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우측 폐로 전이된 전이성 다형태 선종 -증례 보고- (Metastasizing Pleomorphic Adenoma in Right Lung -A case report -)

  • 정원상;남승혁;강정호;김영학;김응수;김혁
    • Journal of Chest Surgery
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    • 제40권2호
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    • pp.143-146
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    • 2007
  • 이하선에 생기는 전이성 다형태 선종은 매우 드문 질환으로서 조직학적으로는 양성이나 임상적으로는 전이를 일으키는 논쟁의 여지가 많은 병변이다. 저자들은 이하선의 다형성 선종으로 절제술을 경험한 57세 남자에게서, 4년 후에 흉막과 우측 폐, 종격동, 심낭, 늑간근의 다발성 전이를 진단하여 전이암 절제술을 경험하였기에 보고하고자 한다.

Data Alignment for Data Fusion in Wireless Multimedia Sensor Networks Based on M2M

  • Cruz, Jose Roberto Perez;Hernandez, Saul E. Pomares;Cote, Enrique Munoz De
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제6권1호
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    • pp.229-240
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    • 2012
  • Advances in MEMS and CMOS technologies have motivated the development of low cost/power sensors and wireless multimedia sensor networks (WMSN). The WMSNs were created to ubiquitously harvest multimedia content. Such networks have allowed researchers and engineers to glimpse at new Machine-to-Machine (M2M) Systems, such as remote monitoring of biosignals for telemedicine networks. These systems require the acquisition of a large number of data streams that are simultaneously generated by multiple distributed devices. This paradigm of data generation and transmission is known as event-streaming. In order to be useful to the application, the collected data requires a preprocessing called data fusion, which entails the temporal alignment task of multimedia data. A practical way to perform this task is in a centralized manner, assuming that the network nodes only function as collector entities. However, by following this scheme, a considerable amount of redundant information is transmitted to the central entity. To decrease such redundancy, data fusion must be performed in a collaborative way. In this paper, we propose a collaborative data alignment approach for event-streaming. Our approach identifies temporal relationships by translating temporal dependencies based on a timeline to causal dependencies of the media involved.

다발성 캐슬만병과 공존한 경부 악성 림프종 1례 (A Case of Cervical Malignant Lymphoma Coexisted with Multicentric Castleman's Disease)

  • 장규호;정영도;서윤태;김정규
    • 대한두경부종양학회지
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    • 제32권2호
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    • pp.35-39
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    • 2016
  • Castleman's disease (CD) is an uncommon lymphoproliferative disorder. The disease entity is classified into 2 clinical subtypes, unicentric and multicentric type. Prevalence of lymphoid malignancy in multicentric CD (MCD) is very low. In this case, we report a case of 77 years old woman who developed high fever and swelling in both side of her neck. Neck lymph node biopsy revealed plasma cell hyperplasia. Patient's symptom was subsided after treatment with Dexamethasone. Three months later, multiple lymph node enlargement was developed in abdomen and neck area again. Repeated neck lymph node biopsy confirmed diffuse large B cell lymphoma. The patient started chemotherapy.

Anti-inflammatory Activity of Sambucus Plant Bioactive Compounds against TNF-α and TRAIL as Solution to Overcome Inflammation Associated Diseases: The Insight from Bioinformatics Study

