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Pain, Acupuncture and Brain Imaging (통증, 침술 및 뇌영상)

  • Kwak, Yong-Ho;Won, Ran;Lee, Hye-Jung;Lee, Bae-Hwan
    • Science of Emotion and Sensibility
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    • v.13 no.3
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    • pp.551-558
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    • 2010
  • Pain is very complex and multi-level experience that should be objective or subjective. Acupuncture is a traditional method to heal the pain and have been based on meridian theory. There have been many clinical evidences showing the pain-relieving effect of acupuncture but science-based understanding of it was poor. Furthermore in daily life, we feel huge gap between the source of pain and pain control by acupuncture stimulation. However, the underlying connection between pain control and acupuncture stimulation has been reported in many recent reports. In this paper, we briefly introduce the brain imaging techniques (functional magnetic resonance images, positron emission tomography, electroencephalograph, and magnetoencephalography) and review researches in pain and acupuncture. Through this, the brain areas that activated by pain and acupuncture will be verified, and compared each other regarding their specificity and similarity. In addition, detailed understanding of brain function which is related to pain and acupuncture analgesia through brain imaging techniques will be discussed.

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Observation on the Shoreline Changes Using Digital Aerial Imagery for Bangamoeri Beaches (디지털항공영상을 활용한 방아머리 해빈의 해안선 변화 관측)

  • Yun, Kong-Hyun;Song, Yeong Sun
    • Korean Journal of Remote Sensing
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    • v.33 no.6_1
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    • pp.971-980
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    • 2017
  • In this research, it was presented that the strategic approach for the long-term shoreline changes using historic digital aerial images can be effective for the analysis on the bangameori beach, west coast of South Korea. For this purpose, we collected several historic digital aerial images over 9 years in the research filed and conducted GPS-VRS surveying for GCP (Ground Control Point) acquisition. Also we collected existing two dimensional shoreline digital map which was published by KHOA (Korea Hydrographic and Oceanographic Agency) in the year 2013. With these multi data sets, we provided quantitative analysis on coastal erosion using the long-term shoreline changes in the beach. Also, As the results it was found that 2m sea level was retreated in the research period with maximum 0.31m length.

A Study on Evaluation and Prioritization Process of Wastewater Reuse Alternative in Watershed Level (유역차원의 하수처리수 재이용 대안평가와 우선순위 결정과정에 관한 연구)

  • Chung, Eun-Sung;Jun, Sang-Mook;Lee, Jin Hee;Ahn, Jong Ho
    • Journal of Korean Society on Water Environment
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    • v.29 no.2
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    • pp.259-269
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    • 2013
  • This study aims to show the feasibility of wastewater reuse through hydrological analysis and propose a framework for planning using multi-criteria decision making technique. Ten alternatives of wastewater reuse (BOD: 3.0 mg/L & 4.7 mg/L) and two references in the urban watershed were considered and analyzed by using Hydrological Simulation Program in Fortran (HSPF). Though wastewater reuse has a positive effect on water quantity, it may degrade the water quality due to the high discharge concentration. This study showed that wastewater reuse can be a great alternative for the rehabilitation of distorted water cycle, if the quality is improved up to the natural streamflow and the quantity is increased up to the instreamflow requirement. In addition, to determine the project priority, three criteria were compared: 1) impacts on water quantity and water quality, respectively, 2) consideration of present hydrologic vulnerabilities on water quantity and quality and not, and 3) social and economic considerations and not. From the performance values to all criteria, the specific ranking can be derived and the feasibility of each wastewater reuse project can be checked with the comparison of the existing facilities. As a result, DJ and DR were derived to become effective in any evaluation conditions while SS and WG were improper alternatives if various criteria were considered. The decision making for project prioritization must be careful with the consideration of various impacts of wastewater reuse because the evaluation of wastewater reuse alternative showed very different priorities for each criteria.

The Ground Checkout Test of OSMI(Ocean Scanning Multispectral Imager) on KOMPSAT-1

  • Yong, Sang-Soon;Shim, Hyung-Sik;Heo, Haeng-Pal;Cho, Young-Min;Oh, Kyoung-Hwan;Woo, Sun-Hee;Paik, Hong-Yul
    • Proceedings of the KSRS Conference
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    • 1999.11a
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    • pp.375-380
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    • 1999
  • Ocean Scanning Multispectral Imager (OSMI) is a payload on the KOMPSAT satellite to perform worldwide ocean color monitoring for the study of biological oceanography. The instrument images the ocean surface using a wisk-broom motion with a swath width of 800 km and a ground sample distance (GSD) of<1km over the entire field of view (FOV). The instrument is designed to have an on-orbit operation duty cycle of 20% over the mission lifetime of 3 years with the functions of programmable gain/offset and on-board image data compression/storage. The instrument also performs sun and dark calibration for on-board instrument calibration. The OSMI instrument is a multi-spectral imager covering the spectral range from 400nm to 900nm using CCD Focal Plane Array (FPA). The ocean colors are monitored using 6 spectral channels that can be selected via ground commands. KOMPSAT satellite with OSMI was integrated and the satellite level environment tests and instrument aliveness/functional test as well, such as launch environment, on-orbit environment (Thermal/vacuum) and EMl/EMC test were performed at KARI. Test results met the requirements and the OSMI data were collected and analyzed during each test phase. The instrument is launched on the KOMPSAT satellite in the late 1999 and the image is scheduled to start collecting ocean color data in the early 2000 upon completion of on-orbit instrument checkout.

