• 제목/요약/키워드: Natural Breaks

검색결과 51건 처리시간 0.033초

Effect of electromagnetic field exposure on the reproductive system

  • Gye, Myung-Chan;Park, Chan-Jin
    • Clinical and Experimental Reproductive Medicine
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    • 제39권1호
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    • pp.1-9
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    • 2012
  • The safety of human exposure to an ever-increasing number and diversity of electromagnetic field (EMF) sources both at work and at home has become a public health issue. To date, many in vivo and in vitro studies have revealed that EMF exposure can alter cellular homeostasis, endocrine function, reproductive function, and fetal development in animal systems. Reproductive parameters reported to be altered by EMF exposure include male germ cell death, the estrous cycle, reproductive endocrine hormones, reproductive organ weights, sperm motility, early embryonic development, and pregnancy success. At the cellular level, an increase in free radicals and $[Ca^{2+}]i$ may mediate the effect of EMFs and lead to cell growth inhibition, protein misfolding, and DNA breaks. The effect of EMF exposure on reproductive function differs according to frequency and wave, strength (energy), and duration of exposure. In the present review, the effects of EMFs on reproductive function are summarized according to the types of EMF, wave type, strength, and duration of exposure at cellular and organism levels.

NIH3T3 세포에서 UVB에 의한 세포고사와 DNA 단사절단에 미치는 fisetin의 효과 (Effect of fisetin on UVB-induced apoptosis and DNA single strand breaks in NIH3T3 cells)

  • 정세진;김돈영;한설희;신상민;차재영;박노복;이정섭;박종군
    • 생명과학회지
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    • 제17권1호
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    • pp.64-69
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    • 2007
  • 본 연구에서는 UVB에 조사된 NIH3T3 세포에서 세포고사와 DNA 단사절단에 미치는 fisetin후처리의 효과에 대해서 연구하였다. 세포에 UVB $(200J/m^2)$를 조사하고 정상배지에서 48시간 배양한 세포의 세포고사에 수반되는 핵분절은 50% 정도의 세포에서 관찰되었다. 흥미롭게도 배양배지에 fisetin이 첨가될 경우 핵분절을 보이는 세포의 빈도는 상당한 감소를 보였다. 알칼리 아가로스 겔에 의한 DNA 단사절단 분석에서 자외선 조사 후 fisetin처리는 정상배지 배양시보다 단사절단의 빈도를 감소시켜 DNA크기의 증가를 유도하였는데 이는 fisetin이 UVB에 의한 DNA 상해의 회복에 긍정적 효과를 나타냄을 시사한다 Western blot 분석에 의해 fisetin은 자외선 조사에 의해 활성화되는 p53의 수준을 유의한 수준으로 감소시키며 자외선 상해의 결과 세포주기의 정지에 수반되는 PCNA의 감소 경향을 다소 완화시켰다. 이러한 결과들은 fisetin이 DNA 회복의 활성을 통해 세포고사의 감소에 기여하며 이 과정에서 p53 및 PCNA의 수준변화와 관련하여 행동함을 시사한다.

영어 뉴스와 자연발화에 나타나는 고성조 피치액센트의 차이점 (Differences in High Pitch Accents between News Speech and Natural Speech)

  • 최윤희;이주경
    • 음성과학
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    • 제12권2호
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    • pp.17-28
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    • 2005
  • This paper argues that news speech entails a distinct intonational pattern from natural speech, effectively reflecting that it primarily focuses on providing new information. We conducted a phonetic experiment to compare the tonal contours between news speech and natural speech, examining the distributions of pitch accents and the overall pitch ranges. We utilized 70 American Press (AP) radio news utterances and 70 natural utterances extracted from TV dramas. Results show that news speech involves 3.38 H*'s (including L+H* and !H*) within an intonational phrase (IP) or intermediate phrase (ip) whereas natural speech, 1.8 in average. The number of IP/ip's per sentence is 3 in news speech, which is shown in the highest rate of 32.07% of the news speech, but it is merely 1, taking up the highest 41.42% in natural speech. Next, declination tends to be prevented in news speech, and the pitch range is much greater in news speech than in natural speech. Finally, a secondary stress syllable is comparatively frequently given a pitch accent in news speech, explicitly distinct from natural speech. These results can be interpreted as stating that news has the particular purpose of providing new information; every content word tends to be given a H* or its related pitch accent like L+H* or !H* because news speech assumes that every word conveys new information. This definitely brings about more IP/ip's per sentence due to a human physiological constraint; that is, more H*'s will cause more respiratory breaks. Also, greater pitch ranges and pitch accents imposed on secondary stress may be attributed to exaggerating new information.