  • Putra, Wira Eka;Salma, Wa Ode;Rifa'i, Muhaimin
    • Natural Product Sciences
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    • 제25권3호
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    • pp.215-221
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    • 2019
  • Inflammation is the crucial biological process of immune system which acts as body's defense and protective response against the injuries or infection. However, the systemic inflammation devotes the adverse effects such as multiple inflammation associated diseases. One of the best ways to treat this entity is by blocking the tumor necrosis factor alpha ($TNF-{\alpha}$) and TNF-related apoptosis-inducing ligand (TRAIL) to avoid the proinflammation cytokines production. Thus, this study aims to evaluate the potency of Sambucus bioactive compounds as anti-inflammation through in silico approach. In order to assess that, molecular docking was performed to evaluate the interaction properties between the $TNF-{\alpha}$ or TRAIL with the ligands. The 2D structure of ligands were retrieved online via PubChem and the 3D protein modeling was done by using SWISS Model. The prediction results of the study showed that caffeic acid (-6.4 kcal/mol) and homovanillic acid (-6.6 kcal/mol) have the greatest binding affinity against the $TNF-{\alpha}$ and TRAIL respectively. This evidence suggests that caffeic acid and homovanillic acid may potent as anti-inflammatory agent against the inflammation associated diseases. Finally, this study needs further examination and evaluation to validate the potency of Sambucus bioactive compounds.

단일성 안와 골병변으로 확인된 갑상선 여포암의 원격 전이 1예 (A Case of Solitary Metastatic Deposit in the Orbital Rim from Follicular Thyroid Cancer)

  • 전경화;오현석;최인호;변형권
    • 대한두경부종양학회지
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    • 제37권2호
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    • pp.105-109
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    • 2021
  • Follicular thyroid carcinoma (FTC) is the second most common thyroid cancer, following papillary carcinoma. Metastasis to the orbital rim from FTC is very rare. We recently experienced a case of FTC with metastasis to the orbital rim in a 74-year-old woman, who initially presented with a huge thyroid mass and an asymptomatic solitary orbital rim lesion. The solitary orbital rim lesion was suspected to be a separate disease entity such as lymphoma from the preoperative imaging, but bone metastasis from FTC was finally confirmed after orbital rim resection and total thyroidectomy. During follow-up, the patient presented multiple bone metastasis, so the solitary orbital rim lesion was considered a clinical sign of systemic metastasis from FTC. Therefore, we present this unique case with a review of the literature.

영재와 평재의 자기조절 전략에 미치는 요인: 자율성 지지와 지적 능력에 대한 신념을 중심으로 (Factors Influencing Self-regulated Strategies: On Autonomy Support and Beliefs of Intelligence Ability of Gifted and Non-gifted Students)

  • 신민;안도희
    • 영재교육연구
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    • 제24권5호
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    • pp.877-892
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    • 2014
  • 본 연구는 고등학생의 성취 수준에 따라 세 집단(영재, 고성취 평재, 저성취 평재)으로 나누어 지각한 자율성 지지와 지적 능력에 대한 신념, 자기조절 전략 사용에 차이를 보이는지 살펴보고, 이들 변인 중 어떠한 특성이 자기조절 전략 사용에 유의미한 영향을 미치는지를 탐색하고자 하였다. 본 연구의 표집대상은 경기도 지역 영재학교 1개교, 고성취 평재와, 저성취 평재집단으로 분류한 일반 고등학교 2개교에 재학 중인 학생들을 대상으로 설문조사를 실시하여 분석하였다. 학생들의 자율성 지지, 지적 능력에 대한 신념, 자기조절 전략을 측정한 결과, 성취 수준과 또래로부터의 자율성 지지와 지적 능력에 대한 항상성 신념 및 자기조절 전략 중 부적응적 자기조절 요인을 제외한 모든 하위 요인 간 유의한 정적 상관을 보인 반면, 성취 수준과 지적 능력에 대한 항상성 신념 및 자기조절 전략 중 부적응적 자기조절 요인과는 유의미한 부적 상관을 보였다. 또한, 성취 수준에 따른 학생들의 자율성 지지, 지적 능력에 대한 신념, 자기조절 전략의 차이를 비교한 결과, 또래로부터의 자율성 지지와 지적 능력에 대한 항상성 신념을 제외한 모든 하위 변인들에서 성취 수준이 높은 영재 집단이 유의미하게 높은 것으로 나타났다. 본 연구 결과를 토대로 볼 때, 학생들에게 보다 많은 자율성 지지를 제공하고, 지적 능력에 대한 향상 가능성 신념을 높여주는 것이 더 적극적인 자기조절 전략을 사용하도록 하는 것에 도움이 될 것으로 판단된다.