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A Community-Based Integrated Preventive Program of Depression and Its Effectiveness in Caring for Vulnerable Elderly (취약계층 노인의 우울예방을 위한 지역사회기반의 통합프로그램 개발 및 효과검증)

  • Ahn, Yang-Heui
    • Research in Community and Public Health Nursing
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    • v.14 no.2
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    • pp.287-298
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    • 2003
  • The purpose of the study was to develop an integrated prevention program to strengthen elders self-care capability and to examine its effectiveness on their psychological condition. This study used one group pre- and post-test design. Subjects were 85 elderly residents (over 65 years of age) who lived alone, and received free basic medical care and social welfare services in a rural community in Korea. Subject eligibility criteria for this study were to an elders who 1) is not currently taking any anti-depressant medication 2) is able to communicate, and 3) agrees to participate in this study. The integrated program was composed of horticulture, reminiscence, and friendship activities. Twelve sessions were provided for 12 weeks in community-based partnerships to achieve better outcomes. The intervention was case-managed by a public health nurse and aided by six volunteers. The main outcome variable was depression, which was assessed by using 15 items selected from the Geriatric Depression Scale-short form Korean version. Socio-demographic characteristics, functional status, and satisfaction with social support were used as covariates. Results showed that there was a significant intervention effect at post-intervention time point compared to pre-intervention time point(E.S. 0.94). Multiple linear regression analysis showed significant interaction effects between intervention and satisfaction with social support. These findings must be interpreted within the context that an effects of an integrated program could be more synergistically increased when social support factor is considered in the program. A community-based integrated prevention program of depression is effective for vulnerable rural elderly. It is suggested that randomized controlled trials within community setting for better methodological strength as well as multi-level outcomes on community need to be conducted in future.

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Inductorless 8.9 mW 25 Gb/s 1:4 DEMUX and 4 mW 13 Gb/s 4:1 MUX in 90 nm CMOS

  • Sekiguchi, Takayuki;Amakawa, Shuhei;Ishihara, Noboru;Masu, Kazuya
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.10 no.3
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    • pp.176- 184
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    • 2010
  • A low-power inductorless 1:4 DEMUX and a 4:1 MUX for a 90 nm CMOS are presented. The DEMUX can be operated at a speed of 25 Gb/s with the power supply voltage of 1.05 V, and the power consumption is 8.9 mW. The area of the DEMUX core is $29\;{\times}\;40\;{\mu}m^2$. The operation speed of the 4:1 MUX is 13 Gb/s at a power supply voltage of 1.2 V, and the power consumption is 4 mW. The area of the MUX core is $30\;{\times}\;18\;{\mu}m^2$. The MUX/DEMUX mainly consists of differential pseudo-NMOS. In these MUX/DEMUX circuits, logic swing is nearly rail-to-rail, and a low $V_{dd}$. The component circuit is more scalable than a CML circuit, which is commonly used in a high-performance MUX/DEMUX. These MUX/DEMUX circuits are compatible with conventional CMOS logic circuit, and it can be directly connected to CMOS logic gates without logic level conversion. Furthermore, the circuits are useful for core-to-core interconnection in the system LSI or chip-to-chip communication within a multi-chip module, because of its low power, small footprint, and reasonable operation speed.

Regulation of the Gene Encoding Glutathione Synthetase from the Fission Yeast

  • Kim, Su-Jung;Shin, Youn-Hee;Kim, Kyung-Hoon;Park, Eun-Hee;Sa, Jae-Hoon;Lim, Chang-Jin
    • BMB Reports
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    • v.36 no.3
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    • pp.326-331
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    • 2003
  • The fission yeast cells that contained the cloned glutathione synthetase (GS) gene showed 1.4-fold higher glutathione (GSB) content and 1.9-fold higher GS activity than the cells without the cloned GS gene. Interestingly, $\gamma$-glutamylcysteine synthetase activity increased 2.1-fold in the S. pombe cells that contained the cloned GS gene. The S. pombe cells that harbored the multi copy-number plasmid pRGS49 (containing the cloned GS gene) showed a higher level of survival on solid media with cadmium chloride (1 mM) or mercuric chloride ($10\;{\mu}M$) than the cells that harbored the YEp357R vector. The 506 bp upstream sequence from the translational initiation point and N-terminal8 amino acid-coding region were fused into the promoteriess $\beta$-galactosidase gene of the shuttle vector YEp367R to generate the fusion plasmid pUGS39. Synthesis of $\beta$-galactosidase from the fusion plasmid pUGS39 was significantly enhanced by cadmium chloride and NO-generating S-nitroso-N-acetylpenicillamine (SNAP) and sodium nitroprusside (SN). It was also induced by L-buthionine-(S,R)-sulfoximine, a specific inhibitor of $\gamma$-glutamylcysteine synthetase (GCS). We also found that the expression of the S. pombe GS gene is regulated by the Atf1-Spc1-Wis1 signal pathway.

