ Electroconductive Ceramic Composites)

  • 신용덕;주진영;고태헌
    • 전기학회논문지
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    • 제57권5호
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    • pp.808-815
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    • 2008
  • The composites were fabricated 61[vol.%] ${\beta}$-SiC and 39[vol.%] $TiB_2$ powders with the liquid forming additives of 8, 12, 16[wt%] $Al_2O_3+Y_2O_3$ as a sintering aid by pressureless annealing at 1650[$^{\circ}C$] for 4 hours. The present study investigated the influence of the content of $Al_2O_3+Y_2O_3$ sintering additives on the microstructure, mechanical and electrical properties of the pressureless annealed SiC-$TiB_2$ electroconductive ceramic composites. Reactions between SiC and transition metal $TiB_2$ were not observed in the microstructure and the phase analysis of the pressureless annealed SiC-$TiB_2$ electroconductive ceramic composites. Phase analysis of SiC-$TiB_2$ composites by XRD revealed mostly of ${\alpha}$-SiC(6H), ${\beta}$-SiC(3C), $TiB_2$, and In Situ YAG($Al_2Y_3O_{12}$). The relative density of SiC-$TiB_2$ composites was lowered due to gaseous products of the result of reaction between SiC and $Al_2O_3+Y_2O_3$. There is another reason which pressureless annealed temperature 1650[$^{\circ}C$] is lower $300{\sim}450[^{\circ}C]$ than applied pressure sintering temperature $1950{\sim}2100[^{\circ}C]$. The relative density, the flexural strength, the Young's modulus and the Vicker's hardness showed the highest value of 82.29[%], 189.5[Mpa], 54.60[Gpa] and 2.84[Gpa] for SiC-$TiB_2$ composites added with 16[wt%] $Al_2O_3+Y_2O_3$ additives at room temperature. Abnormal grain growth takes place during phase transformation from ${\beta}$-SiC into ${\alpha}$-SiC was correlated with In Situ YAG phase by reaction between $Al_2O_3$ and $Y_2O_3$ additive during sintering. The electrical resistivity showed the lowest value of 0.0117[${\Omega}{\cdot}cm$] for 16[wt%] $Al_2O_3+Y_2O_3$ additives at 25[$^{\circ}C$]. The electrical resistivity was all negative temperature coefficient resistance (NTCR) in the temperature ranges from $25^{\circ}C$ to 700[$^{\circ}C$]. The resistance temperature coefficient of composite showed the lowest value of $-2.3{\times}10^{-3}[^{\circ}C]^{-1}$ for 16[wt%] additives in the temperature ranges from 25[$^{\circ}C$] to 100[$^{\circ}C$].

국내 의료기관의 의료관련감염 관리 실태 (The status of Healthcare-associated Infection Control among Healthcare Facilities in Korea)

  • 정선영;김옥선;이지영
    • 디지털융복합연구
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    • 제12권5호
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    • pp.353-366
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    • 2014
  • 본 연구는 국내 의료기관의 의료관련감염 관리 현황을 파악하고자 시행된 조사연구이다. 134개 의료기관을 대상으로 강문원 등[8]이 개발한 설문지를 보완하여 사용하였다. 조사대상 의료기관의 평균 병상수는 556.4이었고 300병상 미만 의료기관이 26.9%를 차지하였다. 99.3%의 의료기관이 감염관리위원회를 설치하였고 평균 개최 횟수는 연 3.4회였다. 감염관리실무자가 1명 배치된 곳이 54.5%, 전담근무가 62.7%이었다. 실무자의 95.5%가 간호사로 평균 37.2세, 48.9%가 석사 이상, 평균 병원 경력은 13.5년, 감염관리실무 경력은 3.2년이었으며 30.8%가 1년 미만이었다. 감염감시는 100%, 개선활동은 75.4%의 의료기관에서 수행하였다. 감염관리실 설치 및 인력, 감염관리실무자 근무 형태, 감염감시 결과 비교, 감염유행조사, 음압병실, 감염관리 전산프로그램과 손위생 모니터링 실시는 의료기관의 규모에 따라 유의한 차이가 있었으며, 300병상 미만 중소 의료기관에서 인력, 조직, 시설이 부족하였다. 본 연구의 결과는 300병상 미만 중소 의료기관의 감염관리 조직과 인력, 실무 정착화를 위한 기초 자료로 이용될 수 있을 것이다.

