Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Cervical Malignant Lymphoma Coexisted with Multicentric Castleman's Disease

다발성 캐슬만병과 공존한 경부 악성 림프종 1례

  • Jang, Gyu Ho (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Jung, Young Do (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Seo, Youn Tae (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu) ;
  • Kim, Jeong Kyu (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu)
  • 장규호 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 정영도 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 서윤태 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김정규 (대구가톨릭대학교 의과대학 이비인후과학교실)
  • Received : 2016.08.29
  • Accepted : 2016.10.26
  • Published : 2016.11.30
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Abstract

Castleman's disease (CD) is an uncommon lymphoproliferative disorder. The disease entity is classified into 2 clinical subtypes, unicentric and multicentric type. Prevalence of lymphoid malignancy in multicentric CD (MCD) is very low. In this case, we report a case of 77 years old woman who developed high fever and swelling in both side of her neck. Neck lymph node biopsy revealed plasma cell hyperplasia. Patient's symptom was subsided after treatment with Dexamethasone. Three months later, multiple lymph node enlargement was developed in abdomen and neck area again. Repeated neck lymph node biopsy confirmed diffuse large B cell lymphoma. The patient started chemotherapy.

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