단심실 -III C Solitus 형의 수술치험- (Surgical Repair of Single Ventricle (Type III C solitus))

  • naf
    • Journal of Chest Surgery
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    • 제12권3호
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    • pp.281-288
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    • 1979
  • For years, physicians and anatomists have been interested in the heart that has one functioning ventricle. Various terms have been suggested for this entity including single ventricle, common ventricle, double-inlet left ventricle, cor biatriatum triloculare, and primitive ventricle. In this report, the term "single ventricle" is utilized as suggested by Van Praagh, and is defined as that congenital cardiac anomaly in which a common or separate atrioventricular valves open into a ventricular chamber from which both great arterial trunks emerge. An outlet chamber, or infundibulum, may or may not be present and give rise to the origin of either of the great arteries. This definition excludes the entity of mitral and tricuspid atresia. An 11 year old cyanotic boy was admitted chief complaints of exertional dyspnea and frequent upper respiratory infection since 2 weeks after birth. He was diagnosed as inoperable cyanotic congenital heart disease, and remained without any corrective treatment up to his age of 11 year when he suffered from aggravation of symptoms and signs of congestive heart failure for 2 months before this admission. On 22nd of May 1979, he was admitted for total corrective operation under the impression of tricuspid atresia suggested by a pediatrician. Physical check revealed deep cyanosis with finger and toe clubbing, and grade V systolic ejection murmur with single second heart sound was audible at the left 3rd intercostal space. Development was moderate in height [135 cm] and weight[28Kg]. Routine lab findings were normal except increased hemoglobin [21.1gm%], hematocrit [64 %], and left axis deviation with left ventricular hypertrophy on EKG. Cardiac catheterization and angiography revealed 1-transposition of aorta, pulmonic valvular stenosis, double inlet of a single ventricle with d-loop, and normal atriovisceral relationship [Type III C solitus according to the classification of Van Praagh]. At operation, longitudinal incision at the outflow tract of right ventricle in between the right coronary artery and its branch [LAD from RCA] revealed high far anterior aortic valve which had fibrous continuity with mitral annulus, and pulmonic valve was stenotic up to 4 mm in diameter positioned posterolaterally to the aorta. Ventricular septum was totally defective, and one markedly hypertrophied moderator band originated from crista supraventricularis was connected down to the imaginary septum of the ventricular cavity as a pseudoseptum of the ventricle. Size of the defect was 3X3 cm2 in total. Patch closure of the defect with a Teflon felt of 3.5 x 4 cm2 was done with interrupted multiple sutures after cut off of the moderator band, which was resutured to the artificial septum after reconstruction of the ventricular septum. Pulmonic valvotomy was done from 4 mm to 11 mm in diameter thru another pulmonary arteriotomy incision, and right ventriculotomy wound was closed reconstructing the right ventricular outflow tract with pericardial autograft of 3 x 4 cm2. Atrial septal defect of 2 cm in diameter was closed with 3-0 Erdeck suture, and atrial wall was sutured also when rectal temperature reached from 24`C to 35.5`C. Complete A-V block was managed with temporary external pacemaker with a pacing rate of 110/min. thru myocardial wire, and arterial blood pressure of 80/50 mmHg was maintained with Isuprel or Dopamine dripping under the CVP of 25-cm saline. Consciousness was recovered one hour after the operation when his blood pressure reached 100 /70 mmHg, but vital signs were not stable, and bleeding from the pericardial drainage and complete anuria were persisted until his heart could not capture the pacemaker impulse, and patient died of low output syndrome 320 min after the operation.

