• Research in Community and Public Health Nursing
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• v.30 no.2
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• pp.119-129
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• 2019

Purpose: The purpose of this study is to develop and evaluate the effects of a multifaceted cognitive training program on cognitive function, depression, and instrumental activities of daily living (IADL) in community dwelling elders with mild cognitive impairment. Methods: A non-equivalent control group pretest-posttest design was used. The subjects were recruited from a community health center in D metropolitan city and were assigned to the experimental or control group. Weekly 50-minute session intervention was delivered to the experimental group over 12 weeks. 8 weeks and 12weeks after intervention, the changes in cognitive function, depression, and IADL in the groups were measured and compared. Data were analyzed with Mann-Whitney U test, Wilcoxon Signed Rank test, and post-hoc test with Bonferroni correction using SPSS/WIN 23.0. Results: When compared with their counterparts (n=15), the elders in the experimental group (n=12) showed significant improvement in cognitive function and depression at week 12. The mean scores of IADL at week 12 were not significantly different between the groups. Conclusion: The results indicate that this multifaceted cognitive training program is effective in improving cognitive function, depression, and avoiding deterioration of IADL among elders with mild cognitive impairment.

• Biomolecules & Therapeutics
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• v.24 no.3
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• pp.291-297
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• 2016

Cytisine (CYT), a partial agonist of ${\alpha}4{\beta}2-nicotinic$ receptors, has been used for antidepressant efficacy in several tests. Nicotinic receptors have been shown to be closely associated with depression. However, little is known about the effects of CYT on the depression. In the present study, a mouse model of depression, the unpredictable chronic mild stress (UCMS), was used to evaluate the activities of CYT. UCMS caused significant depression-like behaviors, as shown by the decrease of total distances in open field test, and the prolonged duration of immobility in tail suspension test and forced swimming test. Treatment with CYT for two weeks notably relieved the depression-like behaviors in the UCMS mice. Next, proteins related to depressive disorder in the brain region of hippocampus and amygdala were analyzed to elucidate the underlying mechanisms of CYT. CYT significantly reversed the decreases of 5-HT1A, BDNF, and mTOR levels in the hippocampus and amygdala. These results imply that CYT may act as a potential anti-depressant in the animals under chronic stress.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.12 no.1
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• pp.58-65
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• 2005

Purpose: To investigate the level of depression and self management behavior in patients with diabetes. Method: From May to August 2004, 124 diabetic patients 18 years or older were surveyed using the Korean version of the BDI, the self-management scale by Toobert(2000) and hospital lab data for HbAl, FBS and Blood Sugar-2hr. Results: 1. Mean score on the BDI for the patients was 10.85 points. The score on the BDI was significantly higher in hyperglycemic patients than in normoglycemic patients. 2. The level of self management for the past week showed care on an average of 4.2 days. According to level of depression, patients in the normal group and patients in the mild group had significantly higher levels of self management than those in the moderate group. 3. According to level of depression, patients in the normal group had significantly lower levels of blood glucose than those in the moderate group, and for HbAlc and FBS those in the mild group had lower levels compared to those in the moderate group. 4. The factors significantly associated with level of self management were depression (25.66%) and duration of illness. Conclusion: Programs should be developed to combat depression in patients with diabetes in order to increase compliance through self care management and thus increase of blood glucose levels.

• Journal of agricultural medicine and community health
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• v.48 no.2
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• pp.91-102
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• 2023

Objective: This study aimed to evaluate the effects of a digital group reminiscence program on elderly patients with mild dementia who were registered with Day Care Centers. Methods: The study was conducted with elderly patients with mild dementia in Day Care Centers in D city. The patients were randomly assigned to either the experimental group or the control group and were assessed for cognitive function, depression, and ego integrity using pre-test and post-test designs. A digital group reminiscence program was applied to the experimental group. Data was collected from July 5 to September 17, 2021, using questionnaires in three sessions. Results: The pre-test cognitive function score was 12.00 in the experimental group and 11.09 in the control group. The post-test cognitive function score was 19.20 in the experimental group and 14.42 in the control group. The later cognitive function score was 18.00 in the experimental group and 13.31 in the control group. The pre-test depression score was 8.32 in the experimental group and 9.91 in the control group. The post-test depression score was 6.05 in the experimental group and 8.82 in the control group. The later depression score was 6.94 in the experimental group and 9.02 in the control group. The pre-test ego integrity score was 41.39 in the experimental group and 39.55 in the control group. The post-test ego integrity score was 57.95 in the experimental group and 51.41 in the control group. The later ego integrity score was 55.88 in the experimental group and 42.15 in the control group. Cognitive function, depression, and ego integrity showed significant differences according to group (p<.05), time (p<.001), and interaction between group and time (p<.01). Conclusion: The digital group reminiscence program was found to be effective in improving cognitive function and ego integrity and reducing depression in elderly patients with mild dementia. Further research is needed to explore the effects of repetitive digital group recall programs based on the progress, course, age, and communication level of dementia.