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장예모의 인상(印象) 시리즈 <인상유삼저>에 관한 연구 (Research on Impression Liu Sanjie from impression series by Zhang Yimou)

  • 왕지권
    • 트랜스-
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    • 제5권
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    • pp.65-82
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    • 2018
  • 장예모 감독의 작품 <인상유삼저>가 기존의 공연들과 차별화되는 가장 큰 특징은 무대공간의 활용에 있다. 인상시리즈의 무대는 세트장과 대자연과 결합하여 전통적인 무대공연양식에서 탈피하여 자연환경을 무대배경으로 완성하였다. 또한 자신만의 특색 있는 미적 감각과 자연공간을 조화시켜 해당 지역문화의 특색을 반영해 내었다. <인상유삼저>는 실제 자연경관을 배경으로 하는 단순한 산수공연이 아니라 자연적인 색채와 공간이 조화를 이루어 나타내는 인간과 자연사이의 친환경적 개념에서 비롯되어 해당 지역사회의 문화산업적 요소를 홍보하는 기능으로 작용하기도 하였다. 본 연구는 문화인류학자 홀의 프록세믹스(proxemics) 개념과 친환경적 측면에서 <인상유삼저>를 분석하였다. <인상유삼저>는 자연환경을 배경으로 하는 실경산수공연의 형식으로 연출하며 해당 지역사회의 문화와 자연적 특성을 최대한 보존하는 동시에 현지문화산업의 홍보측면에도 기여하였다. <인상유삼저>는 실경산수공연으로서 인간과 자연을 성공적으로 융합하여 환경을 보존하였다는 데에도 의의를 갖고 있다.

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An Integrated Approach in the Pest Management in Sericulture

  • Singh, R.N.;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • 제5권2호
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    • pp.141-151
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    • 2002
  • The success of sericulture industry in India is mainly attributed to the well-planned annual sericultural activity and the systematic implementation of pest preventive and control measures. The insect spectrum of silkworm and its food plants is complex and plays a major role in limiting the production of silk. Insects cause extensive damage to plant whereas predators and parasites either kill the silkworm larvae or force them to spin flimsy cocoons. Unilateral control measure against this pest is mainly based on the use of synthetic organic insecticides. Though these approaches initially paid rich dividends, the undesirable consequences soon surfaced. Insecticide induced resurgence of gall midges, leafhopper, leaf roller, secondary pest out breaks and development of pest biotypes has led to realization of Integrated Pest Management in sericulture. Various components of IPM, viz. Host plant resistance, cultural practices, biological control, chemical control and integrating them at various technological levels have been studied. Sources of host plant resistance have been identified for some of the major insect pests. High yielding mulberry variety has been propagated and their resistances towards major pests have been recorded. Cultural practices like pruning, pollarding, judicious use of nitrogen, optimum spacing and weed management have preyed to be the powerful tools in containing pests. Natural control over the pest population build- up exerted by the wide range of parasitoids, predators and pathogens has been well documented with identification of natural enemies and studies on their potential. Augmentation, through inoculation or inundative releases of parasitic arthropods, is the most direct way of increasing the numbers of these beneficials in sericulture.

느릅나무껍질과 꼭두서니 복합추출물을 이용한 천연염색 한복형 휴식복 디자인 (Design of Natural Dyeing Hanbok-Type Leisurewear Using Elm Bark and Rubia akane Nakai Composite Extracts)

  • 장현주
    • 한국의류산업학회지
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    • 제23권2호
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    • pp.151-158
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    • 2021
  • The purpose of this study was to develop high-quality naturally dyed leisurewear with images of traditional Korean clothing that keeps a psychologically comfortable and physically pleasant environment at home and in vacation spots. The root bark of elm trees, the atopic skin, is also known to be effective for the relief of rhinitis and atopic diseases as well as stress and insomnia. However, there is insufficient color in the bark for the dyeing of fashion products, so to compensate for the lack of color, for dyeing purposes it was combined with a composite extract called Rubia akane Nakai resulting in a relatively bright red color. Except for the light fastness, all the fastnesses were rated 4 to 5, showing excellent results. Through complex dyeing using elm bark and pods extract the author produced four high-quality vests, one-piece, a gown, and jeogori-pantsuits of silk materials with Korean images that are suitable wear for relaxing comfortably at home and during breaks and which provide a comfortable and physically pleasant experience. The vest was made with the formal style of Bae-ja and Dang-eu, the dress is made of Cheok-lik, and the gown is made of Wonsam. It will be meaningful at a time when the importance of rest is increasing due to the healing clothes worn by busy modern people.

