• 전자공학회논문지C
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• 제36C권8호
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• pp.10-21
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• 1999

본 논문에서는 12비트의 해상도와 65MHz의 변환속도를 가지면서 단일 3.3V의 공급전압으로 동작하는 전류 셀 매트릭스 구조의 CMOS D/A 변환기를 제안하였다. 설계된 CMOS D/A 변환기는 우수한 단조증가성과 빠른 정착시간을 가지는 전류 셀 매트릭스 구조의 장점을 이용하면서 기존의 D/A 변환기의 전류셀 간의 문턱전압의 부정합과 접지선의 전압 강하에 의한 오차를 감소시키기 위해 트리 구조 바이어스 회로, 대칭적 접지선 연결, 캐스코드 전류 스위치를 사용하여 구현되었다. 설계된 전류 셀 매트릭스 12비트 D/A 변환기를 $0.6{\mu}m$ CMOS n-well 공정을 이용하여 제작하였다. 제작된 DAC칩을 +3.3V 단일 공급전원을 이용하여 측정한 결과, 정착시간이 20nsec로써 50MHz의 변환속도와 35.6mW의 전력소모를 나타내었다. 또한 측정된 SNR, DNL은 각각 55 dB, ${\pm}0.5LSB$,${\pm}2LSB$를 나타내었다.

• Clinical and Experimental Reproductive Medicine
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• 제29권4호
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• pp.237-243
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• 2002

Objective : The aim of this study was to evaluate the influence of different media on blastulation, mean cell number, percentage of inner cell mass (ICM) of total cells and ICM : trophectoderm (TE) ratio in mice. Materials and methods: A total 552 two cell embryos were retrieved from ICR female mice (4 weeks old) at 48 hr after hCG injection (mated just after hCG injection) and cultured in MEM (n=276) or TCM (n=276) supplemented with 20% hFF. The grading of blastocysts from zona-intact (ZiB) to -escape (hatching and hatched, ZeB) was performed at 72 hours after culture. Total, TE and ICM cell numbers were analyzed by differential staining of blastocyst. Statistical analysis was performed using t-test with SigmaPlot-2001. P-values < 0.05 were accepted as statistically significant. Results: The blastulation rate in MEM ($64.9{\pm}4.95%$) was significantly higher (p=0.0031) than that in TCM ($57.2{\pm}5.22%$). No differences were found in the number of ZiB and ZeB between MEM ($31.9{\pm}2.62$, $33.0{\pm}4.58%$), and TCM ($27.2{\pm}4.28$, $30.1{\pm}4.58%$). A total 314 blastocysts (MEM=166; TCM=148) were stained differentially. Mean cell number of blastocysts was significantly higher (p=0.0002) in TCM ($73.1{\pm}3.3$) than in MEM ($61.7{\pm}2.5$). Differential staining was successfully performed in 155 blastocysts (MEM=77; TCM=78). The percentage of ICM was significantly higher in MEM than in TCM ($20.9{\pm}1.3$ vs. $17.1{\pm}1.2%$, p=0.0281). The ICM : TE ratio was higher in TCM than in MEM (1 : $4.85{\pm}0.68$ vs. 1 : $3.78{\pm}0.78$, NS). Conclusion: These results show that MEM increase the blastocyst formation and percentage of ICM of total cells comparing with TCM in mice.

• 한국전자파학회:학술대회논문집
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• 한국전자파학회 2005년도 종합학술발표회 논문집 Vol.15 No.1
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• pp.7-12
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• 2005

A compact microstrip band-selective filter for ultra-wideband (UWB) radio system is proposed. The filter combines the traditional short-circuited stub highpass filter and coupled resonator bandstop filter on both sides of the mitered 50-ohm microstrip line. To realize the pseudo-highpass filtering characteristic over UWB frequency band (3.1 GHz to 10.6 GHz), a distributed highpass filter scheme is adopted. Three coupled resonators are utilized to obtain the band stop function at the desired frequency band. By meandering the coupled resonators, there is 29% reduction in footprint compared to the traditional bandstop filter using L-shaped resonators. The measured results show that the filter has a wide passband of 146.7 % (2.1 GHz to 10.15 GHz) with low insertion loss and the stop band of 7.42 % (5.32 GHz to 5.73 GHz) for 3-dB bandwidth. The measured group delay is less than 0.7 ns within the passband except the rejection band.

