• 제목/요약/키워드: Nano safety

검색결과 219건 처리시간 0.026초

Studies on the Toxicity and Distribution of Indium Compounds According to Particle Size in Sprague-Dawley Rats

  • Lim, Cheol Hong;Han, Jeong-Hee;Cho, Hae-Won;Kang, Mingu
    • Toxicological Research
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    • 제30권1호
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    • pp.55-63
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    • 2014
  • Objectives: The use of indium compounds, especially those of small size, for the production of semiconductors, liquid-crystal panels, etc., has increased recently. However, the role of particle size or the chemical composition of indium compounds in their toxicity and distribution in the body has not been sufficiently investigated. Therefore, the aim of this study was to examine the effects of particle size and the chemical composition of indium compounds on their toxicity and distribution. Methods: Male Sprague-Dawley rats were exposed to two different-sized indium oxides (average particle sizes under 4,000 nm [IO_4000] and 100 nm [IO_100]) and one nano-sized indium-tin oxide (ITO; average particle size less than 50 nm) by inhalation for 6 hr daily, 5 days per week, for 4 weeks at approximately $1mg/m^3$ of indium by mass concentration. Results: We observed differences in lung weights and histopathological findings, differential cell counts, and cell damage indicators in the bronchoalveolar lavage fluid between the normal control group and IO- or ITO-exposed groups. However, only ITO affected respiratory functions in exposed rats. Overall, the toxicity of ITO was much higher than that of IOs; the toxicity of IO_4000 was higher than that of IO_100. A 4-week recovery period was not sufficient to alleviate the toxic effects of IO and ITO exposure. Inhaled indium was mainly deposited in the lungs. ITO in the lungs was removed more slowly than IOs; IO_4000 was removed faster than IO_100. IOs were not distributed to other organs (i.e., the brain, liver, and spleen), whereas ITO was. Concentrations of indium in the blood and organ tissues were higher at 4 weeks after exposure. Conclusions: The effect of particle size on the toxicity of indium compounds was not clear, whereas chemical composition clearly affected toxicity; ITO showed much higher toxicity than that of IO.

MULTI-SCALE MODELING AND ANALYSIS OF CONVECTIVE BOILING: TOWARDS THE PREDICTION OF CHF IN ROD BUNDLES

  • Niceno, B.;Sato, Y.;Badillo, A.;Andreani, M.
    • Nuclear Engineering and Technology
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    • 제42권6호
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    • pp.620-635
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    • 2010
  • In this paper we describe current activities on the project Multi-Scale Modeling and Analysis of convective boiling (MSMA), conducted jointly by the Paul Scherrer Institute (PSI) and the Swiss Nuclear Utilities (Swissnuclear). The long-term aim of the MSMA project is to formulate improved closure laws for Computational Fluid Dynamics (CFD) simulations for prediction of convective boiling and eventually of the Critical Heat Flux (CHF). As boiling is controlled by the competition of numerous phenomena at various length and time scales, a multi-scale approach is employed to tackle the problem at different scales. In the MSMA project, the scales on which we focus range from the CFD scale (macro-scale), bubble size scale (meso-scale), liquid micro-layer and triple interline scale (micro-scale), and molecular scale (nano-scale). The current focus of the project is on micro- and meso-scales modeling. The numerical framework comprises a highly efficient, parallel DNS solver, the PSI-BOIL code. The code has incorporated an Immersed Boundary Method (IBM) to tackle complex geometries. For simulation of meso-scales (bubbles), we use the Constrained Interpolation Profile method: Conservative Semi-Lagrangian $2^{nd}$ order (CIP-CSL2). The phase change is described either by applying conventional jump conditions at the interface, or by using the Phase Field (PF) approach. In this work, we present selected results for flows in complex geometry using the IBM, selected bubbly flow simulations using the CIP-CSL2 method and results for phase change using the PF approach. In the subsequent stage of the project, the importance of effects of nano-scale processes on the global boiling heat transfer will be evaluated. To validate the models, more experimental information will be needed in the future, so it is expected that the MSMA project will become the seed for a long-term, combined theoretical and experimental program.