• Research in Community and Public Health Nursing
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• v.26 no.1
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• pp.1-10
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• 2015

Purpose: This study was conducted to investigate changes in cognitive functions, depression and life-satisfaction for elderly participants with mild cognitive impairments participating in an individual cognitive improvement program. Methods: A quasi-experimental with non-equivalent control group pretest-posttest design was implemented. The participants were senior citizens over 65 years of age who had been clinically diagnosed with mild cognitive impairments in G City and J Province (experimental group: 29, control group: 27). The experimental group participated in the individual cognitive improvement program based on Korean traditional tales and games for nine weeks. Results: After the intervention, only the participants in the experimental group reported significant improvement in K-MMSE (t=-2.5, p=.016), MoCA-K (t=-2.6, p=.008), depression (t=3.51, p=.001), and life satisfaction (t=-2.75, p=.008) when compared to those in the control group. Conclusion: These results indicated that the individual cognitive improvement program was effective in improving cognitive functions, depression, and life-satisfaction among the elderly with mild cognitive impairments. Therefore, the application of this individual cognitive improvement program developed in this study by visiting nurses may strengthen the cognitive functions of seniors with mild cognitive impairments.

• International Journal of Advanced Culture Technology
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• v.9 no.4
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• pp.29-39
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• 2021

Cognitive behavioral therapy (CBT) is effective for people with an addiction tendency. This study aims to implement a CBT program for college students at high risk of smartphone addiction and investigate the impact of the program on their desire to use a smartphone, depression, impulsivity, and anxiety. Baseline/post-intervention evaluation and the ABA' single-case experimental design were used. The study consisted of the baseline phase (A), pre-evaluation, intervention phase (B), post-evaluation, and baseline phase (A'). Six participants were enrolled, and the main outcome variables were daily changes in the desire to use a smartphone and changes in depression, impulsivity, and anxiety after the program. Prior to the intervention, all six participants had mild to moderate depression, but after the intervention, three were normal, two had mild depression, and only one had moderate depression. Impulsivity and anxiety scores decreased after the intervention, with anxiety scores showing the most dramatic change. The percentage of non-overlapping data for the baseline phase (A)-intervention phase (B) was more than 75% and that for baseline phase (A)-baseline phase (A') was 100% for all 6 participants. This study presented a good protocol for people with low access to psychological therapy. We expect the findings will be highly useful for people suffering from psychological difficulties due to smartphone addiction.

• Korean Journal of Biological Psychiatry
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• v.14 no.1
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• pp.5-13
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• 2007

Objectives : Depression disturbs the individual life from the loss of productivity to suicide. Furthermore the whole society is also influenced by depression in social and economic areas. Many scientific treatment methods are known to be effective in depression. But in reality more than half of patients with depression prefer self help treatment rather than medically based treatment. For the patients with mild depression and primary physicians, it is reasonable to provide the evidence based self care including self help or alternative treatment. This study is supported by the Korean Health 21 R&D Project for the Depression Center to establish the Korean treatment guideline for depression. Methods : The members of Depression Center including the authors attended the workshops where the methods of evidence based medicine such as literature search, quality evaluation of the articles, making the level of evidence were educated. The professional librarians helped the authors for get the searched articles. Among the total of 354 abstracts of systemic review and 300 abstracts of random controlled trials, 3 systemic reviews and 2 random controlled trials were the main structure of evaluation. Result : Among the 37 self care methods known to be effective for depression, 11 kinds of methods were worth of evaluation. The first step for the self care of mild depression is to use St. John's wort, exercise, bibliotherapy, and light therapy in depression during winter season. Acupuncture, negative ion therapy, massage, relaxation technique are known to be efective with evidence. Music therapy, hypnotherapy, and aromatherapy are known to be effective but until now the evidences is insufficient and further evaluations are needed. Conclusion : Among 11 listed self-care methods, several methods need more evidence especially in Korean situation. Exercise is the most recommendable evidence based self care method in Korea nowadays. St. John's wort is effective with evidence, but it is not the OTC drug in Korea, so it is not recommendable now. For the bibliotherapy, there is no book such as "Feeling Good" in Korea. Only the introductory book about depression is available. Publishing the self help book based upon cognitive behavioral approach or psychodynamic approach is needed. Light therapy is practiced in a few clinics, but not self-help style. Exposure to the sunlight is recommended in the level of commen sense. These self care methods are for the mild patient. Moderate to severe patients with depression should seek the professional treatment.

