• Journal of Institute of Control, Robotics and Systems
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• v.11 no.3
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• pp.240-245
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• 2005

In this paper, planar waypoint guidance synthesis for UAVs using the LQ optimal impact-angle-control guidance law is proposed. We prove that the energy-optimal control problem with the constraint of passing through the waypoints is equivalent to the problem of finding the optimal pass angles on each waypoint of the optimal impact-angle-control law. The optimal pass angles can be obtained as a numerical solution of the simple pass angle optimization problem that requires neither input parameterization nor constraints. The trajectory obtained by applying the optimal impact-angle-control law with these optimal pass angles becomes energy optimal.

• Bulletin of the Korean Chemical Society
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• v.25 no.5
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• pp.711-714
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• 2004

Peroxynitrite enters erythrocytes through band 3 anion exchanger and oxidizes cytosolic proteins therein. As a protein associated with band 3, carbonic anhydrase II may suffer from peroxynitrite-induced oxidative damages. Esterase activity of carbonic anhydrase II decreased as the concentration of peroxynitrite increased. Neither hydrogen peroxide nor hypochlorite affected the enzyme activity. Inactivation of the enzyme was in parallel with the release of zinc ion, which is a component of the enzyme's active site. SDS-PAGE of peroxynitrite-treated samples showed no indication of fragmentation but non-denaturing PAGE exhibited new bands with lower positive charges. Western analysis demonstrated that nitration of tyrosine residues increased with the peroxynitrite concentration but the sites of nitration could not be determined. Instead MALDI-TOF analysis identified tryptophan-245 as a site of nitration. Such modification of tryptophan residues is responsible for the decrease in tryptophan fluorescence. These results demonstrate that peroxynitrite nitrates tyrosine and tryptophan residues of carbonic anhydrase II without causing fragmentation or dimerization. The peroxynitrite-induced inactivation of the enzyme is primarily due to the release of zinc ion in the enzyme's active site.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2002.11b
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• pp.36-37
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• 2002

율무(Coix lacryma-jobi)의 핵형 분석을 한 결과 1번 염색체는 short arm과 long arm의 크기가 같은 metacentric chromosome이었으며, 전체의 염색체에 대한 상대적인 길이가 12.8로 가장 길었다. 1번 염색체는 단완과 장완의 양쪽 터미널에 각각 하나씩의 밴드를 나타냈으며 단완과 장완 각각에 interstitial band가 나타났다. 또한 1번 염색체는 단완 끝에 부수체를 갖는 NOR 염색체임을 알 수 있었다. 2번 염색체는 Short arm에 비해 long arm이 길었으며, 전체의 염색체에 대한 상대적인 길이는 11.8로 1번 염색체 다음으로 길었다. 2번 염색체 단완 끝에 하나의 터미널 밴드와 양완의 중간에 각각 interstitial 밴드를 나타냈다. 3번 염색체는 2번 염색체 보다 short arm의 길이보다 더 짧았으며, 상대적인 길이는 10.8로 2번 염색체보다 짧았다. 3번 염색체는 단완 끝에 하나의 terminal 밴드와 centromere 밴드를 나타냈다.(중략)

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.937-942
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• 2003

Nitric oxide(NO) induces apoptosis in human osteoblasts. Treatment with exogenous NO donors, SNAP (S-Nitroso-N-acelylpenicillamine) and SNP (sodium nitroprusside), to MG-63 osteoblasts resulted in apoptotic morphological changes, as shown by a bright blue-fluorescent condensed nuclei and chromatin fragmentation by fluorescence microscope of Hoechst 33258-staining. The activities of caspase-9 and the subsequent caspase-3-like cysteine proteases were increased during NO-induced cell death. Pretreatment with Z-VAD-FMK (a pancaspase inhibitor) or Ac-DEVD-CHO (a specific caspase-3 inhibitor) abrogated the NO-induced cell death. The NO donor markedly activated JNK, a stress-activated protein kinase in the human osteoblasts. This study showed that the inhibition of the JNK pathway markedly reduced NO-induced cell death. But neither PD98059 (MEK inhibitor) nor SB203580 (p38 MAPK inhibitor) had any effect on NO-induced death. Taken together, these results suggest that JNK/SAPK may be related to NO-induced apoptosis in MG-63 human osteoblasts.