Selective Laser Melting 방식으로 적층제조된 Inconel 718 합금의 조사 경화 특성 (Irradiation Hardening Property of Inconel 718 Alloy produced by Selective Laser Melting)

  • 서주원;임상엽;진형하;천영범;강석훈;한흥남
    • 한국분말재료학회지
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    • 제30권5호
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    • pp.431-435
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    • 2023
  • An irradiation hardening of Inconel 718 produced by selective laser melting (SLM) was studied based on the microstructural observation and mechanical behavior. Ion irradiation for emulating neutron irradiation has been proposed owing to advantages such as low radiation emission and short experimental periods. To prevent softening caused by the dissolution of γ' and γ" precipitates due to irradiation, only solution annealing (SA) was performed. SLM SA Inconel 718 specimen was ion irradiated to demonstrate the difference in microstructure and mechanical properties between the irradiated and non-irradiated specimens. After exposing specimens to Fe3+ ions irradiation up to 100 dpa (displacement per atom) at an ambient temperature, the hardness of irradiated specimens was measured by nano-indentation as a function of depth. The depth distribution profile of Fe3+ and dpa were calculated by the Monte Carlo SRIM (Stopping and Range of Ions in Matter)-2013 code under the assumption of the displacement threshold energy of 40 eV. A transmission electron microscope was utilized to observe the formation of irradiation defects such as dislocation loops. This study reveals that the Frank partial dislocation loops induce irradiation hardening of SLM SA Inconel 718 specimens.

Simulation of Hydrogen Transport in a Single-walled Carbon Nanotube for Storage Safety

  • Oh, Kyung-Su;Kim, Dong-Hyun;Park, Seung-Ho;Kim, Jung-Soo
    • International Journal of Safety
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    • 제6권1호
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    • pp.16-21
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    • 2007
  • Carbon nanotubes hold much promise as future materials for safe storage of hydrogen. In this paper, hydrogen transport mechanisms in single-walled carbon nano-tubes (SWNTs) for various temperatures and chiral indices were studied using molecular dynamics simulation method. The SWNT models of zigzag (10,0), chiral (10,5) and armchair (10,10) with hydrogen molecules inside were simulated at temperatures ranging from 253K to 373K. Movements of hydrogen molecules ($H_2$) inside a SWNT were analyzed using mean-square displacements and velocity autocorrelation functions.

Balancing 모듈 설계를 위한 Differential Gear System의 구조해석에 관한 연구 (Structural Analysis of Differential Gear System for Balancing Module Design)

  • 장태환;김동준;문창호;이성재;김태규
    • 열처리공학회지
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    • 제32권6호
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    • pp.270-274
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    • 2019
  • In this study, simulation structure analysis was performed for the differential gear system for passenger cars as a prerequisite for the design of the balancing module. The differential gear system was modeled by using CATIA and simulation structure analysis was performed using ANSYS software. The material of the modeled differential gear system uses the mechanical properties of S45C (Q&T). In the structural analysis of the differential gear, the areas where the maximum stress and the maximum strain occurred can be identified. The maximum stress and maximum strain occurred in the pitch circle of the bevel gear. In evaluating the safety factor, it was found that sufficient safety factor was secured. Based on the analysis results for the differential gear, it is expected that it will be a good reference if we design the balancing module device.

Application of nanocomposite material to avoid injury by physical sports equipment

  • Weifeng Qin;Zhubo Xu
    • Advances in nano research
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    • 제14권2호
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    • pp.195-200
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    • 2023
  • Safety in sports is important because if an athlete has an accident, he may not be able to lead an everyday life for the rest of his life. The safety of sports facilities is very effective in creating people's sports activities, with the benefits of staying away from physical injury, enjoying sports, and mental peace. Everyone has the right to participate in sports and recreation and to ensure that they want a safe environment. This study prepares a very good Nickel-Cobalt -Silicon carbide (Ni/Co-SiC) nanocomposite with convenient geometry on the leg press machine rod, employing the pulse electrodeposition technique to reduce the rod's wear and increase the durability of sports equipment and control sports damages. The results showed that the Ni/Co-SiC nanocomposite formed at 2 A/dm2 shows extraordinary microhardness. The wear speed for the Ni/Co-SiC nanocomposite created at 4 A/dm2 was 15 mg/min, showing superior wear resistance. Therefore, the Ni/Co-SiC nanocomposite can reduce sports equipment's wear and decrease sports injuries. Ni-Co/SiC nanocomposite layers with various scopes of silicon carbide nanoparticles via electrodeposition in a Ni-Co plating bath, including SiC nanoparticles to be co-deposited. The form and dimensions of Silicon carbide nanoparticles are watched and selected using Scanning Electron Microscopy (SEM).