• 한국통신학회논문지
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• 제31권4B호
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• pp.344-348
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• 2006

본 논문에서는 정책기반 네트웍 관리 기법을 지원하는 셀룰라 망에서 효율적인 QoS를 제공하는 방안을 제시하였다. 제안된 정책기반은 DiffServ에 기반한 우선순위 조절기법을 사용하여 시스템 상항에 따라 각각 다른 우선순위를 할당하여 트래픽별 QoS 수준을 유지하도록 한다. ns-2 환경 시뮬레이션을 사용하여 Conversational, Streaming, Interactive and background 트래픽에 대해서 DiffServ에 기반을 둔 정책을 사용할 경우, 비실시간 트래픽이 많이 발생하더라도 실시간 트래픽의 QoS에는 크게 영향을 주지 않고도 요구된 QoS를 보장함으로써 비 실시간 트래픽에 의해 네트워크 Congestion이 발생하는 상황에도 실시간 트래픽의 QoS를 보장할 수 있다는 것을 검증하였다.

• Journal of electromagnetic engineering and science
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• 제16권1호
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• pp.7-12
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• 2016

This paper presents the design of a negative group delay circuit (NGDC) using the filter synthesis approach. The proposed design method is based on a frequency transformation from a low-pass filter (LPF) to a bandstop filter (BSF). The predefined negative group delay (NGD) can be obtained by inserting resistors into resonators. To implement a circuit with a distributed transmission line, a circuit conversion technique is employed. Both theoretical and experimental results are provided for validating of the proposed approach. For NGD bandwidth and magnitude flatness enhancements, two second-order NGDCs with slightly different center frequencies are cascaded. In the experiment, group delay of $5.9{\pm}0.5ns$ and insertion loss of $39.95{\pm}0.5dB$ are obtained in the frequency range of 1.935-2.001 GHz.

• 한국통신학회논문지
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• 제33권3B호
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• pp.123-134
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• 2008

본 논문에서는 센서 노드의 에너지 소모의 효율성을 증대시키는 무선 센서 네트워크에 대한 라우팅 알고리즘을 제안한다. 각 센서 노드는 멀티 홉 센서 필드에서 최초의 플러딩 과정을 통해 싱크 노드로의 최소 홉수를 나타내는 플러딩 레벨 값을 얻는다. 이 값은 싱크 노드로의 연결을 보장하고 클러스터를 구성하는 동안 사용되며 라우팅 과정에서 효과적으로 사용되어 에너지 효율성을 증가시킨다. 이 알고리즘은 분석과 많은 실험을 통해 성능평가가 이루어진다.

• Journal of the Optical Society of Korea
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• 제16권3호
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• pp.288-291
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• 2012

We designed an ultra-wide band-pass filter applicable to microwave reflectometry for KSTAR (Korea Superconducting Tokamak Advanced Research) and to microwave photonics. The proposed ultra-wide band-pass filter exhibits a metamaterial structure characterized by a wide band, low insertion loss, and high skirt selectivity. The proposed filter is applied to enhance the linearity of reflectometry at the output of a VCO (voltage controlled oscillator). The pass-band of the proposed filter is observed at 18~28 GHz, and the out-of-band rejection is below 20 dB. Further, we constructed an unwrapped negative phase of S(2, 1) to verify the characteristics of the metamaterial. The under- and upper-band at lower limits of the pass-band are left- and right-handed, respectively. The group delay of the filter is less than 0.5 ns.