DNA Topoisomerase I Inhibitory Activity of Stilbenes and Oligostilbenes from Leaf and Stem of Vitis amurensis

  • Kang, Na-Na;Ha, Do Thi;Park, Chang-Sik;Myung, Pyung-Keun;Bae, Ki-Hwan
    • Natural Product Sciences
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    • 제16권4호
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    • pp.223-227
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    • 2010
  • The DNA Topoisomerase I (DNA Topo I) inhibitory effect of ten isolated compounds (1.10) from the leaf and stem of Vitis amurensis were examined. Among them, amurensin G (5) and r-2-viniferin (7) showed high potent inhibitory activity against DNA Topo I. DNA Topo I, an important target for anticancer drugs, can cause DNA breaks and play a key role during cell proliferation, transcription and repair. Thus, the results suggest that the selected compounds (5 and 7) from Vitis amurensis have a possibility as DNA Topo I-targeting anticancer agents.

일본어 TTS의 가변 Break를 이용한 합성단위 선택 방법 (A Unit Selection Methods using Variable Break in a Japanese TTS)

  • 나덕수;배명진
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2008년도 하계종합학술대회
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    • pp.983-984
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    • 2008
  • This paper proposes a variable break that can offset prediction error as well as a pre-selection methods, based on the variable break, for enhanced unit selection. In Japanese, a sentence consists of several APs (Accentual phrases) and MPs (Major phrases), and the breaks between these phrases must predicted to realize text-to-speech systems. An MP also consists of several APs and plays a decisive role in making synthetic speech natural and understandable because short pauses appear at its boundary. The variable break is defined as a break that is able to change easily from an AP to an MP boundary, or from an MP to an AP boundary. Using CART (Classification and Regression Trees), the variable break is modeled stochastically, and then we pre-select candidate units in the unit-selection process. As the experimental results show, it was possible to complement a break prediction error and improve the naturalness of synthetic speech.

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염색체 말단부위 (Back to the Ends: Chromosomal DNA)

  • 이미형;서동철
    • Childhood Kidney Diseases
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    • 제12권1호
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    • pp.1-10
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    • 2008
  • Nucleic scids transfer the genetic information for serving a central biological purpose. The nucleic acids are polymers of nucleotides and they are mainly ribonucleic acid(RNA) and deoxyribonucleic acid(DNA). The nucleotides are stoichiometrically composed of five-carbon sugars, nitrogeneous bases, and phosphoric acids. The chemistry of nucleic acids and characteristics of different genomes are decribed for further study. Most of DNA genomes tend to be circular including bacterial genomes and eukaryotic mitochondrial DNA. Eukaryotic chromosomes in cells, in contrast, are generally linear. The ends of linear chromosomes are called telomeres. The genomes of different species, such as mammals, plants, invertebrates can be compared with the chromosome ends. The telomeric complex allows cells to distinguish the random DNA breaks and natural chromosomal ends. The very ends of chromosomes cannot be replicated by any ordinary mechanisms. The shortening of telomeric DNA templates in semiconservative replication is occurred with each cell division. The short telomere length is critically related to aging, tumors and dieases.

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Implementation of Occupant Density and Walking Pattern Measurement for Emergency Evacuation and Safety in High-Rise Multi-Purpose Facilities

  • Lee, Myung Sik
    • 국제초고층학회논문집
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    • 제7권4호
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    • pp.409-415
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    • 2018
  • Recently, many countries around the world began to show interest in safety against terrorism, fire, and natural disasters. This study aimed to propose a quantitative measurement system for emergency evacuation and safety for various kinds of terrorism and fire within high-rise multi-purpose facilities, which can measure the pedestrians' ordinary walking patterns in the concourse with the highest pedestrian volume out of all the spaces within multi-story buildings, predict pedestrians' evacuation walking lines when a sudden disaster breaks out, and analyze the gait coefficient, occupant density, and evacuation behavior time.