• Phonetics and Speech Sciences
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• v.9 no.3
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• pp.17-23
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• 2017

The present study investigates the effect of Accentual Phrase on F0 using a subset of large-scale corpus of Seoul Korean. Four syllable words which were neither preceded nor followed by silent pauses were presumed to be canonical exemplars of Accentual Phrases in Korean. These four syllable words were extracted from female speakers' speech samples. Growth curve analyses, combination of regression and polynomial curve fitting, were applied to the four syllable words. Four syllable words were divided into four groups depending on the categorical status of the initial segment: voiceless obstruents, voiced obstruents, sonorants, and vowels. Results of growth curve analyses indicate that initial segment types have an effect on the F0 (in semitone) in the nucleus of the initial syllable, and the cubic polynomial term revealed that some of the medial low tones in the 4 syllable words may be guided by the principle of contrast maximization, while others may be governed by the principle of ease of articulation.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.72.1-72.1
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• 2018

Recently, an analysis of 3-micron spectra of CH4 line emission from our Gemini/GNIRS observations of Jupiter's polar regions yielded an unexpected result: The homopause (~1 microbar pressure level) located directly above the long-lasting 8-micron CH4 north-polar hot spot (Great 8-micron Hot Spot: GHS) is cool compared with the temperatures of nearby auroral regions (Kim et al. 2017). Most of the 8-micron emission of the GHS originates from CH4 at the ~1 mbar level (i.e., deeper in the stratosphere, where cooling time is several years), much longer than at the altitude of the homopause. We propose a mechanism to explain the temperature difference: locally-fixed and transient, but energetic auroral particles, which can penetrate to the 1 mbar level and deposit energy there creating and maintaining the GHS. For Saturn, thus far we have not detected distinctive 8-micron nor 3-micron CH4 hot spots in the polar regions. We will present a possible implication for this difference between Jupiter and Saturn.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.3
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• pp.186-195
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• 2003

This paper deals with eigenvalue assignment techniques for linear time-varying systems as a way of achieving feedback stabilization. For this, the novel eigenvalue concepts, which are the time-varying counterparts of the conventional (time-invariant) eigenvalue notions, are introduced. Then, the Ackermann-like formulae for SISO/MIMO linear time-varying systems are proposed. It is believed that these techniques are the generalized versions of the Ackermann formulae for linear time-invariant systems. The advantages of the proposed Ackermann-like formulae are that they neither require the transformation of the original system into the phase-variable form nor compute the eigenvalues of the original system. Two examples are given to demonstrate the capabilities of the proposed techniques.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5657-5661
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• 2013

In India, among males, leukemia rates vary across the country. The present unmatched hospital-based case-control study conducted at Tata Memorial Hospital included subjects registered between the years 1997-99. There were 246 leukemia cases and 1,383 normal controls. Data on demographics, lifestyle, diet and occupation history were recorded. Cigarette (OR=2.1) and bidi smoking (OR=3.4) showed excess risk for leukemia. Odds ratios were 3.9 for fish-eaters, 0.40 for chilli eaters, 1.5 for milk drinkers and 0.60 for coffee drinkers, compared to non-drinkers/eaters. However, neither exposure to use of pesticides nor cotton dust showed any excess risk for leukemia.

• The Korean Journal of Physiology and Pharmacology
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• v.7 no.3
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• pp.181-185
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• 2003

Whether there exists a sympathetic neural regulation on the aquaporin (AQP) channels in the kidney was examined. Male Sprague-Dawley rats were used. They were renal nerve denervated by stripping the nervous and connective tissues passing along the renal artery and vein, and painting these vessels with 10% phenol solution through a midline abdominal incision. Three days later, the expression of AQP1-4 proteins in the denervated kidneys was determined. The content of norepinephrine was found significantly decreased following the denervation. Accordingly, the expression of AQP2 proteins was markedly decreased. The expression of AQP3 and AQP4 was also slightly but significantly decreased, while that of AQP1 was not. Neither the basal nor the AVP-stimulated accumulation of cAMP was significantly affected in the denervated kidney. It is suggested that the sympathetic nervous system has a tonic stimulatory effect on AQP channels in the kidney.

• Journal of Power System Engineering
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• v.18 no.3
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• pp.29-35
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• 2014

A new method is presented that uses guided wave techniques for sludge and blockage detection in long-range pipelines. Existing techniques have the limitations that the sludge position needs to be known a priori and the area to be inspected needs to be accessible. A novel guided wave technique has been developed that allow the sludge or blockages to be detected remotely without the need to access the specific location where the pipe is blocked, nor to open the pipe. The technique measures the reflection of guided waves by sludge that can be used to accurately locate the blocked region. The effectiveness of the proposed technique is demonstrated and confirmed by experimental measurements.