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Ebstein 기형의 수술 -2례 보고- (Surgical Repair for Ebstein's Anomaly)

  • naf
    • Journal of Chest Surgery
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    • 제12권3호
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    • pp.289-296
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    • 1979
  • For years, physicians and anatomists have been interested in the heart that has one functioning ventricle. Various terms have been suggested for this entity including single ventricle, common ventricle, double-inlet left ventricle, cor biatriatum triloculare, and primitive ventricle. In this report, the term "single ventricle" is utilized as suggested by Van Praagh, and is defined as that congenital cardiac anomaly in which a common or separate atrioventricular valves open into a ventricular chamber from which both great arterial trunks emerge. An outlet chamber, or infundibulum, may or may not be present and give rise to the origin of either of the great arteries. This definition excludes the entity of mitral and tricuspid atresia. An 11 year old cyanotic boy was admitted chief complaints of exertional dyspnea and frequent upper respiratory infection since 2 weeks after birth. He was diagnosed as inoperable cyanotic congenital heart disease, and remained without any corrective treatment up to his age of 11 year when he suffered from aggravation of symptoms and signs of congestive heart failure for 2 months before this admission. On 22nd of May 1979, he was admitted for total corrective operation under the impression of tricuspid atresia suggested by a pediatrician. Physical check revealed deep cyanosis with finger and toe clubbing, and grade V systolic ejection murmur with single second heart sound was audible at the left 3rd intercostal space. Development was moderate in height [135 cm] and weight[28Kg]. Routine lab findings were normal except increased hemoglobin [21.1gm%], hematocrit [64 %], and left axis deviation with left ventricular hypertrophy on EKG. Cardiac catheterization and angiography revealed 1-transposition of aorta, pulmonic valvular stenosis, double inlet of a single ventricle with d-loop, and normal atriovisceral relationship [Type III C solitus according to the classification of Van Praagh]. At operation, longitudinal incision at the outflow tract of right ventricle in between the right coronary artery and its branch [LAD from RCA] revealed high far anterior aortic valve which had fibrous continuity with mitral annulus, and pulmonic valve was stenotic up to 4 mm in diameter positioned posterolaterally to the aorta. Ventricular septum was totally defective, and one markedly hypertrophied moderator band originated from crista supraventricularis was connected down to the imaginary septum of the ventricular cavity as a pseudoseptum of the ventricle. Size of the defect was 3X3 cm2 in total. Patch closure of the defect with a Teflon felt of 3.5 x 4 cm2 was done with interrupted multiple sutures after cut off of the moderator band, which was resutured to the artificial septum after reconstruction of the ventricular septum. Pulmonic valvotomy was done from 4 mm to 11 mm in diameter thru another pulmonary arteriotomy incision, and right ventriculotomy wound was closed reconstructing the right ventricular outflow tract with pericardial autograft of 3 x 4 cm2. Atrial septal defect of 2 cm in diameter was closed with 3-0 Erdeck suture, and atrial wall was sutured also when rectal temperature reached from 24`C to 35.5`C. Complete A-V block was managed with temporary external pacemaker with a pacing rate of 110/min. thru myocardial wire, and arterial blood pressure of 80/50 mmHg was maintained with Isuprel or Dopamine dripping under the CVP of 25-cm saline. Consciousness was recovered one hour after the operation when his blood pressure reached 100 /70 mmHg, but vital signs were not stable, and bleeding from the pericardial drainage and complete anuria were persisted until his heart could not capture the pacemaker impulse, and patient died of low output syndrome 320 min after the operation.