A Study on ILD(Interlayer Dielectric) Planarization of Wafer by DHF (DHF를 적용한 웨이퍼의 층간 절연막 평탄화에 관한 연구)

  • Kim, Do-Youne;Kim, Hyoung-Jae;Jeong, Hae-Do;Lee, Eun-Sang
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.5
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    • pp.149-158
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    • 2002
  • Recently, the minimum line width shows a tendency to decrease and the multi-level increases in semiconductor. Therefore, a planarization technique is needed and chemical mechanical polishing(CMP) is considered as one of the most suitable process. CMP accomplishes a high polishing performance and a global planarization of high quality. However there are several defects in CMF, such as micro-scratches, abrasive contaminations and non-uniformity of polished wafer edges. Wet etching process including spin-etching can eliminate the defects of CMP. It uses abrasive-free chemical solution instead of slurry. On this study, ILD(Interlayer-Dielectric) was removed by CMP and wet etching process using DHF(Diluted HF) in order to investigate the possibility of planrization by wet etching mechanism. In the thin film wafer, the results were evaluated from the viewpoint of material removal rate(MRR) and within wafer non-uniformity(WIWNU). And the pattern step heights were also compared for the purpose of planarity characterization of the patterned wafer. Moreover, Chemical polishing process which is the wet etching process with mechanical energy was introduced and evaluated for examining the characteristics of planarization.

Critical Review on Carcinogenicity of Metalworking Fluids (절삭유(Metalworking Fluids)의 발암성에 대한 고찰)

  • 박동욱;윤충식;이송권
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.1
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    • pp.50-62
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    • 2003
  • Exposure to metalworking fluids (MWFs) has significantly been associated with cancer developed in multi-organs, respiratory diseases and skin diseases. Several carcinogens to humans or animals are contained in MWFs. They have been reported to be mineral oils, polynuclear aromatic hydrocarbons (PAHs), formaldehyde and N-nitrosodiethanolamine (NDELA). The great hazards of MWF have forced the advanced country including United States to regulate carcinogens contained in MWF. In 2001, American Conference of Governmental Industrial Hygienists (ACGIHs) regarded MWF mist as suspected carcinogen to human (A2) and added it to “Notice of Intended Change (NIC)” list of 2001. In spite of the fact that much MWF has widely been used in many industries using machines, Korea has no legal actions for management of MWF. What is worse, even toxicity such as Carcinogenicity has not been reported. KS (Korean Standards) lists 7 advices of MWF but it does net state the hazards to health. It is very hard to control or minimize worker's exposure to MWF containing many carcinogens. Prier to the introduction of MWF to workplace, it is the most effective measure to regulate carcinogens below a certain level. Regulation on the content of PAH seems to be necessary because less amount of PAH in mineral oils improves the quality of MWF. Also, addition of nitrosating groups to MWF should be prohibited to minimize worker's exposure to NDELA. Employers and manufacturers should indicate the Carcinogenicity of all carcinogens in MWFs in Material Safety Data Sheets (MSDS) in order fer workers to recognize Carcinogenicity. Legal actions have to be taken to protect workers from health hazards due to exposure to MWF by further investigation on MWF.

A New Mobile Content Adaptation Based on Content Provider-Specified Web Clipping (컨텐츠 제공자 지정 웹 클리핑 방식의 이동 인터넷 컨텐츠 변환)

  • Yang, Seo-Min;Lee, Hyuk-Joon
    • The KIPS Transactions:PartB
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    • v.11B no.1
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    • pp.35-44
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    • 2004
  • Web contents created for desktop screens give rise to problems when they are to be displayed on the small screens of mobile terminals. While in some cases some of the objects of a page may not be displayable due to the lack of browser capability, the entire page may not be displayable due to the incompatibility with the browser in other cases. In this paper, we introduce a new mobile content adaptation approach based on web clipping, which transforms an original page into one that is optimally displayed on a mobile terminal. In this method, a source page is automatically clipped and transformed according to the clip specification made by the content provider using a clip editing tool. The clip editing tool allows the user to specify group clips, multi-level cups and dynamic clips as well as simple clips, and the presentation layout through a graphic user interface. Based on the clip specifications, each clip is transformed into an intermediate meta-language document, which in turn is transformed into a presentation page in the target markup language. Transcoding of image objects in major image file formats is also supported.