• 대한본초학회지
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• 제37권5호
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• pp.27-35
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• 2022

Objectives : 3-Acetyl-11-keto-𝛽-boswellic acid (AKBA) is a major active compound in Boswellia serrata. We investigated the arthritic changes following AKBA administration in monosodium iodoacetate (MIA)-induced osteoarthritis rats. Methods : All rats were randomly divided into five groups: Normal, Control, INDO (indomethacin 2 mg/kg treated), AKBA30 (AKBA 30 mg/kg treated), and AKBA60 (AKBA 60 mg/kg treated); drugs were given 2 weeks before MIA injection. For all groups except the normal group, 50 µL of sterile saline with MIA (80 mg/mL) was injected into the right knee joint 2 weeks after drug administration. The drug administration was continued for 4 weeks from 1 week after osteoarthritis induction. The histomorphological changes of knee joint cartilage were observed by H&E staining. Also, the levels of glycosaminoglycan (GAG), cartilage oligomeric matrix protein (COMP), 5-lipoxygenase (5-LOX), 5-LOX-activating protein (FLAP), and leukotriene B₄ (LTB₄) in the knee joint were determined by the ELISA kits. The expressions of mitogen-activated protein kinases (MAPKs), inflammatory cytokines, and matrix metalloproteinases (MMPs) in knee joint were detected by Western blot. Results : Data show that levels of 5-LOX, FLAP, LTB4, and COMP were downregulated significantly in the AKBA treated groups when compared to those in the Control group. On the other hand, GAG levels were significantly elevated. As a result of Western blot, the AKBA-treated groups significantly inhibited phosphorylation of MAPKs. In addition, significant downregulation of the expression of inflammatory cytokines and MMPs was found in the AKBA-treated groups. Conclusion : Our findings suggest that administration of AKBA could exert better chondroprotective and anti-inflammatory effects for MIA-induced osteoarthritis rats.

• Environmental Analysis Health and Toxicology
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• 제22권2호통권57호
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• pp.137-145
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• 2007

The effect of cadmium chloride $(CdCl_2)$ on the expression of E-cadherin was examined in bEnd.3 mouse brain endothelial cells. $CdCl_2$ induced $PGE_2$ release, which were blocked by non-steroidal antinflamatory drugs (NSAIDs) such as indomethacin and NS398 indicating the expression of COX-2 might contribute to $PGE_2$ production. $CdCl_2$ decreased the expression of E-cadherin, but not VE-cadherin at levels of mRNA and protein. Reduced expression level of E-cadherin was restored by NSAIDs, which was reversed by the addition of $PGE_2$. $CdC_2$-induced decrease of E-cadherin level was also recovered by antioxidants including N-acetylcyteine (NAC) and trolox. Together with previous report which showed $CdCl_2$ induced COX-2 expression in a cellular oxidative stress dependent manner, these data suggest that $CdCl_2$ decreases E-cadherin expression through induction of cellular oxidative stress and in turn COX-2 expression in brain endothelial cells.

• 한국간담췌외과학회지
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• 제28권1호
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• pp.70-79
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• 2024

Backgrounds/Aims: After pancreatoduodenectomy (PD), an early oral diet is recommended; however, the postoperative nutritional management of PD patients is known to be highly variable, with some centers still routinely providing parenteral nutrition (PN). Some patients who receive PN experience clinically significant complications, underscoring its judicious use. Using a large cohort, this study aimed to determine the proportion of PD patients who received postoperative nutritional support (NS), describe the nature of this support, and investigate whether receiving PN correlated with adverse perioperative outcomes. Methods: Data were extracted from the Recurrence After Whipple's study, a retrospective multicenter study of PD outcomes. Results: In total, 1,323 patients (89%) had data on their postoperative NS status available. Of these, 45% received postoperative NS, which was "enteral only," "parenteral only," and "enteral and parenteral" in 44%, 35%, and 21% of cases, respectively. Body mass index < 18.5 kg/m² (p = 0.03), absence of preoperative biliary stenting (p = 0.009), and serum albumin < 36 g/L (p = 0.009) all correlated with receiving postoperative NS. Among those who did not develop a serious postoperative complication, i.e., those who had a relatively uneventful recovery, 20% received PN. Conclusions: A considerable number of patients who had an uneventful recovery received PN. PN is not without risk, and should be reserved for those who are unable to take an oral diet. PD patients should undergo pre- and postoperative assessment by nutrition professionals to ensure they are managed appropriately, and to optimize perioperative outcomes.