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국적외항선사의 경영실태분석과 재무구조 영향요인에 관한 실증연구 (A Study on the Financial Structure Effect Factor and Business Analysis of Ocean Shipping Companies)

  • 이성윤;김영대;안기명
    • 한국항해항만학회지
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    • 제43권4호
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    • pp.264-272
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    • 2019
  • 본 연구에서 기업가치의 대용변수로 활용된 투하자산수익률과 재무구조(부채비율)은 정(+)의 관련성을 보이고 있다. 이는 재무적 곤경에 처하기 이전에는 자기자본비용보다 절세효과가 있는 부채의 자본비용이 저렴하기 때문에 기업가치와 재무구조는 정(+)의 관련이 있다는 정태적 절충이론과 부합되는 결과이다. 또한, 영업수익성(EBITDA/매출), 투자안전성, 총자산 성장률, 순운전자본 그리고 감가상각비는 재무구조(부채비율)와 부(-)의 관련성을 띠고 있다. 이는 성장률이 낮을수록 부채비율이 높다는 Jensen의 부채의 통제가설과 수익성과 현금흐름이 높은 기업은 내부자금조달이 원활하므로 부채비율이 낮다는 자금순위이론에 부합되는 연구결과이다. 연료비, 차입금, 총자산회전율, 금융비용, 용선료, 유형자산율은 부채비율과 유의적인 정(+)의 관련성을 띠고 있다. 이는 대리이론과 부합되는 결과이며 파산한 H선사처럼 과도한 용선료가 우리나라 외항선사의 재무구조를 압박하는 요인으로 확인하였다.

흉부손상에 의한 외상성 가사 4예 (Traumatic Asphyxia with Compressive Thoracic Injuries -4 Cases Report-)

  • 김현순
    • Journal of Chest Surgery
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    • 제13권3호
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    • pp.212-218
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    • 1980
  • A severe crushing injury of the chest produce a very striking syndrome referred to as traumatic asphyxia. This syndrome is characterized by bluish-red discoloration of the skin which is limited to the distribution of the valveless veins of the head and neck. And also if it is characterized by bilateral subconjunctival hemorrhages and neurological manifestations. But these clinical entities faded away progressively in a few weeks. Apporximately 90% of the patients who live for more than a few hours will recover from traumatic asphyxia when it occurs as a single entity. And so, death results from either severe associated injuries of from subsequent infection, rather than from pulmonary or cardiac insufficiency in traumatic asphyxia. We have experienced 4 cases of traumatic asphyxia with severe crushing thoracic injuries at department of the chest surgery, Captial Armed forces General Hospital during about 3 years from April 1977 to Aug. 1980. The 1st 22 year-old male was struct 2$\frac{1}{2}$ ton truck on the road and was transferred to this hospital immediately. He had taken tracheostomy due to severe dyspnea with contusion pneumonia and for removal of a large amount of bronchial secretion. The 2nd case was 23 year-old male who was got buried in a chasm. In this case, the heavy metal post tumbled over him back while at work. The 3rd case was 39 year-old male who leapt out of a window in 5th story while fire broke out in living room by oil stove heating. He had multiple rib fracture with right hemothor x and right colle's fracture and pelvic bone fracture. The last 22 year-old male was run over by a gun carriage. The wheel of this gun carriage passed over his thorax and right chin. He was brought to this hospital by helicopter. when he was first examined at emergency room, he was in semicomatose state and has pneurmomediastinum with multiple rib fracture and severe subcutaneous emphysema. As soon as he arrived, bilateral closed thoracostomy was performed and cardiopulmonary resuscitation was done. In hospital 8th weeks, chest series showed fibrothorax in right side even if chest wall stabilized. All 4 cases had multiple petechiae over their facees and chest and bilateral subconjunctival hemorrhages referred to as traumatic asphyxia. 3 cases except one case who received splenectomy, had been suffered from contusion pneumonia and had been treated with respiratory care. In these 3 cases, they had warning of impending injury before accident, and took a deep breath hold it and braces himself. And also, even if he had not impending fear in remaining one case, he had taken a deep breath and had got valsalva maneuver for pulling off the heavy metal post. Intrathoracic pressure rose suddenly and resulted to traumatic asphyxia in this situation. All these cases were recovered completely without sequelae except one fibrothorax, right.

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