Real-time Intelligent Exit Path Indicator Using BLE Beacon Enabled Emergency Exit Sign Controller

  • Jung, Joonseok;Kwon, Jongman;Jung, Soonho;Lee, Minwoo;Mariappan, Vinayagam;Cha, Jaesang
    • International journal of advanced smart convergence
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    • 제6권1호
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    • pp.82-88
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    • 2017
  • Emergency lights and exit signs are an indispensable part of safety precautions for effective evacuation in case of emergency in public buildings. These emergency sign indicates safe escape routes and emergency doors, using an internationally recognizable sign. However visibility of those signs drops drastically in case of emergency situations like fire smoke, etc. and loss of visibility causes serious problems for safety evacuation. This paper propose a novel emergency light and exit sign built-in with Bluetooth Low Energy (BLE) Beacon to assist the emergency self-guiding evacuation using devices for crisis and emergency management to avoid panic condition inside the buildings. In this approach, the emergency light and exit sign with the BLE beacons deployed in the indoor environments and the smart devices detect their indoor positions, direction to move, and next exit sign position from beacon messages and interact with map server in the Internet / Intranet over the available LTE and/or Wi-Fi network connectivity. The map server generate an optimal emergency exit path according to the nearest emergency exit based on a novel graph generation method for less route computation for each smart device. All emergency exit path data interfaces among three system components, the emergency exit signs, map server, and smart devices, have been defined for modular implementation of our emergency evacuation system. The proposed exit sign experimental system has been deployed and evaluated in real-time building environment thoroughly and gives a good evidence that the modular design of the proposed exit sign system and a novel approach to compute emergency exit path route based on the BLE beacon message, map server, and smart devices is competitive and viable.

Potential Health-Promoting Benefits of Paraprobiotics, Inactivated Probiotic Cells

  • Akter, Shahina;Park, Jong-Hyun;Jung, Hoo Kil
    • Journal of Microbiology and Biotechnology
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    • 제30권4호
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    • pp.477-481
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    • 2020
  • Viability plays an important role in the beneficial microbes (probiotics) to produce health benefits. However, this idea has been changed after the invention of the term "paraprobiotics," indicating that non-viable microbes could produce health benefits similar to those produced by live probiotics. Occasionally, it might be dangerous to administer live probiotics to people with weak immunity. In such cases, ingestion of paraprobiotics could be a potential alternative. The definition of paraprobiotics refers to the use of inactivated (non-viable) microbial cells or cell fractions to provide health benefits to the consumer. Paraprobiotics have attracted much attention because of their long shelf life, safety, and beneficial effects, such as modulation of immunity, modification of biological responses, reduction of cholesterol, anti-inflammatory, and antiproliferative properties. These features indicate that paraprobiotics may play a vital role in improving the health of the consumer by enhancing particular physiological functions, even though the exact underlying mechanisms have not yet been completely elucidated. In this mini-review, we briefly discuss the historical backgrounds of paraprobiotics and evidence of their health-promoting effects, prophylactic, and therapeutic properties.

인덕션 조리용기용 도전성 Paste의 Silver 및 Glass Frit 함량 변화에 따른 미세구조 및 전기적 특성 고찰 (Fabrication of Conductive Pastes for Induction Cookware with the Variation of the Contents of Silver Powder and Glass Frit)

  • 구현호;김봉호;윤영준
    • 한국전기전자재료학회논문지
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    • 제29권11호
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    • pp.690-695
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    • 2016
  • Induction cooktop has a great attention due to its safety, quick heating and cleanness compared to gas oven. However, the materials for induction cookware is limited to steel or stainless-steel which has the magnetic property. Recently, it has been tried to apply various porcelain to induction cookware after printing the silver layer on the bottom of cookware plates and co-firing at high temperature. Glass frits are added in the silver paste to improve an adhesion force between porcelain materials containers and transferred silver layer. The hybrid silver pastes for induction cookware requires the proper electrical resistance and the thermal conductivity with base plates. After sintering process at $800^{\circ}C$, a part of melted glass migrated to the porcelain and the rest of the glass frit was exposed to the surface. It was confirmed that most of the glass frit formed an adhesion layer between the porcelain and transferred silver layer that enhances the adhesion force.

The Characteristic of Titanium Composites Including of Nano-sized TiNx for Stack Separator

  • Park, Sung-Bum;Ban, Tae-Ho;Woo, Heung-Sik;Kim, Sung-Jin
    • 한국분말재료학회지
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    • 제17권2호
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    • pp.123-129
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    • 2010
  • The fabrication of interconnect from titanium powders and $TiN_x$ powders is investigated. Corrosion-resistant titanium and $TiN_x$ are used as reinforcement in order to reveal high heat and corrosion resistance at the elevated temperature. We fabricated the plates for interconnect reinforced with $TiN_x$ by mixing titanium powders with 10 wt.% of nano-sized $TiN_x$. Spark Plasma Sintering (SPS) was chosen for the sintering of these composites. The plate made of titanium powders and $TiN_x$ powders demonstrates higher corrosion resistance than that of the plate of titanium powders alone. The physical properties of specimens were analyzed by performing hardness test and biaxial strength test. The electrochemical properties, such as corrosion resistance and hydrogen permeability at high temperature, were also investigated. The microstructures of the specimens were investigated by FESEM and profiles of chemical compositions were analyzed by EDX.