말기암환자에서 임박사건 간 48시간 임종예측도 비교 (Predictability of Impending Events for Death within 48 Hours in Terminal Cancer Patients)

  • 황인철;최충현;김경곤;이경식;서희선;심재용
    • Journal of Hospice and Palliative Care
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    • 제14권1호
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    • pp.28-33
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    • 2011
  • 목적: 임박사건(impending event)에 대한 인지는 보호자와의 보다 효과적인 의사소통을 위해 필요할 뿐 아니라, 임종실로 옮기는 시점을 결정하는데 있어서 매우 중요하다. 이 주제에 대한 지금까지의 연구는 대부분 임종 48시간을 전후한 시점에서 이미 '발생되어 있는' 증상의 나열에 불과하였다. 이에 '변화'의 시점에서 사망까지의 시간을 기준으로 하여 임박사건 간 48시간 이내 임종예측도를 비교하였다. 방법: 인천소재 완화의료병동에서 임종을 맞이한 160명의 환자 중 임종 전 일주일 동안의 의무기록이 있는 80명을 대상으로 하였다. 환자 및 보호자가 호소하는 주관적 증상 9가지와 의료인에 의해 관찰되는 객관적 징후 8가지를 선정하고 각 항목에 대한 '의미 있는 변화'의 기준을 사전에 정하였다. 결과: 증상에서는 수면량의 증가(53.8%), 징후에서는 혈압의 감소(87.5%)가 가장 높은 발생빈도를 보였다. 임종까지의 평균시간은 증상의 경우 안정 시 호흡곤란(46.8시간)이, 징후의 경우 산소포화도의 감소(13.6시간)와 혈압의 감소(36.9시간)가 48시간 이내였다. 48시간 임박사건으로서의 예측도는 증상의 경우, 양성예측도는 안정 시 호흡곤란이 가장 높았고(83%) 음성예측도는 안정 시 호흡곤란과 의식혼탁/섬망의 조합이 가장 높았으며(86%), 징후의 경우 양성 예측도는 모두 95% 이상이었고 음성예측도는 혈압의 감소와 산소포화도 감소의 조합에서 가장 높았다(60%). 증상과 징후의 발생양상은 유의한 차이를 보였다. 결론: 증상에서는 안정 시 호흡곤란과 의식혼탁/섬망이, 징후에서는 산소포화도나 혈압의 감소가 임종임박을 예측하는데 가장 유용한 임상지표로 생각된다.

호흡곤란을 주소로 내원한 환자에서 혈청 B-type Natriuretic Peptide 검사의 유용성 : 폐성심과 좌심부전의 감별에 대하여 (The Application of B-Type Natriuretic Peptide Level of the Dyspneic Patients : Differentiation Between Cor Pulmonale and Left Ventricular Dysfunction)

  • 박홍훈;김세현;최정은;김강호;천석철;이지현;이용구;김인재;차동훈;홍상범;이지현
    • Tuberculosis and Respiratory Diseases
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    • 제54권3호
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    • pp.320-329
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    • 2003
  • 연구배경 : 혈청 내 B-type natriuretic peptide (BNP)는 심실의 부피 증가나 압력 부하에 의해 주로 심실에서 분비된다. 몇몇의 보고에서 호흡곤란을 주소로 응급실에 내원한 환자들에서 BNP의 측정이 심부전과 폐질환을 감별하는데 도움이 된다고 보고하였다. 저자들은 호흡곤란을 주소로 내원한 환자에서 BNP의 측정이 우심실부전과 좌심실부전의 감별에 도움이 될 수 있는지를 알고자 이 연구를 시작하게 되었다. 방 법 : 포천중문의대 분당차 병원에 2002년 6월에서 2003년 3월까지 호흡곤란을 주소로 응급실을 내원한 환자 89명과, 정상 대조군으로 29명에서 방사선면역측정법을 이용하여 BNP를 측정하였다. 결 과 : 호흡곤란을 주소로 내원한 좌심실부전군(1군)과 우심실부전군(2군) 사이에는 유의한 BNP 값의 차이($682{\pm}314$ pg/mL vs. $149{\pm}94$ pg/mL, p=0.000)가 있었다. ROC 곡선을 이용하여 BNP 기준값을 219 pg/mL로 했을 때 좌심실부전군과 우심실부전군을 감별할 수 있는 민감도는 94.3%, 특이도는 92.9%, 양성 예측도는 97%, 그리고 음성 예측도는 86.7%였다. 결 론 : BNP는 호흡곤란을 주소로 응급실을 내원한 환자에서 좌심실부전과 우심실부전을 감별하는데 도움을 줄 수 있는 빠르고 유용한 검사방법이다.