• 한국해양학회지
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• v.12 no.1
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• pp.7-12
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• 1977

Vertical mixing in the ocean affects the formation of water masses as well as the vertical distribution of nutrients and dissolved substances. this study is to investigate the effect of stability on the intensity of vertical transfer in the case of shallow and straitfied channel. It is found that the relation of the stability and vertical turbulent diffusion is given by K$\sub$z/ = -${\beta}$-(c+${\beta}$) / ${\alpha}$(E-1/${\alpha}$) where K$\sub$z/ and E denotes the vertical turbulent diffusion coefficient and stability, respectively. The empirical coefficients ${\alpha}$, ${\beta}$ and c depend on the magnitude of vertical components and stability, i.e., through thermocline intensity. The study indicates that the diffusivity of the surface mixed layer is (K$\sub$z/)=300∼1,200$\textrm{cm}^2$/sec, the thermocline layer is (K$\sub$z/)= 50∼200$\textrm{cm}^2$/sec and the cold layer is (K$\sub$z/)=200∼600$\textrm{cm}^2$/sec based on near- minimum least-squares error estimates from the regression analysis. An important result of our study comes out that the model is in accordance with the general trends of the effect of stability on the vertical turbulent diffusion coefficients in the case of shallow and strongly stratified channel.

• The Journal of Information Systems
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• v.29 no.1
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• pp.267-287
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• 2020

Purpose Online platform companies can increase the spread of content by communicating with users who have diverse preferences through social networks. Previous studies show the mixed effect on the network overlap, and there was a limited examinations for the underlying mechanism. This study expects high academic and practical implications that can be provided by studying on the user's viewership network. The purpose of this research is to examine the effects of network overlap on the users' viewership for creators of user-generated content in YouTube. We explain the direct and in-direct effects through the content sharing and the valence of user ratings. Design/methodology/approach The data contains 45 channels and 4,085 video clips from YouTube. We control the effect of the categories, channel characteristics, and vide clip characteristics on the viewership. PROCESS macro were used to analyze the direct and in-direct effects of network overlap. Findings The analysis results showed that the network overlap directly affect on the users' viewership. The variable decreases the moderators (i.e., content sharing and the valence of user ratings). This result implies that the users can not satisfy their need for uniqueness which is achieved by content sharing and rating in the overlapped network.

• Journal of the Korean housing association
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• v.22 no.3
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• pp.25-33
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• 2011

Recently, concerns about conserving proper size of urban green spaces and accessibility are increasing, regarding it as a solution to diverse urban environmental problems including pollution, ecosystem deterioration, urban climate change. Artificial ground greening such as green roofs is regarded as the only alternative that can conserve green spaces which are impossible to be secured on the ground. However, green roofs are not popularized yet and levels are very low in provincial cities despite of related technology development and support systems of related agencies. Based on the background, this study tries to present a theoretical basis of methods for green roofs, conducting green roof simulations Finally, it aims to offer base data which help establish policy direction for activation of green roof technology. As a result of a simulation for verifying temperature reduction effect, it was possible to affirm effect of a plot that green roofs applied. Especially, it was revealed that a green roof method using ground covers such as mixed planting was the most effective way to reduce temperature. Based on precise analysis of the users, actual study for activation of green roofs should be developed in the future, by presenting a standard model for experiments and obtaining information about examples of green roofs on private houses.

• 대한공업교육학회지
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• v.39 no.2
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• pp.122-143
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• 2014

The purpose of this research were to develop program of elementary school technology education using history of technology and to learn about its effect. In order to accomplish the purpose of the research, we developed the program by referring to various records and perform the qualitative experiment study through several questionnaire, pictures and materials, to learn about the program effect. The research took the mixed-model design, consisted of collection of quantitative data by Likert scale and collection of qualitative data including the open-ended questions. And the research results were as below. First, development of elementary school technology education program using history of technology was developed as program for 12 hours, 12 themes, for the elementary levels. Second, seeing the result of program of elementary school technology education using history of technology, the program for history of technology for the primary school students, a majority of answers showed high satisfaction about the program, giving answers such as 'I want to do it again following hands on minds on activity.' Third, according to the analysis on the qualitiative evidence of the program, students were found to take pictures with hands on minds on activity camera obscura with much interest and curiosity. Many students are seen to complete the task on their own with a great a look of self-satisfaction, understanding the principle of camera.

• Journal of the Korean GEO-environmental Society
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• v.13 no.6
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• pp.83-90
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• 2012

Generally, the effect of the cement deep mixing method on the improvement of clay ground is far greater than the effect of physical improvement. Although it leads to great improvement strength in the initial stage, there are not many constructional precedents in Korea and it is hard to manage quality according to the cement-clay mixing method. In order to figure out the strength characteristics according to the mixing ratio of cement, sand, and clay and the improvement characteristics of weak ground according to the forms of the specimens to be improved, marine clay was used in this study to conduct the uniaxial compression test and soil bin model test. The test piece specimens for the uniaxial compression test were mixed with sand in a fixed ratio with the criterion of the water cement ratio. The cement was mixed with clay in the ratios of 10%, 20%, 30%, and 40% to the clay weight. The moisture content of the soil ground was made in the ratios of 40%, 60%, and 80%. The test piece specimens went through curing by moistening for 7, 14, and 28 days and underwent the uniaxial compression test according to the curing period. For the bearing test, the soil bin models were made and the ground improved in the Mat type was formed. After that, the bearing strength was compared in this study according to the improvement ratio and analyzed the intervening effect between the walls of the improved specimens.