• Korean Journal of Adult Nursing
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• v.19 no.5
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• pp.104-114
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• 2007

Purpose: This study was conducted to develop and evaluate a dementia prevention intervention program for the elderly with mild cognitive disorder. Methods: The study was nonequivalent control group pretest-posttest design. The subjects of the study were a total of 68 elderly who ranged from 21 to 24 of total scores of K-MMSE, aged over 65, in home. The program consisted of music therapy, humor therapy, art therapy, dancing therapy, recreation, and health education to enhance brain function. The program was applied to the experimental group twice a week, ninety minutes per session for eight weeks. The data were analysed by using chi-square test and t-test. Results: The variables measured in the experimental group and the control group before the intervention were not significantly different in the homogeneity test. The dementia prevention program improved the cognition(t=9.243, p<.001), self-esteem(t=.4.336, p<.001), quality of life(t=8.375, p<.001) and reduced depression(t=-3.913, p<.001). Conclusion: These findings confirmed that the dementia prevention program made a contribution to improving cognitive function, self-esteem, and quality of life and also to reduce depression in the elderly with mild cognition disorder. Therefore, it is recommended that this program could be used in clinical practice as an effective nursing intervention for the elderly with mild cognitive disorder.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.311-319
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• 2019

The purpose of this study was to evaluate the effects of a computerized cognitive training(CCT) on cognitive, depression, life satisfaction and activity of daily living in older adults with mild dementia. The participants were 32 older adults diagnosed with mild dementia who reside in nursing hospital and were randomly divided into an 16 for an experimental group and 16 for a control group. A CCT was performed for a day/week for 8 weeks in an experimental group. The CoTras-G was used for CCT. The MMSE-K, SGDS-K, ELS and BI were administered to the experimental group and the control group in the same way in order to examine the effects of CCT. The difference of the effects between before and after a CCT conduction were identified by paired t-test. Moreover, the Mann-Whitney U-test was conducted to identify differences in variances between groups. Only participants in the experimental group reported significant improvements in cognitive function, depression, life satisfaction and activity of daily living when compared to those in the control group after CCT. There was a significant difference in cognitive function, depression, life satisfaction and activity of daily living between the experimental group and the control group after CCT. These findings suggest that the CCT can be used as effective cognitive training program to improve cognitive function, depression, life satisfaction and activity of daily living in older adults with mild dementia.

• Research in Community and Public Health Nursing
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• v.30 no.4
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• pp.550-559
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• 2019

Purpose: The purpose of this study was to verify the effects of the integrated dementia managing programme for the elderly with mild dementia in which the physiological, cognitive, emotional, sociological and spiritual aspects have considered. Methods: This study employed non-equivalent control group pre-post tests with the repeated measure design. The subjects of the study were 39 elderly with mild dementia (20 in the experimental group and 19 in the control group) who have admitted to two nursing homes in B city. The data were analyzed by repeated measures ANOVA. Results: There were significant interactions between two groups and times in self-efficacy (p=.011), cognitive function (p<.001), depression (p=.005), spiritual well-being (p=.002), and quality of life (p=.037). The integrated dementia managing programme of this study showed significant positive effects on the quality of life for the elderly with mild dementia. Conclusion: On considering the current trends of aging and increasing number of the elderly with dementia, this integrated programme would be highly recommended to be used in nursing homes for the elderly with mild dementia, and contribute to improving their quality of life, and saving the social and medical expenses as well.