• International Journal of Highway Engineering
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• v.20 no.2
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• pp.75-85
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• 2018

PURPOSES : This study aimed to analyze traffic accidents at circular intersections, and discuss accident reduction strategies based on land use and vehicle type. METHODS : Traffic accident data from 2010 to 2014 were collected from the "traffic accident analysis system" (TAAS) data set of the Road Traffic Authority. To develop the accident rate model, a multiple linear regression model was used. Explanatory variables such as geometry and traffic volume were used to develop the models. RESULTS : The main results of the study are as follows. First, it was found that the null hypotheses that land use and vehicle type do not affect the accident rate should be rejected. Second, 16 accident rate models, which are statistically significant (with high $R^2$ values), were developed. Finally, the area of the central island, number of speed humps, entry lane width, circulatory roadway width, bus stops, and pedestrian crossings were analyzed to determine their effect on accidents according to the type of land use and vehicle. CONCLUSIONS : Through the developed accident rate models, it was revealed that the accident factors at circular intersections changed depending on land use and vehicle type. Thus, selecting the appropriate location of bus stops for trucks, widening entry lanes for cars, and installing splitter islands and optimal lighting for motorcycles were determined to be important for reducing the accident rate. Additionally, the evaluation showed that commercial and mixed land use had a weaker effect on accidents than residential land use.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.39 no.1
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• pp.49-57
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• 2002

Including RF Package inductance, substrate coupling through conductive silicon(Si)-substrate is modeled and quantitatively characterized. 2-port substrate coupling model is extended for the characterization of multi-port substrate coupling between digital circuit block and analog/RF circuit block. Furthermore, scalable parameter extraction model is developed. Multi-port substrate coupling can be investigated by linearly superposing a frequency-dependent 2-port substrate coupling model using scalable parameters. In addition, Substrate coupling including RF package inductance effect is quantitatively investigated. It is shown that package effect increases substrate coupling and shifts a characteristic frequencies(i.e., poles) to the higher frequency range. The proposed methodology can be efficiently used to the mixed-signal circuit performance verification.

• Journal of the Korean Society of Radiology
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• v.16 no.6
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• pp.799-805
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• 2022

Radiation therapy of human tissues, including bone tissue, is accompanied by side effects on normal tissues. It has a more lethal effect on stem cells, which play an essential role in tissue regeneration, including the basal cells constituting the tissue. In this study, the mouse parietal model, which implemented an artificial osteoradionecrosis model on the parietal region of the mouse, was artificially defected and then the bone regeneration was tested. In order to overcome the implemented osteoradionecrosis, a fibrin scaffold, widely used as a biomaterial, and stromal cell-derived factor-1 (SDF-1), which is used as a long-term treatment for damaged, were mixed to verify the osteoradionecrosis regeneration effect on the parietal of mouse. In order to expect a synergistic effect in the fibrin scaffolds, a fibrin scaffolds was prepared after maintaining the concentration of SDF-1 (1 ㎍/ml) in the fibrinogen solution. In this study, after artificially creating a osteoradionecrosis model in the parietal region of mouse, fibrin scaffolds were incorporated to analyze the effect of bone regeneration within 4 weeks, the initial stage of bone regeneration. In conclusion, the combined use of these two substances did not show a dramatic regenerative effect in inducing the regeneration of osteoradionecrosis in the parietal region of mouse. However, positive results were obtained that can be maintain the bone regeneration effect environment at the initial stage. Therefore, the combined use of the fibrin scaffold and SDF-1 is considered to be a suitable candidate for the effect of overcoming osteoradionecrosis.

• Korean Journal of Clinical Pharmacy
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• v.28 no.1
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• pp.24-29
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• 2018

Background: Cyclosporine is an immunosuppressive agent used to treat and prevent graft versus host reaction (GVHR)-a complication associated with stem cell transplantation. This study aimed to develop a population pharmacokinetic model of cyclosporine and investigate factors affecting cyclosporine clearance in pediatric hematopoietic stem cell transplant patients. Methods: A total of 650 cyclosporine concentrations recorded in 65 patients who underwent hematopoietic stem cell transplantation were used. Data including age, sex, weight, height, body surface area (BSA), type of disease, chemotherapy before stem cell transplantation, type of donor, serum creatinine levels, total bilirubin concentration, hematocrit value, and type of concomitant anti-fungal agents and methylprednisolone used were retrospectively collected. Data related to cyclosporine dosage, administration time, and blood concentration were also collected. All data were analyzed using the non-linear mixed effect model; a two-compartment model with first-order elimination was used. Results: The population pharmacokinetic model of cyclosporine using the NONMEM program was as follows: $CL(L/h)=5.9{\times}(BSA/1.2)^{0.9}$, V2 (L) = 54.5, Q (L/h) = 3.5, V3 (L) = 1080.0, $k_a(h^{-1})=0.000377$. BSA was selected as a covariate of cyclosporine clearance, which increased with an increase in BSA. Conclusion: A population pharmacokinetic model for Korean pediatric hematopoietic stem cell transplant patients was developed, and the important factor affecting cyclosporine clearance was found to be BSA. The model might contribute to the development of the most appropriate dosing regimen for cyclosporine. Further studies on population pharmacokinetics should be carried out, prospectively targeting pediatric patients.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.1401-1406
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• 2004

In this paper, we present the theoretical and numerical results of scavenge characteristics in a small prechamber of an HCCI(Homogeneous Charge Compression Ignition) engine. Two theoretical models are proposed in prediction of the scavenge time and the efficiency ; one is the non-mixing models in which it is assumed that the input gas($CH_{4}$) and the existing gas(air) do not mix with each other, and the other is the fully-mixed model in which the two gases are assumed to mix completely before ejecting to the ambient air. Focus is also given to the effect on the scavenge performance of the size of the chamber oulet.